Carboplatin in combination with etoposide for advanced small cell lung cancer complicated with idiopathic interstitial pneumonia: a single-arm phase II study

Authors: Masaru Matsumoto, Yuji Minegishi, Katsuyuki Higa, Aya Fukuizumi, Naomi Onda, Susumu Takeuchi, Akihiko Miyanaga, Akihiko Gemma, Masahiro Seike

Source: BMC Pulmonary Medicine, Vol 25, Iss 1, Pp 1-8 (2025)

Subject Terms: Idiopathic interstitial pneumonia, Idiopathic pulmonary fibrosis, Acute exacerbation, Chemotherapy, Small cell lung cancer, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2466

Access URL: https://doaj.org/article/ccb942086bbf46839433097a5902f93f

Bortezomib induces Rho-dependent hyperpermeability of endothelial cells synergistically with inflammatory mediators

Authors: Shunichi Nishima, Takeru Kashiwada, Yoshinobu Saito, Shinya Yuge, Tomohiro Ishii, Kuniko Matsuda, Koichiro Kamio, Masahiro Seike, Shigetomo Fukuhara, Akihiko Gemma

Source: BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-11 (2024)

Subject Terms: Actin fibers, Bortezomib, Endothelial permeability, Drug-induced lung disease, Proteasome inhibitors, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2466

Access URL: https://doaj.org/article/1c6a0c18ae5847558744f57deab3e96d

Transbronchial lung cryobiopsy for interstitial lung disease: early experience, learning curve, and the impact of sedation on complication rates at a single centre in Japan

Authors: Shota Kaburaki, Toru Tanaka, Koichiro Kamio, Yosuke Tanaka, Kazuo Kasahara, Masahiro Seike

Source: BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-8 (2024)

Subject Terms: Transbronchial lung cryobiopsy, Interstitial lung disease, Cumulative sum learning curve analysis, Sedation, Fentanyl, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2466

Access URL: https://doaj.org/article/9d5408acd2134bbf9128e5dcc3fed31c

Allergic bronchopulmonary mycosis induced by pembrolizumab for bladder cancer: A case report

Authors: Hiroki Iida, Kenichiro Atsumi, Naohiro Kadoma, Sae Takashima, Yukari Shirakura, Ayana Suzuki, Kakeru Hisakane, Ryo Matsuoka, Koji Nagata, Masahiro Seike, Takashi Hirose

Source: Respiratory Medicine Case Reports, Vol 54, Iss , Pp 102179- (2025)

Subject Terms: Aspergillosis, Allergic bronchopulmonary, Pembrolizumab, Urinary bladder neoplasms, Immune checkpoint inhibitors, Drug-related side effects and adverse reactions, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213007125000152; https://doaj.org/toc/2213-0071

Access URL: https://doaj.org/article/276d488ebc7546839777808553f93d25

Treatment patterns and clinical outcomes of resectable clinical stage III non‐small cell lung cancer in a Japanese real‐world setting: Surgery cohort analysis of the SOLUTION study

Authors: Masahiro Tsuboi, Haruyasu Murakami, Hideyuki Harada, Tomotaka Sobue, Tomohiro Kato, Shinji Atagi, Takaaki Tokito, Tadashi Mio, Hirofumi Adachi, Toshiyuki Kozuki, Takashi Sone, Masahiro Seike, Shinichi Toyooka, Hiroshi Kitagawa, Ryo Koto, Satoshi Yamazaki, Hidehito Horinouchi

Source: Thoracic Cancer, Vol 15, Iss 20, Pp 1541-1552 (2024)

Subject Terms: disease‐free survival, perioperative therapy, resectability, stage III non‐small cell lung cancer, surgery, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1759-7706; https://doaj.org/toc/1759-7714

Access URL: https://doaj.org/article/301b08279edf4e2cb9aa89a30fb1a6a3

Ixekizumab-induced interstitial lung disease: a case report confirmed by transbronchial lung cryobiopsy

Authors: Shota Kaburaki, Naoko Okada, Toru Tanaka, Koichiro Kamio, Yosuke Tanaka, Yasuhiro Terasaki, Kazuo Kasahara, Masahiro Seike

Source: Journal of Dermatological Treatment, Vol 35, Iss 1 (2024)

Subject Terms: Transbronchial lung cryobiopsy, drug-induced interstitial lung disease, ixekizumab, psoriasis, Dermatology, RL1-803

File Description: electronic resource

Relation: https://doaj.org/toc/0954-6634; https://doaj.org/toc/1471-1753

Access URL: https://doaj.org/article/9e7dee6b70664df3abc6d15e5d76d714

The Histopathology of Abemaciclib-Induced Interstitial Lung Disease: A First Case Report With Transbronchial Lung Cryobiopsy

Authors: Shota Kaburaki, Toru Tanaka, Akari Murata, Koichiro Kamio, Yosuke Tanaka, Yasuhiro Terasaki, Kazuo Kasahara, Masahiro Seike

Source: Breast Cancer: Basic and Clinical Research, Vol 18 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1178-2234

Access URL: https://doaj.org/article/1dcc2a6e69fe4285b2fc2511fbe6fabd

Interstitial lung disease with prolonged fever that occurred during long-term administration of olaparib in a 74-year-old ovarian cancer patient: Radiological features and considerations for preventing delayed diagnosis

Authors: Yoshinobu Saito, Rei Yamaguchi, Takahiro Suzuki, Junpei Sato, Nobuhiko Nishijima, Sho Saito, Junichi Aoyama, Namiko Taniuchi, Masahiro Seike, Noriyuki Katsumata

Source: Radiology Case Reports, Vol 19, Iss 6, Pp 2100-2105 (2024)

Subject Terms: Olaparib, Interstitial lung disease, Fever, Computed tomography, Ground-glass opacity, Centrilobular nodule, Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1930043324001559; https://doaj.org/toc/1930-0433

Access URL: https://doaj.org/article/a50e3c7f0b254ac0a2f107fd42ca68fb

IgA vasculitis induced by carboplatin + nab-paclitaxel + pembrolizumab in a patient with advanced lung squamous cell carcinoma: a case report

Authors: Yuto Terashima, Masaru Matsumoto, Saeko Ozaki, Michiko Nakagawa, Shun Nakagome, Yasuhiro Terasaki, Hiroki Iida, Ryotaro Mitsugi, Eri Kuramochi, Naoko Okada, Tomoyasu Inoue, Satoru Matsuki, Shingo Kitagawa, Aya Fukuizumi, Naomi Onda, Susumu Takeuchi, Akihiko Miyanaga, Kazuo Kasahara, Masahiro Seike

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: IgA vasculitis, immune-related adverse event, immune checkpoint inhibitor, pembrolizumab, non-small-cell lung cancer, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1370972/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/356b84b7dca94049a8e2fdbe30a368df

Novel evaluation of pulmonary hypertension associated with chronic lung disease using perfusion SPECT/CT: A pilot study

Authors: Kenichiro Atsumi, Yoshimitsu Fukushima, Yosuke Tanaka, Shunichi Nishima, Toru Tanaka, Masahiro Seike, Yoshiaki Kubota, Hiroshi Kimura

Source: Pulmonary Circulation, Vol 14, Iss 3, Pp n/a-n/a (2024)

Subject Terms: perfusion imaging, phosphodiesterase 5 inhibitors, pulmonary hypertension, single‐photon emission computed tomography/computed tomography, vasodilator agents, Diseases of the circulatory (Cardiovascular) system, RC666-701, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/2045-8940

Access URL: https://doaj.org/article/5bdf618ccc434a65bfa33df93df26975

Exploring effective biomarkers and potential immune related gene in small cell lung cancer

Authors: Yang Yunchu, Akihiko Miyanaga, Kuniko Matsuda, Koichiro Kamio, Masahiro Seike

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/97fd13128be2457faeead90f866ebbb3

Clinical course of COPD patients with exercise-induced elevation of pulmonary artery pressure or less severe pulmonary hypertension presenting with respiratory symptoms and the impact of bosentan intervention—prospective, single-center, randomized, parallel-group study

Authors: Takeru Kashiwada, Yosuke Tanaka, Toru Tanaka, Tetsuya Okano, Yoshinobu Saito, Masahiro Seike, Mitsunori Hino, Hiroshi Kimura, Akihiko Gemma

Source: BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-15 (2024)

Subject Terms: Pulmonary hypertension, COPD, Right heart catheterization, Echocardiography, Endothelin receptor antagonists, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2466

Access URL: https://doaj.org/article/4eec458e48824e8aad40b58239dfee83

Induction of resistance to neurotrophic tropomyosin‐receptor kinase inhibitors by HMGCS2 via a mevalonate pathway

Authors: Yasuhiro Kato, Masaru Matsumoto, Natsuki Takano, Mariko Hirao, Kuniko Matsuda, Takehiro Tozuka, Naomi Onda, Shinji Nakamichi, Susumu Takeuchi, Akihiko Miyanaga, Rintaro Noro, Akihiko Gemma, Masahiro Seike

Source: Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)

Subject Terms: HMGCS2, mevalonate pathway, NTRK‐TKI, resistance mechanism, statin, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/7e17ba81b3294778a9a44409ba4acb39

Combination of plasma MMPs and PD-1-binding soluble PD-L1 predicts recurrence in gastric cancer and the efficacy of immune checkpoint inhibitors in non-small cell lung cancer

Authors: Fumihiko Ando, Takeru Kashiwada, Shoko Kuroda, Takenori Fujii, Ryotaro Takano, Yoshishige Miyabe, Shinobu Kunugi, Takashi Sakatani, Akihiko Miyanaga, Tomoko Asatsuma-Okumura, Masaaki Hashiguchi, Yoshikazu Kanazawa, Ryuji Ohashi, Hiroshi Yoshida, Masahiro Seike, Akihiko Gemma, Yoshiko Iwai

Source: Frontiers in Pharmacology, Vol 15 (2024)

Subject Terms: soluble PD-L1, MMP13, tumor microenvironment, extracellular matrix integrity, T cell response, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1384731/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/7a6226e84bee43938e923417f736a470

Lysosomal degradation of PD-L1 is associated with immune-related adverse events during anti-PD-L1 immunotherapy in NSCLC patients

Authors: Takeru Kashiwada, Ryotaro Takano, Fumihiko Ando, Shoko Kuroda, Yoshishige Miyabe, Ryuji Owada, Akihiko Miyanaga, Tomoko Asatsuma-Okumura, Masaaki Hashiguchi, Yoshikazu Kanazawa, Hiroshi Yoshida, Masahiro Seike, Akihiko Gemma, Yoshiko Iwai

Source: Frontiers in Pharmacology, Vol 15 (2024)

Subject Terms: soluble PD-L1, inflammation, macrophage, lysosomal degradation, immune-related adverse event, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1384733/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/9f25c0d48b8e40b28822e0ee50aa0364

Immunotherapy With Radiotherapy for Brain Metastases in Patients With NSCLC: NEJ060

Authors: Takehiro Tozuka, MD, Yuji Minegishi, MD, PhD, Ou Yamaguchi, MD, PhD, Kana Watanabe, MD, Yukihiro Toi, MD, Ryota Saito, MD, PhD, Yoshiaki Nagai, MD, PhD, Yosuke Tamura, MD, PhD, Tetsuaki Shoji, MD, PhD, Haruka Odagiri, MD, Noriyuki Ebi, MD, Kosuke Sakai, MD, PhD, Nobuhiro Kanaji, MD, PhD, Makoto Izumi, MD, Sayo Soda, MD, PhD, Satoshi Watanabe, MD, PhD, Satoshi Morita, PhD, Kunihiko Kobayashi, MD, PhD, Masahiro Seike, MD, PhD

Source: JTO Clinical and Research Reports, Vol 5, Iss 4, Pp 100655- (2024)

Subject Terms: Immunotherapy, Brain metastases, Non–small cell lung cancer, Radiotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666364324000250; https://doaj.org/toc/2666-3643

Access URL: https://doaj.org/article/266c2a21ca60472ab272511e35e74652

Phosphoproteomic Analysis Identified Mutual Phosphorylation of FAK and Src as a Mechanism of Osimertinib Resistance in EGFR-Mutant Lung Cancer

Authors: Takehiro Tozuka, MD, Rintaro Noro, MD, PhD, Keisuke Yoshida, PhD, Satoshi Takahashi, MD, PhD, Mariko Hirao, MD, Kuniko Matsuda, MD, Yasuhiro Kato, MD, Shinji Nakamichi, MD, PhD, Susumu Takeuchi, MD, PhD, Masaru Matsumoto, MD, PhD, Akihiko Miyanaga, MD, PhD, Shinobu Kunugi, MD, PhD, Kazufumi Honda, DDS, PhD, Jun Adachi, PhD, Masahiro Seike, MD, PhD

Source: JTO Clinical and Research Reports, Vol 5, Iss 4, Pp 100668- (2024)

Subject Terms: Non–small cell lung cancer, EGFR, Osimertinib, Resistant, Src, FAK, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666364324000389; https://doaj.org/toc/2666-3643

Access URL: https://doaj.org/article/28ffabd2f77f47d7942680f03c8b460c

Osimertinib early dose reduction as a risk to brain metastasis control in EGFR‐mutant non‐small cell lung cancer

Authors: Takehiro Tozuka, Rintaro Noro, Akihiko Miyanaga, Shinji Nakamichi, Susumu Takeuchi, Masaru Matsumoto, Kaoru Kubota, Kazuo Kasahara, Masahiro Seike

Source: Cancer Medicine, Vol 12, Iss 17, Pp 17731-17739 (2023)

Subject Terms: brain metastases, dose reduction, non‐small cell lung cancer, osimertinib, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/54843e42ca924dc5a5ec2837bb1b4e48

Platinum‐combination chemotherapy with or without immune‐checkpoint inhibitor in patients with postoperative recurrent non‐small cell lung cancer previously treated with adjuvant platinum‐doublet chemotherapy: A multicenter retrospective study

Authors: Kakeru Hisakane, Takehiro Tozuka, Satoshi Takahashi, Namiko Taniuchi, Nobuhiko Nishijima, Kenichiro Atsumi, Tetsuya Okano, Masahiro Seike, Takashi Hirose

Source: Thoracic Cancer, Vol 14, Iss 21, Pp 2069-2076 (2023)

Subject Terms: immune‐checkpoint inhibitor, non‐small cell lung cancer, platinum‐combination chemotherapy, postoperative recurrence, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1759-7706; https://doaj.org/toc/1759-7714

Access URL: https://doaj.org/article/39a79a5f257547309326abdda8af2a13

Improvement in idiopathic interstitial pneumonia by adding macitentan to a patient unresponsive to nintedanib

Authors: Yosuke Tanaka, Shota Kaburaki, Toru Tanaka, Koichiro Kamio, Tetsuya Okano, Masahiro Seike

Source: Respiratory Medicine Case Reports, Vol 50, Iss , Pp 102058- (2024)

Subject Terms: Macitentan, Endothelin receptor antagonist, Interstitial pneumonia, Pulmonary hypertension, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213007124000819; https://doaj.org/toc/2213-0071

Access URL: https://doaj.org/article/3b5754b9a6414f399b55a65b8adb0a04