Conserved helical motifs in the IKZF1 disordered region mediate NuRD interaction and transcriptional repression

Authors: Zhang, Tianyi ^{1, ∗}, Wang, Yi-Fang ¹, Montoya, Alex ¹, Patrascan, Ilinca ¹, Nebioglu, Nehir ¹, Pallikonda, Husayn A. ¹, Georgieva, Radina ¹, King, James W. D. ¹, Kramer, Holger B. ¹, Shliaha, Pavel V. ¹, Rueda, David S. ^{1, 2, ∗∗∗}, Merkenschlager, Matthias ^{1, ∗∗}

Source: In Blood 23 January 2025 145(4):422-437

Chromatin jets define the properties of cohesin-driven in vivo loop extrusion

Authors: Guo, Ya, Al-Jibury, Ediem, Garcia-Millan, Rosalba, Ntagiantas, Konstantinos, King, James W.D., Nash, Alex J., Galjart, Niels, Lenhard, Boris, Rueckert, Daniel, Fisher, Amanda G., Pruessner, Gunnar, Merkenschlager, Matthias

Source: In Molecular Cell 20 October 2022 82(20):3769-3780

Editorial overview: Genome architecture and expression

Authors: Bystricky, Kerstin, Merkenschlager, Matthias

Source: Current opinion in genetics & development. 61:iii-vi

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121113082.0x000001&indx=1&recIds=ETOCvdc_100121113082.0x000001

Three-dimensional chromatin mapping of sensory neurons reveals that promoter-enhancer looping is required for axonal regeneration.

Authors: Palmisano, Ilaria, Tong Liu, Wei Gao, Luming Zhou, Merkenschlager, Matthias, Mueller, Franziska, Chadwick, Jessica, Rivalta, Rebecca Toscano, Guiping Kong, King, James W. D., Al-jibury, Ediem, Yuyang Yan, Carlino, Alessandro, Collison, Bryce, De Vitis, Eleonora, Gongala, Sree, De Virgiliis, Francesco, Zheng Wang, Di Giovanni, Simone

Source: Proceedings of the National Academy of Sciences of the United States of America; 9/17/2024, Vol. 121 Issue 38, p1-12, 41p

Subject Terms: DORSAL root ganglia, SCIATIC nerve injuries, NERVOUS system regeneration, SENSORY neurons, GENE expression

STATegra, a comprehensive multi-omics dataset of B-cell differentiation in mouse

Authors: Gomez-Cabrero, David, Tarazona, Sonia, Ferreirós-Vidal, Isabel, Ramirez, Ricardo, Company, Carlos, Schmidt, Andreas, Reijmers, Theo, Paul, Veronica, Marabita, Francesco, Rodríguez-Ubreva, Javier, Garcia-Gomez, Antonio, Carroll, Thomas, Cooper, Lee, Liang, Ziwei, Dharmalingam, Gopuraja, Kloet, Frans, Harms, Amy, Balzano-Nogueira, Leandro, Lagani, Vincenzo, Tsamardinos, Ioannis, Lappe, Michael, Maier, Dieter, Westerhuis, Johan, Hankemeier, Thomas, Imhof, Axel, Ballestar, Esteban, Mortazavi, Ali, Merkenschlager, Matthias, Tegner, Jesper, Conesa, Ana

Source: Scientific data. 6(1):1-15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190885814.0x000001&indx=1&recIds=ETOCvdc_100190885814.0x000001

Epigenomic signatures underpin the axonal regenerative ability of dorsal root ganglia sensory neurons

Authors: Palmisano, Ilaria, Danzi, Matt, Hutson, Thomas, Zhou, Luming, McLachlan, Eilidh, Serger, Elisabeth, Shkura, Kirill, Srivastava, Prashant, Hervera, Arnau, Neill, Nick, Liu, Tong, Dhrif, Hassen, Wang, Zheng, Kubat, Miroslav, Wuchty, Stefan, Merkenschlager, Matthias, Levi, Liron, Elliott, Evan, Bixby, John, Lemmon, Vance, Giovanni, Simone

Source: Nature neuroscience. 22(11):1913-1924

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190870958.0x000001&indx=1&recIds=ETOCvdc_100190870958.0x000001

The Regulated Long-Term Delivery of Therapeutic Proteins by Using Antigen-Specific B Lymphocytes

Authors: Takács, Katalin, Du Roure, Camille, Nabarro, Stephen, Dillon, Niall, McVey, John H., Webster, Zoe, MacNeil, Angus, Bartók, István, Higgins, Christopher, Gray, David, Merkenschlager, Matthias, Fisher, Amanda G., Mak, Tak Wah

Source: Proceedings of the National Academy of Sciences of the United States of America, 2004 Nov . 101(46), 16298-16303.

Access URL: https://www.jstor.org/stable/3373812

Protein restriction during pregnancy alters Cdkn1c silencing, dopamine circuitry and offspring behaviour without changing expression of key neuronal marker genes.

Authors: Prodani, Chiara, Irvine, Elaine E., Sardini, Alessandro, Gleneadie, Hannah J., Dimond, Andrew, Van de Pette, Mathew, John, Rosalind, Kokkinou, Michelle, Howes, Oliver, Withers, Dominic J., Ungless, Mark A., Merkenschlager, Matthias, Fisher, Amanda G.

Source: Scientific Reports; 4/12/2024, Vol. 14 Issue 1, p1-16, 16p

Subject Terms: DOPAMINE receptors, DOPAMINERGIC neurons, DOPAMINE, ADULT children, POSITRON emission tomography, LOW-protein diet, TYROSINE hydroxylase

Bioluminescence imaging of Cyp1a1-luciferase reporter mice demonstrates prolonged activation of the aryl hydrocarbon receptor in the lung.

Authors: Veland, Nicolas, Gleneadie, Hannah J., Brown, Karen E., Sardini, Alessandro, Pombo, Joaquim, Dimond, Andrew, Burns, Vanessa, Sarkisyan, Karen, Schiering, Chris, Webster, Zoe, Merkenschlager, Matthias, Fisher, Amanda G.

Source: Communications Biology; 4/10/2024, Vol. 7 Issue 1, p1-13, 13p

Subject Terms: ARYL hydrocarbon receptors, LUNGS, BIOLUMINESCENCE, CYTOCHROME P-450 CYP1A1, TRANSCRIPTION factors, CELL populations

Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation

Authors: Cuartero, Sergi, Weiss, Felix, Dharmalingam, Gopuraja, Guo, Ya, Ing-Simmons, Elizabeth, Masella, Silvia, Robles-Rebollo, Irene, Xiao, Xiaolin, Wang, Yi-Fang, Barozzi, Iros, Djeghloul, Dounia, Amano, Mariane, Niskanen, Henri, Petretto, Enrico, Dowell, Robin, Tachibana, Kikuë, Kaikkonen, Minna, Nasmyth, Kim, Lenhard, Boris, Natoli, Gioacchino, Fisher, Amanda, Merkenschlager, Matthias

Source: Nature immunology. 19(9):932-941

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175669993.0x000001&indx=1&recIds=ETOCvdc_100175669993.0x000001

Three-dimensional genome organization in normal and malignant haematopoiesis

Authors: Cuartero, Sergi, Merkenschlager, Matthias

Source: Current opinion in hematology. 25(4):323-328

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100064306071.0x000001&indx=1&recIds=ETOCvdc_100064306071.0x000001

Oncometabolite Tinkers with Genome Folding, Boosting Oncogene Expression

Authors: Ing-Simmons, Elizabeth, Merkenschlager, Matthias

Source: In Trends in Molecular Medicine March 2016 22(3):185-187

Cohesin's role in pluripotency and reprogramming

Authors: Gupta, Preksha, Lavagnolli, Thais, Mira-Bontenbal, Hegias, Fisher, Amanda G., Merkenschlager, Matthias

Source: Cell cycle. 15(3):324-330

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCETOCvdc_100028955267.0x000001&indx=1&recIds=ETOCETOCvdc_100028955267.0x000001

Jarid2 Coordinates Nanog Expression and PCP/Wnt Signaling Required for Efficient ESC Differentiation and Early Embryo Development

Authors: Landeira, David, Bagci, Hakan, Malinowski, Andrzej R., Brown, Karen E., Soza-Ried, Jorge, Feytout, Amelie, Webster, Zoe, Ndjetehe, Elodie, Cantone, Irene, Asenjo, Helena G., Brockdorff, Neil, Carroll, Thomas, Merkenschlager, Matthias, Fisher, Amanda G.

Source: In Cell Reports 28 July 2015 12(4):573-586

The order and logic of CD4 versus CD8 lineage choice and differentiation in mouse thymus

Authors: Karimi, Mohammad M., Guo, Ya, Cui, Xiaokai, Pallikonda, Husayn A., Horková, Veronika, Wang, Yi-Fang, Gil, Sara Ruiz, Rodriguez-Esteban, Gustavo, Robles-Rebollo, Irene, Bruno, Ludovica, Georgieva, Radina, Patel, Bhavik, Elliott, James, Dore, Marian H., Dauphars, Danielle, Krangel, Michael S., Lenhard, Boris, Heyn, Holger, Fisher, Amanda G., Štěpánek, Ondřej, Merkenschlager, Matthias

Source: Nature communications. 12(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191080280.0x000001&indx=1&recIds=ETOCvdc_100191080280.0x000001

Visualizing Changes in Cdkn1c Expression Links Early-Life Adversity to Imprint Mis-regulation in Adults

Authors: Van de Pette, Mathew, Abbas, Allifia, Feytout, Amelie, McNamara, Gráinne, Bruno, Ludovica, To, Wilson K., Dimond, Andrew, Sardini, Alessandro, Webster, Zoe, McGinty, James, Paul, Eleanor J., Ungless, Mark A., French, Paul M.W., Withers, Dominic J., Uren, Anthony, Ferguson-Smith, Anne C., Merkenschlager, Matthias, John, Rosalind M., Fisher, Amanda G.

Source: Cell reports. 18(5):1090-1099

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100062383479.0x000001&indx=1&recIds=ETOCvdc_100062383479.0x000001

Topologically associating domains are ancient features that coincide with Metazoan clusters of extreme noncoding conservation

Authors: Harmston, Nathan, Ing-Simmons, Elizabeth, Tan, Ge, Perry, Malcolm, Merkenschlager, Matthias, Lenhard, Boris

Source: Nature communications. 8(1):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179702117.0x000001&indx=1&recIds=ETOCvdc_100179702117.0x000001

Analysis of Cohesin Function in Gene Regulation and Chromatin Organization in Interphase

Authors: Gupta, Preksha, Lavagnolli, Thais, Mira-Bontenbal, Hegias, Merkenschlager, Matthias

Source: Methods in molecular biology. 1515:197-216

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN608744159&indx=1&recIds=ETOCRN608744159

MicroRNA Targeting of CoREST Controls Polarization of Migrating Cortical Neurons

Authors: Volvert, Marie-Laure, Prévot, Pierre-Paul, Close, Pierre, Laguesse, Sophie, Pirotte, Sophie, Hemphill, James, Rogister, Florence, Kruzy, Nathalie, Sacheli, Rosalie, Moonen, Gustave, Deiters, Alexander, Merkenschlager, Matthias, Chariot, Alain, Malgrange, Brigitte, Godin, Juliette D., Nguyen, Laurent

Source: In Cell Reports 22 May 2014 7(4):1168-1183

MicroRNAs of the miR-290–295 Family Maintain Bivalency in Mouse Embryonic Stem Cells

Authors: Graham, Bryony, Marcais, Antoine, Dharmalingam, Gopuraja, Carroll, Thomas, Kanellopoulou, Chryssa, Graumann, Johannes, Nesterova, Tatyana B., Bermange, Anna, Brazauskas, Pijus, Xella, Barbara, Kriaucionis, Skirmantas, Higgs, Douglas R., Brockdorff, Neil, Mann, Matthias, Fisher, Amanda G., Merkenschlager, Matthias

Source: Stem cell reports. 6(5):635-642

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100063111110.0x000001&indx=1&recIds=ETOCvdc_100063111110.0x000001