Multi-ancestry genome-wide association analyses: a comparison of meta- and mega-analyses in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study

Authors: Alan Kuang, Marie-France Hivert, M. Geoffrey Hayes, William L. Lowe, Denise M. Scholtens

Source: BMC Genomics, Vol 26, Iss 1, Pp 1-15 (2025)

Subject Terms: Genome-wide association analysis, Multi-ancestry, Meta-analysis, Mega-analysis, Biotechnology, TP248.13-248.65, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2164

Access URL: https://doaj.org/article/e83a191c059641f990cd9e04f44326db

Bridging big data in the ENIGMA consortium to combine non-equivalent cognitive measures

Authors: Eamonn Kennedy, Shashank Vadlamani, Hannah M. Lindsey, Pui-Wa Lei, Mary Jo-Pugh, Paul M. Thompson, David F. Tate, Frank G. Hillary, Emily L. Dennis, Elisabeth A. Wilde, for the ENIGMA Clinical Endpoints Working Group

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)

Subject Terms: Harmonization, Verbal learning, Mega analysis, Traumatic brain injury, Item response theory, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/fb501d249bbd4b50bbbbb5ced8d8df78

Disentangling emotional source memory: a mega-analysis on the effects of emotion on item-context binding in episodic long-term memory

Authors: Carlos Ventura-Bort, Yuta Katsumi, Janine Wirkner, Julia Wendt, Lars Schwabe, Alfons O. Hamm, Florin Dolcos, Mathias Weymar

Source: Frontiers in Psychology, Vol 15 (2024)

Subject Terms: emotion, episodic memory, long-term memory, source memory, mega-analysis, Psychology, BF1-990

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fpsyg.2024.1459617/full; https://doaj.org/toc/1664-1078

Access URL: https://doaj.org/article/0a0472f9906048cdbfec5a43fda8ff34

Genome-Wide Association Study Based on Mega-Analysis to Detect Genomic Regions Associated with Prolificacy in Sheep

Authors: Hossein Mohammadi

Source: پژوهشهای علوم دامی ایران, Vol 16, Iss 2, Pp 249-258 (2024)

Subject Terms: association analysis, genomic region, genetic marker, improving fertility, mega-analysis, Animal culture, SF1-1100

File Description: electronic resource

Relation: https://ijasr.um.ac.ir/article_44414_147b4cb70b4d93aacaf4d354c2b0d306.pdf; https://doaj.org/toc/2008-3106; https://doaj.org/toc/2423-4001

Access URL: https://doaj.org/article/be5761a4710d4fc69e5186b5eaee8948

Cross-continental environmental and genome-wide association study on children and adolescent anxiety and depression

Authors: Bishal Thapaliya, Bhaskar Ray, Britny Farahdel, Pranav Suresh, Ram Sapkota, Bharath Holla, Jayant Mahadevan, Jiayu Chen, Nilakshi Vaidya, Nora Irma Perrone-Bizzozero, Vivek Benegal, Gunter Schumann, Vince D. Calhoun, Jingyu Liu

Source: Frontiers in Psychiatry, Vol 15 (2024)

Subject Terms: anxiety, depression, regression, meta-analysis, mega-analysis, GWAS, Psychiatry, RC435-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1384298/full; https://doaj.org/toc/1664-0640

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Negative Valence in Obsessive-Compulsive Disorder: A Worldwide Mega-Analysis of Task-Based Functional Neuroimaging Data of the ENIGMA-OCD Consortium

Authors: Bertolin, Sara ^{1, 2, 3}, Beyer, Nicole ⁴, Castelhano, Joao ⁵, Choi, Sunah ⁶, Couto, Beatriz ⁷, Real, Eva ^{1, 3}, Segalas, Cinto ^{1, 3}, Sousa, Nuno ^{7, 8}, Uhlmann, Anne ⁴, Zhao, Yijie ^{9, 10}, Dzinalija, Nadza ^{a, b, c, d, ∗}, Vriend, Chris ^{a, b, c, d}, Waller, Lea ^e, Simpson, H. Blair ^{f, g}, Ivanov, Iliyan ^h, Agarwal, Sri Mahavir ^{i, j, k}, Alonso, Pino ^{l, m, n}, Backhausen, Lea L. ^o, Balachander, Srinivas ⁱ, Broekhuizen, Aniek ^{a, b, c, d, p}, Castelo-Branco, Miguel ^{q, r}, Costa, Ana Daniela ^{s, t}, Cui, Hailun ^u, Denys, Damiaan ^{b, c}, Duarte, Isabel Catarina ^q, Eng, Goi Khia ^{v, w}, Erk, Susanne ^e, Fitzsimmons, Sophie M.D.D. ^{a, b, c, d}, Ipser, Jonathan ^{x, y}, Jaspers-Fayer, Fern ^{z, aa}, de Joode, Niels T. ^{a, b, c, d}, Kim, Minah ^{ab, ac}, Koch, Kathrin ^ad, Kwon, Jun Soo ^{ab, ac, ae}, van Leeuwen, Wieke ^{b, c, af}, Lochner, Christine ^ag, van Marle, Hein J.F. ^{b, c, ah}, Martinez-Zalacain, Ignacio ^{l, ai}, Menchon, Jose M. ^{l, m, n}, Morgado, Pedro ^{s, t}, Narayanaswamy, Janardhanan C. ^{i, aj, ak}, Olivier, Ian S. ^{x, y}, Picó-Pérez, Maria ^{s, al}, Postma, Tjardo S. ^{a, b, c, d, ah}, Rodriguez-Manrique, Daniela ^ad, Roessner, Veit ^o, Rus-Oswald, Oana Georgiana ^am, Shivakumar, Venkataram ⁱ, Soriano-Mas, Carles ^{l, n, an}, Stern, Emily R. ^{v, w, ao}, Stewart, S. Evelyn ^{z, aa}, van der Straten, Anouk L. ^{b, c, ap}, Sun, Bomin ^{aq, ar}, Thomopoulos, Sophia I. ^as, Veltman, Dick J. ^{b, c, d}, Vetter, Nora C. ^{o, at}, Visser, Henny ^b, Voon, Valerie ^{u, au}, Walter, Henrik ^e, van der Werf, Ysbrand D. ^{a, c, d}, van Wingen, Guido ^{b, c}, Stein, Dan J. ^{y, ag}, Thompson, Paul M. ^as, Veer, Ilya M. ^{d, av, †}, van den Heuvel, Odile A. ^{a, b, c, d, †}

Source: In Biological Psychiatry December 2024

Exploring potential biomarkers and therapeutic targets in inflammatory bowel disease: insights from a mega-analysis approach

Authors: Edia Stemmer, Tamar Zahavi, Maoz Kellerman, Liat Anabel Sinberger, Guy Shrem, Mali Salmon‐Divon

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: inflammatory bowel disease, ulcerative colitis, Crohn’s disease, biomarkers, mega-analysis, machine learning, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1353402/full; https://doaj.org/toc/1664-3224

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How much is soil nitrous oxide emission reduced with biochar application? An evaluation of meta‐analyses

Authors: Navneet Kaur, Christina Kieffer, Wei Ren, Dafeng Hui

Source: GCB Bioenergy, Vol 15, Iss 1, Pp 24-37 (2023)

Subject Terms: biochar, cropland, greenhouse gas emission, mega‐analysis, meta‐analysis, response ratio, Renewable energy sources, TJ807-830, Energy industries. Energy policy. Fuel trade, HD9502-9502.5

File Description: electronic resource

Relation: https://doaj.org/toc/1757-1693; https://doaj.org/toc/1757-1707

Access URL: https://doaj.org/article/dc6603b452bf4b72b2270d3cfb7f9f62

Combining meta- and mega- analytic approaches for multi-site diffusion imaging based genetic studies: From the ENIGMA-DTI working group

Authors: Jahanshad, Neda, Kochunov, Peter, Nichols, Thomas E, Sprooten, Emma, Mandl, Rene C, Almasy, Laura, Brouwer, Rachel M, Curran, Joanne E, de Zubicaray, Greig I, Dimitrova, Rali, Fox, Peter T, Hong, L Elliot, Landman, Bennett A, Lemaitre, Herve, Lopez, Lorna, Martin, Nicholas G, McMahon, Katie L, Mitchell, Braxton D, Olvera, Rene L, Peterson, Charles P, Sussmann, Jessika E, Toga, Arthur W, Wardlaw, Joanna M, Wright, Margaret J, Wright, Susan N, Bastin, Mark E, McIntosh, Andrew M, Boomsma, Dorret I, Kahn, Rene S, den Braber, Anouk, Deary, Ian J, Pol, Hilleke E Hulshoff, Williamson, Douglas, Blangero, John, van't Ent, Dennis, Glahn, David C, Thompson, Paul M

Source: 2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI) Biomedical Imaging (ISBI), 2014 IEEE 11th International Symposium on. :1234-1238 Apr, 2014

Relation: 2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI 2014)

Impacts of Climate Change and Agricultural Practices on Nitrogen Processes, Genes, and Soil Nitrous Oxide Emissions: A Quantitative Review of Meta-Analyses

Authors: Dafeng Hui, Avedananda Ray, Lovish Kasrija, Jaekedah Christian

Source: Agriculture, Vol 14, Iss 2, p 240 (2024)

Subject Terms: denitrification, global warming, greenhouse gas emission, mega-analysis, nitrogen fertilizer, N2O, Agriculture (General), S1-972

File Description: electronic resource

Relation: https://www.mdpi.com/2077-0472/14/2/240; https://doaj.org/toc/2077-0472

Access URL: https://doaj.org/article/17779300b71846ac94868ca948cffc4e

Concerning effective and safe dosages of vitamin D3: mega-analysis of clinically effective studies as a basis for actual evidence

Authors: I. Yu. Torshin, O. A. Gromova, N. K. Tetruashvili

Source: Медицинский совет, Vol 0, Iss 13, Pp 112-120 (2021)

Subject Terms: expert data analysis, data mining, mega-analysis of randomized trials, vitamin d dosage, micellar form, Medicine

File Description: electronic resource

Relation: https://www.med-sovet.pro/jour/article/view/6405; https://doaj.org/toc/2079-701X; https://doaj.org/toc/2658-5790

Access URL: https://doaj.org/article/da96a42b51824b4aa35a3be3b075067c

Deep vein thrombosis inhibitor may play a therapeutic role in post-stroke patients

Authors: Xixi Xiang, Di Yuan, Peiyan Kong, Ting Chen, Han Yao, Shijia Lin, Xi Zhang, Hongbao Cao

Source: BMC Medical Genetics, Vol 21, Iss S1, Pp 1-6 (2020)

Subject Terms: Deep vein thrombosis, Stroke, Mega-analysis, Pathway analysis, Multiple linear regression analysis, Internal medicine, RC31-1245, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12881-020-01108-9; https://doaj.org/toc/1471-2350

Access URL: https://doaj.org/article/5c0d9f7532684d7597f907071155a53e

Understanding the molecular association between hyperkalemia and lung squamous cell carcinomas

Authors: Xianping Meng, Hongyan Lu, Xia Jiang, Bin Huang, Song Wu, Guiping Yu, Hongbao Cao

Source: BMC Medical Genetics, Vol 21, Iss S1, Pp 1-7 (2020)

Subject Terms: Hyperkalemia, Lung squamous cell carcinomas, Mega-analysis, Pathway analysis, Multiple linear regression analysis, Internal medicine, RC31-1245, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12881-020-01099-7; https://doaj.org/toc/1471-2350

Access URL: https://doaj.org/article/497f65aab75a4b4bb6efd730fe3484b7

Bulk and Single-Nucleus Transcriptomics Highlight Intra-Telencephalic and Somatostatin Neurons in Alzheimer’s Disease

Authors: Micaela E. Consens, Yuxiao Chen, Vilas Menon, Yanling Wang, Julie A. Schneider, Philip L. De Jager, David A. Bennett, Shreejoy J. Tripathy, Daniel Felsky

Source: Frontiers in Molecular Neuroscience, Vol 15 (2022)

Subject Terms: cell type proportions, Alzheimer’s disease, somatostatin, RNA sequencing, post-mortem brain, mega-analysis, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnmol.2022.903175/full; https://doaj.org/toc/1662-5099

Access URL: https://doaj.org/article/16ad3ea5dca44dd9a532c7b3fab8cf2e

Assessment of brain age in posttraumatic stress disorder: Findings from the ENIGMA PTSD and brain age working groups

Authors: Ashley N. Clausen, Kelene A. Fercho, Molly Monsour, Seth Disner, Lauren Salminen, Courtney C. Haswell, Emily Clarke Rubright, Amanda A. Watts, M. Nicole Buckley, Adi Maron‐Katz, Anika Sierk, Antje Manthey, Benjamin Suarez‐Jimenez, Bunmi O. Olatunji, Christopher L. Averill, David Hofmann, Dick J. Veltman, Elizabeth A. Olson, Gen Li, Gina L. Forster, Henrik Walter, Jacklynn Fitzgerald, Jean Théberge, Jeffrey S. Simons, Jessica A. Bomyea, Jessie L. Frijling, John H. Krystal, Justin T. Baker, K. Luan Phan, Kerry Ressler, Laura K. M. Han, Laura Nawijn, Lauren A. M. Lebois, Lianne Schmaal, Maria Densmore, Martha E. Shenton, Mirjam vanZuiden, Murray Stein, Negar Fani, Raluca M. Simons, Richard W. J. Neufeld, Ruth Lanius, Sanne vanRooij, Saskia B.J. Koch, Serena Bonomo, Tanja Jovanovic, Terri deRoon‐Cassini, Timothy D. Ely, Vincent A. Magnotta, Xiaofu He, Chadi G. Abdallah, Amit Etkin, Christian Schmahl, Christine Larson, Isabelle M. Rosso, Jennifer Urbano Blackford, Jennifer S. Stevens, Judith K. Daniels, Julia Herzog, Milissa L. Kaufman, Miranda Olff, Richard J. Davidson, Scott R. Sponheim, Sven C. Mueller, Thomas Straube, Xi Zhu, Yuval Neria, Lee A. Baugh, James H. Cole, Paul M. Thompson, Rajendra A. Morey

Source: Brain and Behavior, Vol 12, Iss 1, Pp n/a-n/a (2022)

Subject Terms: aging, machine learning, mega‐analysis, neuroimaging, posttraumatic stress disorder, trauma, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://doaj.org/toc/2162-3279

Access URL: https://doaj.org/article/af5371d486a5431c82d155d69467d00c

Evaluating a screener to quantify PTSD risk using emergency care information: a proof of concept study

Authors: Willem F. van der Mei, Anna C. Barbano, Andrew Ratanatharathorn, Richard A. Bryant, Douglas L. Delahanty, Terri A. deRoon-Cassini, Betty S. Lai, Sarah R. Lowe, Yutaka J. Matsuoka, Miranda Olff, Wei Qi, Ulrich Schnyder, Soraya Seedat, Ronald C. Kessler, Karestan C. Koenen, Arieh Y. Shalev, International Consortium to Predict PTSD

Source: BMC Emergency Medicine, Vol 20, Iss 1, Pp 1-11 (2020)

Subject Terms: Emergency care admissions, Post-traumatic stress disorder, Peritraumatic symptoms, Sequential prediction, Mega-analysis, Special situations and conditions, RC952-1245, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12873-020-00308-z; https://doaj.org/toc/1471-227X

Access URL: https://doaj.org/article/9c44ebaa28de45d195e02855625b95a6

Predictors of real-time fMRI neurofeedback performance and improvement – A machine learning mega-analysis

Authors: Amelie Haugg, Fabian M. Renz, Andrew A. Nicholson, Cindy Lor, Sebastian J. Götzendorfer, Ronald Sladky, Stavros Skouras, Amalia McDonald, Cameron Craddock, Lydia Hellrung, Matthias Kirschner, Marcus Herdener, Yury Koush, Marina Papoutsi, Jackob Keynan, Talma Hendler, Kathrin Cohen Kadosh, Catharina Zich, Simon H. Kohl, Manfred Hallschmid, Jeff MacInnes, R. Alison Adcock, Kathryn C. Dickerson, Nan-Kuei Chen, Kymberly Young, Jerzy Bodurka, Michael Marxen, Shuxia Yao, Benjamin Becker, Tibor Auer, Renate Schweizer, Gustavo Pamplona, Ruth A. Lanius, Kirsten Emmert, Sven Haller, Dimitri Van De Ville, Dong-Youl Kim, Jong-Hwan Lee, Theo Marins, Fukuda Megumi, Bettina Sorger, Tabea Kamp, Sook-Lei Liew, Ralf Veit, Maartje Spetter, Nikolaus Weiskopf, Frank Scharnowski, David Steyrl

Source: NeuroImage, Vol 237, Iss , Pp 118207- (2021)

Subject Terms: Neurofeedback, Functional MRI, Mega-analysis, Machine learning, Real-time fMRI, Learning, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1053811921004845; https://doaj.org/toc/1095-9572

Access URL: https://doaj.org/article/a02d62b9cbe24b19b6aba414fbe6d977

Explore the Underlying Mechanism Between Atopic Dermatitis and Major Depressive Disorder

Authors: Tao Yang, Xuehua Huang, Jiajun Xu, Mingjing Situ, Qingqing Xiao, Kamil Can Kural, Yan Kang

Source: Frontiers in Genetics, Vol 12 (2021)

Subject Terms: atopic dermatitis, major depressive disorder, literature-based data mining, mega-analysis, multiple linear regression analysis, gene set enrichment analysis, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2021.640951/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/7fef98cd5aea468c9ecafcea42c88fd7

Explore the Protective Role of Obesity in the Progression of Myocardial Infarction

Authors: Siyuan Zhao, Rongyuan Cao, Shuhua Zhang, Yan Kang

Source: Frontiers in Cardiovascular Medicine, Vol 8 (2021)

Subject Terms: obesity, myocardial infarction, mega-analysis, functional networks, gene set enrichment analysis, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2021.629734/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/e82f69c8c3e344c6927197f2acbb2129

Increased power by harmonizing structural MRI site differences with the ComBat batch adjustment method in ENIGMA

Authors: Joaquim Radua, Eduard Vieta, Russell Shinohara, Peter Kochunov, Yann Quidé, Melissa J. Green, Cynthia S. Weickert, Thomas Weickert, Jason Bruggemann, Tilo Kircher, Igor Nenadić, Murray J. Cairns, Marc Seal, Ulrich Schall, Frans Henskens, Janice M. Fullerton, Bryan Mowry, Christos Pantelis, Rhoshel Lenroot, Vanessa Cropley, Carmel Loughland, Rodney Scott, Daniel Wolf, Theodore D. Satterthwaite, Yunlong Tan, Kang Sim, Fabrizio Piras, Gianfranco Spalletta, Nerisa Banaj, Edith Pomarol-Clotet, Aleix Solanes, Anton Albajes-Eizagirre, Erick J. Canales-Rodríguez, Salvador Sarro, Annabella Di Giorgio, Alessandro Bertolino, Michael Stäblein, Viola Oertel, Christian Knöchel, Stefan Borgwardt, Stefan du Plessis, Je-Yeon Yun, Jun Soo Kwon, Udo Dannlowski, Tim Hahn, Dominik Grotegerd, Clara Alloza, Celso Arango, Joost Janssen, Covadonga Díaz-Caneja, Wenhao Jiang, Vince Calhoun, Stefan Ehrlich, Kun Yang, Nicola G. Cascella, Yoichiro Takayanagi, Akira Sawa, Alexander Tomyshev, Irina Lebedeva, Vasily Kaleda, Matthias Kirschner, Cyril Hoschl, David Tomecek, Antonin Skoch, Therese van Amelsvoort, Geor Bakker, Anthony James, Adrian Preda, Andrea Weideman, Dan J. Stein, Fleur Howells, Anne Uhlmann, Henk Temmingh, Carlos López-Jaramillo, Ana Díaz-Zuluaga, Lydia Fortea, Eloy Martinez-Heras, Elisabeth Solana, Sara Llufriu, Neda Jahanshad, Paul Thompson, Jessica Turner, Theo van Erp, David Glahn, Godfrey Pearlson, Elliot Hong, Axel Krug, Vaughan Carr, Paul Tooney, Gavin Cooper, Paul Rasser, Patricia Michie, Stanley Catts, Raquel Gur, Ruben Gur, Fude Yang, Fengmei Fan, Jingxu Chen, Hua Guo, Shuping Tan, Zhiren Wang, Hong Xiang, Federica Piras, Francesca Assogna, Raymond Salvador, Peter McKenna, Aurora Bonvino, Margaret King, Stefan Kaiser, Dana Nguyen, Julian Pineda-Zapata

Source: NeuroImage, Vol 218, Iss , Pp 116956- (2020)

Subject Terms: Brain, Cortical thickness, Gray matter, Mega-analysis, Neuroimaging, Schizophrenia, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1053811920304420; https://doaj.org/toc/1095-9572

Access URL: https://doaj.org/article/b3c0237bd95d44768c113fb11e137151