Ixekizumab for patients with non-radiographic axial spondyloarthritis (COAST-X): a randomised, placebo-controlled trial

Authors: Morin, Frederic, Rahman, Proton, Ariel, Federico, Berman, Alberto, Carrio, Judith, Lucero, Eleonora, Cocco, Jose Maldonado, Hidalgo, Rodolfo Pardo, Velasco, Jorge, Viola, Diego O., Grisar, Johannes, Resch, Heinrich, Scheinecker, Clemens, Melazzi, Ana Claudia, Roimicher, Luis, Scotton, Antonio Scafuto, Rodriguez, Aaron Alejandro Barrera, Molina, Francisco Fidencio Cons, Barragan, Sergio Duran, Skinner, Cassandra M., Tena, Cesar Francisco Pacheco, Remus, Cesar Ricardo Ramos, Rodriguez, Juan Cruz Rizo, Hong, Seung-Jae, Kang, Seong Wook, Lee, Chang Keun, Lee, Eun Bong, Lee, Sang Heon, Park, Min-Chan, Lee, Sang-Hoon, Dokoupilova, Eva, Dvorak, Zdenek, Malcova, Martina, Pvelka, Karel, Eklund, Kari K., Jarvinen, Pentti, Karjalainen, Anna, Paimela, Leena, Taniguchi, Yoshinori, Tsuda, Tokutaro, Tada, Kurisu, Dobashi, Hiroaki, Inui, Kentaro, Ueki, Yukitaka, Matsumoto, Yoshifuji, Hatta, Kazuhiro, Atsumi, Tatsuya, Goto, Hitoshi, Honjo, Shigeru, Matsui, Kiyoshi, Takakubo, Yuya, Neeck, Gunther, Wagner, Sylke, Braun, Jürgen, Blicharshi, Tomasz, Dudek, Anna, Hrycai, Pawel, Plebanski, Rafal, Drabiszcak-Piatkowska, Janina, Brzezicki, Jan, Krogulec, Marek, Opris-Belinski, Daniela, Ramazan, Ana Maria, Tronaru, Luminita, van de Sande, Marleen G., Matsievskaya, Galina, Schmidt, Evgeniya, Stanislav, Marina, Yakushin, Sergey, Ershova, Olga, Rebroy, Andrey, Churchill, Melvin A., Flint, Kathleen P., Greenwald, Maria, Howell, Mary P., Kaine, Jeffrey L., Kivitz, Alan, Klein, Steven J., Mueller, Eric C., Peters, Eric A., Querubin, Roel, Sayers, Michael E., Scoville, Craig D., Shanahan, Joseph C., Roseff, Richard, Hull, John E., Mallepalli, Jyothi R., Sebai, Mohamed B., Kimmel, Steven C., Goddard, David H., Mease, Philip J., Harris, Mark D., Mabaquiao, Arthur R., Diegel, Roger J., Thai, Christine, Rivera, Tania L., Perez-De Jesus, Amarilis, Soto-Raices, Oscar, Toro-Torres, Ramon, Pantojas, Carlos, Deodhar, Atul, van der Heijde, Désirée ^*, Gensler, Lianne S, Kim, Tae-Hwan, Maksymowych, Walter P, Østergaard, Mikkel, Poddubnyy, Denis, Marzo-Ortega, Helena, Bessette, Louis, Tomita, Tetsuya, Leung, Ann, Hojnik, Maja, Gallo, Gaia, Li, Xiaoqi, Adams, David, Carlier, Hilde, Sieper, Joachim

Source: In The Lancet 4-10 January 2020 395(10217):53-64

Fenebrutinib Versus Placebo or Adalimumab in Rheumatoid Arthritis: A Randomized, Double‐Blind, Phase II Trial

Authors: Cohen, Stanley, Tuckwell, Katie, Katsumoto, Tamiko R., Zhao, Rui, Galanter, Joshua, Lee, Chin, Rae, Julie, Toth, Balazs, Ramamoorthi, Nandhini, Hackney, Jason A., Berman, Alberto, Damjanov, Nemanja, Fedkov, Dmytro, Jeka, Slawomir, Chinn, Leslie W., Townsend, Michael J., Morimoto, Alyssa M., Genovese, Mark C., Porto, Alejandro, Granel, Amelia, Asnal, Cecilia, Mysler, Eduardo Fabian, Testa, Gladys Alicia, Zamora, Jose Luis Velasco, Moreno, Jose Luis Cristian, Gulin, Juan Pablo, Hofman, Julio, Ulla, Maria Rosa, Sabelli, Mirtha, Mannucci, Pablo Alejandro, Maid, Pablo Jorge, Melazzi, Ana Cláudia Cauceglia, Scotton, Antônio Scafuto, Ximenes, Antônio Carlos, Funes, Elisete, Gimenez, Emerson Alves, Marcolino, Flora Maria D'Andrea, Neto, João Francisco Marques, Keiserman, Mauro Waldemar, Radominski, Sebastião Cézar, Lima, Sônia Maria Alvarenga Anti Loduca, Pavan, Thaís Rohde, Azevedo, Valderílio Feijó, Koleva, Aneliya, Toncheva, Antoaneta, Bichovska, Daniela, Ivanova, Delina, Penev, Dimitar, Dimitrov, Emil, Mihaylova, Mariyana, Kapandjieva, Nadezhda, Marinova, Natalia, Aleksieva, Tanya, Tsvetanova, Tanya, Petranova, Tsvetanka, Popova, Valentina, Spasov, Yuliy, Toro, Carlos Enrique, Arteaga Unigarro, Carlos Ernesto, Jauregui, Edwin, Hernandez, Javier Dario Marquez, Raad, Juan Jose Jaller, Sanchez, Patricia Julieta Velez, Lee, Chang Keun, Suh, Chang‐Hee, Lee, Eun Young, Lee, Sang‐Heon, Kang, Seong Wook, Lee, Shin‐Seok, Lee, Yun Jong, Montiel, Beatriz Elena Zazueta, Pinzon de la O, Blanca Irma, Friedmann, Daniel Xibille, Lopez, Francisco Rosas, Torres, Isaura Rodriguez, Quezada, Luis Jara, Ceceña, Marco Maradiaga, Hernandez, Miguel Cortes, Salinas, Miguel Saavedra, Rapa, Agnieszka, Pawtel, Agnieszka, Zielinska, Agnieszka, Dudek, Anna, Rychlewska‐Hanczewska, Anna, Strzelecka, Anna, Racewicz, Artur, Stasiuk, Barbara, Gruszecka, Katarzyna, Dworak, Krystyna, Lowenhoff, Tomasz, Maslyanskiy, Alexey, Rebrov, Andrey, Krechikova, Diana, Zhugrova, Elena, Shmidt, Evgeniya, Matsievskaya, Galina, Vinogradova, Irina, Ler, Irina, Eliseeva, Larisa, Savina, Ludmila, Stanislav, Marina, Sandin, Mikhail, Zyablova, Natalia, Korshunov, Nikolay, Mosesova, Nino, Polovnikova, Oksana, Nesmeyanova, Olga, Samigullina, Ruzana, Moiseev, Sergey, Noskov, Sergey, Raskina, Tatiana, Popova, Tatiana, Marchenko, Valeriy, Jovanovski, Aleksandar, Stamenkovic, Bojana, Ristic, Gorica, Lazarevic, Milijanka, Veselinovic, Mirjana, Vujasinovic‐Stupar, Nada, Ostojic, Predrag, Yagensky, Andriy, Gnylorybov, Andriy, Rekalov, Dmytro, Reshotko, Dmytroo, Dzyak, Georgiy, Gasanov, Iurii, Khimion, Ludmila, Stanislavchuk, Mykola, Prykhodko, Natalya, Nadashkevych, Oleg, Bortkevych, Oleg, Abrahamovych, Orest, Yatsyshyn, Roman, Turyanytsya, Samvel, Smiyan, Svitlana, Vizir, Vadym, Kachur, Victoria, Tseluyko, Vira, Povoroznyuk, Vladyslav, Koshlia, Volodymyr, Zhdan, Vyacheslav, Lymar, Yurii, Mostovoy, Yuriy, Hawkes, Angela, Mabaquiao, Arthur, Chu, Cong‐Qiu, Scoville, Craig, Wyatt, David, Weinstein, Debra, McIlwain, Harris, Vo, Jacqueline, Poiley, Jeffrey, Forstot, Joseph, Dao, Kathryn, Turner, Mark, Genovese, Mark, Borofsky, Michael, Caldron, Paul, Waller, Philip, Levin, Robert, Metyas, Samy, Stein, Scott, Shroff, Sharukh, Pang, Shirley, Syed, Tauseef, Chindalore, Vishala

Source: Arthritis & rheumatology. 72(9):1435-1446

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108057070.0x000001&indx=1&recIds=ETOCvdc_100108057070.0x000001

Ixekizumab, an interleukin-17A antagonist in the treatment of ankylosing spondylitis or radiographic axial spondyloarthritis in patients previously untreated with biological disease-modifying anti-rheumatic drugs (COAST-V): 16 week results of a phase 3 randomised, double-blind, active-controlled and placebo-controlled trial

Authors: Churchill, Melvin, Flint, Kathleen, Gladstein, Geoffrey, Greenwald, Maria, Howell, Mary, Ince, Akgun, Kaine, Jeffrey, Mehta, Daksha, Peters, Eric, Querubin, Roel, Reveille, John, Roseff, Richard, Diegel, Roger, Thai, Christine, Bessette, Louis, Morin, Frederic, Rahman, Proton, Barrera Rodriguez, Aaron Alejandro, Cons-Molina, Fidencio, Duran Barragan, Sergio, Skinner, Cassandra, Pacheco Tena, Cesar, Ramos Remus, Cesar, Rizo Rodriguez, Juan Cruz, Hong, Seung-Jae, Lee, Yeon-Ah, Ju, Ji Hyeon, Kang, Seong Wook, Kim, Tae-Hwan, Lee, Chang Keun, Lee, Eun Bong, Lee, Sang Heon, Park, Min-Chan, Shin, Kichul, Lee, Sang-Hoon, Chen, Hung-An, Chen, Ying-Chou, Hsieh, Song-Chou, Lan, Joung-Liang, Dvorak, Zdenek, Moravcova, Radka, Malcova, Martina, Taniguchi, Yoshinori, Kishimoto, Mitsumasa, Tada, Kurisu, Dobashi, Hiroaki, Inui, Kentaro, Ueki, Yukitaka, Matsumoto, Yoshifuji, Koyama, Yoshinobu, Hatta, Kazuhiro, Atsumi, Tatsuya, Goto, Hitoshi, Matsui, Kiyoshi, Takakubo, Yuya, Neeck, Gunther, Poddubnyy, Denis, Rubbert-Roth, Andrea, Szymanska, Malgorzata, Blicharski, Tomasz, Dudek, Anna, Racewicz, Artur, Wojciechowski, Rafal, van de Sande, Marleen, Griep, Ed, Nurmohamed, Mike, Matsievskaya, Galina, Shmidt, Evgeniya, Stanislav, Marina, Yakushin, Sergey, Ershova, Olga, Rebrov, Andrey, Balazs, Tibor, Cseuz, Regina, Drescher, Edit, Poor, Gyula, van der Heijde, Désirée ^*, Cheng-Chung Wei, James, Dougados, Maxime, Mease, Philip, Deodhar, Atul, Maksymowych, Walter P, Van den Bosch, Filip, Sieper, Joachim, Tomita, Tetsuya, Landewé, Robert, Zhao, Fangyi, Krishnan, Eswar, Adams, David H., Pangallo, Beth, Carlier, Hilde

Source: In The Lancet 8-14 December 2018 392(10163):2441-2451

Ixekizumab for patients with non-radiographic axial spondyloarthritis (COAST-X): a randomised, placebo-controlled trial

Authors: Deodhar, Atul, van der Heijde, Désirée, Gensler, Lianne S, Kim, Tae-Hwan, Maksymowych, Walter P, Østergaard, Mikkel, Poddubnyy, Denis, Marzo-Ortega, Helena, Bessette, Louis, Tomita, Tetsuya, Leung, Ann, Hojnik, Maja, Gallo, Gaia, Li, Xiaoqi, Adams, David, Carlier, Hilde, Sieper, Joachim, Morin, Frederic, Rahman, Proton, Ariel, Federico, Berman, Alberto, Carrio, Judith, Lucero, Eleonora, Cocco, Jose Maldonado, Hidalgo, Rodolfo Pardo, Velasco, Jorge, Viola, Diego O., Grisar, Johannes, Resch, Heinrich, Scheinecker, Clemens, Melazzi, Ana Claudia, Roimicher, Luis, Scotton, Antonio Scafuto, Rodriguez, Aaron Alejandro Barrera, Molina, Francisco Fidencio Cons, Barragan, Sergio Duran, Skinner, Cassandra M., Tena, Cesar Francisco Pacheco, Remus, Cesar Ricardo Ramos, Rodriguez, Juan Cruz Rizo, Hong, Seung-Jae, Kang, Seong Wook, Lee, Chang Keun, Lee, Eun Bong, Lee, Sang Heon, Park, Min-Chan, Lee, Sang-Hoon, Dokoupilova, Eva, Dvorak, Zdenek, Malcova, Martina, Pvelka, Karel, Eklund, Kari K., Jarvinen, Pentti, Karjalainen, Anna, Paimela, Leena, Taniguchi, Yoshinori, Tsuda, Tokutaro, Tada, Kurisu, Dobashi, Hiroaki, Inui, Kentaro, Ueki, Yukitaka, Matsumoto, Yoshifuji, Hatta, Kazuhiro, Atsumi, Tatsuya, Goto, Hitoshi, Honjo, Shigeru, Matsui, Kiyoshi, Takakubo, Yuya, Neeck, Gunther, Wagner, Sylke, Braun, Jürgen, Blicharshi, Tomasz, Dudek, Anna, Hrycai, Pawel, Plebanski, Rafal, Drabiszcak-Piatkowska, Janina, Brzezicki, Jan, Krogulec, Marek, Opris-Belinski, Daniela, Ramazan, Ana Maria, Tronaru, Luminita, van de Sande, Marleen G., Matsievskaya, Galina, Schmidt, Evgeniya, Stanislav, Marina, Yakushin, Sergey, Ershova, Olga, Rebroy, Andrey, Churchill, Melvin A., Flint, Kathleen P., Greenwald, Maria, Howell, Mary P., Kaine, Jeffrey L., Kivitz, Alan, Klein, Steven J., Mueller, Eric C., Peters, Eric A., Querubin, Roel, Sayers, Michael E., Scoville, Craig D., Shanahan, Joseph C., Roseff, Richard, Hull, John E., Mallepalli, Jyothi R., Sebai, Mohamed B., Kimmel, Steven C., Goddard, David H., Mease, Philip J., Harris, Mark D., Mabaquiao, Arthur R., Diegel, Roger J., Thai, Christine, Rivera, Tania L., Perez-De Jesus, Amarilis, Soto-Raices, Oscar, Toro-Torres, Ramon, Pantojas, Carlos

Source: The Lancet; January 2020, Vol. 395 Issue: 10217 p53-64, 12p

Ixekizumab, an interleukin-17A antagonist in the treatment of ankylosing spondylitis or radiographic axial spondyloarthritis in patients previously untreated with biological disease-modifying anti-rheumatic drugs (COAST-V): 16 week results of a phase 3 randomised, double-blind, active-controlled and placebo-controlled trial

Authors: van der Heijde, Désirée, Cheng-Chung Wei, James, Dougados, Maxime, Mease, Philip, Deodhar, Atul, Maksymowych, Walter P, Van den Bosch, Filip, Sieper, Joachim, Tomita, Tetsuya, Landewé, Robert, Zhao, Fangyi, Krishnan, Eswar, Adams, David H., Pangallo, Beth, Carlier, Hilde, Churchill, Melvin, Flint, Kathleen, Gladstein, Geoffrey, Greenwald, Maria, Howell, Mary, Ince, Akgun, Kaine, Jeffrey, Mehta, Daksha, Peters, Eric, Querubin, Roel, Reveille, John, Roseff, Richard, Diegel, Roger, Thai, Christine, Bessette, Louis, Morin, Frederic, Rahman, Proton, Barrera Rodriguez, Aaron Alejandro, Cons-Molina, Fidencio, Duran Barragan, Sergio, Skinner, Cassandra, Pacheco Tena, Cesar, Ramos Remus, Cesar, Rizo Rodriguez, Juan Cruz, Hong, Seung-Jae, Lee, Yeon-Ah, Ju, Ji Hyeon, Kang, Seong Wook, Kim, Tae-Hwan, Lee, Chang Keun, Lee, Eun Bong, Lee, Sang Heon, Park, Min-Chan, Shin, Kichul, Lee, Sang-Hoon, Chen, Hung-An, Chen, Ying-Chou, Hsieh, Song-Chou, Lan, Joung-Liang, Dvorak, Zdenek, Moravcova, Radka, Malcova, Martina, Taniguchi, Yoshinori, Kishimoto, Mitsumasa, Tada, Kurisu, Dobashi, Hiroaki, Inui, Kentaro, Ueki, Yukitaka, Matsumoto, Yoshifuji, Koyama, Yoshinobu, Hatta, Kazuhiro, Atsumi, Tatsuya, Goto, Hitoshi, Matsui, Kiyoshi, Takakubo, Yuya, Neeck, Gunther, Poddubnyy, Denis, Rubbert-Roth, Andrea, Szymanska, Malgorzata, Blicharski, Tomasz, Dudek, Anna, Racewicz, Artur, Wojciechowski, Rafal, van de Sande, Marleen, Griep, Ed, Nurmohamed, Mike, Matsievskaya, Galina, Shmidt, Evgeniya, Stanislav, Marina, Yakushin, Sergey, Ershova, Olga, Rebrov, Andrey, Balazs, Tibor, Cseuz, Regina, Drescher, Edit, Poor, Gyula

Source: The Lancet; December 2018, Vol. 392 Issue: 10163 p2441-2451, 11p

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