Dasatinib interferes with HIV-1 proviral integration and the inflammatory potential of monocyte-derived macrophages from people with HIV

Authors: Rodríguez-Mora, Sara, Sánchez-Menéndez, Clara, Bautista-Carrascosa, Guiomar, Mateos, Elena, Moreno-Serna, Lucia, Megías, Diego, Cantón, Juan, García-Gutiérrez, Valentín, Murciano-Antón, María Aránzazu, Cervero, Miguel, Spivak, Adam, Planelles, Vicente, Coiras, Mayte

Source: In Biochemical Pharmacology November 2024 229

PP2A-B55 phosphatase counteracts Ki-67-dependent chromosome individualization during mitosis

Authors: Sanz-Flores, María, Ruiz-Torres, Miguel, Aguirre-Portolés, Cristina, El Bakkali, Aicha, Salvador-Barberó, Beatriz, Villarroya-Beltri, Carolina, Ortega, Sagrario, Megías, Diego, Gerlich, Daniel W., Álvarez-Fernández, Mónica, Malumbres, Marcos

Source: In Cell Reports 23 July 2024 43(7)

Nano-Sized Liposomes for Click-Chemistry-Based Selective Guiding of Immune Cells to Neuroblastoma.

Authors: Arroyo-Nogales, Alicia, Jimenez-Falcao, Sandra, Megias, Diego, Ramirez, Manuel, Baeza, Alejandro

Source: ACS Applied Nano Materials; 2/28/2025, Vol. 8 Issue 8, p4229-4239, 11p

Liposomal-Based Nanoarchitectonics as Bispecific T Cell Engagers in Neuroblastoma Therapy.

Authors: Parra-Nieto, Jorge, Hidalgo, Laura, Márquez-Cantudo, Marta, García-Castro, Javier, Megias, Diego, Ramirez, Manuel, Baeza, Alejandro

Source: ACS Applied Materials & Interfaces; 2/26/2025, Vol. 17 Issue 8, p11937-11945, 9p

Assessing kinetics and recruitment of DNA repair factors using high content screens

Authors: Martinez-Pastor, Barbara, Silveira, Giorgia G., Clarke, Thomas L., Chung, Dudley, Gu, Yuchao, Cosentino, Claudia, Davidow, Lance S., Mata, Gadea, Hassanieh, Sylvana, Salsman, Jayme, Ciccia, Alberto, Bae, Narkhyun, Bedford, Mark T., Megias, Diego, Rubin, Lee L., Efeyan, Alejo, Dellaire, Graham, Mostoslavsky, Raul

Source: In Cell Reports 28 December 2021 37(13)

Telomerase therapy attenuates cardiotoxic effects of doxorubicin

Authors: Chatterjee, Shambhabi, Hofer, Teresa, Costa, Alessia, Lu, Dongchao, Batkai, Sandor, Gupta, Shashi Kumar, Bolesani, Emiliano, Zweigerdt, Robert, Megias, Diego, Streckfuss-Bömeke, Katrin, Brandenberger, Christina, Thum, Thomas, Bär, Christian

Source: In Molecular Therapy 7 April 2021 29(4):1395-1410

Dual-pore protocells with multitasking capacities for simultaneous delivery of therapeutic enzymes and drugs in macrophage depletion therapy.

Authors: Parra-Nieto, Jorge, Arroyo-Nogales, Alicia, Marcos-Fernández, Diana, Jimenez-Falcao, Sandra, Arribas, Carmen, Megias, Diego, Gonzalez-Murillo, África, Ramirez, Manuel, Baeza, Alejandro

Source: Biomaterials Science (2047-4830); 10/21/2024, Vol. 12 Issue 20, p5372-5385, 14p

Multifunctional Nanoassemblies for Cytotoxic Drug and Therapeutic Enzymes Delivery in Neuroblastoma Therapy

Authors: Parra‐Nieto, Jorge, García del Cid, María Amor, Galeano, Carolina, Carcer, Iñigo Aguirre, García‐García, Lorena, Gonzalez‐Murillo, África, Megias, Diego, Ramirez, Manuel, Baeza, Alejandro

Source: Advanced materials interfaces. 10(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100172973103.0x000001&indx=1&recIds=ETOCvdc_100172973103.0x000001

PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection

Authors: Morales, Carmen, Ruiz-Torres, Miguel, Rodríguez-Acebes, Sara, Lafarga, Vanesa, Rodríguez-Corsino, Miriam, Megías, Diego, Cisneros, David A. ^**, Peters, Jan-Michael ^**, Méndez, Juan, Losada, Ana

Source: In Journal of Biological Chemistry 3 January 2020 295(1):146-157

Safety of Whole-Body Abrogation of the TRF1 Shelterin Protein in Wild-Type and Cancer-Prone Mouse Models

Authors: Bejarano, Leire, Louzame, Jessica, Montero, Juán José, Megías, Diego, Flores, Juana M., Blasco, Maria A.

Source: In iScience 27 September 2019 19:572-585

Screening protocol for the identification of modulators by immunofluorescent cell‐based assay

Authors: Klett, Javier, Gómez‐Casero, Elena, Méndez‐Pertuz, Marinela, Urbano‐Cuadrado, Manuel, Megias, Diego, Blasco, María A., Martínez, Sonia, Pastor, Joaquín, Blanco‐Aparicio, Carmen

Source: Chemical biology & drug design. 95(1):66-78

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100095982335.0x000001&indx=1&recIds=ETOCvdc_100095982335.0x000001

HCS Methodology for Helping in Lab Scale Image-Based Assays

Authors: Soriano, Joaquim, Mata, Gadea, Megias, Diego

Source: Methods in molecular biology. 2040:331-358

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN621339823&indx=1&recIds=ETOCRN621339823

High-Throughput Image-Based Screening to Identify Chemical Compounds Capable of Activating FOXO

Authors: Barradas, Marta, Link, Wolfgang, Megias, Diego, Fernandez-Marcos, Pablo J.

Source: Methods in molecular biology. 1890:151-162

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN618257460&indx=1&recIds=ETOCRN618257460

Lysosomal trapping of palbociclib and its functional implications

Authors: Llanos, Susana, Megias, Diego, Blanco-Aparicio, Carmen, Hernández-Encinas, Elena, Rovira, Miguel, Pietrocola, Federico, Serrano, Manuel

Source: Oncogene. 38(20):3886-3902

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140050190.0x000001&indx=1&recIds=ETOCvdc_100140050190.0x000001

Inhibition of TRF1 Telomere Protein Impairs Tumor Initiation and Progression in Glioblastoma Mouse Models and Patient-Derived Xenografts

Authors: Bejarano, Leire, Schuhmacher, Alberto J., Méndez, Marinela, Megías, Diego, Blanco-Aparicio, Carmen, Martínez, Sonia, Pastor, Joaquín, Squatrito, Massimo, Blasco, Maria A.

Source: In Cancer Cell 13 November 2017 32(5):590-607

Application of standard cell cultures and 3D in vitro tissue models as an effective tool in drug design and development

Authors: Amelian, Aleksandra, Wasilewska, Katarzyna, Megias, Diego, Winnicka, Katarzyna

Source: In Pharmacological Reports October 2017 69(5):861-870

Common Telomere Changes during In Vivo Reprogramming and Early Stages of Tumorigenesis

Authors: Marión, Rosa M., López de Silanes, Isabel, Mosteiro, Lluc, Gamache, Benjamin, Abad, María, Guerra, Carmen, Megías, Diego, Serrano, Manuel, Blasco, Maria A.

Source: In Stem Cell Reports 14 February 2017 8(2):460-475

Regulation of OGT by URI in Response to Glucose Confers c-MYC-Dependent Survival Mechanisms

Authors: Burén, Stefan, Gomes, Ana L., Teijeiro, Ana, Fawal, Mohamad-Ali, Yilmaz, Mahmut, Tummala, Krishna S., Perez, Manuel, Rodriguez-Justo, Manuel, Campos-Olivas, Ramón, Megías, Diego, Djouder, Nabil

Source: In Cancer Cell 8 August 2016 30(2):290-307

Monitoring vascular normalization induced by antiangiogenic treatment with 18F-fluoromisonidazole-PET

Authors: Hernández-Agudo, Elena, Mondejar, Tamara, Soto-Montenegro, Maria Luisa, Megías, Diego, Mouron, Silvana, Sanchez, Jesus, Hidalgo, Manuel, Lopez-Casas, Pedro Pablo, Mulero, Francisca, Desco, Manuel, Quintela-Fandino, Miguel

Source: In Molecular Oncology May 2016 10(5):704-718

Proteomic Analysis of Connexin 43 Reveals Novel Interactors Related to Osteoarthritis

Authors: Gago-Fuentes, Raquel ^‡, Fernández-Puente, Patricia ^{§, ¶}, Megias, Diego ^‖, Carpintero-Fernández, Paula ^‡, Mateos, Jesus ^{§, ¶}, Acea, Benigno ^‡, Fonseca, Eduardo ^‡, Blanco, Francisco Javier ^{§, ¶}, Mayan, Maria Dolores ^{‡, **}

Source: In Molecular & Cellular Proteomics July 2015 14(7):1831-1845