From Greek paideia to modern educational systems: evidence for the need to integrate physical activity into academic settings

Authors: Oscar Fraile-Martinez, Cielo García-Montero, Marcos Fraile-Martinez, Leonel Pekarek, Silvestra Barrena-Blázquez, Laura López-González, Miguel Angel Álvarez-Mon, Tatiana Pekarek, Carlos Casanova, Melchor Álvarez-Mon, Miguel A. Saez, Raul Diaz, Miguel A. Ortega

Source: Frontiers in Education, Vol 10 (2025)

Subject Terms: paideia, physical education, educational models, body–mind connection, academic performance, Education (General), L7-991

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/feduc.2025.1541876/full; https://doaj.org/toc/2504-284X

Access URL: https://doaj.org/article/74fdc579da0943cb845d58c73ff1228e

Prognostic Value of Histone Acetyl Transferase 1 (HAT-1) and Inflammatory Signatures in Pancreatic Cancer

Authors: Miguel A. Ortega, Laura Jiménez-Álvarez, Oscar Fraile-Martinez, Cielo Garcia-Montero, Luis G. Guijarro, Leonel Pekarek, Silvestra Barrena-Blázquez, Ángel Asúnsolo, Laura López-González, María Del Val Toledo-Lobo, Melchor Álvarez-Mon, Miguel A. Saez, Alberto Gutiérrez-Calvo, Raúl Díaz-Pedrero

Source: Current Issues in Molecular Biology, Vol 46, Iss 5, Pp 3839-3865 (2024)

Subject Terms: pancreatic ductal adenocarcinoma (PDAC), prognostic biomarkers, histone acetyl transferase 1 (HAT-1), interleukin 10 (IL-10), Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1467-3045/46/5/239; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

Access URL: https://doaj.org/article/5acad8944341418cb6d4cb4a72cfade4

Evidence of Inflammatory Network Disruption in Chronic Venous Disease: An Analysis of Circulating Cytokines and Chemokines

Authors: Oscar Fraile-Martinez, Cielo García-Montero, Ana María Gomez-Lahoz, Felipe Sainz, Julia Bujan, Silvestra Barrena-Blázquez, Laura López-González, Raul Díaz-Pedrero, Melchor Álvarez-Mon, Natalio García-Honduvilla, Miguel A. Saez, Jorge Monserrat, Miguel A. Ortega

Source: Biomedicines, Vol 13, Iss 1, p 150 (2025)

Subject Terms: chronic venous disease (CVD), circulating cytokines/chemokines, multiplex, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/13/1/150; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/6b2a7d7d346a4060b500de38c317d5fe

Evolution of the Percutaneous Coronary Intervention (PCI) and Coronary Artery Bypass Grafting (CABG) Indication and Mortality Rates in Spain from 2010 to 2019

Authors: Óscar Gasulla, Antonio Sarría-Santamera, Ferran A. Mazaira-Font, Cielo García-Montero, Oscar Fraile-Martinez, Diego Cantalapiedra, Manuel F. Carrillo-Rodríguez, Belen Gómez-Valcárcel, Miguel Á. Ortega, Melchor Álvarez-Mon, Angel Asúnsolo

Source: Journal of Cardiovascular Development and Disease, Vol 11, Iss 11, p 369 (2024)

Subject Terms: coronary intervention, artery disease, mortality, Spain, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.mdpi.com/2308-3425/11/11/369; https://doaj.org/toc/2308-3425

Access URL: https://doaj.org/article/2e001fddfb5b455bb236471013c2e6d6

A comprehensive study of the academic benefits and practical recommendations to include resistance training programs in institutional education

Authors: Oscar Fraile-Martinez, Cielo García-Montero, Marcos Fraile-Martinez, Leonel Pekarek, Silvestra Barrena-Blázquez, Laura López-González, Miguel Ángel Álvarez-Mon, Tatiana Pekarek, Carlos Casanova, Melchor Álvarez-Mon, Raul Diaz, Miguel A. Saez, Miguel A. Ortega

Source: Frontiers in Psychology, Vol 15 (2024)

Subject Terms: resistance training, academic performance, educational research, physical activity, university, Psychology, BF1-990

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fpsyg.2024.1387162/full; https://doaj.org/toc/1664-1078

Access URL: https://doaj.org/article/3dcf16b3537a4161b4bfef436fdbd38d

Placental Tissue Calcification and Its Molecular Pathways in Female Patients with Late-Onset Preeclampsia

Authors: Miguel A. Ortega, Tatiana Pekarek, Diego De Leon-Oliva, Diego Liviu Boaru, Oscar Fraile-Martinez, Cielo García-Montero, Julia Bujan, Leonel Pekarek, Silvestra Barrena-Blázquez, Raquel Gragera, Patrocinio Rodríguez-Benitez, Mauricio Hernández-Fernández, Laura López-González, Raul Díaz-Pedrero, Ángel Asúnsolo, Melchor Álvarez-Mon, Natalio García-Honduvilla, Miguel A. Saez, Juan A. De León-Luis, Coral Bravo

Source: Biomolecules, Vol 14, Iss 10, p 1237 (2024)

Subject Terms: placenta, late-onset preeclampsia (LO-PE), calcification, placental villi, gene expression, tissue expression, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/14/10/1237; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/047b270adfd14126b62059376843bf42

Abnormal Histopathological Expression of Klotho, Ferroptosis, and Circadian Clock Regulators in Pancreatic Ductal Adenocarcinoma: Prognostic Implications and Correlation Analyses

Authors: Cielo García-Montero, Oscar Fraile-Martinez, David Cobo-Prieto, Diego De Leon-Oliva, Diego Liviu Boaru, Patricia De Castro-Martinez, Leonel Pekarek, Raquel Gragera, Mauricio Hernández-Fernández, Luis G. Guijarro, María Del Val Toledo-Lobo, Laura López-González, Raul Díaz-Pedrero, Jorge Monserrat, Melchor Álvarez-Mon, Miguel A. Saez, Miguel A. Ortega

Source: Biomolecules, Vol 14, Iss 8, p 947 (2024)

Subject Terms: pancreatic ductal adenocarcinoma (PDAC), ferroptosis markers, TFRC, circadian regulators, CLOCK, KLOTHO, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/14/8/947; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/edc7768547bb4297bc788c7a4f6aea07

SARS-CoV-2-Specific T Lymphocytes Analysis in mRNA-Vaccinated Patients with B-Cell Lymphoid Malignancies on Active Treatment

Authors: Patricia García Ramírez, Marta Callejas Charavia, Raquel Oliva Martin, Ana María Gómez La Hoz, Miguel Ángel Ortega, Julio García Suárez, Melchor Álvarez-Mon, Jorge Monserrat Sanz

Source: Vaccines, Vol 12, Iss 9, p 961 (2024)

Subject Terms: vaccine, SARS-CoV-2, antibodies, CD4+ and CD8+ T lymphocytes, B-cell lymphoid malignancy, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/12/9/961; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/2f699127fad34f4b904b6365be6e7e9c

News in pharmacology for the main medical pathologies of gestation

Authors: María De Guadalupe Quintana-Coronado, Coral Bravo, Melchor Álvarez-Mon, Miguel A. Ortega, Juan A. De León-Luis

Source: Frontiers in Pharmacology, Vol 14 (2024)

Subject Terms: pharmacology, pregnancy complications, analgesia, antibiotic therapy, fetal maternal well-being, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1240032/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/2c398b5ac14f43398d1eae21ee4ffd08

Post-COVID-19 condition in pregnant and postpartum women: a long-term follow-up, observational prospective studyResearch in context

Authors: Mar Muñoz-Chápuli Gutiérrez, Ainoa Sáez Prat, Ana Durán Vila, Mireia Bernal Claverol, Pilar Payá Martínez, Pilar Pintado Recarte, Mamen Viñuela Benéitez, Cristina Ausín García, Eva Cervilla Muñoz, Marisa Navarro, Pablo González Navarro, Melchor Álvarez-Mon, Miguel A. Ortega, Juan de León-Luís

Source: EClinicalMedicine, Vol 67, Iss , Pp 102398- (2024)

Subject Terms: Post-COVID-19, Long COVID, Pregnancy, Postpartum, Perinatal, COVID-19, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589537023005758; https://doaj.org/toc/2589-5370

Access URL: https://doaj.org/article/381ac2e8c312451195574e89c318ae62

A comprehensive look at the psychoneuroimmunoendocrinology of spinal cord injury and its progression: mechanisms and clinical opportunities

Authors: Miguel A. Ortega, Oscar Fraile-Martinez, Cielo García-Montero, Sergio Haro, Miguel Ángel Álvarez-Mon, Diego De Leon-Oliva, Ana M. Gomez-Lahoz, Jorge Monserrat, Mar Atienza-Pérez, David Díaz, Elisa Lopez-Dolado, Melchor Álvarez-Mon

Source: Military Medical Research, Vol 10, Iss 1, Pp 1-40 (2023)

Subject Terms: Spinal cord injury (SCI), Psychoneuroimmunoendocrinology (PNIE), Secondary injury, Immunoinflammatory dysfunction, Gut microbiota, Translational opportunities, Medicine (General), R5-920, Military Science

File Description: electronic resource

Relation: https://doaj.org/toc/2054-9369

Access URL: https://doaj.org/article/e2b2e426285f418aa918d12c484bed62

Oxidative Stress, Lipid Peroxidation and Ferroptosis Are Major Pathophysiological Signatures in the Placental Tissue of Women with Late-Onset Preeclampsia

Authors: Miguel A. Ortega, Luis M. Garcia-Puente, Oscar Fraile-Martinez, Tatiana Pekarek, Cielo García-Montero, Julia Bujan, Leonel Pekarek, Silvestra Barrena-Blázquez, Raquel Gragera, Inmaculada C. Rodríguez-Rojo, Patrocinio Rodríguez-Benitez, Laura López-González, Raul Díaz-Pedrero, Melchor Álvarez-Mon, Natalio García-Honduvilla, Juan A. De León-Luis, Coral Bravo, Miguel A. Saez

Source: Antioxidants, Vol 13, Iss 5, p 591 (2024)

Subject Terms: oxidative stress, lipid peroxidation, ferroptosis, placental, preeclampsia, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/13/5/591; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/c21a94729f5d4519b480b45020075cd6

Vascular Calcification: Molecular Networking, Pathological Implications and Translational Opportunities

Authors: Miguel A. Ortega, Diego De Leon-Oliva, Maria José Gimeno-Longas, Diego Liviu Boaru, Oscar Fraile-Martinez, Cielo García-Montero, Amador Velazquez de Castro, Silvestra Barrena-Blázquez, Laura López-González, Silvia Amor, Natalio García-Honduvilla, Julia Buján, Luis G. Guijarro, Elisa Castillo-Ruiz, Miguel Ángel Álvarez-Mon, Agustin Albillos, Melchor Álvarez-Mon, Raul Diaz, Miguel A. Saez

Source: Biomolecules, Vol 14, Iss 3, p 275 (2024)

Subject Terms: vascular calcification, signaling pathways, endothelial cells (ECs), vascular smooth muscle cells (VSMCs), biomarkers, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/14/3/275; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/7fe548b13c4042d5be8b93ca93aa3728

Enhancing physicians’ radiology diagnostics of COVID-19’s effects on lung health by leveraging artificial intelligence

Authors: Óscar Gasulla, Maria J. Ledesma-Carbayo, Luisa N. Borrell, Jordi Fortuny-Profitós, Ferran A. Mazaira-Font, Jose María Barbero Allende, David Alonso-Menchén, Josep García-Bennett, Belen Del Río-Carrrero, Hector Jofré-Grimaldo, Aleix Seguí, Jorge Monserrat, Miguel Teixidó-Román, Adrià Torrent, Miguel Ángel Ortega, Melchor Álvarez-Mon, Angel Asúnsolo

Source: Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)

Subject Terms: radiology diagnostics, COVID-19, ICU, lung area, artificial intelligence, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fbioe.2023.1010679/full; https://doaj.org/toc/2296-4185

Access URL: https://doaj.org/article/8b0efd4064424f829a311aca017ba62d

Placentas from Women with Late-Onset Preeclampsia Exhibit Increased Expression of the NLRP3 Inflammasome Machinery

Authors: Luis M. Garcia-Puente, Oscar Fraile-Martinez, Cielo García-Montero, Julia Bujan, Juan A. De León-Luis, Coral Bravo, Patrocinio Rodríguez-Benitez, Pilar Pintado, Francisco Javier Ruiz-Labarta, Melchor Álvarez-Mon, Natalio García-Honduvilla, María J. Cancelo, Miguel A. Saez, Miguel A. Ortega

Source: Biomolecules, Vol 13, Iss 11, p 1644 (2023)

Subject Terms: placenta, late-onset pre-eclampsia (LO-PE), NLRP3 inflammasome, caspases, interleukin 1β, interleukin 18, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/13/11/1644; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/e8d03bc098e44a13ac32b66f6564ee33

Advanced Hydrogel-Based Strategies for Enhanced Bone and Cartilage Regeneration: A Comprehensive Review

Authors: Diego De Leon-Oliva, Diego Liviu Boaru, Roque Emilio Perez-Exposito, Oscar Fraile-Martinez, Cielo García-Montero, Raul Diaz, Julia Bujan, Natalio García-Honduvilla, Laura Lopez-Gonzalez, Melchor Álvarez-Mon, Jose V. Saz, Basilio de la Torre, Miguel A. Ortega

Source: Gels, Vol 9, Iss 11, p 885 (2023)

Subject Terms: tissue engineering and regenerative medicine (TERM), advanced hydrogels, bone regeneration, extracellular matrix (ECM), scaffolds, stem cells (SCs), Science, Chemistry, QD1-999, Inorganic chemistry, QD146-197, General. Including alchemy, QD1-65

File Description: electronic resource

Relation: https://www.mdpi.com/2310-2861/9/11/885; https://doaj.org/toc/2310-2861

Access URL: https://doaj.org/article/9223c76ebc0f4ac29eda5d6fa990ec3d

Exploring the Role of Mediterranean and Westernized Diets and Their Main Nutrients in the Modulation of Oxidative Stress in the Placenta: A Narrative Review

Authors: Cielo García-Montero, Oscar Fraile-Martinez, Diego De Leon-Oliva, Diego Liviu Boaru, Luis M. Garcia-Puente, Juan A. De León-Luis, Coral Bravo, Raul Diaz-Pedrero, Laura Lopez-Gonzalez, Melchor Álvarez-Mon, Natalio García-Honduvilla, Miguel A. Saez, Miguel A. Ortega

Source: Antioxidants, Vol 12, Iss 11, p 1918 (2023)

Subject Terms: oxidative stress, placenta, pregnancy, Mediterranean diet, Western diet, high-fat diet, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/12/11/1918; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/6ad23ee4b88e4afe98fb8eb6a9952795

The RANK–RANKL–OPG System: A Multifaceted Regulator of Homeostasis, Immunity, and Cancer

Authors: Diego De Leon-Oliva, Silvestra Barrena-Blázquez, Laura Jiménez-Álvarez, Oscar Fraile-Martinez, Cielo García-Montero, Laura López-González, Diego Torres-Carranza, Luis M. García-Puente, Sara T. Carranza, Miguel Ángel Álvarez-Mon, Melchor Álvarez-Mon, Raul Diaz, Miguel A. Ortega

Source: Medicina, Vol 59, Iss 10, p 1752 (2023)

Subject Terms: RANKL, RANK, osteoclast, immune system, bone metastasis, breast cancer, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/1648-9144/59/10/1752; https://doaj.org/toc/1010-660X; https://doaj.org/toc/1648-9144

Access URL: https://doaj.org/article/649fdbfef5ce4cf1928b36f78f5c4420

Unraveling the New Perspectives on Antimicrobial Hydrogels: State-of-the-Art and Translational Applications

Authors: Miguel A. Ortega, Diego De Leon-Oliva, Diego Liviu Boaru, Oscar Fraile-Martinez, Cielo García-Montero, Raul Diaz, Santiago Coca, Silvestra Barrena-Blázquez, Julia Bujan, Natalio García-Honduvilla, Miguel A. Saez, Melchor Álvarez-Mon, Jose V. Saz

Source: Gels, Vol 9, Iss 8, p 617 (2023)

Subject Terms: antimicrobial gels, antibiotics, drug delivery, wound healing, tissue regeneration, Science, Chemistry, QD1-999, Inorganic chemistry, QD146-197, General. Including alchemy, QD1-65

File Description: electronic resource

Relation: https://www.mdpi.com/2310-2861/9/8/617; https://doaj.org/toc/2310-2861

Access URL: https://doaj.org/article/8cec95b974f54addb773002db53861a2

Abnormal Characterization and Distribution of Circulating Regulatory T Cells in Patients with Chronic Spinal Cord Injury According to the Period of Evolution

Authors: Ana M. Gómez-Lahoz, Sergio Haro Girón, Jorge Monserrat Sanz, Oscar Fraile-Martínez, Cielo Garcia-Montero, Diego J. Jiménez, Diego de Leon-Oliva, Miguel A. Ortega, Mar Atienza-Perez, David Diaz, Elisa Lopez-Dolado, Melchor Álvarez-Mon

Source: Biology, Vol 12, Iss 4, p 617 (2023)

Subject Terms: chronic spinal cord injury (SCI), regulatory T cells (Treg), period of evolution, immune dysfunction, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2079-7737/12/4/617; https://doaj.org/toc/2079-7737

Access URL: https://doaj.org/article/0b1d50a24cdd491ba32e41d77141b02d