Lessons from Keratin 18 Knockout Mice: Formation of Novel Keratin Filaments, Secondary Loss of Keratin 7 and Accumulation of Liver-Specific Keratin 8-Positive Aggregates

Authors: Magin, Thomas M., Schröder, Rolf, Leitgeb, Sabine, Wanninger, Frederique, Zatloukal, Kurt, Grund, Christine, Melton, David W.

Source: The Journal of Cell Biology, 1998 Mar . 140(6), 1441-1451.

Access URL: https://www.jstor.org/stable/1618538

Gene Targeting at the Mouse Cytokeratin 10 Locus: Severe Skin Fragility and Changes of Cytokeratin Expression in the Epidermis

Authors: Porter, Rebecca M., Leitgeb, Sabine, Melton, David W., Swensson, Ole, Magin, Thomas M.

Source: The Journal of Cell Biology, 1996 Mar 01. 132(5), 925-936.

Access URL: https://www.jstor.org/stable/1617349

Inhibition of the ERCC1–XPF structure-specific endonuclease to overcome cancer chemoresistance

Authors: McNeil, Ewan M., Astell, Katy R., Ritchie, Ann-Marie, Shave, Steven, Houston, Douglas R., Bakrania, Preeti, Jones, Hayley M., Khurana, Puneet, Wallace, Claire, Chapman, Tim, Wear, Martin A., Walkinshaw, Malcolm D., Saxty, Barbara, Melton, David W.

Source: In DNA Repair July 2015 31:19-28

Altered Macrophage Phenotype Transition Impairs Skeletal Muscle Regeneration

Authors: Wang, Hanzhou, Melton, David W., Porter, Laurel, Sarwar, Zaheer U., McManus, Linda M., Shireman, Paula K.

Source: In The American Journal of Pathology April 2014 184(4):1167-1184

Mismatch repair deficiency in ovarian cancer — Molecular characteristics and clinical implications

Authors: Xiao, Xue, Melton, David W., Gourley, Charlie

Source: In Gynecologic Oncology February 2014 132(2):506-512

Temporal phenotypic features distinguish polarized macrophages in vitro

Authors: Melton, David W., McManus, Linda M., Gelfond, Jonathan A. L., Shireman, Paula K.

Source: Autoimmunity. 48(3):161-176

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100097809033.0x000001&indx=1&recIds=ETOCvdc_100097809033.0x000001

Fascin expression is increased in metastatic lesions but does not correlate with progression nor outcome in melanoma

Authors: Ma, Yafeng, Faller, William J., Sansom, Owen J., Brown, Ewan R., Doig, Tamasin N., Melton, David W., Machesky, Laura M.

Source: Melanoma research. 25(2):169-172

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100037070072.0x000001&indx=1&recIds=ETOCvdc_100037070072.0x000001

ALDH2 Mediates 5-Nitrofuran Activity in Multiple Species

Authors: Zhou, Linna, Ishizaki, Hironori, Spitzer, Michaela, Taylor, Kerrie L., Temperley, Nicholas D., Johnson, Stephen L., Brear, Paul, Gautier, Philippe, Zeng, Zhiqiang, Mitchell, Amy, Narayan, Vikram, McNeil, Ewan M., Melton, David W., Smith, Terry K., Tyers, Mike, Westwood, Nicholas J., Patton, E. Elizabeth

Source: In Chemistry & Biology 27 July 2012 19(7):883-892

Association of galectin-3 expression with melanoma progression and prognosis

Authors: Brown, Ewan R., Doig, Tamasin, Anderson, Niall, Brenn, Thomas, Doherty, Val, Xu, Yan, Bartlett, John M.S., Smyth, John F., Melton, David W.

Source: In European Journal of Cancer April 2012 48(6):865-874

Deriving a Boolean dynamics to reveal macrophage activation with in vitro temporal cytokine expression profiles

Authors: Ramirez, Ricardo, Herrera, Allen Michael, Ramirez, Joshua, Qian, Chunjiang, Melton, David W., Shireman, Paula K., Jin, Yu-Fang

Source: BMC bioinformatics. 20(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193399304.0x000001&indx=1&recIds=ETOCvdc_100193399304.0x000001

Mice with DNA repair gene Ercc1 deficiency in a neural crest lineage are a model for late-onset Hirschsprung disease

Authors: Selfridge, Jim, Song, Liang, Brownstein, David G., Melton, David W.

Source: In DNA Repair 2010 9(6):653-660

Topical thymidine dinucleotide application protects against UVB-induced skin cancer in mice with DNA repair gene ( Ercc1)-deficient skin

Authors: Lawrence, Nicola J., Song, Liang, Doig, Jennifer, Ritchie, Ann-Marie, Brownstein, David G., Melton, David W.

Source: In DNA Repair 2009 8(5):664-671

Structure, Expression, and Mutation of the Hypoxanthine Phosphoribosyltransferase Gene

Authors: Melton, David W., Konecki, David S., Brennand, John, Caskey, C. Thomas

Source: Proceedings of the National Academy of Sciences of the United States of America, 1984 Apr 01. 81(7), 2147-2151.

Access URL: https://www.jstor.org/stable/23783

In vitro Translation of Hypoxanthine/Guanine Phosphoribosyltransferase mRNA: Characterization of a Mouse Neuroblastoma Cell Line That Has Elevated Levels of Hypoxanthine/Guanine Phosphoribosyltransferase Protein

Authors: Melton, David W., Konecki, David S., Ledbetter, David H., Hejtmancik, J. Fielding, Caskey, C. Thomas

Source: Proceedings of the National Academy of Sciences of the United States of America, 1981 Nov 01. 78(11), 6977-6980.

Access URL: https://www.jstor.org/stable/11390

Cloned cDNA Sequences of the Hypoxanthine/Guanine Phosphoribosyltransferase Gene from a Mouse Neuroblastoma Cell Line Found to Have Amplified Genomic Sequences

Authors: Brennand, John, Chinault, A. Craig, Konecki, David S., Melton, David W., Caskey, C. Thomas

Source: Proceedings of the National Academy of Sciences of the United States of America, 1982 Mar . 79(6), 1950-1954.

Access URL: https://www.jstor.org/stable/11916

A neurological phenotype in mice with DNA repair gene Ercc1 deficiency

Authors: Lawrence, Nicola J., Sacco, Joseph J., Brownstein, David G., Gillingwater, Thomas H., Melton, David W.

Source: In DNA Repair 2008 7(2):281-291

Characterisation of Ercc1 deficiency in the liver and in conditional Ercc1-deficient primary hepatocytes in vitro

Authors: Kirschner, Kristina, Singh, Rajinder, Prost, Sandrine, Melton, David W.

Source: In DNA Repair 2007 6(3):304-316

Identifying and overcoming a mechanism of resistance to WEE1 kinase inhibitor AZD1775 in high grade serous ovarian cancer cells.

Authors: Gomez, Miriam K., Thomson, John P., Grimes, Graeme R., Wang, Anderson T., Churchman, Michael, O'Connor, Mark J., Gourley, Charlie, Melton, David W.

Source: European Journal of Gynaecological Oncology; 2022, Vol. 43 Issue 2, p183-195, 13p

Subject Terms: OVARIAN cancer, CHECKPOINT kinase 1, DNA damage, WESTERN immunoblotting, RNA sequencing

Male Infertility and DNA Damage in Doppel Knockout and Prion Protein/Doppel Double-Knockout Mice

Authors: Paisley, Derek, Banks, Stephen, Selfridge, Jim, McLennan, Neil F., Ritchie, Ann-Marie, McEwan, Carolanne, Irvine, D. Stewart, Saunders, Philippa T.K., Manson, Jean C., Melton, David W.

Source: In The American Journal of Pathology 2004 164(6):2279-2288

ALDH2 Mediates 5-Nitrofuran Activity in Multiple Species

Authors: Zhou, Linna, Ishizaki, Hironori, Spitzer, Michaela, Taylor, Kerrie L., Temperley, Nicholas D., Johnson, Stephen L., Brear, Paul, Gautier, Philippe, Zeng, Zhiqiang, Mitchell, Amy, Narayan, Vikram, McNeil, Ewan M., Melton, David W., Smith, Terry K., Tyers, Mike, Westwood, Nicholas J., Patton, E. Elizabeth

Source: Cell chemical biology. 27(11):1452-1452

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111290327.0x000001&indx=1&recIds=ETOCvdc_100111290327.0x000001