Infection pre-Ad26.COV2.S-vaccination primes greater class switching and reduced CXCR5 expression by SARS-CoV-2-specific memory B cells

Authors: Robert G. E. Krause, Thandeka Moyo-Gwete, Simone I. Richardson, Zanele Makhado, Nelia P. Manamela, Tandile Hermanus, Nonhlanhla N. Mkhize, Roanne Keeton, Ntombi Benede, Mathilda Mennen, Sango Skelem, Farina Karim, Khadija Khan, Catherine Riou, Ntobeko A. B. Ntusi, Ameena Goga, Glenda Gray, Willem Hanekom, Nigel Garrett, Linda-Gail Bekker, Andreas Groll, Alex Sigal, Penny L. Moore, Wendy A. Burgers, Alasdair Leslie

Source: npj Vaccines, Vol 8, Iss 1, Pp 1-15 (2023)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2059-0105

Access URL: https://doaj.org/article/03b1ff7327134610b895e90b51a563cb

Distinct T cell polyfunctional profile in SARS-CoV-2 seronegative children associated with endemic human coronavirus cross-reactivity

Authors: Ntombi Benede, Marius B. Tincho, Avril Walters, Vennesa Subbiah, Amkele Ngomti, Richard Baguma, Claire Butters, Lina Hahnle, Mathilda Mennen, Sango Skelem, Marguerite Adriaanse, Heidi Facey-Thomas, Christiaan Scott, Jonathan Day, Timothy F. Spracklen, Strauss van Graan, Sashkia R. Balla, Thandeka Moyo-Gwete, Penny L. Moore, Rae MacGinty, Maresa Botha, Lesley Workman, Marina Johnson, David Goldblatt, Heather J. Zar, Ntobeko A.B. Ntusi, Liesl Zühlke, Kate Webb, Catherine Riou, Wendy A. Burgers, Roanne S. Keeton

Source: iScience, Vol 27, Iss 1, Pp 108728- (2024)

Subject Terms: Immunology, Immune response, Components of the immune system, Virology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004223028055; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/80c573280346449db3eab66b2620874b

Homologous Ad26.COV2.S vaccination results in reduced boosting of humoral responses in hybrid immunity, but elicits antibodies of similar magnitude regardless of prior infection.

Authors: Thandeka Moyo-Gwete, Simone I Richardson, Roanne Keeton, Tandile Hermanus, Holly Spencer, Nelia P Manamela, Frances Ayres, Zanele Makhado, Thopisang Motlou, Marius B Tincho, Ntombi Benede, Amkele Ngomti, Richard Baguma, Masego V Chauke, Mathilda Mennen, Marguerite Adriaanse, Sango Skelem, Ameena Goga, Nigel Garrett, Linda-Gail Bekker, Glenda Gray, Ntobeko A B Ntusi, Catherine Riou, Wendy A Burgers, Penny L Moore

Source: PLoS Pathogens, Vol 19, Iss 11, p e1011772 (2023)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/91047fe84ba14a82b86c46c0f2555468

Greater Disease Severity and Worse Clinical Outcomes in Patients Hospitalised with COVID-19 in Africa

Authors: Lina Hahnle, Mathilda Mennen, Freedom Gumedze, Daniel Mutithu, Marguerite Adriaanse, Daniel Egan, Simthandile Mazondwa, Rochelle Walters, Lambert Tetteh Appiah, Francisca Inofomoh, Okechukwu Ogah, Olukemi Adekanmbi, Fastone Goma, Elijah Ogola, Kieran Mwazo, Ahmed Suliman, Kavita Singh, Lana Raspail, Dorairaj Prabhakaran, Pablo Perel, Karen Sliwa, Ntobeko A. B. Ntusi

Source: Global Heart, Vol 19, Iss 1, Pp 34-34 (2024)

Subject Terms: covid-19, africa, sub-saharan africa, mortality, cardiovascular disease, Diseases of the circulatory (Cardiovascular) system, RC666-701, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://account.globalheartjournal.com/index.php/up-j-gh/article/view/1314; https://doaj.org/toc/2211-8179

Access URL: https://doaj.org/article/d337fc18ccf44bce8594d3e516f9d15d