Risk for alcohol use problems in severe mental illness: Interactions with sex and racial/ethnic minority status

Authors: Levit, Jeremy D., Meyers, Jacquelyn L., Georgakopoulos, Penelope, Pato, Michele T.

Source: Journal of affective disorders. 325:329-336

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100180942405.0x000001&indx=1&recIds=ETOCvdc_100180942405.0x000001

Association of parental divorce, discord, and polygenic risk with children's alcohol initiation and lifetime risk for alcohol use disorder

Authors: Kuo, Sally I‐Chun, Thomas, Nathaniel S., Aliev, Fazil, Bucholz, Kathleen K., Dick, Danielle M., McCutcheon, Vivia V., Meyers, Jacquelyn L., Chan, Grace, Kamarajan, Chella, Kramer, John R., Hesselbrock, Victor, Plawecki, Martin H., Porjesz, Bernice, Tischfield, Jay, Salvatore, Jessica E.

Source: Alcoholism. 47(4):724-735

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181384646.0x000001&indx=1&recIds=ETOCvdc_100181384646.0x000001

Associations of parent–adolescent closeness with P3 amplitude, frontal theta, and binge drinking among offspring with high risk for alcohol use disorder

Authors: Pandey, Gayathri, Kuo, Sally I‐Chun, Horne‐Osipenko, Kristina A., Pandey, Ashwini K., Kamarajan, Chella, Viteri, Stacey Saenz, Kinreich, Sivan, Chorlian, David B., Kuang, Weipeng, Stephenson, Mallory, Kramer, John, Anokhin, Andrey, Zang, Yong, Kuperman, Samuel, Hesselbrock, Victor, Schuckit, Marc, Dick, Danielle, Chan, Grace, McCutcheon, Vivia V., Edenberg, Howard, Bucholz, Kathleen K., Meyers, Jacquelyn L., Porjesz, Bernice

Source: Alcoholism. 47(1):155-167

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175727699.0x000001&indx=1&recIds=ETOCvdc_100175727699.0x000001

High Polygenic Risk Scores Are Associated With Early Age of Onset of Alcohol Use Disorder in Adolescents and Young Adults at Risk

Authors: Porjesz, B., Hesselbrock, V., Foroud, T., Agrawal, A., Dick, D., Edenberg, H.J., Nurnberger, J., Jr., Liu, Y., Kuperman, S., Kramer, J., Meyers, J., Kamarajan, C., Pandey, A., Bierut, L., Rice, J., Bucholz, K., Schuckit, M., Tischfield, J., Brooks, A., Hart, R., Almasy, L., Salvatore, J., Goate, A., Kapoor, M., Slesinger, P., Scott, D., Bauer, L., Wetherill, L., Xuei, X., Lai, D., O’Connor, S., Plawecki, M., Zang, Y., Acion, L., Chan, G., Chorlian, D.B., Zhang, J., Kinreich, S., Pandey, G., Chao, M., Anokhin, A., McCutcheon, V., Saccone, S., Aliev, F., Barr, P., Chin, H., Parsian, A., Nurnberger, John I., Jr., Wang, Yumin, Zang, Yong, Lai, Dongbing, Wetherill, Leah, Edenberg, Howard J., Aliev, Fazil, Plawecki, Martin H., Chorlian, David, Chan, Grace, Bucholz, Kathleen, Bauer, Lance, Kamarajan, Chella, Salvatore, Jessica E., Kapoor, Manav, Hesselbrock, Victor, Dick, Danielle, Bierut, Laura, McCutcheon, Vivia, Meyers, Jacquelyn L., Porjesz, Bernice, Kramer, John, Kuperman, Samuel, Kinreich, Sivan, Anokhin, Andrey P.

Source: In Biological Psychiatry Global Open Science October 2022 2(4):379-388

Prevalence, Comorbidity, and Sociodemographic Correlates of Psychiatric Diagnoses Reported in the All of Us Research Program

Authors: Barr, Peter B., Bigdeli, Tim B., Meyers, Jacquelyn L.

Source: JAMA PSYCHIATRY. 79(6):622-628

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632607501&indx=1&recIds=ETOCRN632607501

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The collaborative study on the genetics of alcoholism: Brain function.

Authors: Meyers, Jacquelyn L.¹ (AUTHOR) Jacquelyn.Meyers@downstate.edu, Brislin, Sarah J.² (AUTHOR) sarah.brislin@rutgers.edu, Kamarajan, Chella¹ (AUTHOR), Plawecki, Martin H.³ (AUTHOR), Chorlian, David¹ (AUTHOR), Anohkin, Andrey⁴ (AUTHOR), Kuperman, Samuel⁵ (AUTHOR), Merikangas, Alison^6,7,8 (AUTHOR), Pandey, Gayathri¹ (AUTHOR), Kinreich, Sivan¹ (AUTHOR), Pandey, Ashwini¹ (AUTHOR), Edenberg, Howard J.⁹ (AUTHOR), Bucholz, Kathleen K.⁴ (AUTHOR), Almasy, Laura^6,7,8 (AUTHOR), Porjesz, Bernice¹ (AUTHOR) Bernice.Porjesz@downstate.edu

Source: Genes, Brain & Behavior. Oct2023, Vol. 22 Issue 5, p1-16. 16p.

Subject Terms: *ALCOHOLISM, *GENETICS, *ALCOHOL drinking, *ETHNICITY, *GENETIC variation, *RACE

A latent class analysis of alcohol and posttraumatic stress symptoms among offspring of parents with and without alcohol use disorder

Authors: Bender, Annah K., Meyers, Jacquelyn L., di Viteri, Stacey Subbie-Saenz, Schuckit, Marc, Chan, Grace, Acion, Laura, Kamarajan, Chella, Kramer, John, Anohkin, Andrey, Kinreich, Sivan, Pandey, Ashwini, Hesselbrock, Victor, Hesselbrock, Michie, Bucholz, Kathleen K., McCutcheon, Vivia V.

Source: In Addictive Behaviors January 2021 112

The Associations Between Polygenic Risk, Sensation Seeking, Social Support, and Alcohol Use in Adulthood

Authors: Su, Jinni, Kuo, Sally I-Chun, Aliev, Fazil, Chan, Grace, Edenberg, Howard J., Kamarajan, Chella, McCutcheon, Vivia V., Meyers, Jacquelyn L., Schuckit, Marc, Tischfield, Jay

Source: Journal of abnormal psychology. 130(5):525-536

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN627453083&indx=1&recIds=ETOCRN627453083

Genetic and Social-Environmental Influences on Substance Use and Disorders

Authors: Meyers, Jacquelyn L., Salvatore, Jessica E.

Source: Psychiatric annals. 51(4):170-174

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626400551&indx=1&recIds=ETOCRN626400551

Genome‐wide admixture mapping of DSM‐IV alcohol dependence, criterion count, and the self‐rating of the effects of ethanol in African American populations

Authors: Lai, Dongbing, Kapoor, Manav, Wetherill, Leah, Schwandt, Melanie, Ramchandani, Vijay A., Goldman, David, Chao, Michael, Almasy, Laura, Bucholz, Kathleen, Hart, Ronald P., Kamarajan, Chella, Meyers, Jacquelyn L., Nurnberger, John I., Tischfield, Jay, Edenberg, Howard J., Schuckit, Marc, Goate, Alison, Scott, Denise M., Porjesz, Bernice, Agrawal, Arpana, Foroud, Tatiana

Source: American journal of medical genetics.Part B.Neuropsychiatric genetics. 186(3):151-161

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121062967.0x000001&indx=1&recIds=ETOCvdc_100121062967.0x000001

Associations between Suicidal Thoughts and Behaviors and Genetic Liability for Cognitive Performance, Depression, and Risk-Taking in a High-Risk Sample

Authors: Johnson, Emma C., Aliev, Fazil, Meyers, Jacquelyn L., Salvatore, Jessica E., Tillman, Rebecca, Chang, Yoonhoo, Docherty, Anna R., Bogdan, Ryan, Acion, Laura, Chan, Grace, Chorlian, David B., Kamarajan, Chella, Kuperman, Samuel, Pandey, Ashwini, Plawecki, Martin H., Schuckit, Marc, Tischfield, Jay, Edenberg, Howard J., Bucholz, Kathleen K., Nurnberger, John I., Porjesz, Bernice, Hesselbrock, Victor, Dick, Danielle M., Kramer, John R., Agrawal, Arpana

Source: Complex psychiatry. 7(1/2):34-44

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128273164.0x000001&indx=1&recIds=ETOCvdc_100128273164.0x000001

Childhood trauma is associated with developmental trajectories of EEG coherence, alcohol-related outcomes, and PTSD symptoms.

Authors: Neale, Zoe E., Bountress, Kaitlin, Sheerin, Christina, Viteri, Stacey Saenz de, Cusack, Shannon, Chorlian, David, Barr, Peter B., Kaplan, Isabelle, Pandey, Gayathri, Osipenko, Kristina A., McCutcheon, Vivia, Kuo, Sally I-Chun, Cooke, Megan E., Brislin, Sarah J., Salvatore, Jessica E., Kamarajan, Chella, Porjesz, Bernice, Amstadter, Ananda B., Meyers, Jacquelyn L., Investigators, COGA

Source: Psychological Medicine; Nov2024, Vol. 54 Issue 15, p1-14, 14p

Subject Terms: ADOLESCENT development, POST-traumatic stress disorder, RISK assessment, WOUNDS & injuries, CHILD psychopathology, RESEARCH funding, ELECTROENCEPHALOGRAPHY, NEURAL development, SEX distribution, ALCOHOL-induced disorders, ADVERSE childhood experiences, ADOLESCENCE

A large-scale genome-wide association study meta-analysis of cannabis use disorder

Authors: Walters, Raymond, Polimanti, Renato, Johnson, Emma, McClintick, Jeanette, Hatoum, Alexander, He, June, Wendt, Frank, Zhou, Hang, Adams, Mark, Adkins, Amy, Aliev, Fazil, Bacanu, Silviu-Alin, Batzler, Anthony, Bertelsen, Sarah, Biernacka, Joanna, Bigdeli, Tim, Chen, Li-Shiun, Clarke, Toni-Kim, Chou, Yi-Ling, Degenhardt, Franziska, Docherty, Anna, Edwards, Alexis, Fontanillas, Pierre, Foo, Jerome, Fox, Louis, Frank, Josef, Giegling, Ina, Gordon, Scott, Hack, Laura, Hartmann, Annette, Hartz, Sarah, Heilmann-Heimbach, Stefanie, Herms, Stefan, Hodgkinson, Colin, Hoffman, Per, Hottenga, Jouke, Kennedy, Martin, Alanne-Kinnunen, Mervi, Konte, Bettina, Lahti, Jari, Lahti-Pulkkinen, Marius, Lai, Dongbing, Ligthart, Lannie, Loukola, Anu, Maher, Brion, Mbarek, Hamdi, McIntosh, Andrew, McQueen, Matthew, Meyers, Jacquelyn, Milaneschi, Yuri, Palviainen, Teemu, Pearson, John, Peterson, Roseann, Ripatti, Samuli, Ryu, Euijung, Saccone, Nancy, Salvatore, Jessica, Sanchez-Roige, Sandra, Schwandt, Melanie, Sherva, Richard, Streit, Fabian, Strohmaier, Jana, Thomas, Nathaniel, Wang, Jen-Chyong, Webb, Bradley, Wedow, Robbee, Wetherill, Leah, Wills, Amanda, Boardman, Jason, Chen, Danfeng, Choi, Doo-Sup, Copeland, William, Culverhouse, Robert, Dahmen, Norbert, Degenhardt, Louisa, Domingue, Benjamin, Elson, Sarah, Frye, Mark, Gäbel, Wolfgang, Hayward, Caroline, Ising, Marcus, Keyes, Margaret, Kiefer, Falk, Kramer, John, Kuperman, Samuel, Lucae, Susanne, Lynskey, Michael, Maier, Wolfgang, Mann, Karl, Männistö, Satu, Müller-Myhsok, Bertram, Murray, Alison, Nurnberger, John, Palotie, Aarno, Preuss, Ulrich, Räikkönen, Katri, Reynolds, Maureen, Ridinger, Monika, Scherbaum, Norbert, Schuckit, Marc, Soyka, Michael, Treutlein, Jens, Witt, Stephanie, Wodarz, Norbert, Zill, Peter, Adkins, Daniel, Boden, Joseph, Boomsma, Dorret, Bierut, Laura, Brown, Sandra, Bucholz, Kathleen, Cichon, Sven, Costello, E. Jane, de Wit, Harriet, Diazgranados, Nancy, Dick, Danielle, Eriksson, Johan, Farrer, Lindsay, Foroud, Tatiana, Gillespie, Nathan, Goate, Alison, Goldman, David, Grucza, Richard, Hancock, Dana, Harris, Kathleen Mullan, Heath, Andrew, Hesselbrock, Victor, Hewitt, John, Hopfer, Christian, Horwood, John, Iacono, William, Johnson, Eric, Kaprio, Jaakko, Karpyak, Victor, Kendler, Kenneth, Kranzler, Henry, Krauter, Kenneth, Lichtenstein, Paul, Lind, Penelope, McGue, Matt, MacKillop, James, Madden, Pamela, Maes, Hermine, Magnusson, Patrik, Martin, Nicholas, Medland, Sarah, Montgomery, Grant, Nelson, Elliot, Nöthen, Markus, Palmer, Abraham, Pederson, Nancy, Penninx, Brenda, Porjesz, Bernice, Rice, John, Rietschel, Marcella, Riley, Brien, Rose, Richard, Rujescu, Dan, Shen, Pei-Hong, Silberg, Judy, Stallings, Michael, Tarter, Ralph, Vanyukov, Michael, Vrieze, Scott, Wall, Tamara, Whitfield, John, Zhao, Hongyu, Neale, Benjamin, Gelernter, Joel, Edenberg, Howard, Agrawal, Arpana, Johnson, Emma C ^{*, *}, Demontis, Ditte ^*, Thorgeirsson, Thorgeir E ^*, Walters, Raymond K, Hatoum, Alexander S, Paul, Sarah E, Wendt, Frank R, Reginsson, Gunnar W, Baranger, David A A, Gudbjartsson, Daniel F, Adkins, Daniel E, Adkins, Amy E, Alexander, Jeffry, Bigdeli, Tim B, Brown, Sandra A, Bucholz, Kathleen K, Bybjerg-Grauholm, Jonas, Corley, Robin P, Dick, Danielle M, Domingue, Benjamin W, Goate, Alison M, Gordon, Scott D, Hack, Laura M, Hancock, Dana B, Hartz, Sarah M, Hickie, Ian B, Hougaard, David M, Lind, Penelope A, McClintick, Jeanette N, McQueen, Matthew B, Meyers, Jacquelyn L, Montgomery, Grant W, Mors, Ole, Mortensen, Preben B, Nordentoft, Merete, Pearson, John F, Peterson, Roseann E, Reynolds, Maureen D, Rice, John P, Runarsdottir, Valgerdur, Saccone, Nancy L, Silberg, Judy L, Tarter, Ralph E, Tyrfingsson, Thorarinn, Wall, Tamara L, Webb, Bradley T, Werge, Thomas, Wright, Margaret J, Zellers, Stephanie, Adams, Mark J, Bierut, Laura J, Boardman, Jason D, Copeland, William E, Farrer, Lindsay A, Foroud, Tatiana M, Gillespie, Nathan A, Grucza, Richard A, Heath, Andrew C, Hewitt, John K, Hopfer, Christian J, Iacono, William G, Johnson, Eric O, Kendler, Kenneth S, Kennedy, Martin A, Kranzler, Henry R, Madden, Pamela A F, Maes, Hermine H, Maher, Brion S, Martin, Nicholas G, McGue, Matthew, McIntosh, Andrew M, Medland, Sarah E, Nelson, Elliot C, Riley, Brien P, Stallings, Michael C, Vanyukov, Michael M, Davis, Lea K, Bogdan, Ryan, Edenberg, Howard J, Stefansson, Kari, Børglum, Anders D

Source: In The Lancet Psychiatry December 2020 7(12):1032-1045

Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations

Authors: Peterson, Roseann E., Kuchenbaecker, Karoline, Walters, Raymond K., Chen, Chia-Yen, Popejoy, Alice B., Periyasamy, Sathish, Lam, Max, Iyegbe, Conrad, Strawbridge, Rona J., Brick, Leslie, Carey, Caitlin E., Martin, Alicia R., Meyers, Jacquelyn L., Su, Jinni, Chen, Junfang, Edwards, Alexis C., Kalungi, Allan, Koen, Nastassja, Majara, Lerato, Schwarz, Emanuel, Smoller, Jordan W., Stahl, Eli A., Sullivan, Patrick F., Vassos, Evangelos, Mowry, Bryan, Prieto, Miguel L., Cuellar-Barboza, Alfredo, Bigdeli, Tim B., Edenberg, Howard J., Huang, Hailiang, Duncan, Laramie E.

Source: In Cell 17 October 2019 179(3):589-603

A large-scale genome-wide association study meta-analysis of cannabis use disorder

Authors: Johnson, Emma C, Demontis, Ditte, Thorgeirsson, Thorgeir E, Walters, Raymond K, Polimanti, Renato, Hatoum, Alexander S, Sanchez-Roige, Sandra, Paul, Sarah E, Wendt, Frank R, Clarke, Toni-Kim, Lai, Dongbing, Reginsson, Gunnar W, Zhou, Hang, He, June, Baranger, David A A, Gudbjartsson, Daniel F, Wedow, Robbee, Adkins, Daniel E, Adkins, Amy E, Alexander, Jeffry, Bacanu, Silviu-Alin, Bigdeli, Tim B, Boden, Joseph, Brown, Sandra A, Bucholz, Kathleen K, Bybjerg-Grauholm, Jonas, Corley, Robin P, Degenhardt, Louisa, Dick, Danielle M, Domingue, Benjamin W, Fox, Louis, Goate, Alison M, Gordon, Scott D, Hack, Laura M, Hancock, Dana B, Hartz, Sarah M, Hickie, Ian B, Hougaard, David M, Krauter, Kenneth, Lind, Penelope A, McClintick, Jeanette N, McQueen, Matthew B, Meyers, Jacquelyn L, Montgomery, Grant W, Mors, Ole, Mortensen, Preben B, Nordentoft, Merete, Pearson, John F, Peterson, Roseann E, Reynolds, Maureen D, Rice, John P, Runarsdottir, Valgerdur, Saccone, Nancy L, Sherva, Richard, Silberg, Judy L, Tarter, Ralph E, Tyrfingsson, Thorarinn, Wall, Tamara L, Webb, Bradley T, Werge, Thomas, Wetherill, Leah, Wright, Margaret J, Zellers, Stephanie, Adams, Mark J, Bierut, Laura J, Boardman, Jason D, Copeland, William E, Farrer, Lindsay A, Foroud, Tatiana M, Gillespie, Nathan A, Grucza, Richard A, Harris, Kathleen Mullan, Heath, Andrew C, Hesselbrock, Victor, Hewitt, John K, Hopfer, Christian J, Horwood, John, Iacono, William G, Johnson, Eric O, Kendler, Kenneth S, Kennedy, Martin A, Kranzler, Henry R, Madden, Pamela A F, Maes, Hermine H, Maher, Brion S, Martin, Nicholas G, McGue, Matthew, McIntosh, Andrew M, Medland, Sarah E, Nelson, Elliot C, Porjesz, Bernice, Riley, Brien P, Stallings, Michael C, Vanyukov, Michael M, Vrieze, Scott, Davis, Lea K, Bogdan, Ryan, Gelernter, Joel, Edenberg, Howard J, Stefansson, Kari, Børglum, Anders D, Agrawal, Arpana

Source: Lancet.Psychiatry. 7(12):1032-1045

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111034748.0x000001&indx=1&recIds=ETOCvdc_100111034748.0x000001

Shared Molecular Genetic Risk of Alcohol Dependence and Posttraumatic Stress Disorder (PTSD)

Authors: Sheerin, Christina M., Bountress, Kaitlin E., Meyers, Jacquelyn L., de Viteri, Stacey Subbie Saenz, Shen, Hanyang, Maihofer, Adam X., Duncan, Laramie E., Amstadter, Ananda B.

Source: Psychology of addictive behaviors. 34(5):613-619

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN624362078&indx=1&recIds=ETOCRN624362078

Density and Dichotomous Family History Measures of Alcohol Use Disorder as Predictors of Behavioral and Neural Phenotypes: A Comparative Study Across Gender and Race/Ethnicity

Authors: Pandey, Gayathri, Seay, Michael J., Meyers, Jacquelyn L., Chorlian, David B., Pandey, Ashwini K., Kamarajan, Chella, Ehrenberg, Morton, Pitti, Daniel, Kinreich, Sivan, Subbie‐Saenz de Viteri, Stacey, Acion, Laura, Anokhin, Andrey, Bauer, Lance, Chan, Grace, Edenberg, Howard, Hesselbrock, Victor, Kuperman, Samuel, McCutcheon, Vivia V., Bucholz, Kathleen K., Schuckit, Marc, Porjesz, Bernice

Source: Alcoholism. 44(3):697-710

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100102860215.0x000001&indx=1&recIds=ETOCvdc_100102860215.0x000001

Sibling comparisons elucidate the associations between educational attainment polygenic scores and alcohol, nicotine and cannabis

Authors: Salvatore, Jessica E., Barr, Peter B., Stephenson, Mallory, Aliev, Fazil, Kuo, Sally I‐Chun, Su, Jinni, Agrawal, Arpana, Almasy, Laura, Bierut, Laura, Bucholz, Kathleen, Chan, Grace, Edenberg, Howard J., Johnson, Emma C., McCutcheon, Vivia V., Meyers, Jacquelyn L., Schuckit, Marc, Tischfield, Jay, Wetherill, Leah, Dick, Danielle M.

Source: Addiction. 115(2):337-346

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100149733390.0x000001&indx=1&recIds=ETOCvdc_100149733390.0x000001

Alcohol milestones and internalizing, externalizing, and executive function: longitudinal and polygenic score associations.

Authors: Paul, Sarah E., Baranger, David A.A., Johnson, Emma C., Jackson, Joshua J., Gorelik, Aaron J., Miller, Alex P., Hatoum, Alexander S., Thompson, Wesley K., Strube, Michael, Dick, Danielle M., Kamarajan, Chella, Kramer, John R., Plawecki, Martin H., Chan, Grace, Anokhin, Andrey P., Chorlian, David B., Kinreich, Sivan, Meyers, Jacquelyn L., Porjesz, Bernice, Edenberg, Howard J.

Source: Psychological Medicine; Jul2024, Vol. 54 Issue 10, p1-14, 14p

Subject Terms: EXECUTIVE function, SEX distribution, QUESTIONNAIRES, INTERNALIZING behavior, ALCOHOL-induced disorders, GENETIC risk score, ALCOHOL drinking, EXTERNALIZING behavior, DRINKING behavior, MENTAL depression