Hydroquinone impairs trophoblast migration and invasion via AHR-twist-IFITM1 axis

Authors: Maxwell, Anthony, Swanson, Grace, Thy Nguyen, Annie, Hu, Anna, Richards, Darby, You, Yuan, Stephan, Laura, Manaloto, Marcia, Liao, Aihua, Ding, Jiahui, Mor, Gil

Source: In Placenta 26 September 2024 155:88-99

Exploring the interaction of N-(benzothiazol-2-yl)pyrrolamide DNA gyrase inhibitors with the GyrB ATP-binding site lipophilic floor: A medicinal chemistry and QTAIM study

Authors: Zidar, Nace, Emanuel Cotman, Andrej, Sinnige, Wessel, Benek, Ondrej, Barančokova, Michaela, Zega, Anamarija, Peterlin Mašič, Lucija, Tomašič, Tihomir, Ilaš, Janez, Henderson, Sara R., Mundy, Julia E.A., Maxwell, Anthony, Stevenson, Clare E.M., Lawson, David M., Jan Sterk, Geert, Tosso, Rodrigo, Gutierrez, Lucas, Enriz, Ricardo D., Kikelj, Danijel

Source: In Bioorganic & Medicinal Chemistry 15 July 2024 109

Intrinsic sexual dimorphism in the placenta determines the differential response to benzene exposure

Authors: Maxwell, Anthony ¹, Adzibolosu, Nicholas ¹, Hu, Anna ¹, You, Yuan ¹, Stemmer, Paul M. ², Ruden, Douglas M. ¹, Petriello, Michael C. ³, Sadagurski, Marianna ⁴, Debarba, Lucas K. ⁴, Koshko, Lisa ⁴, Ramadoss, Jayanth ¹, Nguyen, Annie Thy ⁵, Richards, Darby ⁵, Liao, Aihua ⁶, Mor, Gil ^{1, 7, ∗}, Ding, Jiahui ^{1, ∗∗}

Source: In iScience 21 April 2023 26(4)

Single-molecule imaging of DNA gyrase activity in living Escherichia coli

Authors: Stracy, Mathew, Wollman, Adam J. M., Kaja, Elzbieta, Gapinski, Jacek, Lee, Ji-Eun, Leek, Victoria A., McKie, Shannon J., Mitchenall, Lesley A., Maxwell, Anthony, Sherratt, David J., Leake, Mark C., Zawadzki, Pawel

Subject Terms: Quantitative Biology - Biomolecules, Physics - Biological Physics

Access URL: http://arxiv.org/abs/1811.00531

Results of shared learning of a new magnetic seed localisation device – A UK iBRA-NET breast cancer localisation study

Authors: Morgan, Jenna L., Bromley, Hannah L., Dave, Rajiv V., Masannat, Yazan, Masudi, Tahir, Mylvaganam, Senthurun, Elgammal, Suzanne, Barnes, Nicola, Down, Sue, Holcombe, Chris, Potter, Shelley, Gardiner, Matthew D., Maxwell, Anthony J., Somasundaram, Santosh K., Sami, Amtul, Kirwan, Cliona, Harvey, James

Source: European journal of surgical oncology. 48(12):2408-2413

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100177399320.0x000001&indx=1&recIds=ETOCvdc_100177399320.0x000001

A simplified and easy‐to‐use HIP HOP assay provides insights into chalcone antifungal mechanisms of action

Authors: Prescott, Thomas A. K., Anaissi‐Afonso, Laura, Fox, Keith R., Maxwell, Anthony, Panaretou, Barry, Machín, Félix

Source: FEBS letters. 596(23):3087-3102

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168293331.0x000001&indx=1&recIds=ETOCvdc_100168293331.0x000001

Unresected screen-detected ductal carcinoma in situ: Outcomes of 311 women in the Forget-Me-Not 2 study

Authors: Maxwell, Anthony J., Hilton, Bridget, Clements, Karen, Dodwell, David, Dulson-Cox, Joanne, Kearins, Olive, Kirwan, Cliona, Litherland, Janet, Mylvaganam, Senthurun, Provenzano, Elena, Pinder, Sarah E., Sawyer, Elinor, Shaaban, Abeer M., Sharma, Nisha, Stobart, Hilary, Wallis, Matthew G., Thompson, Alastair M.

Source: Breast. 61:145-155

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167300687.0x000001&indx=1&recIds=ETOCvdc_100167300687.0x000001

Mechanisms of immune regulation by the placenta: Role of type I interferon and interferon‐stimulated genes signaling during pregnancy*

Authors: Ding, Jiahui, Maxwell, Anthony, Adzibolosu, Nicholas, Hu, Anna, You, Yuan, Liao, Aihua, Mor, Gil

Source: Immunological reviews. 308(1):9-24

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155656597.0x000001&indx=1&recIds=ETOCvdc_100155656597.0x000001

De novo design of type II topoisomerase inhibitors as potential antimicrobial agents targeting a novel binding regionElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d2md00049k

Authors: Orritt, Kyle M., Feng, Lipeng, Newell, Juliette F., Sutton, Jack N., Grossman, Scott, Germe, Thomas, Abbott, Lauren R., Jackson, Holly L., Bury, Benjamin K. L., Maxwell, Anthony, McPhillie, Martin J., Fishwick, Colin W. G.

Source: RSC medicinal chemistry. 13(7):831-839

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100156145190.0x000001&indx=1&recIds=ETOCvdc_100156145190.0x000001

Breast cancer risk stratification in women of screening age: Incremental effects of adding mammographic density, polygenic risk, and a gene panel

Authors: Evans, D. Gareth R., van Veen, Elke M., Harkness, Elaine F., Brentnall, Adam R., Astley, Susan M., Byers, Helen, Woodward, Emma R., Sampson, Sarah, Southworth, Jake, Howell, Sacha J., Maxwell, Anthony J., Newman, William G., Cuzick, Jack, Howell, Anthony

Source: In Genetics in Medicine July 2022 24(7):1485-1494

The pentapeptide-repeat protein, MfpA, interacts with mycobacterial DNA gyrase as a DNA T-segment mimic

Authors: Feng, Lipeng, Mundy, Julia E. A., Stevenson, Clare E. M., Mitchenall, Lesley A., Lawson, David M., Mi, Kaixia, Maxwell, Anthony

Source: Proceedings of the National Academy of Sciences of the United States of America, 2021 Mar . 118(11), 1-12.

Access URL: https://www.jstor.org/stable/27027618

Management and 5-year outcomes in 9938 women with screen-detected ductal carcinoma in situ: the UK Sloane Project

Authors: Thompson, Alastair, Francis, Adele, Sibbering, Mark, Bishop, Hugh, Carpenter, Robert, George, W.D., Lee, Martin, Nicholson, Stewart, Dobson, Hilary, Evans, Andy, Maxwell, Anthony, Wallis, Matthew, Dodwell, David, Sawyer, Elinor, Adlard, Julian, Dewar, John, Ross, Gillian, Wilcox, Maggie, Hanby, Andrew, Pinder, Sarah, Speirs, Valerie, Thomas, Jeremy, Ellis, Ian, Lakhani, Sunil, Macartney, James, Tomlinson, Ian, Cheung, Shan, Lawrence, Gill, Ball, Graham, Clements, Karen, Hilton, Bridget, Kearins, Olive, Wheaton, Margot, Thompson, Alastair M., Pinder, Sarah E., Ball, Graham R., Thomas, Jeremy St J., Maxwell, Anthony J., Wallis, Matthew G., Dodwell, David J.

Source: In European Journal of Cancer September 2018 101:210-219

Seroprevalence of SARS-CoV-2 immunoglobulins in pregnant women and neonatal cord blood from a highly impacted region

Authors: Zambrano, Hector, Anchundia, Ketty, Aviles, Dalila, Andaluz, Ruffo, Calderon, Nathaly, Torres, Estefanie, Gonzalez-Granda, Nicolas, Maxwell, Anthony, Chen, Kang, Gonik, Bernard, Mor, Gil

Source: Placenta. 115:146-150

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176148402.0x000001&indx=1&recIds=ETOCvdc_100176148402.0x000001

Identification of key signaling pathways induced by SARS‐CoV2 that underlie thrombosis and vascular injury in COVID‐19 patients

Authors: Maxwell, Anthony J., Ding, Jiahui, You, Yuan, Dong, Zhong, Chehade, Hussein, Alvero, Ayesha, Mor, Yechiel, Draghici, Sorin, Mor, Gil

Source: Journal of leukocyte biology. 109(1):35-47

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114294068.0x000001&indx=1&recIds=ETOCvdc_100114294068.0x000001

DNA Topoisomerase Inhibitors: Trapping a DNA-Cleaving Machine in Motion

Authors: Bax, Benjamin D., Murshudov, Garib, Maxwell, Anthony, Germe, Thomas

Source: In Journal of Molecular Biology 23 August 2019 431(18):3427-3449

The Microbial Toxin Microcin B17: Prospects for the Development of New Antibacterial Agents

Authors: Collin, Frederic, Maxwell, Anthony

Source: In Journal of Molecular Biology 23 August 2019 431(18):3400-3426

New insights into the binding mode of pyridine-3-carboxamide inhibitors of E. coli DNA gyrase

Authors: Narramore, Sarah, Stevenson, Clare E.M., Maxwell, Anthony, Lawson, David M., Fishwick, Colin W.G.

Source: In Bioorganic & Medicinal Chemistry 15 August 2019 27(16):3546-3550

Impalpable breast lesion localisation, a logistical challenge: results of the UK iBRA-NET national practice questionnaire

Authors: Somasundaram, Santosh K., Potter, Shelley, Elgammal, Suzanne, Maxwell, Anthony J., Sami, Amtul S., Down, Sue K., Dave, Rajiv V., Harvey, James

Source: Breast cancer research and treatment. 185(1):13-20

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193242612.0x000001&indx=1&recIds=ETOCvdc_100193242612.0x000001

Structural and mechanistic analysis of ATPase inhibitors targeting mycobacterial DNA gyrase

Authors: Henderson, Sara R, Stevenson, Clare E M, Malone, Brandon, Zholnerovych, Yelyzaveta, Mitchenall, Lesley A, Pichowicz, Mark, McGarry, David H, Cooper, Ian R, Charrier, Cedric, Salisbury, Anne-Marie, Lawson, David M, Maxwell, Anthony

Source: Journal of antimicrobial chemotherapy. 75(10):2835-2842

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108463470.0x000001&indx=1&recIds=ETOCvdc_100108463470.0x000001

Highly sensitive mapping of in vitro type II topoisomerase DNA cleavage sites with SHAN-seq.

Authors: Morgan, Ian L, McKie, Shannon J, Kim, Rachel, Seol, Yeonee, Xu, Jing, Harami, Gabor M, Maxwell, Anthony, Neuman, Keir C

Source: Nucleic Acids Research; 9/9/2024, Vol. 52 Issue 16, p9777-9787, 11p