Proanthocyanidins alleviate acute alcohol liver injury by inhibiting pyroptosis via inhibiting the ROS-MLKL-CTSB-NLRP3 pathway

Authors: Jin, Yingli ^b, Wang, Chunyun ^b, Meng, Zhuoqun ^a, Zhang, Yuxin ^b, Meng, Desen ^c, Liu, Jiaqi ^c, Yuan, Meng ^c, Guan, Shuang ^{a, ⁎}

Source: In Phytomedicine January 2025 136

Ginsenoside Rb1 alleviates 3-MCPD-induced renal cell pyroptosis by activating mitophagy

Authors: Zhang, Ranran, Guan, Shuang, Meng, Zhuoqun, Zhang, Duoduo, Lu, Jing

Source: In Food and Chemical Toxicology April 2024 186

Apigenin Reduces Lipid Droplet Accumulation in Hepatocytes by Enhancing Chaperone-Mediated Autophagy via AMPK.

Authors: Lu, Jing¹ (AUTHOR), Zhou, Hongjiang¹ (AUTHOR), Hu, Jinping² (AUTHOR), Zhang, Ranran¹ (AUTHOR), Meng, Zhuoqun¹ (AUTHOR), Guan, Shuang^1,3 (AUTHOR) guan_shuang22@jlu.edu.cn

Source: Journal of Agricultural & Food Chemistry. 12/18/2024, Vol. 72 Issue 50, p27965-27977. 13p.

1,3-Dichloro-2-Propanol inhibits autophagy via P53/AMPK/mTOR pathway in HepG2 cells

Authors: Cheng, Bijun, Lu, Jing, Li, Tianjiao, Meng, Zhuoqun, Liu, Meitong, Sun, Maocheng, Guan, Shuang

Source: In Food and Chemical Toxicology December 2018 122:143-150

Alliin attenuates 1, 3-dichloro-2-propanol-induced lipogenesis in HepG2 cells through activation of the AMP-activated protein kinase-dependent pathway

Authors: Lu, Jing, Cheng, Bijun, Meng, Zhuoqun, Fang, Baochen, Li, Tianjiao, Sun, Maocheng, Liu, Meitong, Guan, Shuang

Source: In Life Sciences 15 February 2018 195:19-24

Protective effects of allicin on 1,3-DCP-induced lipid metabolism disorder in HepG2 cells

Authors: Lu, Jing, cheng, Bijun, Fang, Baochen, Meng, Zhuoqun, Zheng, Yiying, Tian, Xiaochen, Guan, Shuang

Source: In Biomedicine & Pharmacotherapy December 2017 96:1411-1417

Apigenin reduces the excessive accumulation of lipids induced by palmitic acid via the AMPK signaling pathway in HepG2 cells.

Authors: Lu, Jing¹ (AUTHOR), Meng, Zhuoqun¹ (AUTHOR), Cheng, Bijun¹ (AUTHOR), Liu, Meitong¹ (AUTHOR), Tao, Siyu² (AUTHOR), Guan, Shuang¹ (AUTHOR) gshuang1973@126.com

Source: Experimental & Therapeutic Medicine. Oct2019, Vol. 18 Issue 4, p2965-2971. 7p.

Subject Terms: *PALMITIC acid, *STEROL regulatory element-binding proteins, *APIGENIN, *LIPIDS, *REDUCTASES, *PROTEIN kinases, *LIPID metabolism

Apigenin Alleviated High-Fat-Diet-Induced Hepatic Pyroptosis by Mitophagy-ROS-CTSB-NLRP3 Pathway in Mice and AML12 Cells.

Authors: Meng, Zhuoqun¹ (AUTHOR), Gao, Min¹ (AUTHOR), Wang, Chunyun² (AUTHOR), Guan, Shuang¹ (AUTHOR), Zhang, DuoDuo³ (AUTHOR) ddzhang@jlu.edu.cn, Lu, Jing¹ (AUTHOR) lu_jing@jlu.edu.cn

Source: Journal of Agricultural & Food Chemistry. 5/10/2023, Vol. 71 Issue 18, p7032-7045. 14p.

Ginsenoside Rb1 induces autophagic lipid degradation via miR-128 targeting TFEB.

Authors: Meng, Zhuoqun, Lu, Jianing, Ge, Guangcai, Wang, Guang, Zhang, Ran, Li, Yuhan, Guan, Shuang, Lu, Jing

Source: Food & Function; 1/7/2023, Vol. 14 Issue 1, p240-249, 10p

1,3‐Dichloro‐2‐propanol induced ferroptosis through Nrf2/ARE signaling pathway in hepatocytes.

Authors: Guan, Shuang, Zhang, Ranran, Zhao, Yanan, Meng, Zhuoqun, Lu, Jing

Source: Environmental Toxicology; Oct2022, Vol. 37 Issue 10, p2515-2528, 14p

Subject Terms: NUCLEAR factor E2 related factor, GLUTAMATE transporters, CELLULAR signal transduction, GLUTATHIONE peroxidase, LIVER cells, HEME oxygenase

Apigenin alleviated PA-induced pyroptosis by activating autophagy in hepatocytes.

Authors: Meng, Zhuoqun, Zhu, Beiwei, Gao, Min, Wang, Guang, Zhou, Hongjiang, Lu, Jing, Guan, Shuang

Source: Food & Function; 5/21/2022, Vol. 13 Issue 10, p5559-5570, 12p

Apigenin induced autophagy and stimulated autophagic lipid degradation.

Authors: Lu, Jing, Meng, Zhuoqun, Chen, Yan, Yu, Liangli, Gao, Boyan, Zheng, Yangjie, Guan, Shuang

Source: Food & Function; Oct2020, Vol. 11 Issue 10, p9208-9215, 8p

Carbon black-benzo(a)pyrene complex-induced apoptosis and autophagy blockage in rat alveolar macrophages.

Authors: Meng, Zhuoqun¹ (AUTHOR), Huang, Yixuan¹ (AUTHOR), Chen, Yan¹ (AUTHOR), Tao, Siyu² (AUTHOR), Liu, Meitong¹ (AUTHOR), Lu, Jing¹ (AUTHOR) lu_jing@jlu.edu.cn, Guan, Shuang¹ (AUTHOR) 907761215@qq.com

Source: Toxicological & Environmental Chemistry. Jan-Apr2020, Vol. 102 Issue 1-4, p132-150. 19p.

Subject Terms: *ALVEOLAR macrophages, *APOPTOSIS, *REACTIVE oxygen species, *POLYCYCLIC aromatic hydrocarbons, *BIOMASS burning