Neuroinflammatory gene expression profiles of reactive glia in the substantia nigra suggest a multidimensional immune response to alpha synuclein inclusions

Authors: Anna C. Stoll, Christopher J. Kemp, Joseph R. Patterson, Jacob W. Howe, Kathy Steece-Collier, Kelvin C. Luk, Caryl E. Sortwell, Matthew J. Benskey

Source: Neurobiology of Disease, Vol 191, Iss , Pp 106411- (2024)

Subject Terms: Glia, Microglia, Astrocyte, Alpha-synuclein, Neuroinflammation, Parkinson's disease, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S096999612400010X; https://doaj.org/toc/1095-953X

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Behavioral and neuropathological characterization over the adult lifespan of the human tau knock-in mouse

Authors: Matthew J. Benskey, Spencer Panoushek, Takashi Saito, Takaomi C. Saido, Tessa Grabinski, Nicholas M. Kanaan

Source: Frontiers in Aging Neuroscience, Vol 15 (2023)

Subject Terms: tau, MAPT, aging, knock-in mice, glial cells, mouse model, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnagi.2023.1265151/full; https://doaj.org/toc/1663-4365

Access URL: https://doaj.org/article/42c6d308fd0743f6b834ad35a55e0fd0

Restoring pars intermedia dopamine concentrations and tyrosine hydroxylase expression levels with pergolide: evidence from horses with pituitary pars intermedia dysfunction

Authors: Jessica S. Fortin, Matthew J. Benskey, Keith J. Lookingland, Jon S. Patterson, Erin B. Howey, John L. Goudreau, Harold C. Schott

Source: BMC Veterinary Research, Vol 16, Iss 1, Pp 1-8 (2020)

Subject Terms: Dopamine agonist, Equine, Parkinson disease animal model, Pituitary pars intermedia adenoma, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12917-020-02565-3; https://doaj.org/toc/1746-6148

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Regulation of dopamine neurotransmission from serotonergic neurons by ectopic expression of the dopamine D2 autoreceptor blocks levodopa-induced dyskinesia

Authors: Rhyomi C. Sellnow, Jordan H. Newman, Nicole Chambers, Anthony R. West, Kathy Steece-Collier, Ivette M. Sandoval, Matthew J. Benskey, Christopher Bishop, Fredric P. Manfredsson

Source: Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-17 (2019)

Subject Terms: 5-HT, Serotonin, DA, Dopamine, Dyskinesia, L-DOPA, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-018-0653-7; https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/e3d5337e194b46f3a19e621ec823fa0b

Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology

Authors: Fredric P. Manfredsson, Kelvin C. Luk, Matthew J. Benskey, Aysegul Gezer, Joanna Garcia, Nathan C. Kuhn, Ivette M. Sandoval, Joseph R. Patterson, Alana O'Mara, Reid Yonkers, Jeffrey H. Kordower

Source: Neurobiology of Disease, Vol 112, Iss , Pp 106-118 (2018)

Subject Terms: Alpha-synuclein, Enteric nervous system, Parkinson's disease, Enteric dysfunction, Prion spread, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996118300081; https://doaj.org/toc/1095-953X

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Silencing Alpha Synuclein in Mature Nigral Neurons Results in Rapid Neuroinflammation and Subsequent Toxicity

Authors: Matthew J. Benskey, Rhyomi C. Sellnow, Ivette M. Sandoval, Caryl E. Sortwell, Jack W. Lipton, Fredric P. Manfredsson

Source: Frontiers in Molecular Neuroscience, Vol 11 (2018)

Subject Terms: alpha-synuclein, knockdown, major histocompatibility complex class 1 (MHC-1), microglia, neuroinflammation, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fnmol.2018.00036/full; https://doaj.org/toc/1662-5099

Access URL: https://doaj.org/article/fc67df6934984e3a88edbedfbdefd933

Impact of age and vector construct on striatal and nigral transgene expression

Authors: Nicole K Polinski, Fredric P Manfredsson, Matthew J Benskey, D Luke Fischer, Christopher J Kemp, Kathy Steece-Collier, Ivette M Sandoval, Katrina L Paumier, Caryl E Sortwell

Source: Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)

Subject Terms: Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050117300402; https://doaj.org/toc/2329-0501

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