Using cloud infrastructure to facilitate data collection and conversion of HLA diagnostic data for the 18th International HLA and Immunogenetics Workshop

Authors: Matern, Benedict M., Niemann, Matthias, Nemparis, Ioannis, Schimanski, Andreas, Peereboom, Emma T. M., Kramer, Cynthia S. M., Heidt, Sebastiaan, Spierings, Eric

Source: HLA. 101(5):484-495

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100184878673.0x000001&indx=1&recIds=ETOCvdc_100184878673.0x000001

Repeated local ellipsoid protrusion supplements HLA surface characterization.

Authors: Niemann, Matthias¹ (AUTHOR) matthias.niemann@pirche.com, Matern, Benedict M.^1,2 (AUTHOR), Spierings, Eric^2,3 (AUTHOR)

Source: HLA: Immune Response Genetics. Jan2024, Vol. 103 Issue 1, p1-14. 14p.

Subject Terms: *SURFACE analysis, *ELLIPSOIDS, *MOLECULAR shapes, *WEB services, *GRAFT survival

The Value of Single-cell Technologies in Solid Organ Transplantation Studies

Authors: Peereboom, Emma T.M., Matern, Benedict M., Spierings, Eric, Geneugelijk, Kirsten

Source: Transplantation. 106(12):2325-2337

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173145728.0x000001&indx=1&recIds=ETOCvdc_100173145728.0x000001

Advancing risk stratification in kidney transplantation: integrating HLA-derived T-cell epitope and B-cell epitope matching algorithms for enhanced predictive accuracy of HLA compatibility.

Authors: Niemann, Matthias, Matern, Benedict M., Gupta, Gaurav, Tanriover, Bekir, Halleck, Fabian, Budde, Klemens, Spierings, Eric

Source: Frontiers in Immunology; 2025, p1-14, 14p

Subject Terms: PROPORTIONAL hazards models, KIDNEY transplantation, B cells, T cells, GRAFT survival

Molecular matching tools for allocation and immunosuppression optimization. Ready for primetime?

Authors: Niemann, Matthias, Matern, Benedict M.

Source: Current Opinion in Organ Transplantation; Feb2025, Vol. 30 Issue 1, p30-36, 7p

Report from the extended HLA‐DPA1 ~ promoter ~ HLA‐DPB1 haplotype of the 18th international HLA and immunogenetics workshop.

Authors: Truong, Linh^1,2 (AUTHOR) linh.truong@health.wa.gov.au, Matern, Benedict M.³ (AUTHOR), El‐Lagta, Naser¹ (AUTHOR), Mobegi, Fredrick M.¹ (AUTHOR), Askar, Medhat⁴ (AUTHOR), Ogret, Yeliz⁵ (AUTHOR), Oguz, Fatma S.⁵ (AUTHOR), Kwok, Janette⁶ (AUTHOR), D'Orsogna, Lloyd^1,2 (AUTHOR), Martinez, Patricia^1,2 (AUTHOR), Petersdorf, Effie⁷ (AUTHOR), Tilanus, Marcel G. J.⁸ (AUTHOR), De Santis, Dianne^1,2 (AUTHOR)

Source: HLA: Immune Response Genetics. Dec2023, Vol. 102 Issue 6, p690-706. 17p.

Subject Terms: *HAPLOTYPES, *HEMATOPOIETIC stem cells, *ALLELES, *GENETIC variation, *SINGLE nucleotide polymorphisms, *IMMUNOGENETICS, *STEM cell transplantation

Standard reference sequences for submission of HLA genotyping for the 18th International HLA and Immunogenetics Workshop

Authors: Matern, Benedict M., Mack, Steven J., Osoegawa, Kazutoyo, Maiers, Martin, Niemann, Matthias, Robinson, James, Heidt, Sebastiaan, Spierings, Eric

Source: HLA. 97(6):512-519

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121122038.0x000001&indx=1&recIds=ETOCvdc_100121122038.0x000001

Quantifying uncertainty of molecular mismatch introduced by mislabeled ancestry using haplotype-based HLA genotype imputation.

Authors: Matern, Benedict M., Spierings, Eric, Bandstra, Selle, Madbouly, Abeer, Schaub, Stefan, Weimer, Eric T., Niemann, Matthias

Source: Frontiers in Genetics; 2024, p1-13, 13p

Subject Terms: AMINO acid sequence, HAPLOTYPES, PROTEIN structure, GENOTYPES, LOCUS (Genetics), T cells

Paternal HLA‐Derived Epitopes and Live Birth in Secondary Recurrent Pregnancy Loss: New Insights From a Clinical Trial.

Authors: Krog, Maria Christine, Peereboom, Emma T. M., Geneugelijk, Kirsten, Matern, Benedict M., Kolte, Astrid Marie, Christiansen, Ole Bjarne, Steffensen, Rudi, Nielsen, Henriette Svarre, Spierings, Eric

Source: HLA: Immune Response Genetics; Oct2024, Vol. 104 Issue 4, p1-13, 13p

Subject Terms: RECURRENT miscarriage, MISCARRIAGE, RANDOMIZED controlled trials, ANTIBODY formation, EPITOPES, PREGNANCY

Long-Read Nanopore Sequencing Validated for Human Leukocyte Antigen Class I Typing in Routine Diagnostics

Authors: Matern, Benedict M., Olieslagers, Timo I., Groeneweg, Mathijs, Duygu, Burcu, Wieten, Lotte, Tilanus, Marcel G.J., Voorter, Christina E.M.

Source: In The Journal of Molecular Diagnostics July 2020 22(7):912-919

Specific amino acid patterns define split specificities of HLA-B15 antigens enabling conversion from DNA-based typing to serological equivalents

Authors: Duygu, Burcu, Matern, Benedict M., Wieten, Lotte, Voorter, Christina E.M., Tilanus, Marcel G.J.

Source: Immunogenetics. 72(6-7):339-346

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167908179.0x000001&indx=1&recIds=ETOCvdc_100167908179.0x000001

PIRCHE application major versions 3 and 4 lead to equivalent T cell epitope mismatch scores in solid organ and stem cell transplantation modules

Authors: Matern, Benedict M., Niemann, Matthias

Source: In Human Immunology May 2024 85(3)

Snowflake: A deep learning-based human leukocyte antigen matching algorithm considering allele-specific surface accessibility.

Authors: Niemann, Matthias, Matern, Benedict M., Spierings, Eric

Source: Frontiers in Immunology; 7/29/2022, Vol. 13, p1-13, 13p

Subject Terms: HLA histocompatibility antigens, AMINO acid sequence, RECURRENT neural networks, SNOWFLAKES, PEPTIDES

Peptides Derived From Mismatched Paternal Human Leukocyte Antigen Predicted to Be Presented by HLA-DRB1, -DRB3/4/5, -DQ, and -DP Induce Child-Specific Antibodies in Pregnant Women.

Authors: Niemann, Matthias, Matern, Benedict M., Spierings, Eric, Schaub, Stefan, Hönger, Gideon

Source: Frontiers in Immunology; 12/21/2021, Vol. 12, p1-12, 12p

Subject Terms: HLA histocompatibility antigens, PREGNANT women, ANTIGENS, IMMUNOGLOBULINS, PEPTIDES, IMMUNE response

T-Cell Epitopes Shared Between Immunizing HLA and Donor HLA Associate With Graft Failure After Kidney Transplantation.

Authors: Peereboom, Emma T. M., Matern, Benedict M., Tomosugi, Toshihide, Niemann, Matthias, Drylewicz, Julia, Joosten, Irma, Allebes, Wil A., van der Meer, Arnold, Hilbrands, Luuk B., Baas, Marije C., van Reekum, Franka E., Verhaar, Marianne C., Kamburova, Elena G., Seelen, Marc A. J., Sanders, Jan Stephan, Hepkema, Bouke G., Lambeck, Annechien J., Bungener, Laura B., Roozendaal, Caroline, Tilanus, Marcel G. J.

Source: Frontiers in Immunology; 11/18/2021, Vol. 12, p1-13, 13p

Subject Terms: T cells, KIDNEY transplantation, EPITOPES, KIDNEY failure, BIOMARKERS, PSYCHONEUROIMMUNOLOGY

The MHC class I MICAgene is a histocompatibility antigen in kidney transplantation

Authors: Carapito, Raphael, Aouadi, Ismail, Verniquet, Martin, Untrau, Meiggie, Pichot, Angélique, Beaudrey, Thomas, Bassand, Xavier, Meyer, Sébastien, Faucher, Loic, Posson, Juliane, Morlon, Aurore, Kotova, Irina, Delbos, Florent, Walencik, Alexandre, Aarnink, Alice, Kennel, Anne, Suberbielle, Caroline, Taupin, Jean-Luc, Matern, Benedict M., Spierings, Eric, Congy-Jolivet, Nicolas, Essaydi, Arnaud, Perrin, Peggy, Blancher, Antoine, Charron, Dominique, Cereb, Nezih, Maumy-Bertrand, Myriam, Bertrand, Frédéric, Garrigue, Valérie, Pernin, Vincent, Weekers, Laurent, Naesens, Maarten, Kamar, Nassim, Legendre, Christophe, Glotz, Denis, Caillard, Sophie, Ladrière, Marc, Giral, Magali, Anglicheau, Dany, Süsal, Caner, Bahram, Seiamak

Source: Nature Medicine; 20220101, Issue: Preprints p1-10, 10p

OR25. The highly polymorphic HLA-DRA Gene: conserved and diverse regions within the HLA-DRA gene imply haplotypes of DRA∼DRB3/4/5∼DRB1∼DQB1

Authors: Matern, Benedict M., Olieslagers, Timo I., de Rooij, Laura, Voorter, Christien E., Groeneweg, Mathijs, Tilanus, Marcel G.

Source: Human immunology. 79(S):30-30

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100081651788.0x000001&indx=1&recIds=ETOCvdc_100081651788.0x000001

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