An Optimized Next-Generation Sequencing Protocol for Detecting De Novo MET Amplification in Non–Small Cell Lung Cancer: Prognostic and Therapeutic Implications

Authors: Cabello-Aguilar, Simon ^{a, b}, Vendrell, Julie A. ^a, Evrard, Solène ^c, Thomas, Quentin ^d, Roch, Benoît ^e, Escudié, Frédéric ^c, Solassol, Isabelle ^f, Brousset, Pierre ^c, Mazières, Julien ^g, Solassol, Jérôme ^{a, h, ∗}

Source: In Laboratory Investigation February 2025

Real-world efficacy of the dabrafenib-trametinib (D-T) combination in BRAF V600E-mutated metastatic non-small cell lung cancer (NSCLC): Results from the IFCT-2004 BLaDE cohort

Authors: Swalduz, Aurélie ^{a, ⁎}, Beau-Faller, Michèle ^b, Planchard, David ^c, Mazieres, Julien ^d, Bayle-Bleuez, Sophie ^e, Debieuvre, Didier ^f, Fallet, Vincent ^g, Geier, Margaux ^h, Cortot, Alexis ⁱ, Couraud, Sébastien ^j, Daniel, Catherine ^k, Domblides, Charlotte ^l, Pichon, Eric ^m, Fabre, Elizabeth ⁿ, Larivé, Sébastien ^o, Lerolle, Ulrike ^p, Tomasini, Pascale ^q, Wislez, Marie ^r, Missy, Pascale ^s, Morin, Franck ^s, Westeel, Virginie ^t, Auliac, Jean-Bernard ^u

Source: In Lung Cancer January 2025 199

Neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab compared with neoadjuvant chemotherapy alone in patients with early-stage non-small-cell lung cancer (KEYNOTE-671): a randomised, double-blind, placebo-controlled, phase 3 trial

Authors: Afanasyev, Sergey, Ahmed, Samreen, Alekshun, Todd, Alves, Gustavo, Anderson, Ian, Araujo, Luiz Henrique, Arkhipov, Alexander, Arora, Arvind, Bai, Jie, Begin, Paul, Belonogov, Aleksandr, Berard, Henri, Berceanu-Ion, Radu, Bernabe Caro, Reyes, Bondarenko, Igor, Bonnet, Reiner, Bosch Barrera, Joaquim, Brocca, Carlos, Bryl, Maciej, Bulotta, Alessandra, Bylicki, Olivier, Calles Blanco, Antonio, Carcereny, Enric, Carvalho, Leticia, Cebotaru, Cristina, Chaft, Jamie, Charu, Veena, Chaves, Fabio, Chen, Jun, Chen, Ke-Neng, Chen, Haiquan, Chen, Qixun, Chen, Kevin, Chiang, Chi-Lu, Chiu, Chao-Hua, Cicenas, Saulius, Ciubotaru, Elena, Ciuleanu, Tudor, Ciurescu, Ioana, Cobb, Patrick, Coetzee, Corlia, Collins, Dearbhaile, Cortinovis, Diego, Costas, Kimberly, Costin, Dan, Cronemberger, Eduardo Henrique, Cuevo, Raymund, Cuffe, Sinead, De Marchi, Pedro Rafael Martins, de Paiva Junior, Tadeu, Delmonte, Angelo, Demedts, Ingel, Deschepper, Koenraad, Dias, Josiane, Dooms, Christophe, Duchemann, Boris, Dutra, Carolina, Duvivier, Herbert, Eigendorff, Ekkehard, Ernani, Vinicius, Faehling, Martin, Faria, Luiza, Fedenko, Alexander, Fernando, Hiran, Ferrara, Roberto, Ferrari, Vittorio, Finley, Gene, Fix, Peter, Flores, Marcos, Fourie, Samuel, Franke, Fabio, Frohling, Klaus-Peter, Furqan, Muhammad, Gal, Cristian, Galamaga, Robert, Ganea, Doina, Ganti, Apar Kishor, Gao, Shugeng, Garassino, Marina, Gentzler, Ryan, Gianni, Luca, Gilli, Marina, Girard, Nicolas, Goranov, Bojidar, Gregorc, Vanesa, Greystoke, Alastair, Grisanti, Salvatore, Grohe, Christian, Guarino, Michael, Guimaraes, Jose Luiz, Guisier, Florian, Halmos, Balazs, Hammoud, Zane Taysir, Han, Ji-Youn, Hegmane, Alinta, Heng, Fook Yew, Horinouchi, Hidehito, Horio, Yoshitsugu, Hu, Jian, Huang, Hsu-Ching, Hui, Rina, Ikeda, Norihiko, Intagliata, Salvatore, Iordan, Ingrid, Jacobs, Conrad, Jain, Kirti, Jain, Sushil, Jiang, Tao, Karaseva, Nina, Kato, Terufumi, Kaywin, Paul, Kazmi, Shayma, Keresztes, Roger, Khan, Sarah, Kim, Jhingook, Kolesnik, Olena, Kolesnik, Oleksii, Kollmeier, Jens, Komiya, Takefumi, Koontz, Michael, Krasnohrud, Yuliia, Kristedja, Timothy, Kryzhanivska, Anna, Kuroda, Hiroaki, Laktionov, Konstantin, Lambrechts, Marc, Lang, Susanne, Langleben, Adrian, Lee, Se-Hoon, Lehmann, Markus, Levchenko, Evgeny, Levenko, Oleh, Li, Shanqing, Liao, Bin-Chi, Liberman, Moishe, Lima, Iane, Liu, Geoffrey, Liu-Dumlao, Theresa, Lo Russo, Giuseppe, Lou, Yan Yan, Lowczak, Anna, Luft, Alexander, Ma, Shaohua, Majem Tarruella, Margarita, Makles, Krytsyna, Martinengo, Gaston, Martinez Marti, Alex, Matias, Danielli, Mazieres, Julien, Mazilu, Laura, Mennecier, Bertrand, Migliorino, Maria Rita, Misleh, Jamal, Molina, Julian, Morbeck, Igor, Mueller, Annette, Muto, Satoshi, Nadal Alforja, Ernest, Nesterova, Alfiya, Nishio, Wataru, Niu, Jiaxin, Novello, Silvia, O'Brien, Mary, O'Day, Steven, Ogliari, Francesca, Okada, Morihito, Pang, Yong Kek, Paramonov, Viktor, Pastor, Andrea, Pawlak, Ireneusz, Piantedosi, Francovito, Pollock, Theodore, Pope, Tony, Puig, Juan, Radhi, Saba, Rao, Suman, Rathnasabapathy, Chenthilmurugan, Reck, Martin, Reinacher-Schick, Anke, Rich, Patricia, Ritgen, Mathias, Rittmeyer, Achim, Roca, Elisa, Rodriguez-Abreu, Delvys, Ruff, Paul, Rybkin, Igor, Saji, Hisashi, Sakao, Yukinori, Sangal, Ashish, Santoro, Armando, Sardenberg, Rodrigo, Savvides, Panayiotis, Scheusan, Roxana, Schiller, Joan, Schumacher, Lana, Serke, Monika, Shim, Byoung Yong, Shimizu, Junichi, Shio, Yutaka, Sibille, Anne, Siegel, Robert, Signorelli, Diego, Smagina, Maria, Sokur, Iryna, Spicer, Jonathan, Srkalovic, Gordan, Stampleman, Laura, Starodub, Alexander, Stencel, Katarzyna, Sugio, Kenji, Surmont, Veerle, Suzuki, Hiroyuki, Tabacof, Jacques, Takamochi, Kazuya, Tan, Lijie, Tanaka, Fumihiro, Tatangelo, Marcelo, Täuscher, Dagmar, Teixeira, Carlos, Thiberville, Luc, Trukhin, Dmytro, Tsai, Chen-Liang, Tsuboi, Masahiro, Ungureanu, Andrei, Ursol, Grygorii, Vanakesa, Tonu, Vansteenkiste, Johan, Varela, Mirta, Villalona-Calero, Miguel, Villaruz, Liza, Vogel, Gunther, Voitko, Nataliia, Wakelee, Heather, Wang, Qun, Wang, Wenxiang, Wang, Chin-Chou, Wang, Sarah, Wehler, Thomas, Weksler, Benny, Wermke, Martin, Wesseler, Claas, Wirtz, Hubert, Wong, Mark, Yan, Xiaolong, Yang, Yue, Yu, Kong Leong, Zasadny, Xavier, Zemaitis, Marius, Zhang, Lanjun, Zhao, Guofang, Zhao, Qing, Zhu, Yuming, Zurawski, Bogdan, Spicer, Jonathan D ^{*, *}, Garassino, Marina C ^*, Majem, Margarita, Martinengo, Gastón L, Rodríguez-Abreu, Delvys, Chaft, Jamie E, Yang, Jing, Arunachalam, Ashwini, Keller, Steven M, Samkari, Ayman

Source: In The Lancet 28 September-4 October 2024 404(10459):1240-1252

Tepotinib plus osimertinib in patients with EGFR-mutated non-small-cell lung cancer with MET amplification following progression on first-line osimertinib (INSIGHT 2): a multicentre, open-label, phase 2 trial

Authors: Wu, Yi-Long ^*, Guarneri, Valentina, Voon, Pei Jye, Lim, Boon Khaw, Yang, Jin-Ji, Wislez, Marie, Huang, Cheng, Liam, Chong Kin, Mazieres, Julien, Tho, Lye Mun, Hayashi, Hidetoshi, Nhung, Nguyen Viet, Chia, Puey Ling, de Marinis, Filippo, Raskin, Jo, Zhou, Qinghua, Finocchiaro, Giovanna, Le, Anh Tuan, Wang, Jialei, Dooms, Christophe, Kato, Terufumi, Nadal, Ernest, Hin, How Soon, Smit, Egbert F, Wermke, Martin, Tan, Daniel, Morise, Masahiro, O'Brate, Aurora, Adrian, Svenja, Pfeiffer, Boris M, Stroh, Christopher, Juraeva, Dilafruz, Strotmann, Rainer, Goteti, Kosalaram, Berghoff, Karin, Ellers-Lenz, Barbara, Karachaliou, Niki, Le, Xiuning, Kim, Tae Min ^**

Source: In The Lancet Oncology August 2024 25(8):989-1002

Prospective cardiovascular events in patients with advanced thoracic cancer treated with immune checkpoint inhibitor

Authors: Toublanc, Anne-Claire, Faure, Maxime, Verdy, Guillaume, Rabeau, Audrey, Houard, Valérie, Veillon, Rémi, Bardel, Claire, Vergnenegre, Charlotte, Dos Santos, Pierre, Mazieres, Julien, Zysman, Maeva

Source: In European Journal of Cancer August 2024 207

Custom scoring based on ecological topology of gut microbiota associated with cancer immunotherapy outcome

Authors: Derosa, Lisa, Iebba, Valerio, Silva, Carolina Alves Costa, Piccinno, Gianmarco, Wu, Guojun, Lordello, Leonardo, Routy, Bertrand, Zhao, Naisi, Thelemaque, Cassandra, Birebent, Roxanne, Marmorino, Federica, Fidelle, Marine, Messaoudene, Meriem, Thomas, Andrew Maltez, Zalcman, Gerard, Friard, Sylvie, Mazieres, Julien, Audigier-Valette, Clarisse, Sibilot, Denis Moro, Goldwasser, François, Scherpereel, Arnaud, Pegliasco, Hervé, Ghiringhelli, François, Bouchard, Nicole, Sow, Cissé, Darik, Ines, Zoppi, Silvia, Ly, Pierre, Reni, Anna, Daillère, Romain, Deutsch, Eric, Lee, Karla A., Bolte, Laura A., Björk, Johannes R., Weersma, Rinse K., Barlesi, Fabrice, Padilha, Lucas, Finzel, Ana, Isaksen, Morten L., Escudier, Bernard, Albiges, Laurence, Planchard, David, André, Fabrice, Cremolini, Chiara, Martinez, Stéphanie, Besse, Benjamin, Zhao, Liping, Segata, Nicola, Wojcik, Jérôme, Kroemer, Guido, Zitvogel, Laurence

Source: In Cell 20 June 2024 187(13):3373-3389

A pragmatic guide for management of adverse events associated with lorlatinib

Authors: Liu, Geoffrey, Mazieres, Julien, Stratmann, Jan, Ou, Sai-Hong Ignatius, Mok, Tony, Grizzard, Mary, Goto, Yasushi, Felip, Enriqueta, Solomon, Benjamin J., Bauer, Todd M.

Source: In Lung Cancer May 2024 191

STK11/LKB1 alterations worsen the poor prognosis of KRAS mutated early-stage non-squamous non-small cell lung carcinoma, results based on the phase 2 IFCT TASTE trial

Authors: Baptiste Oudart, Jean, Garinet, Simon, Leger, Caroline, Barlesi, Fabrice, Mazières, Julien, Jeannin, Gaelle, Audigier-Valette, Clarisse, Morot-Sibilot, Denis, Langlais, Alexandra, Amour, Elodie, Mathiot, Nathalie, Birsen, Gary, Blons, Hélène, Wislez, Marie

Source: In Lung Cancer April 2024 190

Deleterious association between proton pump inhibitor and protein kinase inhibitor exposure and survival for patients with lung cancer: A nationwide cohort study

Authors: Bordet, Constance, Zureik, Mahmoud, Zelmat, Yoann, Lafaurie, Margaux, Lapeyre-Mestre, Maryse, Sommet, Agnès, Mazieres, Julien, Despas, Fabien

Source: In Cancer Treatment and Research Communications 2024 39

Size and Concentration of Cell-Free DNA Measured Directly from Blood Plasma, without Prior DNA Extraction

Authors: Boutonnet, Audrey, Pradines, Anne, Mano, Marion, Kreczman-Brun, Marion, Mazières, Julien, Favre, Gilles, Ginot, Frédéric

Source: Analytical chemistry. 95(24):9263-9270

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN633066762&indx=1&recIds=ETOCRN633066762

Pembrolizumab Plus Chemotherapy in Squamous Non–Small-Cell Lung Cancer: 5-Year Update of the Phase III KEYNOTE-407 Study

Authors: Novello, Silvia, Kowalski, Dariusz M., Luft, Alexander, Gümüş, Mahmut, Vicente, David, Mazières, Julien, Rodríguez-Cid, Jeronimo, Tafreshi, Ali, Cheng, Ying, Lee, Ki Hyeong, Golf, Alexander, Sugawara, Shunichi, Robinson, Andrew G., Halmos, Balazs, Jensen, Erin, Schwarzenberger, Paul, Pietanza, M. Catherine, Paz-Ares, Luis

Source: Journal of clinical oncology. 41(11):1999-2006

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188948740.0x000001&indx=1&recIds=ETOCvdc_100188948740.0x000001

Characterization of 164 patients with NRAS mutated non-small cell lung cancer (NSCLC)

Authors: Dehem, Agathe, Mazieres, Julien, Chour, Ali, Guisier, Florian, Ferreira, Marion, Boussageon, Maxime, Girard, Nicolas, Moro-Sibilot, Denis, Cadranel, Jacques, Zalcman, Gérard, Ricordel, Charles, Wislez, Marie, Munck, Camille, Poulet, Claire, Gauvain, Clément, Descarpentries, Clotilde, Wasielewski, Eric, Cortot, Alexis B., Baldacci, Simon

Source: In Lung Cancer December 2023 186

Patient-Reported Health-Related Quality of Life in KEYNOTE-604: Pembrolizumab or Placebo Added to Etoposide and Platinum as First-Line Therapy for Extensive-Stage SCLC

Authors: Kim, Hye Ryun, Awad, Mark M., Navarro, Alejandro, Gottfried, Maya, Peters, Solange, Csőszi, Tibor, Cheema, Parneet K., Rodriguez-Abreu, Delvys, Wollner, Mirjana, Yang, James Chih-Hsin, Mazieres, Julien, Orlandi, Francisco J., Luft, Alexander, Gümüş, Mahmut, Kato, Terufumi, Kalemkerian, Gregory P., Luo, Yiwen, Santorelli, Melissa L., Pietanza, M. Catherine, Rudin, Charles M.

Source: In JTO Clinical and Research Reports November 2023 4(11)

MET Exon 14 Skipping in NSCLC: A Systematic Literature Review of Epidemiology, Clinical Characteristics, and Outcomes

Authors: Mazieres, Julien, Vioix, Helene, Pfeiffer, Boris M., Campden, Rhiannon I., Chen, Zhiyuan, Heeg, Bart, Cortot, Alexis B.

Source: In Clinical Lung Cancer September 2023 24(6):483-497

VEGFR2 and CD34 expression associated with longer survival in patients with pleural mesothelioma in the IFCT-GFPC-0701 MAPS phase 3 trial

Authors: Levallet, Guénaëlle, Dubois, Fatéméh, Elie, Nicolas, Creveuil, Christian, Brosseau, Solenn, Danel, Claire, Scherpereel, Arnaud, Lantuejoul, Sylvie, Mazières, Julien, Greillier, Laurent, Audigier-Valette, Clarisse, Bergot, Emmanuel, Moro-Sibilot, Denis, Molinier, Olivier, Léna, Hervé, Monnet, Isabelle, Morin, Franck, Gounant, Valérie, Zalcman, Gérard

Source: In Lung Cancer August 2023 182

Clinical and molecular analysis of lung cancers associated with fibrosing interstitial lung disease

Authors: Héluain, Valentin, Prévot, Grégoire, Cabarrou, Bastien, Calvayrac, Olivier, Taranchon- Clermont, Estelle, Didier, Alain, Tabourier-Gouin, Sandrine, Milia, Julie, Mazières, Julien

Source: In Respiratory Medicine and Research June 2023 83

Sotorasib versus docetaxel for previously treated non-small-cell lung cancer with KRASG12C mutation: a randomised, open-label, phase 3 trial

Authors: de Langen, Adrianus Johannes, Johnson, Melissa L, Mazieres, Julien, Dingemans, Anne-Marie C, Mountzios, Giannis, Pless, Miklos, Wolf, Jürgen, Schuler, Martin, Lena, Hervé, Skoulidis, Ferdinandos, Yoneshima, Yasuto, Kim, Sang-We, Linardou, Helena, Novello, Silvia, van der Wekken, Anthonie J, Chen, Yuanbin, Peters, Solange, Felip, Enriqueta, Solomon, Benjamin J, Ramalingam, Suresh S., Dooms, Christophe, Lindsay, Colin R, Ferreira, Carlos Gil, Blais, Normand, Obiozor, Cynthia C, Wang, Yang, Mehta, Bhakti, Varrieur, Tracy, Ngarmchamnanrith, Gataree, Stollenwerk, Björn, Waterhouse, David ^*, Paz-Ares, Luis ^{*, *}

Source: In The Lancet 4-10 March 2023 401(10378):733-746

Ultrafast Gene Fusion Assessment for Nonsquamous NSCLC

Authors: Hofman, Véronique, Heeke, Simon, Bontoux, Christophe, Chalabreysse, Lara, Barritault, Marc, Bringuier, Pierre Paul, Fenouil, Tanguy, Benzerdjeb, Nazim, Begueret, Hugues, Merlio, Jean Philippe, Caumont, Charline, Piton, Nicolas, Sabourin, Jean-Christophe, Evrard, Solène, Syrykh, Charlotte, Vigier, Anna, Brousset, Pierre, Mazieres, Julien, Long-Mira, Elodie, Benzaquen, Jonathan, Boutros, Jacques, Allegra, Maryline, Tanga, Virginie, Lespinet-Fabre, Virginie, Salah, Myriam, Bonnetaud, Christelle, Bordone, Olivier, Lassalle, Sandra, Marquette, Charles-Hugo, Ilié, Marius, Hofman, Paul

Source: In JTO Clinical and Research Reports February 2023 4(2)

Patient-reported outcomes from the randomized phase 3 CROWN study of first-line lorlatinib versus crizotinib in advanced ALK-positive non-small cell lung cancer

Authors: Mazieres, Julien, Iadeluca, Laura, Shaw, Alice T., Solomon, Benjamin J., Bauer, Todd M., de Marinis, Filippo, Felip, Enriqueta, Goto, Yasushi, Kim, Dong-Wan, Mok, Tony, Reisman, Arlene, Thurm, Holger, Polli, Anna M., Liu, Geoffrey

Source: In Lung Cancer December 2022 174:146-156

Impact of pulmonary hypertension on lung cancer management

Authors: Durin, Lucile, Noël-Savina, Elise, Héluain, Valentin, Mattei, Pierre, Mazières, Julien, Prévot, Grégoire

Source: In Respiratory Medicine and Research November 2022 82