Results from the UNITED study: a multicenter study validating the prognostic effect of the tumor–stroma ratio in colon cancer

Authors: Petrushevska, Gordana, Bogdanovska, Magdalena, Zdravkoski, Panche, Antovic, Svetozar, Dzambaz, Darko, Karagjozov, Panche, de Cuba, Erienne M.V., Beverdam, Frédérique, Jansen, Jan, Vermaas, Maarten, Gašljević, Gorana, Kjær-Frifeldt, Sanne, Lindebjerg, Jan, Strous, Maud, Vogelaar, Jeroen F., Bulkmans, Nicole W.J., van Baarlen, Joop, Mekenkamp, Leonie, Hoekstra, Ronald, Sie, Mark, Cuatrecasas, Miriam, Simonetti, Sara, Rodrigo, María Teresa, Sanz, Iván Archilla, Guerrero Pineda, Jose, Leeuwis-Fedorovich, Natalja E., Talsma, Koen A., Souza da Silva, Ricella M., Lacle, Miangela M., Koopman, Miriam, Dekker, Jan Willem T., van Tilburg, Arjan, Nuciforo, Paolo, Villalobos Alberú, Xenia, Landolfi, Stefania, Zucchiatti, Adriana, Witteveen, Emma, Bordbar, Arad, Hendriks, Mathijs P., Arensman, René, Natu, Shonali, Maka, Noori, Mesker, Wilma E., Tollenaar, Rob A.E.M., Polack, Meaghan, Smit, Marloes A., van Pelt, Gabi W., Putter, Hein, Meershoek-Kleinenbarg, Elma, Roodvoets, Annet G.H., Crobach, Augustinus S.L.P., Gelderblom, Hans, Fontes e Sousa, Mário, Borralho Nunes, Paula, Cruz, João, Raimundo, Ana, Silva, Nelson, Brito, Maria J., Terpstra, Valeska, Zakhartseva, L.M., Al Dieri, Raed, Fléjou, Jean-François, Feakins, Roger, Dequeker, Els, Vink, Geraldine R., van Krieken, J.Han J.M., Polack, M., Smit, M.A., van Pelt, G.W., Roodvoets, A.G.H., Meershoek-Klein Kranenbarg, E., Putter, H., Gelderblom, H., Crobach, A.S.L.P., Terpstra, V., Petrushevska, G., Gašljević, G., Kjær-Frifeldt, S., de Cuba, E.M.V., Bulkmans, N.W.J., Vink, G.R., Al Dieri, R., Tollenaar, R.A.E.M., van Krieken, J.H.J.M., Mesker, W.E.

Source: In ESMO Open April 2024 9(4)

Longitudinal changes of serum protein N-Glycan levels for earlier detection of pancreatic cancer in high-risk individuals

Authors: Levink, I.J.M., Klatte, D.C.F., Hanna-Sawires, R.G., Vreeker, G.C.M., Ibrahim, I.S., van der Burgt, Y.E.M., Overbeek, K.A., Koopmann, B.D.M., Cahen, D.L., Fuhler, G.M., Wuhrer, M., Bonsing, B.A., Tollenaar, R.A.E.M., Vleggaar, F.P., Vasen, H.F.A., van Leerdam, M.E., Bruno, M.J., Mesker, W.E.

Source: Pancreatology. 22(4):497-506

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100162162858.0x000001&indx=1&recIds=ETOCvdc_100162162858.0x000001

The value of tumor-stroma ratio as predictor of pathologic response after neoadjuvant chemoradiotherapy in esophageal cancer

Authors: van Pelt, G.W., Krol, J.A., Lips, I.M., Peters, F.P., van Klaveren, D., Boonstra, J.J., de Steur, W.O., Tollenaar, R.A.E.M., Farina Sarasqueta, A., Mesker, W.E., Slingerland, M.

Source: In Clinical and Translational Radiation Oncology January 2020 20:39-44

Disorganised stroma determined on pre-treatment breast cancer biopsies is associated with poor response to neoadjuvant chemotherapy: Results from the NEOZOTAC trial

Authors: Dekker, T.J.A., Charehbili, A., Smit, V.T.H.B.M., ten Dijke, P., Meershoek-Klein Kranenbarg, E., van de Velde, C.J.H., Nortier, J.W.R., Tollenaar, R.A.E.M., Mesker, W.E., Kroep, J.R.

Source: In Molecular Oncology June 2015 9(6):1120-1128

Quantitative assessment of lymph vascular space invasion (LVSI) provides important prognostic information in node-negative breast cancer

Authors: Dekker, T.J.A., van de Velde, C.J.H., van Bruggen, D., Mesker, W.E., van der Hoeven, J.J.M., Kroep, J.R., Tollenaar, R.A.E.M., Smit, V.T.H.B.M. ^*

Source: In Annals of Oncology December 2013 24(12):2994-2998

Reliability of core needle biopsy for determining ER and HER2 status in breast cancer

Authors: Dekker, T.J.A. ^*, Smit, V.T.H.B.M., Hooijer, G.K.J., Van de Vijver, M.J., Mesker, W.E., Tollenaar, R.A.E.M., Nortier, J.W.R., Kroep, J.R.

Source: In Annals of Oncology April 2013 24(4):931-937

The prognostic role of TGF-β signaling pathway in breast cancer patients

Authors: de Kruijf, E.M., Dekker, T.J.A., Hawinkels, L.J.A.C., Putter, H., Smit, V.T.H.B.M., Kroep, J.R., Kuppen, P.J.K., van de Velde, C.J.H., ten Dijke, P., Tollenaar, R.A.E.M., Mesker, W.E. ^*

Source: In Annals of Oncology February 2013 24(2):384-390

The proportion of tumor-stroma as a strong prognosticator for stage II and III colon cancer patients: validation in the VICTOR trial

Authors: Huijbers, A., Tollenaar, R.A.E.M., v Pelt, G.W., Zeestraten, E.C.M., Dutton, S., McConkey, C.C., Domingo, E., Smit, V.T.H.B.M., Midgley, R., Warren, B.F., Johnstone, E.C., Kerr, D.J., Mesker, W.E. ^*

Source: In Annals of Oncology January 2013 24(1):179-185

Multicenter Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI MSI) Identifies Proteomic Differences in Breast-Cancer-Associated Stroma

Authors: Dekker, T.J.A., Balluff, B.D., Jones, E.A., Schone, C.D., Schmitt, M., Aubele, M., Kroep, J.R., Smit, V.T.H.B.M., Tollenaar, R.A.E.M., Mesker, W.E.

Source: JOURNAL OF PROTEOME RESEARCH. 13(11):4730-4738

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN364799640&indx=1&recIds=ETOCRN364799640

Presence of a high amount of stroma and downregulation of SMAD4 predict for worse survival for stage I-II colon cancer patients

Authors: Mesker, W.E., Liefers, G.-J., Junggeburt, J.M.C., van Pelt, G.W., Alberici, P., Kuppen, P.J.K., Miranda, N.F., van Leeuwen, K.A.M., Morreau, H., Szuhai, K.

Source: CELLULAR ONCOLOGY. 31(3):169-178

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN252123706&indx=1&recIds=ETOCRN252123706

PV-0623 Tumor-stroma ratio for predicting pathologic response after chemoradiotherapy in esophageal cancer

Authors: Lips, I., Van Pelt, G.W., Peters, F.P., Krol, J.A., Van Klaveren, D., Boonstra, J.J., De Steur, W.O., Farina Sarasqueta, A., Mesker, W.E., Slingerland, M.

Source: Radiotherapy and oncology. 133(S1):S331-S332

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100081432856.0x000001&indx=1&recIds=ETOCvdc_100081432856.0x000001

Tumor-Stroma Ratio within the Primary Tumor Is a Prognostic Factor in Early Breast Cancer Patients, Especially in Triple-Negative-Carcinoma Patients
San Antonio breast cancer symposium; CTRC-AACR

Authors: de Kruijf, E.M., van Nes, J.G.H., van de Velde, C.J.H., Putter, H., Smit, V.T.H.B.M., Liefers, G.J., Kuppen, P.J.K., Tollenaar, R.A.E.M., Mesker, W.E.

Source: CANCER RESEARCH. 69(24):3049-3049

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCCN074768397&indx=1&recIds=ETOCCN074768397

Carcinoma-stroma ratio is a prognostic factor in early breast cancer patients
European Society of Surgical Oncology

Authors: de Kruijf, E.M., van Nes, J.G., Mesker, W.E., van Pelt, G., Putter, H., Smit, V.T., Liefers, G.J., van de Velde, C.J., Tollenaar, R., Kuppen, P.J.

Source: EUROPEAN JOURNAL OF SURGICAL ONCOLOGY. 34(9):72-72

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCCN070000943&indx=1&recIds=ETOCCN070000943

192 (PB-093) - The prognostic value of the tumour-stroma ratio in invasive breast carcinoma

Authors: Mesker, W.E., Vangangelt, K., Tollenaar, R.

Source: In European Journal of Cancer April 2018 92 Supplement 3:S48-S48

On the use of double cross-validation for the combination of proteomic mass spectral data for enhanced diagnosis and prediction

Authors: Mertens, B.J.A., van der Burgt, Y.E.M., Velstra, B., Mesker, W.E., Tollenaar, R.A.E.M., Deelder, A.M.

Source: In Statistics and Probability Letters 2011 81(7):759-766

Excellent prognosis of node negative patients after sentinel node procedure in colon carcinoma: A 5-year follow-up study.

Authors: Braat, A.E., Pol, R.A., Oosterhuis, J.W.A., de Vries, J.E., Mesker, W.E., Tollenaar, R.A.E.M.

Source: European Journal of Surgical Oncology; Jun2014, Vol. 40 Issue 6, p747-755, 9p

Subject Terms: SENTINEL lymph nodes, COLON cancer prognosis, COLON cancer patients, FOLLOW-up studies (Medicine), CLINICAL trials, COHORT analysis, ONCOLOGIC surgery

Prognostic relevance of occult tumour cells in lymph nodes in colorectal cancer.

Authors: Doekhie, F.S., Kuppen, P.J.K., Peeters, K.C.M.J., Mesker, W.E., van Soest, R.A., Morreau, H., van de Velde, C.J.H., Tanke, H.J., Tollenaar, R.A.E.M.

Source: European Journal of Surgical Oncology; Apr2006, Vol. 32 Issue 3, p253-258, 6p

Subject Terms: CANCER cells, LYMPH nodes, TUMORS, CANCER treatment

The feasibility and reliability of sentinel node mapping in colorectal cancer.

Authors: Doekhie, F.S., Peeters, K.C.M.J., Kuppen, P.J.K., Mesker, W.E., Tanke, H.J., Morreau, H., van de Velde, C.J.H., Tollenaar, R.A.E.M.

Source: European Journal of Surgical Oncology; Oct2005, Vol. 31 Issue 8, p854-862, 9p

Subject Terms: COLON cancer, CANCER treatment, LYMPHATICS, CANCER patients, CANCER cells, CELLULAR pathology

6082 POSTER Stroma Production Within the Primary Tumour Correlates With Poor Survival for Stage l-ll Colon Cancer Patients

Authors: Mesker, W.E., Huijbers, A., Johnstone, E.C., Van Pelt, G.W., Midgley, R., Liefers, G.J., Morreau, J., Kerr, D.J., Tollenaar, R.A.E.M.

Source: In European Journal of Cancer 2011 47 Supplement 1:S415-S415

127 Stroma production within the primary tumour correlates with poor survival for stage I-II colon cancer patients

Authors: Mesker, W.E., Johnstone, E.C., Van Pelt, G.W., Midgley, R., Liefers, G.J., Morreau, J., Kerr, D.J., Tollenaar, R.A.E.M.

Source: In EJC Supplements 2010 8(5):33-33