The tetraspanin Tspan15 is an essential subunit of an ADAM10 scissor complex

Authors: Koo, Chek Ziu, Harrison, Neale, Noy, Peter J., Szyroka, Justyna, Matthews, Alexandra L., Hsia, Hung-En, Müller, Stephan A., Tüshaus, Johanna, Goulding, Joelle, Willis, Katie, Apicella, Clara, Cragoe, Bethany, Davis, Edward, Keles, Murat, Malinova, Antonia, McFarlane, Thomas A., Morrison, Philip R., Nguyen, Hanh T.H., Sykes, Michael C., Ahmed, Haroon, Di Maio, Alessandro, Seipold, Lisa ^**, Saftig, Paul ^**, Cull, Eleanor, Pliotas, Christos, Rubinstein, Eric, Poulter, Natalie S., Briddon, Stephen J., Holliday, Nicholas D., Lichtenthaler, Stefan F., Tomlinson, Michael G.

Source: In Journal of Biological Chemistry 4 September 2020 295(36):12822-12839

TspanC8 Tetraspanins and A Disintegrin and Metalloprotease 10 (ADAM10) Interact via Their Extracellular Regions: EVIDENCE FOR DISTINCT BINDING MECHANISMS FOR DIFFERENT TspanC8 PROTEINS

Authors: Noy, Peter J., Yang, Jing, Reyat, Jasmeet S., Matthews, Alexandra L., Charlton, Alice E., Furmston, Joanna, Rogers, David A., Rainger, G. Ed, Tomlinson, Michael G.

Source: In Journal of Biological Chemistry 12 February 2016 291(7):3145-3157

Tetraspanin Tspan9 regulates platelet collagen receptor GPVI lateral diffusion and activation.

Authors: Haining, Elizabeth J.¹ (AUTHOR), Matthews, Alexandra L.¹ (AUTHOR), Noy, Peter J.¹ (AUTHOR), Romanska, Hanna M.² (AUTHOR), Harris, Helen J.¹ (AUTHOR), Pike, Jeremy^1,3 (AUTHOR), Morowski, Martina⁴ (AUTHOR), Gavin, Rebecca L.¹ (AUTHOR), Yang, Jing¹ (AUTHOR), Milhiet, Pierre-Emmanuel⁵ (AUTHOR), Berditchevski, Fedor⁶ (AUTHOR), Nieswandt, Bernhard⁴ (AUTHOR), Poulter, Natalie S.⁷ (AUTHOR), Watson, Steve P.⁷ (AUTHOR), Tomlinson, Michael G.¹ (AUTHOR) m.g.tomlinson@bham.ac.uk

Source: Platelets. Nov2017, Vol. 28 Issue 7, p629-642. 14p.

Subject Terms: *TETRASPANIN, *BLOOD platelets, *LABORATORY mice, *NEOVASCULARIZATION, *ANIMAL models in research

Regulation of A disintegrin and metalloproteinase (ADAM) family sheddases ADAM10 and ADAM17: The emerging role of tetraspanins and rhomboids.

Authors: Matthews, Alexandra L.¹ (AUTHOR) m.g.tomlinson@bham.ac.uk, Noy, Peter J.¹ (AUTHOR), Reyat, Jasmeet S.¹ (AUTHOR), Tomlinson, Michael G.¹ (AUTHOR)

Source: Platelets. Jun2017, Vol. 28 Issue 4, p333-341. 9p.

Subject Terms: *DISINTEGRINS, *METALLOPROTEINASE regulation, *METALLOPROTEINASE genetics, *TUMOR necrosis factors, *CELL membranes

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The Platelet Collagen Receptor GPVI Is Cleaved by Tspan15/ADAM10 and Tspan33/ADAM10 Molecular Scissors.

Authors: Koo, Chek Ziu^1,2 (AUTHOR) cxk543@bham.ac.uk, Matthews, Alexandra L.^1,2 (AUTHOR) allymatthews33@googlemail.com, Harrison, Neale¹ (AUTHOR) neale.harrison@celentyx.com, Szyroka, Justyna¹ (AUTHOR) justynaszyroka@gmail.com, Nieswandt, Bernhard³ (AUTHOR) bernhard.nieswandt@virchow.uni-wuerzburg.de, Gardiner, Elizabeth E.⁴ (AUTHOR) elizabeth.gardiner@anu.edu.au, Poulter, Natalie S.^2,5 (AUTHOR), Tomlinson, Michael G.^1,2 (AUTHOR) m.g.tomlinson@bham.ac.uk

Source: International Journal of Molecular Sciences. Mar2022, Vol. 23 Issue 5, p2440. 1p.

Subject Terms: *MEMBRANE proteins, *BLOOD platelets, *COLLAGEN, *TETRASPANIN, *CELL lines, *METALLOPROTEINASES, *GENOME editing

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