Peripheral blood cellular dynamics of rheumatoid arthritis treatment informs about efficacy of response to disease modifying drugs

Authors: Åsa K. Hedman, Eitan Winter, Niyaz Yoosuf, Yair Benita, Louise Berg, Boel Brynedal, Lasse Folkersen, Lars Klareskog, Mateusz Maciejewski, Alexandra Sirota-Madi, Yael Spector, Daniel Ziemek, Leonid Padyukov, Shai S. Shen-Orr, Scott A. Jelinsky

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/015c0a27681d422fa2a149b768171efd

Influence of selected factors on the prevalence of cognitive disorders and depression among patients over 60 years of age

Authors: Małgorzata Koziarska-Rościszewska, Patrycja Iwan, Grzegorz Kardas, Paweł Kozarzewski, Jacek Rysz, Mateusz Maciejewski

Source: Family Medicine & Primary Care Review, Vol 24, Iss 2, Pp 134-138 (2022)

Subject Terms: depression, dementia, mental status and dementia tests, Medicine

File Description: electronic resource

Relation: https://www.termedia.pl/Influence-of-selected-factors-on-the-prevalence-of-cognitive-disorders-and-depression-among-patients-over-60-years-of-age,95,46939,1,1.html; https://doaj.org/toc/1734-3402; https://doaj.org/toc/2449-8580

Access URL: https://doaj.org/article/959f328115934674b5afc798fb75c319

Molecular signature of methotrexate response among rheumatoid arthritis patients

Authors: Boel Brynedal, Niyaz Yoosuf, Tinna Bjorg Ulfarsdottir, Daniel Ziemek, Mateusz Maciejewski, Lasse Folkersen, Helga Westerlind, Malin Müller, Peter Sahlström, Scott A. Jelinsky, Aase Hensvold, Leonid Padyukov, Nancy Vivar Pomiano, Anca Catrina, Lars Klareskog, Louise Berg

Source: Frontiers in Medicine, Vol 10 (2023)

Subject Terms: rheumatoid anhritis, treatment response, methotrexate, gene expression, flow cytometry, plasma proteins, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2023.1146353/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/75fb2c0635c442d4bc63cec8b8b58bca

What Is the Persistence to Methotrexate in Rheumatoid Arthritis, and Does Machine Learning Outperform Hypothesis‐Based Approaches to Its Prediction?

Authors: Helga Westerlind, Mateusz Maciejewski, Thomas Frisell, Scott A Jelinsky, Daniel Ziemek, Johan Askling

Source: ACR Open Rheumatology, Vol 3, Iss 7, Pp 457-463 (2021)

Subject Terms: Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/2578-5745

Access URL: https://doaj.org/article/304b99c5d174450f912549a75cca53e6

Distinct clinical phenotypes for Crohn’s disease derived from patient surveys

Authors: Tianyun Liu, Lichy Han, Mera Tilley, Lovisa Afzelius, Mateusz Maciejewski, Scott Jelinsky, Chao Tian, Matthew McIntyre, the 23andMe Research Team, Nan Bing, Kenneth Hung, Russ B. Altman

Source: BMC Gastroenterology, Vol 21, Iss 1, Pp 1-11 (2021)

Subject Terms: Crohn’s disease, Patient-reported data, Phenotypes, Subtypes, Classification, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1471-230X

Access URL: https://doaj.org/article/c3ccf1a423d24b01bd3f9a121dd5a241

Prediction of response of methotrexate in patients with rheumatoid arthritis using serum lipidomics

Authors: Mateusz Maciejewski, Caroline Sands, Nisha Nair, Stephanie Ling, Suzanne Verstappen, Kimme Hyrich, Anne Barton, Daniel Ziemek, Matthew R. Lewis, Darren Plant

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/15aaa01033fa4c62b85b8be3ce377903

Standard machine learning approaches outperform deep representation learning on phenotype prediction from transcriptomics data

Authors: Aaron M. Smith, Jonathan R. Walsh, John Long, Craig B. Davis, Peter Henstock, Martin R. Hodge, Mateusz Maciejewski, Xinmeng Jasmine Mu, Stephen Ra, Shanrong Zhao, Daniel Ziemek, Charles K. Fisher

Source: BMC Bioinformatics, Vol 21, Iss 1, Pp 1-18 (2020)

Subject Terms: Transcriptomics, RNA-seq, Normalization methods, Machine learning, Deep learning, Representation learning, Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12859-020-3427-8; https://doaj.org/toc/1471-2105

Access URL: https://doaj.org/article/4a80ce019b8d4e889e86cf97f5025413

Reverse translation of adverse event reports paves the way for de-risking preclinical off-targets

Authors: Mateusz Maciejewski, Eugen Lounkine, Steven Whitebread, Pierre Farmer, William DuMouchel, Brian K Shoichet, Laszlo Urban

Source: eLife, Vol 6 (2017)

Subject Terms: adverse drug reactions, FAERS, big data, data analysis, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/25818; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/093147f8a3444b44bec422d9105175a0

Experimental Design Strategy: Weak Reinforcement Leadsto Increased Hit Rates and Enhanced Chemical Diversity.

Authors: Mateusz Maciejewski¹, Anne Mai Wassermann¹, Meir Glick¹, Eugen Lounkine¹

Source: Journal of Chemical Information & Modeling; May2015, Vol. 55 Issue 5, p956-962, 7p