Air temperature and humidity impact out-of-hospital-cardiac-arrests in Germany: A 10-year cohort study from the German Resuscitation Registry

Authors: Maximilian Burger, Patrick Ristau, Andreas Bohn, Matthias Fischer, Ingvild Beathe Myrhaugen Tjelmeland, Stephan Seewald, Jan-Thorsten Gräsner, Jan Wnent

Source: Resuscitation Plus, Vol 20, Iss , Pp 100750- (2024)

Subject Terms: OHCA, Out-of-hospital-cardiac-arrest, Climate change, Public health, EMS, Resuscitation, Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666520424002017; https://doaj.org/toc/2666-5204

Access URL: https://doaj.org/article/2fbb8711ba0f4ac287bc4ff4912279fc

The German Resuscitation Registry – Epidemiological data for out-of-hospital and in-hospital cardiac arrest

Authors: Jan Wnent, Jan-Thorsten Gräsner, Matthias Fischer, Alexandra Ramshorn-Zimmer, Andreas Bohn, Berthold Bein, Stephan Seewald

Source: Resuscitation Plus, Vol 18, Iss , Pp 100638- (2024)

Subject Terms: German resuscitation registry, Out-of-hospital cardiac arrest, Epidemiology, In-Hospital Cardiac Arrest, Resuscitation, Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666520424000894; https://doaj.org/toc/2666-5204

Access URL: https://doaj.org/article/8a9339e78af041f691646c227fa09b51

Telomere maintenance mechanisms in neuroblastoma: New insights and translational implications

Authors: Lisa Werr, Carolina Rosswog, Christoph Bartenhagen, Sally L. George, Matthias Fischer

Source: EJC Paediatric Oncology, Vol 3, Iss , Pp 100156- (2024)

Subject Terms: Neuroblastoma, Telomere maintenance, Telomerase, Alternative lengthening of telomeres, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2772610X24000151; https://doaj.org/toc/2772-610X

Access URL: https://doaj.org/article/e94637699a77469fb4b11567edb2675b

LRP8‐mediated selenocysteine uptake is a targetable vulnerability in MYCN‐amplified neuroblastoma

Authors: Hamed Alborzinia, Zhiyi Chen, Umut Yildiz, Florencio Porto Freitas, Felix C E Vogel, Julianna Patricia Varga, Jasmin Batani, Christoph Bartenhagen, Werner Schmitz, Gabriele Büchel, Bernhard Michalke, Jashuo Zheng, Svenja Meierjohann, Enrico Girardi, Elisa Espinet, Andrés F Flórez, Ancely Ferreira dos Santos, Nesrine Aroua, Tasneem Cheytan, Julie Haenlin, Lisa Schlicker, Thamara N Xavier da Silva, Adriana Przybylla, Petra Zeisberger, Giulio Superti‐Furga, Martin Eilers, Marcus Conrad, Marietta Fabiano, Ulrich Schweizer, Matthias Fischer, Almut Schulze, Andreas Trumpp, José Pedro Friedmann Angeli

Source: EMBO Molecular Medicine, Vol 15, Iss 8, Pp 1-17 (2023)

Subject Terms: ferroptosis, neuroblastoma, selenocysteine, selenoprotein, synthetic lethality, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/f738f088a5b24d4d84df76ffa09916f9

SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry

Authors: Bieke Decaesteker, Amber Louwagie, Siebe Loontiens, Fanny De Vloed, Sarah-Lee Bekaert, Juliette Roels, Suzanne Vanhauwaert, Sara De Brouwer, Ellen Sanders, Alla Berezovskaya, Geertrui Denecker, Eva D’haene, Stéphane Van Haver, Wouter Van Loocke, Jo Van Dorpe, David Creytens, Nadine Van Roy, Tim Pieters, Christophe Van Neste, Matthias Fischer, Pieter Van Vlierberghe, Stephen S. Roberts, Johannes Schulte, Sara Ek, Rogier Versteeg, Jan Koster, Johan van Nes, Mark Zimmerman, Katleen De Preter, Frank Speleman

Source: Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/c5e038d1e2b747e4b27f9e8e90add70c

Impact of the route of adrenaline administration in patients suffering from out-of-hospital cardiac arrest on 30-day survival with good neurological outcome (ETIVIO study)

Authors: Tobias Monaco, Matthias Fischer, Mark Michael, Iryna Hubar, Ralf Westenfeld, Stefan Rauch, Jan-Thorsten Gräsner, Michael Bernhard

Source: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Vol 31, Iss 1, Pp 1-9 (2023)

Subject Terms: Out-of-hospital cardiac arrest, Adrenaline, Route of drug administration, Intravenous access, Intraosseous access, Endotracheal access, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/1757-7241

Access URL: https://doaj.org/article/f0b49451c0524f10872186e3f82d4d92

Somatic rearrangements causing oncogenic ectodomain deletions of FGFR1 in squamous cell lung cancer

Authors: Florian Malchers, Lucia Nogova, Martijn H.A. van Attekum, Lukas Maas, Johannes Brägelmann, Christoph Bartenhagen, Luc Girard, Graziella Bosco, Ilona Dahmen, Sebastian Michels, Clare E. Weeden, Andreas H. Scheel, Lydia Meder, Kristina Golfmann, Philipp Schuldt, Janna Siemanowski, Jan Rehker, Sabine Merkelbach-Bruse, Roopika Menon, Oliver Gautschi, Johannes M. Heuckmann, Elisabeth Brambilla, Marie-Liesse Asselin-Labat, Thorsten Persigehl, John D. Minna, Henning Walczak, Roland T. Ullrich, Matthias Fischer, Hans Christian Reinhardt, Jürgen Wolf, Reinhard Büttner, Martin Peifer, Julie George, Roman K. Thomas

Source: The Journal of Clinical Investigation, Vol 133, Iss 21 (2023)

Subject Terms: Genetics, Oncology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/ef6247e9f6b84dbca5a0844486ed3d80

Survival after traumatic cardiac arrest is possible—a comparison of German patient-registries

Authors: Stephan Seewald, Jan Wnent, Jan-Thorsten Gräsner, Ingvild Tjelmeland, Matthias Fischer, Andreas Bohn, Bertil Bouillon, Holger Maurer, Rolf Lefering

Source: BMC Emergency Medicine, Vol 22, Iss 1, Pp 1-9 (2022)

Subject Terms: Traumatic cardiac arrest, Resuscitation, German resuscitation registry, GRR, Trauma registry, TR-DGU, Special situations and conditions, RC952-1245, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/1471-227X

Access URL: https://doaj.org/article/e06ef0c0788c4e61a3e728dd5a52bca0

Reliable assessment of telomere maintenance mechanisms in neuroblastoma

Authors: Alina Meeser, Christoph Bartenhagen, Lisa Werr, Anna-Maria Hellmann, Yvonne Kahlert, Nadine Hemstedt, Peter Nürnberg, Janine Altmüller, Sandra Ackermann, Barbara Hero, Thorsten Simon, Martin Peifer, Matthias Fischer, Carolina Rosswog

Source: Cell & Bioscience, Vol 12, Iss 1, Pp 1-16 (2022)

Subject Terms: Neuroblastoma, Telomere maintenance, Alternative lengthening of telomeres, Telomerase, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/2045-3701

Access URL: https://doaj.org/article/04d7590f1e6a4f35ba877b94d65b186b

Crystal structures of FNIP/FGxxFN motif-containing leucine-rich repeat proteins

Authors: Trevor Huyton, Mamta Jaiswal, Waltraud Taxer, Matthias Fischer, Dirk Görlich

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/3c5dd522c6bb4993ac68ed7c81e306b1

Stereo Camera Setup for 360° Digital Image Correlation to Reveal Smart Structures of Hakea Fruits

Authors: Matthias Fischer, Max D. Mylo, Leon S. Lorenz, Lars Böckenholt, Heike Beismann

Source: Biomimetics, Vol 9, Iss 3, p 191 (2024)

Subject Terms: biomimetics, functional morphology, plant biomechanics, plant motion, strain analysis, structure–function relationship, Technology

File Description: electronic resource

Relation: https://www.mdpi.com/2313-7673/9/3/191; https://doaj.org/toc/2313-7673

Access URL: https://doaj.org/article/0a0dbdb7621149bc9b354af210f4b6d1

Reducing Automotive Cooling System Complexity through an Adaptive Biomimetic Air Control Valve

Authors: Thomas Thuilot, Moses-Gereon Wullweber, Matthias Fischer, Michael Bennemann, Tobias Seidl

Source: Biomimetics, Vol 9, Iss 4, p 207 (2024)

Subject Terms: pit valve, cooling system, bordered pit, pressure-controlled, compliant, Technology

File Description: electronic resource

Relation: https://www.mdpi.com/2313-7673/9/4/207; https://doaj.org/toc/2313-7673

Access URL: https://doaj.org/article/effced63d1f7438180f5fbd5b67a38fb

Noncoding Regulatory Mutations as a Driving Event for the Oncogenic Core Regulatory Circuitries of Neuroblastoma

Authors: Vincenzo Aievola, Vito Alessandro Lasorsa, Annalaura Montella, Ferdinando Bonfiglio, Marianna Avitabile, Teresa Maiorino, Matilde Tirelli, Giuseppe D’Alterio, Matthias Fischer, Frank Westermann, Achille Iolascon, Mario Capasso

Source: Proceedings, Vol 100, Iss 1, p 18 (2024)

Subject Terms: neuroblastoma, genomics, somatic mutations, next-generation sequencing, General Works

File Description: electronic resource

Relation: https://www.mdpi.com/2504-3900/100/1/18; https://doaj.org/toc/2504-3900

Access URL: https://doaj.org/article/906571d8d144407c861ae1b77fd708a1

Mutations in ALK signaling pathways conferring resistance to ALK inhibitor treatment lead to collateral vulnerabilities in neuroblastoma cells

Authors: Mareike Berlak, Elizabeth Tucker, Mathurin Dorel, Annika Winkler, Aleixandria McGearey, Elias Rodriguez-Fos, Barbara Martins da Costa, Karen Barker, Elicia Fyle, Elizabeth Calton, Selma Eising, Kim Ober, Deborah Hughes, Eleni Koutroumanidou, Paul Carter, Reda Stankunaite, Paula Proszek, Neha Jain, Carolina Rosswog, Heathcliff Dorado-Garcia, Jan Jasper Molenaar, Mike Hubank, Giuseppe Barone, John Anderson, Peter Lang, Hedwig Elisabeth Deubzer, Annette Künkele, Matthias Fischer, Angelika Eggert, Charlotte Kloft, Anton George Henssen, Michael Boettcher, Falk Hertwig, Nils Blüthgen, Louis Chesler, Johannes Hubertus Schulte

Source: Molecular Cancer, Vol 21, Iss 1, Pp 1-19 (2022)

Subject Terms: Neuroblastoma, CRISPR screening, ALK, Resistance, NF1, NRAS, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1476-4598

Access URL: https://doaj.org/article/141d19867f1b4f5b98e903127aa48cab

The MYCN inhibitor BGA002 restores the retinoic acid response leading to differentiation or apoptosis by the mTOR block in MYCN-amplified neuroblastoma

Authors: Silvia Lampis, Salvatore Raieli, Luca Montemurro, Damiano Bartolucci, Camilla Amadesi, Sonia Bortolotti, Silvia Angelucci, Anna Lisa Scardovi, Giammario Nieddu, Lucia Cerisoli, Francesca Paganelli, Sabrina Valente, Matthias Fischer, Alberto Maria Martelli, Gianandrea Pasquinelli, Andrea Pession, Patrizia Hrelia, Roberto Tonelli

Source: Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-19 (2022)

Subject Terms: Neuroblastoma, MYCN, Retinoic acid resistance, mTOR pathway, Differentiation, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/57da51d707e148518d41d12e01cff92a

The nematode worm Caenorhabditis elegans as an animal experiment replacement for assessing the virulence of different Salmonella enterica strains

Authors: Wiebke Burkhardt, Carina Salzinger, Jennie Fischer, Burkhard Malorny, Matthias Fischer, Istvan Szabo

Source: Frontiers in Microbiology, Vol 14 (2023)

Subject Terms: Caenorhabditis elegans, Salmonella, survival assay, virulence, animal experiments, replace, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2023.1188679/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/2259c1ad0e0246888882c2b5a2fccc48

Targeted parallel DNA sequencing detects circulating tumor‐associated variants of the mitochondrial and nuclear genomes in patients with neuroblastoma

Authors: Lara Riehl, Medhanie Mulaw, Katharina Kneer, Meinhard Beer, Ambros Beer, Thomas F. Barth, Vladimir Benes, Johannes Schulte, Matthias Fischer, Klaus‐Michael Debatin, Christian Beltinger

Source: Cancer Reports, Vol 6, Iss 1, Pp n/a-n/a (2023)

Subject Terms: liquid biopsy, mitochondrial and nuclear genomes, mutational signatures, neuroblastoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2573-8348

Access URL: https://doaj.org/article/efad1390606d4a2abecc09e151b4da29

Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions

Authors: Karin Schmelz, Joern Toedling, Matt Huska, Maja C. Cwikla, Louisa-Marie Kruetzfeldt, Jutta Proba, Peter F. Ambros, Inge M. Ambros, Sengül Boral, Marco Lodrini, Celine Y. Chen, Martin Burkert, Dennis Guergen, Annabell Szymansky, Kathy Astrahantseff, Annette Kuenkele, Kerstin Haase, Matthias Fischer, Hedwig E. Deubzer, Falk Hertwig, Patrick Hundsdoerfer, Anton G. Henssen, Roland F. Schwarz, Johannes H. Schulte, Angelika Eggert

Source: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/2390ab09b04a41c28245bac3ed08f2c9

Scattering of two and three physical pions at maximal isospin from lattice QCD

Authors: Matthias Fischer, Bartosz Kostrzewa, Liuming Liu, Fernando Romero-López, Martin Ueding, Carsten Urbach

Source: European Physical Journal C: Particles and Fields, Vol 81, Iss 5, Pp 1-19 (2021)

Subject Terms: Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798

File Description: electronic resource

Relation: https://doaj.org/toc/1434-6044; https://doaj.org/toc/1434-6052

Access URL: https://doaj.org/article/c3c09fdda7d6420c910cb006ed8b5629

Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome

Authors: Sabine A. Hartlieb, Lina Sieverling, Michal Nadler-Holly, Matthias Ziehm, Umut H. Toprak, Carl Herrmann, Naveed Ishaque, Konstantin Okonechnikov, Moritz Gartlgruber, Young-Gyu Park, Elisa Maria Wecht, Larissa Savelyeva, Kai-Oliver Henrich, Carolina Rosswog, Matthias Fischer, Barbara Hero, David T. W. Jones, Elke Pfaff, Olaf Witt, Stefan M. Pfister, Richard Volckmann, Jan Koster, Katharina Kiesel, Karsten Rippe, Sabine Taschner-Mandl, Peter Ambros, Benedikt Brors, Matthias Selbach, Lars Feuerbach, Frank Westermann

Source: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/451b2c4a26e94327b98d615c78ab75da