Intracavitary cisplatin-fibrin followed by irradiation improved tumor control compared to the single treatments in a mesothelioma rat model

Authors: Kirschner, Michaela B., Meerang, Mayura, Orlowski, Vanessa, Furrer, Katarzyna, Tschanz, Fabienne, Grgic, Ivo, Cecconi, Virginia, van den Broek, Maries, Guckenberger, Matthias, Pruschy, Martin, Lauk, Olivia, Opitz, Isabelle

Source: In JTCVS Open December 2024 22:491-503

Exploring RNA cargo in extracellular vesicles for pleural mesothelioma detection.

Authors: Kraft, Agnieszka, Kirschner, Michaela B., Orlowski, Vanessa, Ronner, Manuel, Bodmer, Caroline, Boeva, Valentina, Opitz, Isabelle, Meerang, Mayura

Source: BMC Cancer; 2/7/2025, Vol. 25 Issue 1, p1-17, 17p

Subject Terms: PRIMARY cell culture, LINCRNA, NON-coding RNA, LIFE sciences, TRANSCRIPTOMES

Intracavitary cisplatin-fibrin chemotherapy after surgery for malignant pleural mesothelioma: A phase I trial

Authors: Opitz, Isabelle, Lauk, Olivia, Meerang, Mayura, Jetter, Alexander, Aeschlimann, Beat, Seifert, Burkhardt, Günther, Detlef, Stahel, Rolf A., Weder, Walter

Source: In The Journal of Thoracic and Cardiovascular Surgery January 2020 159(1):330-340

Cytosolic pH regulates proliferation and tumour growth by promoting expression of cyclin D1

Authors: Koch, Lisa Maria, Birkeland, Eivind Salmorin, Battaglioni, Stefania, Helle, Xiao, Meerang, Mayura, Hiltbrunner, Stefanie, Ibáñez, Alfredo J., Peter, Matthias, Curioni-Fontecedro, Alessandra, Opitz, Isabelle, Dechant, Reinhard

Source: Nature metabolism. 2(11):1212-1222

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187006117.0x000001&indx=1&recIds=ETOCvdc_100187006117.0x000001

Low Merlin expression and high Survivin labeling index are indicators for poor prognosis in patients with malignant pleural mesothelioma

Authors: Meerang, Mayura, Bérard, Karima, Friess, Martina, Bitanihirwe, Byron K.Y., Soltermann, Alex, Vrugt, Bart, Felley-Bosco, Emanuela, Bueno, Raphael, Richards, William G., Seifert, Burkhardt, Stahel, Rolf, Weder, Walter, Opitz, Isabelle

Source: In Molecular Oncology October 2016 10(8):1255-1265

Importance of excision repair cross-complementation group 1 and ribonucleotide reductase M1 as prognostic biomarkers in malignant pleural mesothelioma treated with platinum-based induction chemotherapy followed by surgery

Authors: Frischknecht, Lukas, Meerang, Mayura, Soltermann, Alex, Stahel, Rolf, Moch, Holger, Seifert, Burkhardt, Weder, Walter, Opitz, Isabelle

Source: In The Journal of Thoracic and Cardiovascular Surgery June 2015 149(6):1539-1547

PI3K/mTOR Signaling in Mesothelioma Patients Treated with Induction Chemotherapy Followed by Extrapleural Pneumonectomy

Authors: Bitanihirwe, Byron K.Y., Meerang, Mayura, Friess, Martina, Soltermann, Alex, Frischknecht, Lukas, Thies, Svenja, Felley-Bosco, Emanuela, Tsao, Ming-Sound, Allo, Ghassan, de Perrot, Marc, Seifert, Burkhardt, Moch, Holger, Stahel, Rolf, Weder, Walter, Opitz, Isabelle

Source: In Journal of Thoracic Oncology February 2014 9(2):239-247

Deletions of CDKN2A and MTAP Detected by Copy-Number Variation Array Are Associated with Loss of p16 and MTAP Protein in Pleural Mesothelioma.

Authors: Vrugt, Bart, Kirschner, Michaela B., Meerang, Mayura, Oehl, Kathrin, Wagner, Ulrich, Soltermann, Alex, Moch, Holger, Opitz, Isabelle, Wild, Peter J.

Source: Cancers; Oct2023, Vol. 15 Issue 20, p4978, 11p

Subject Terms: MESOTHELIOMA, IMMUNOHISTOCHEMISTRY, GENETIC variation, MOLECULAR pathology, TRANSFERASES, RESEARCH funding

Cullin 4B Ubiquitin Ligase Is Important for Cell Survival and Regulates TGF-β1 Expression in Pleural Mesothelioma.

Authors: Kreienbühl, Jessica, Changkhong, Sakunthip, Orlowski, Vanessa, Kirschner, Michaela B., Opitz, Isabelle, Meerang, Mayura

Source: International Journal of Molecular Sciences; Sep2023, Vol. 24 Issue 17, p13410, 15p

Subject Terms: CELL survival, HIPPO signaling pathway, UBIQUITIN, MESOTHELIOMA, CELL growth, UBIQUITINATION, UBIQUITIN ligases

Degradation-linked ubiquitin signal and proteasome are integral components of DNA double strand break repair: New perspectives for anti-cancer therapy

Authors: Ramadan, Kristijan, Meerang, Mayura

Source: In FEBS Letters 16 September 2011 585(18):2868-2875

The p97–Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8

Authors: Singh, Abhay Narayan, Oehler, Judith, Torrecilla, Ignacio, Kilgas, Susan, Li, Shudong, Vaz, Bruno, Guérillon, Claire, Fielden, John, Hernandez‐Carralero, Esperanza, Cabrera, Elisa, Tullis, Iain DC, Meerang, Mayura, Barber, Paul R, Freire, Raimundo, Parsons, Jason, Vojnovic, Borivoj, Kiltie, Anne E, Mailand, Niels, Ramadan, Kristijan

Source: EMBO journal. 38(21)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099791223.0x000001&indx=1&recIds=ETOCvdc_100099791223.0x000001

Increased urinary 1, N6-ethenodeoxyadenosine and 3, N4-ethenodeoxycytidine excretion in thalassemia patients: Markers for lipid peroxidation-induced DNA damage

Authors: Meerang, Mayura, Nair, Jagadeesan, Sirankapracha, Pornpan, Thephinlap, Chonthida, Srichairatanakool, Somdet, Fucharoen, Suthat, Bartsch, Helmut

Source: In Free Radical Biology and Medicine 2008 44(10):1863-1868

The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks.

Authors: Meerang, Mayura¹, Ritz, Danilo², Paliwal, Shreya³, Garajova, Zuzana⁴, Bosshard, Matthias⁵, Mailand, Niels⁶, Janscak, Pavel³, Hübscher, Ulrich⁵, Meyer, Hemmo², Ramadan, Kristijan⁴

Source: Nature Cell Biology. Nov2011, Vol. 13 Issue 11, p1376-1382. 7p. 1 Color Photograph, 1 Black and White Photograph, 11 Graphs.

Subject Terms: *DNA, *CELL death, *DNA repair, *UBIQUITIN, *IONIZING radiation, *GENOMES

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Importance of Cullin4 Ubiquitin Ligase in Malignant Pleural Mesothelioma.

Authors: Meerang, Mayura¹ (AUTHOR) Jessica.Kreienbuehl@usz.ch, Kreienbühl, Jessica¹ (AUTHOR), Orlowski, Vanessa¹ (AUTHOR), Müller, Seraina L. C.¹ (AUTHOR), Kirschner, Michaela B.¹ (AUTHOR), Opitz, Isabelle¹ (AUTHOR) Mayura.Meerang@usz.ch

Source: Cancers. Nov2020, Vol. 12 Issue 11, p3460. 1p.

Subject Terms: *ANIMAL experimentation, *ANTINEOPLASTIC agents, *TUMOR suppressor genes, *CELL lines, *CELLULAR signal transduction, *CHEMOKINES, *ENZYME inhibitors, *GENE expression, *MESOTHELIOMA, *MICE, *IN vivo studies, *PHARMACODYNAMICS

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P3.03-044 Is Toxicity Increased by Adding Intraoperative Chemotherapy to Preoperative Induction Chemotherapy for Mesothelioma Patients?: Topic: Mesothelioma Clinical

Authors: Lauk, Olivia, Friess, Martina, Meerang, Mayura, Kirschner, Michaela, Bommeli, Cordelia, Stahel, Rolf, Weder, Walter, Opitz, Isabelle

Source: In Journal of Thoracic Oncology January 2017 12(1) Supplement:S1372-S1373

P3.03-001 Targeting Cullin Ubiquitin Ligase Leads to Growths Arrest in Malignant Pleural Mesothelioma Cells: Topic: Mesothelioma Transitional

Authors: Meerang, Mayura, Kreienbühl, Jessica, Friess, Martina, Kirschner, Michaela, Weder, Walter, Opitz, Isabelle

Source: In Journal of Thoracic Oncology January 2017 12(1) Supplement:S1343-S1343

OA22.06 Refinement of the Prognostic miR-Score for Use in Diagnostic Specimens from Chemo-Naïve Malignant Pleural Mesothelioma Patients

Authors: Kirschner, Michaela, Vrugt, Bart, Friess, Martina, Meerang, Mayura, Wild, Peter, Van Zandwijk, Nico, Reid, Glen, Weder, Walter, Opitz, Isabelle

Source: In Journal of Thoracic Oncology January 2017 12(1) Supplement:S332-S332