Transcriptomic profile of RNA pseudouridine modification as a biomarker for cellular senescence associated with survival outcomes in colorectal cancer

Authors: Yingguo Gan, Ze Yuan, Jingrong Weng, Mingzhe Huang, Tuoyang Li, Yuanhui Wu, Kaixin Lin, Junyi Han, Xuan Li, Haotian Liu, Zixiao Wan, Ziming Li, Zhenghua Chen, Ji Cui, Yanxin Luo, Meijin Huang, Huichuan Yu, Jinxin Lin

Source: BMC Biology, Vol 23, Iss 1, Pp 1-18 (2025)

Subject Terms: RNA Ψ modification, Cellular senescence, Colorectal cancer, Psi Score, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7007

Access URL: https://doaj.org/article/ccdc83a126e64d87be58c7e495f4ed33

Spatial deconvolution from bulk DNA methylation profiles determines intratumoral epigenetic heterogeneity

Authors: Binbin Liu, Yumo Xie, Yu Zhang, Guannan Tang, Jinxin Lin, Ze Yuan, Xiaoxia Liu, Xiaolin Wang, Meijin Huang, Yanxin Luo, Huichuan Yu

Source: Cell & Bioscience, Vol 15, Iss 1, Pp 1-16 (2025)

Subject Terms: DNA methylation, Intratumor heterogeneity, Epigenetic, Colorectal cancer, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/2045-3701

Access URL: https://doaj.org/article/758f3523dda645f2bd2161882863187d

Disrupting EDEM3‐induced M2‐like macrophage trafficking by glucose restriction overcomes resistance to PD‐1/PD‐L1 blockade

Authors: Shaoyong Peng, Minshan Wu, Qian Yan, Gaopo Xu, Yumo Xie, Guannan Tang, Jinxin Lin, Zixu Yuan, Xiaoxia Liang, Ze Yuan, Jingrong Weng, Liangliang Bai, Xiaolin Wang, Huichuan Yu, Meijin Huang, Yanxin Luo, Xiaoxia Liu

Source: Clinical and Translational Medicine, Vol 15, Iss 1, Pp n/a-n/a (2025)

Subject Terms: 2‐DG, antitumour immunity, cancer‐associated fibroblasts, fasting‐mimicking diet, glycosyltransferase EDEM3, M2‐like macrophage, Medicine (General), R5-920

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Relation: https://doaj.org/toc/2001-1326

Access URL: https://doaj.org/article/eb5c571e1c8c4a04b38a5ff93362f5e7

Rituximab-associated adverse events in nephrotic syndrome: A systematic review and meta-analysis

Authors: Zixian Yu, Meijin Huang, Yunlong Qin, Xiayin Li, Yueru Zhao, Yuwei Wang, Yumeng Zhang, Anjing Wang, Mei Han, Jin Zhao, Shiren Sun

Source: Heliyon, Vol 11, Iss 1, Pp e41212- (2025)

Subject Terms: Rituximab, Nephrotic syndrome, Adverse events, Systematic review, Meta-analysis, Science (General), Q1-390, Social sciences (General), H1-99

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Relation: http://www.sciencedirect.com/science/article/pii/S240584402417243X; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/e3ec69ed2c6c44378c434f1efa3253ec

Radiogenomic profiling of global DNA methylation associated with molecular phenotypes and immune features in glioma

Authors: Zhuokai Zhuang, Jinxin Lin, Zixiao Wan, Jingrong Weng, Ze Yuan, Yumo Xie, Zongchao Liu, Peiyi Xie, Siyue Mao, Zongming Wang, Xiaolin Wang, Meijin Huang, Yanxin Luo, Huichuan Yu

Source: BMC Medicine, Vol 22, Iss 1, Pp 1-13 (2024)

Subject Terms: Radiogenomics, Molecular characterization, DNA methylation, Magnetic resonance imaging, Medicine

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Relation: https://doaj.org/toc/1741-7015

Access URL: https://doaj.org/article/f55e31d92a884c60a69b28a048c57258

Gamma-glutamyl transferase to aspartate aminotransferase ratio (GSR) predicts prognoses in patients with colorectal cancer with liver metastasis after microwave ablation

Authors: Mingzhe Huang, Zhiliang Chen, Si Qin, Jiaming Zhou, Yan Huang, Shaoyong Peng, Pinzhu Huang, Yi Lin, Maram Alenzi, Jun Huang, Jing Lin, Zhiyong Chen, Meijin Huang, Guangjian Liu

Source: BMC Gastroenterology, Vol 24, Iss 1, Pp 1-11 (2024)

Subject Terms: Colorectal cancer, Liver metastasis, Microwave ablation, Gamma-glutamyl transpeptidase, Aspartate aminotransferase, Diseases of the digestive system. Gastroenterology, RC799-869

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Relation: https://doaj.org/toc/1471-230X

Access URL: https://doaj.org/article/c1f2b8e7ec7a4209813b0560bfa1515e

Preservation versus resection of Denonvilliers’ fascia in total mesorectal excision for male rectal cancer: follow-up analysis of the randomized PUF-01 trial

Authors: Jiafeng Fang, Bo Wei, Zongheng Zheng, Jian’an Xiao, Fanghai Han, Meijin Huang, Qingwen Xu, Xiaozhong Wang, Chuyuan Hong, Gongping Wang, Yongle Ju, Guoqiang Su, Haijun Deng, Jinxin Zhang, Jun Li, Xiaofeng Yang, Tufeng Chen, Yong Huang, Jianglong Huang, Jianpei Liu, Hongbo Wei, Chinese Postoperative Urogenital Function (PUF) Research Collaboration Group

Source: Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/373aa72bba014792afcc8fb94bb6e67e

PD‐1 blockade enhances the effect of targeted chemotherapy on locally advanced pMMR/MSS colorectal cancer

Authors: Fengyun Pei, Wan He, Yinghua Duan, Qijun Yao, Yandong Zhao, Xinjuan Fan, Shuai Liu, Haiyang Chen, Fang He, Tingzhi Liu, Jiaoting Chen, Yijia Zheng, Heping Li, Xiaofang Guo, Lishuo Shi, Li Ling, Yaoxu Chen, Jiapeng He, Miao Liu, Mengli Huang, Yuezong Bai, Jianping Wang, Meijin Huang, Jun Huang

Source: Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)

Subject Terms: colorectal cancer, neoadjuvant treatment, PD‐1 blockade, pMMR/MSS, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

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Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/478e2f55036f4d94b5bcf65305acb66a

CagA-positive Helicobacter pylori may promote and aggravate scrub typhus

Authors: Qiuying Du, Houyang Zeng, Xianwu Pang, Jianyu Cao, Bo Xie, Chunyi Long, Liudan Liang, Fenglian Deng, Meijin Huang, Li Li, Fengyan Huang, Xinli Liu, Yanling Hu, Jiannan Lv

Source: Frontiers in Microbiology, Vol 15 (2024)

Subject Terms: Helicobacter pylori, scrub typhus, Th1 immune response, CagA gene, Orientia tsutsugamushi, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2024.1351784/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/a8602f51859d414592e6d53f0db19d2e

Radiological lymph‐node size improves the prognostic value of systemic inflammation index in rectal cancer with pathologically negative nodes

Authors: Shaoyong Peng, Xiaoxia Liu, Yingjie Li, Huichuan Yu, Yumo Xie, Xiaolin Wang, Jiaming Zhou, Mingxuan Zhu, Yanxin Luo, Meijin Huang

Source: Cancer Medicine, Vol 12, Iss 9, Pp 10303-10314 (2023)

Subject Terms: NLR, node‐negative rectal cancer, radiological lymph node, survival outcome, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/250841e912c64ee4bdba623c46a49e8b

Aberrant methylation in neurofunctional gene serves as a hallmark of tumorigenesis and progression in colorectal cancer

Authors: Xuan Li, Du Cai, Yaoyi Huang, Yumo Xie, Dingcheng Shen, Ze Yuan, Xiaoxia Liu, Meijin Huang, Yanxin Luo, Huichuan Yu, Xiaolin Wang

Source: BMC Cancer, Vol 23, Iss 1, Pp 1-11 (2023)

Subject Terms: Colorectal cancer, DNA methylation, Prognosis, Biomarker, RIMS2, KRAS, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

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Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/2d0a194b15e741b28d6ae314eef1ca9e

Clinical spectrum of rectal cancer identifies hallmarks of early‐onset patients and next‐generation treatment strategies

Authors: Dingcheng Shen, Puning Wang, Yumo Xie, Zhuokai Zhuang, Mingxuan Zhu, Xiaolin Wang, Meijin Huang, Yanxin Luo, Huichuan Yu

Source: Cancer Medicine, Vol 12, Iss 3, Pp 3433-3441 (2023)

Subject Terms: cancer treatment, clinicopathological features, early‐onset, rectal cancer, young, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

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Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/1685ce8406054de1aa3880411e45ab34

RNA demethylase ALKBH5 promotes colorectal cancer progression by posttranscriptional activation of RAB5A in an m6A‐YTHDF2‐dependent manner

Authors: Dingcheng Shen, Jinxin Lin, Yumo Xie, Zhuokai Zhuang, Gaopo Xu, Shaoyong Peng, Guannan Tang, Liangliang Bai, Mingxuan Zhu, Yu Zhang, Ziying Huang, Puning Wang, Xiaoxia Liu, Meijin Huang, Yanxin Luo, Xiaolin Wang, Huichuan Yu

Source: Clinical and Translational Medicine, Vol 13, Iss 5, Pp n/a-n/a (2023)

Subject Terms: ALKBH5, colorectal cancer (CRC), N6‐methyladenosine (m6A), RAB5A, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2001-1326

Access URL: https://doaj.org/article/27155b25e31349d6a242d8514f8c0397

Clinical atlas of rectal cancer highlights the barriers and insufficient interventions underlying the unfavorable outcomes in older patients

Authors: Zhuoyang Zhao, Jinxin Lin, Shunlun Chen, Xiaolin Wang, Heng Wang, Gaopo Xu, Jianru Wang, Ruwen Zhou, Zenghong Huang, Yingjie Li, Yu Zhang, Xiaoxia Liu, Puning Wang, Meijin Huang, Yanxin Luo, Huichuan Yu

Source: Heliyon, Vol 9, Iss 5, Pp e15966- (2023)

Subject Terms: Old patients, Rectal cancer, Cancer care, Aging, Nutrition, Comorbidity, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844023031730; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/f922fd87d375427d9c30326ced0e601a

Fasting-mimicking diet synergizes with ferroptosis against quiescent, chemotherapy-resistant cellsResearch in context

Authors: Xiaoxia Liu, Shaoyong Peng, Guannan Tang, Gaopo Xu, Yumo Xie, Dingcheng Shen, Mingxuan Zhu, Yaoyi Huang, Xiaolin Wang, Huichuan Yu, Meijin Huang, Yanxin Luo

Source: EBioMedicine, Vol 90, Iss , Pp 104496- (2023)

Subject Terms: Colorectal cancer, Fasting, Quiescent cells, Ferroptosis, Drug-tolerant persister cells, Autophagy, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396423000610; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/d9416ecce023430da00d0fa93857aef4

PROS1 shapes the immune-suppressive tumor microenvironment and predicts poor prognosis in glioma

Authors: Jinxiang Wang, Nisha Wu, Xiaowei Feng, Yanling Liang, Meijin Huang, Wenle Li, Lingmi Hou, Chengliang Yin

Source: Frontiers in Immunology, Vol 13 (2023)

Subject Terms: PROS1, exhausted T cell, biomarker, glioma immunosuppressive microenvironment, prognosis, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1052692/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/c5f9d7eaeb374902bca7cd7d464e3955

Current treatment and surveillance modalities are not sufficient for advanced stage III colon cancer: Result from a multicenter cohort analysis

Authors: Juan Li, Yumo Xie, Ziying Huang, Dingcheng Shen, Zhuokai Zhuang, Mingxuan Zhu, Yaoyi Huang, Rongzhao He, Xiaolin Wang, Meijin Huang, Yanxin Luo, Huichuan Yu

Source: Cancer Medicine, Vol 10, Iss 24, Pp 8924-8933 (2021)

Subject Terms: advanced stage, colorectal cancer, management, SEER, survival, treatment, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/bef7f7f1e752494fbba4495b7170dc19

Silence of a dependence receptor CSF1R in colorectal cancer cells activates tumor-associated macrophages

Authors: Rui Ma, Ping Yuan, Xiaolin Wang, Yingjie Li, Meijin Huang, Huichuan Yu, Yanxin Luo, Mingxuan Zhu, Liangliang Bai, Xiaoxia Liu, Shaoyong Peng, Yumo Xie, Hong Bai, Jinxin Lin, Linping Wu

Source: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/10/12/e005610.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/4f55d7bbb7c54ab7b085143a3b1b7b8b

Radiomic signature of the FOWARC trial predicts pathological response to neoadjuvant treatment in rectal cancer

Authors: Zhuokai Zhuang, Zongchao Liu, Juan Li, Xiaolin Wang, Peiyi Xie, Fei Xiong, Jiancong Hu, Xiaochun Meng, Meijin Huang, Yanhong Deng, Ping Lan, Huichuan Yu, Yanxin Luo

Source: Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-10 (2021)

Subject Terms: Radiomics, Computed tomography, Neoadjuvant treatment, Rectal cancer, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/eb3bb4b4d48c49908fd31fb0da285a79

Genome-wide analysis identifies critical DNA methylations within NTRKs genes in colorectal cancer

Authors: Zijian Chen, Zenghong Huang, Yanxin Luo, Qi Zou, Liangliang Bai, Guannan Tang, Xiaolin Wang, Guangwen Cao, Meijin Huang, Jun Xiang, Huichuan Yu

Source: Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-13 (2021)

Subject Terms: NTRKs, NTRK3, Methylation, Colorectal cancer, Prognosis, Medicine

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Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/6a03d7c9cf0b42cc9ad766d06335287a