CD40-TRAF6 inhibition suppresses cardiovascular inflammation, oxidative stress and functional complications in a mouse model of arterial hypertension

Authors: Lea Strohm, Henning Ubbens, Dominika Mihalikova, Alexander Czarnowski, Paul Stamm, Michael Molitor, Stefanie Finger, Matthias Oelze, Dorothee Atzler, Philip Wenzel, Philipp Lurz, Thomas Münzel, Christian Weber, Esther Lutgens, Andreas Daiber, Steffen Daub

Source: Redox Biology, Vol 80, Iss , Pp 103520- (2025)

Subject Terms: Arterial hypertension, Endothelial function, Blood pressure, Inflammation, CD40(L)-TRAF6 signaling, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231725000333; https://doaj.org/toc/2213-2317

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Interventions by Cardiovascular Drugs Against Aircraft Noise-Induced Cardiovascular Oxidative Stress and Damage

Authors: Marin Kuntić, Ivana Kuntić, Jiayin Zheng, Leonardo Nardi, Matthias Oelze, Arijan Valar, Dominika Mihaliková, Lea Strohm, Henning Ubbens, Qi Tang, Liyu Zhang, Guilherme Horta, Paul Stamm, Omar Hahad, Dilja Krueger-Burg, Huige Li, Sebastian Steven, Adrian Gericke, Michael J. Schmeisser, Thomas Münzel, Andreas Daiber

Source: Antioxidants, Vol 14, Iss 1, p 59 (2025)

Subject Terms: aircraft noise exposure, high blood pressure, endothelial dysfunction, oxidative stress, inflammation, preventive therapy, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/14/1/59; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/4e91bce2a3064711a5a6991950d8df80

Vascular dysfunction and arterial hypertension in experimental celiac disease are mediated by gut-derived inflammation and oxidative stress

Authors: Karin Keppeler, Aline Pesi, Simon Lange, Johanna Helmstädter, Lea Strohm, Henning Ubbens, Marin Kuntić, Ivana Kuntić, Dominika Mihaliková, Ksenija Vujačić-Mirski, Alexandra Rosenberger, Leonie Küster, Charlotte Frank, Matthias Oelze, Stefanie Finger, Agnieszka Zakrzewska, Elena Verdu, Johannes Wild, Susanne Karbach, Philip Wenzel, Philipp Wild, David Leistner, Thomas Münzel, Andreas Daiber, Detlef Schuppan, Sebastian Steven

Source: Redox Biology, Vol 70, Iss , Pp 103071- (2024)

Subject Terms: Celiac disease, Arterial hypertension, Endothelial dysfunction, Oxidative stress, Vascular inflammation, Interleukin-17A, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231724000478; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/904e326b45ef4db18421f8a462304e01

Co-exposure to urban particulate matter and aircraft noise adversely impacts the cerebro-pulmonary-cardiovascular axis in mice

Authors: Marin Kuntic, Ivana Kuntic, Roopesh Krishnankutty, Adrian Gericke, Matthias Oelze, Tristan Junglas, Maria Teresa Bayo Jimenez, Paul Stamm, Margaret Nandudu, Omar Hahad, Karin Keppeler, Steffen Daub, Ksenija Vujacic-Mirski, Sanela Rajlic, Lea Strohm, Henning Ubbens, Qi Tang, Subao Jiang, Yue Ruan, Kenneth G. Macleod, Sebastian Steven, Thomas Berkemeier, Ulrich Pöschl, Jos Lelieveld, Hartmut Kleinert, Alex von Kriegsheim, Andreas Daiber, Thomas Münzel

Source: Redox Biology, Vol 59, Iss , Pp 102580- (2023)

Subject Terms: Environmental risk factors, Traffic noise exposure, Air pollution, Oxidative stress, Inflammation, Cardiovascular risk, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231722003524; https://doaj.org/toc/2213-2317

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Effects of Resveratrol on Vascular Function in Retinal Ischemia-Reperfusion Injury

Authors: Panagiotis Chronopoulos, Caroline Manicam, Jenia Kouchek Zadeh, Panagiotis Laspas, Johanna Charlotte Unkrig, Marie Luise Göbel, Aytan Musayeva, Norbert Pfeiffer, Matthias Oelze, Andreas Daiber, Huige Li, Ning Xia, Adrian Gericke

Source: Antioxidants, Vol 12, Iss 4, p 853 (2023)

Subject Terms: arterioles, ischemia-reperfusion injury, reactive oxygen species, resveratrol, retina, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/12/4/853; https://doaj.org/toc/2076-3921

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Long-Term Effects of Aircraft Noise Exposure on Vascular Oxidative Stress, Endothelial Function and Blood Pressure: No Evidence for Adaptation or Tolerance Development

Authors: Katie Frenis, Sanela Kalinovic, Benjamin P. Ernst, Miroslava Kvandova, Ahmad Al Zuabi, Marin Kuntic, Matthias Oelze, Paul Stamm, Maria Teresa Bayo Jimenez, Agnieszka Kij, Karin Keppeler, Veronique Klein, Lea Strohm, Henning Ubbens, Steffen Daub, Omar Hahad, Swenja Kröller-Schön, Michael J. Schmeisser, Stefan Chlopicki, Jonas Eckrich, Sebastian Strieth, Andreas Daiber, Sebastian Steven, Thomas Münzel

Source: Frontiers in Molecular Biosciences, Vol 8 (2022)

Subject Terms: acute and chronic aircraft noise exposure, hypertension, endothelial dysfunction, oxidative stress, hearing threshold by audiometry, stress adaptation, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2021.814921/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/4f079d332b40404090ea15ab5ec4c47f

Redox Switches in Noise-Induced Cardiovascular and Neuronal Dysregulation

Authors: Katie Frenis, Marin Kuntic, Omar Hahad, Maria Teresa Bayo Jimenez, Matthias Oelze, Steffen Daub, Sebastian Steven, Thomas Münzel, Andreas Daiber

Source: Frontiers in Molecular Biosciences, Vol 8 (2021)

Subject Terms: sources of reactive oxygen species, redox switches, oxidative stress, cardiovascular disease, neuronal complications, traffic noise exposure, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2021.784910/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/bf47ce30b4974e83b327377e2cb459d3

Aircraft noise exposure drives the activation of white blood cells and induces microvascular dysfunction in mice

Authors: Jonas Eckrich, Katie Frenis, Giovanny Rodriguez-Blanco, Yue Ruan, Subao Jiang, Maria Teresa Bayo Jimenez, Marin Kuntic, Matthias Oelze, Omar Hahad, Huige Li, Adrian Gericke, Sebastian Steven, Sebastian Strieth, Alex von Kriegsheim, Thomas Münzel, Benjamin Philipp Ernst, Andreas Daiber

Source: Redox Biology, Vol 46, Iss , Pp 102063- (2021)

Subject Terms: Aircraft noise exposure, Inflammatory phenotype, Plasma proteome, Dorsal skinfold model, Microvascular dysfunction, Phagocytic NADPH oxidase, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231721002226; https://doaj.org/toc/2213-2317

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Inhibition of Rac1 GTPase Decreases Vascular Oxidative Stress, Improves Endothelial Function, and Attenuates Atherosclerosis Development in Mice

Authors: Sebastian Zimmer, Philip Roger Goody, Matthias Oelze, Alexander Ghanem, Cornelius F. Mueller, Ulrich Laufs, Andreas Daiber, Felix Jansen, Georg Nickenig, Sven Wassmann

Source: Frontiers in Cardiovascular Medicine, Vol 8 (2021)

Subject Terms: atherosclerosis, endothelial function, oxidative stress, free radicals, Rac1, GTPases, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2021.680775/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/7c8c8786524e44308c696a0997cb3766

In vivo analysis of noise dependent activation of white blood cells and microvascular dysfunction in mice

Authors: Jonas Eckrich, Yue Ruan, Subao Jiang, Katie Frenis, Giovanny Rodriguez-Blanco, Alexander Philippe Maas, Maria Teresa Bayo Jimenez, Marin Kuntic, Matthias Oelze, Omar Hahad, Huige Li, Sebastian Steven, Sebastian Strieth, Alex von Kriegsheim, Thomas Münzel, Andreas Daiber, Adrian Gericke, Benjamin Philipp Ernst

Source: MethodsX, Vol 8, Iss , Pp 101540- (2021)

Subject Terms: In vivo fluorescence microscopy and cerebral arteriole cannulation to assess noise induced changes in activation of white blood cells and microvascular dysfunction, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2215016121003320; https://doaj.org/toc/2215-0161

Access URL: https://doaj.org/article/efc28514670c40c081a47b3afbadd0d8

Exacerbation of adverse cardiovascular effects of aircraft noise in an animal model of arterial hypertension

Authors: Sebastian Steven, Katie Frenis, Sanela Kalinovic, Miroslava Kvandova, Matthias Oelze, Johanna Helmstädter, Omar Hahad, Konstantina Filippou, Kamil Kus, Chiara Trevisan, Klaus-Dieter Schlüter, Kerstin Boengler, Stefan Chlopicki, Katrin Frauenknecht, Rainer Schulz, Mette Sorensen, Andreas Daiber, Swenja Kröller-Schön, Thomas Münzel

Source: Redox Biology, Vol 34, Iss , Pp 101515- (2020)

Subject Terms: Environmental noise exposure, Arterial hypertension, Vascular oxidative stress, Inflammation, Endothelial function, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231720302809; https://doaj.org/toc/2213-2317

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Oxidative stress and inflammation contribute to traffic noise-induced vascular and cerebral dysfunction via uncoupling of nitric oxide synthases

Authors: Andreas Daiber, Swenja Kröller-Schön, Matthias Oelze, Omar Hahad, Huige Li, Rainer Schulz, Sebastian Steven, Thomas Münzel

Source: Redox Biology, Vol 34, Iss , Pp 101506- (2020)

Subject Terms: Environmental risk factors, Traffic noise exposure, Oxidative stress, NOS uncoupling, Cardiovascular disease, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231720302603; https://doaj.org/toc/2213-2317

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Measurement of Tetrahydrobiopterin in Animal Tissue Samples by HPLC with Electrochemical Detection—Protocol Optimization and Pitfalls

Authors: Ksenija Vujacic-Mirski, Matthias Oelze, Ivana Kuntic, Marin Kuntic, Sanela Kalinovic, Huige Li, Jacek Zielonka, Thomas Münzel, Andreas Daiber

Source: Antioxidants, Vol 11, Iss 6, p 1182 (2022)

Subject Terms: tetrahydrobiopterin, HPLC with electrochemical detection, oxidative stress, sepsis, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/11/6/1182; https://doaj.org/toc/2076-3921

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Mechanistic Insights into Inorganic Nitrite-Mediated Vasodilation of Isolated Aortic Rings under Oxidative/Hypertensive Conditions and S-Nitros(yl)ation of Proteins in Germ-Free Mice

Authors: Paul Stamm, Sanela Kalinovic, Matthias Oelze, Sebastian Steven, Alexander Czarnowski, Miroslava Kvandova, Franziska Bayer, Christoph Reinhardt, Thomas Münzel, Andreas Daiber

Source: Biomedicines, Vol 10, Iss 3, p 730 (2022)

Subject Terms: inorganic nitrite, oxidative stress, arterial hypertension, vascular function, metabolism and bioactivation, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/10/3/730; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/5fa94e95f02142379dc54414a03384ef

Lack of Endothelial α1AMPK Reverses the Vascular Protective Effects of Exercise by Causing eNOS Uncoupling

Authors: Thomas Jansen, Miroslava Kvandová, Isabella Schmal, Sanela Kalinovic, Paul Stamm, Marin Kuntic, Marc Foretz, Benoit Viollet, Andreas Daiber, Matthias Oelze, John F. Keaney, Thomas Münzel, Eberhard Schulz, Swenja Kröller-Schön

Source: Antioxidants, Vol 10, Iss 12, p 1974 (2021)

Subject Terms: α1AMPK, endothelial cells, exercise training, reactive oxygen species, endothelial dysfunction, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/10/12/1974; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/c3092ec682ea409c88933837019f9feb

The SGLT2 inhibitor empagliflozin improves the primary diabetic complications in ZDF rats

Authors: Sebastian Steven, Matthias Oelze, Alina Hanf, Swenja Kröller-Schön, Fatemeh Kashani, Siyer Roohani, Philipp Welschof, Maximilian Kopp, Ute Gödtel-Armbrust, Ning Xia, Huige Li, Eberhard Schulz, Karl J. Lackner, Leszek Wojnowski, Serge P. Bottari, Philip Wenzel, Eric Mayoux, Thomas Münzel, Andreas Daiber

Source: Redox Biology, Vol 13, Iss C, Pp 370-385 (2017)

Subject Terms: SGLT2 inhibitor, Zucker diabetic fatty rats, Diabetes, Oxidative stress, Endothelial dysfunction, Low-grade inflammation, AGE/RAGE signaling, β-cell content, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231717303932; https://doaj.org/toc/2213-2317

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European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

Authors: Javier Egea, Isabel Fabregat, Yves M. Frapart, Pietro Ghezzi, Agnes Görlach, Thomas Kietzmann, Kateryna Kubaichuk, Ulla G. Knaus, Manuela G. Lopez, Gloria Olaso-Gonzalez, Andreas Petry, Rainer Schulz, Jose Vina, Paul Winyard, Kahina Abbas, Opeyemi S. Ademowo, Catarina B. Afonso, Ioanna Andreadou, Haike Antelmann, Fernando Antunes, Mutay Aslan, Markus M. Bachschmid, Rui M. Barbosa, Vsevolod Belousov, Carsten Berndt, David Bernlohr, Esther Bertrán, Alberto Bindoli, Serge P. Bottari, Paula M. Brito, Guia Carrara, Ana I. Casas, Afroditi Chatzi, Niki Chondrogianni, Marcus Conrad, Marcus S. Cooke, João G. Costa, Antonio Cuadrado, Pham My-Chan Dang, Barbara De Smet, Bilge Debelec–Butuner, Irundika H.K. Dias, Joe Dan Dunn, Amanda J. Edson, Mariam El Assar, Jamel El-Benna, Péter Ferdinandy, Ana S. Fernandes, Kari E. Fladmark, Ulrich Förstermann, Rashid Giniatullin, Zoltán Giricz, Anikó Görbe, Helen Griffiths, Vaclav Hampl, Alina Hanf, Jan Herget, Pablo Hernansanz-Agustín, Melanie Hillion, Jingjing Huang, Serap Ilikay, Pidder Jansen-Dürr, Vincent Jaquet, Jaap A. Joles, Balaraman Kalyanaraman, Danylo Kaminskyy, Mahsa Karbaschi, Marina Kleanthous, Lars-Oliver Klotz, Bato Korac, Kemal Sami Korkmaz, Rafal Koziel, Damir Kračun, Karl-Heinz Krause, Vladimír Křen, Thomas Krieg, João Laranjinha, Antigone Lazou, Huige Li, Antonio Martínez-Ruiz, Reiko Matsui, Gethin J. McBean, Stuart P. Meredith, Joris Messens, Verónica Miguel, Yuliya Mikhed, Irina Milisav, Lidija Milković, Antonio Miranda-Vizuete, Miloš Mojović, María Monsalve, Pierre-Alexis Mouthuy, John Mulvey, Thomas Münzel, Vladimir Muzykantov, Isabel T.N. Nguyen, Matthias Oelze, Nuno G. Oliveira, Carlos M. Palmeira, Nikoletta Papaevgeniou, Aleksandra Pavićević, Brandán Pedre, Fabienne Peyrot, Marios Phylactides, Gratiela G. Pircalabioru, Andrew R. Pitt, Henrik E. Poulsen, Ignacio Prieto, Maria Pia Rigobello, Natalia Robledinos-Antón, Leocadio Rodríguez-Mañas, Anabela P. Rolo, Francis Rousset, Tatjana Ruskovska, Nuno Saraiva, Shlomo Sasson, Katrin Schröder, Khrystyna Semen, Tamara Seredenina, Anastasia Shakirzyanova, Geoffrey L. Smith, Thierry Soldati, Bebiana C. Sousa, Corinne M. Spickett, Ana Stancic, Marie José Stasia, Holger Steinbrenner, Višnja Stepanić, Sebastian Steven, Kostas Tokatlidis, Erkan Tuncay, Belma Turan, Fulvio Ursini, Jan Vacek, Olga Vajnerova, Kateřina Valentová, Frank Van Breusegem, Lokman Varisli, Elizabeth A. Veal, A. Suha Yalçın, Olha Yelisyeyeva, Neven Žarković, Martina Zatloukalová, Jacek Zielonka, Rhian M. Touyz, Andreas Papapetropoulos, Tilman Grune, Santiago Lamas, Harald H.H.W. Schmidt, Fabio Di Lisa, Andreas Daiber

Source: Redox Biology, Vol 13, Iss C, Pp 94-162 (2017)

Subject Terms: Reactive oxygen species, Reactive nitrogen species, Redox signaling, Oxidative stress, Antioxidants, Redox therapeutics, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231717303373; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/637c0e34ca5240b4924d5b20463b39fc

Taking up the cudgels for the traditional reactive oxygen and nitrogen species detection assays and their use in the cardiovascular system

Authors: Andreas Daiber, Matthias Oelze, Sebastian Steven, Swenja Kröller-Schön, Thomas Münzel

Source: Redox Biology, Vol 12, Iss , Pp 35-49 (2017)

Subject Terms: Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231716304712; https://doaj.org/toc/2213-2317

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Betulinic Acid Protects from Ischemia-Reperfusion Injury in the Mouse Retina

Authors: Aytan Musayeva, Johanna C. Unkrig, Mayagozel B. Zhutdieva, Caroline Manicam, Yue Ruan, Panagiotis Laspas, Panagiotis Chronopoulos, Marie L. Göbel, Norbert Pfeiffer, Christoph Brochhausen, Andreas Daiber, Matthias Oelze, Huige Li, Ning Xia, Adrian Gericke

Source: Cells, Vol 10, Iss 9, p 2440 (2021)

Subject Terms: arterioles, betulinic acid, ischemia-reperfusion injury, reactive oxygen species, retina, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/9/2440; https://doaj.org/toc/2073-4409

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GLP-1 Analog Liraglutide Improves Vascular Function in Polymicrobial Sepsis by Reduction of Oxidative Stress and Inflammation

Authors: Johanna Helmstädter, Karin Keppeler, Franziska Aust, Leonie Küster, Katie Frenis, Konstantina Filippou, Ksenija Vujacic-Mirski, Simeon Tsohataridis, Sanela Kalinovic, Swenja Kröller-Schön, Matthias Oelze, Markus Bosmann, Thomas Münzel, Andreas Daiber, Sebastian Steven

Source: Antioxidants, Vol 10, Iss 8, p 1175 (2021)

Subject Terms: glucagon-like peptide-1 (GLP-1), incretins, liraglutide, peritoneal and polymicrobial sepsis, cecal ligation and puncture (CLP), endothelial dysfunction, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/10/8/1175; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/d8c2234ea8ae4b79a49409808a87e391