Interrelationships between polygenic risk scores, cognition, symptoms, and functioning in first-episode psychosis: A network analysis approach

Authors: Gil-Berrozpe, Gustavo J. ^{a, b, 1}, Segura, Alex G. ^{c, 1}, Sánchez-Torres, Ana M. ^{b, d}, Amoretti, Silvia ^{e, f, g}, Giné-Servén, Eloi ^h, Vieta, Eduard ^{c, f, i, j}, Mezquida, Gisela ^{f, j, k, l}, Lobo, Antonio ^{f, m}, Gonzalez-Pinto, Ana ^{f, n}, Andreu-Bernabeu, Alvaro ^{f, o, p}, Roldán, Alexandra ^{f, q}, Forte, Maria Florencia ^{c, f, i, j}, Castro, Josefina ^{f, j, o, r}, Bergé, Daniel ^{f, s}, Rodríguez, Natalia ^{j, k}, Ballesteros, Alejandro ^t, Mas, Sergi ^{f, j, k, ⁎⁎}, Cuesta, Manuel J. ^{a, b, ⁎}, Bernardo, Miquel ^{f, i, j, l}

Source: In European Neuropsychopharmacology March 2025 92:52-61

Methylation profile scores of environmental exposures and risk of relapse after a first episode of schizophrenia

Authors: Segura, Alex-González ^{a, #}, Prohens, Llucia ^{b, #}, Julià, Laura ^b, Amoretti, Silvia ^{b, c, d, e}, RIbero, Maria ^{e, f, g}, Pino-Camacho, Laura ^{e, h}, Cano-Escalera, Guillermo ^{e, i}, Mane, Anna ^{e, j}, Rodriguez-Jimenez, Roberto ^{e, k, l}, Roldan, Alexandra ^{e, m}, Sarró, Salvador ^{e, n}, Ibañez, Angela ^{e, o}, Usall, Judith ^p, Lobo, Antonio ^{e, q}, Garcia-Rizo, Clemente ^{c, e}, Cuesta, Manuel Jesus ^{e, f, g}, Parellada, Mara ^{e, h}, González-Pinto, Ana ^{e, i}, Berrocoso, Esther ^{e, r}, Bernardo, Miquel ^{c, e, ⁎}, Mas, Sergi ^{b, e, ⁎⁎}, Rodríguez, Natalia ^{b, e}, Perez-Ramos, Anaid ^c, Salmeron, Sergi ^c, González-Peñas, Javier ^{e, h}, Gurriarán, Xaquín ^{e, h}, Farré, Adriana ^{e, m}, Pousa, Esther ^{e, m}, Zorrilla, Iñaki ^{e, i}, Mar-Barrutia, Lorea ^{e, i}, Trabsa, Amira ^{e, j}, Martinez, Laura ^{e, j}, Sánchez-Cabezudo, Ángeles ^l, Jiménez-López, Estela ^{e, s}, Pomarol-Clotet, Edith ^{e, n}, Salvador, Raymond ^{e, n}, Butjosa, Anna ^{e, p}, Elena, Rubio-Abadal ^p, Moreno-Izco, Lucía ^{e, f, g}, Torres, Ana M. Sánchez ^{e, f, g}, Saiz, Jeronimo ^o, León-Quismondo, Leticia ^o, Rivero, Olga ^{e, t}, González-Blanco, Leticia ^{e, u}, De-la-Cámara, Concepción ^{e, q, v}

Source: In European Neuropsychopharmacology May 2025 94:4-15

Numerical Investigation of the Bias-path Model for the Photocurrent in Photoconductive Antennas

Authors: Mas, Sergi, Lopez-Menchon, Hector, Santos, Maria C.

Source: 2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz) Infrared, Millimeter and Terahertz Waves (IRMMW-THz),2022 47th International Conference on. :1-2 Aug, 2022

Relation: 2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz)

Effects of the PAM of mGluR2, JNJ-46356479, on brain apoptotic protein levels in a mouse model of schizophrenia

Authors: Olivares-Berjaga, David, Martínez-Pinteño, Albert, Rodríguez, Natalia, Madero, Santiago, Prohens, Llucía, Martínez-Serrano, Irene, Mas, Sergi, Morén, Constanza, Parellada, Eduard, Gassó, Patricia

Source: In Progress in Neuropsychopharmacology & Biological Psychiatry 20 April 2024 131

Polygenic risk scores mediating functioning outcomes through cognitive and clinical features in youth at family risk and controls

Authors: Segura, Alex G, Serna, Elena de la, Sugranyes, Gisela, Baeza, Inmaculada, Valli, Isabel, Martínez-Serrano, Irene, Díaz-Caneja, Covadonga M, Andreu-Bernabeu, Álvaro, Moreno, Dolores M, Gassó, Patricia, Rodríguez, Natalia, Martínez-Pinteño, Albert, Prohens, Llucia, Torrent, Carla, García-Rizo, Clemente, Mas, Sergi, Castro-Fornieles, Josefina

Source: In European Neuropsychopharmacology April 2024 81:28-37

Gene expression imputation provides clinical and biological insights into treatment-resistant schizophrenia polygenic risk

Authors: Prohens, Llucia, Rodríguez, Natalia, Segura, Àlex-Gonzàlez, Martínez-Pinteño, Albert, Olivares-Berjaga, David, Martínez, Irene, González, Aitor, Mezquida, Gisela, Parellada, Mara, Cuesta, Manuel J, Bernardo, Miquel, Gassó, Patricia, Mas, Sergi

Source: In Psychiatry Research February 2024 332

Obstetric complications and genetic risk for schizophrenia: Differential role of antenatal and perinatal events in first episode psychosis

Authors: Valli, Isabel, Gonzalez Segura, Alex, Verdolini, Norma, Garcia‐Rizo, Clemente, Berge, Daniel, Baeza, Inmaculada, Cuesta, Manuel J., Gonzalez‐Pinto, Ana, Lobo, Antonio, Martinez‐Aran, Anabel, Mezquida, Gisela, Pina‐Camacho, Laura, Roldan Bejarano, Alexandra, Mas, Sergi, McGuire, Philip, Bernardo, Miquel, Vieta, Eduard, Amoretti, Silvia, Avila Parcet, Aina, Balanzá‐Martínez, Vicent, Borras, Roger, Butjosa, Anna, Castro‐Fornieles, Josefina, De‐la‐Cámara, Concepción, De la Serna, Elena, Etxeandia‐Pradera, Jon‐Inaki, Forte, Maria Florencia, García‐Portilla, Paz, González, Jairo M., González‐Blanco, Leticia, Gonzalez‐Ortega, Itxaso, Ibañez, Angela, Madero, Santiago, Martínez‐Sadurni, Laura, Nacher, Juan, Panadero, Rocío, Pomarol Clotet, Edith, Fatjó‐Vilas, Mar, Rodriguez‐Jimenez, Roberto, Ruiz, Pedro, Sanchez‐Pastor, Luis, Segarra Echevarría, Rafael, Sánchez‐Torres, Ana M., Selma Gonzalez, Judith, Trabsa, Amira, Urbiola, Elena, Zabala Rabadán, Arantzazu, Zorrilla, Iñaki

Source: Acta psychiatrica Scandinavica. 148(1):81-90

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185695788.0x000001&indx=1&recIds=ETOCvdc_100185695788.0x000001

Genetic and Structural Brain Correlates of Cognitive Subtypes Across Youth at Family Risk for Schizophrenia and Bipolar Disorder

Authors: Valli, Isabel, De la Serna, Elena, Segura, Alex G., Pariente, Jose C., Calvet-Mirabent, Angels, Borras, Roger, Ilzarbe, Daniel, Moreno, Dolores, Martín-Martínez, Nuria, Baeza, Inmaculada, Rosa-Justicia, Mireia, Garcia-Rizo, Clemente, Díaz-Caneja, Covadonga M., Crossley, Nicolas A., Young, Allan H., Vieta, Eduard, Mas, Sergi, Castro-Fornieles, Josefina, Sugranyes, Gisela

Source: Journal of the American Academy of Child & Adolescent Psychiatry. 62(1):74-83

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178142215.0x000001&indx=1&recIds=ETOCvdc_100178142215.0x000001

The polygenic basis of relapse after a first episode of schizophrenia

Authors: Segura, Àlex-González, Prohens, Llucia, Gassó, Patricia, Rodríguez, Natalia, Garcia-Rizo, Clemente, Moreno-Izco, Lucía, Andreu-Bernabeu, Álvaro, Zorrilla, Iñaki, Mane, Anna, Rodriguez-Jimenez, Roberto, Roldán, Alexandra, Sarró, Salvador, Ibáñez, Ángela, Usall, Judith, Sáiz, Pilar A, Cuesta, Manuel J., Parellada, Mara, González-Pinto, Ana, Berrocoso, Ester, Bernardo, Miquel, Mas, Sergi, Mezquida, Gisela, Arbelo, Néstor, De Matteis, Mario, Galvañ, Joaquín, Duque Guerra, Alejandra, Arias i Queralt, Laia, Perez-Bacigalupe, Maria, Gonzalez-Ortega, Itxaso, Toll, Alba, Casanovas, Francesc, Sanchez-Pastor, Luis, Valtueña, Mercedes, Pomarol-Clotet, Edith, García-León, Maria Ángeles, Butjosa, Ana, Rubio-Abadal, Elena, Ribeiro, María, López-Ilundain, Jose M., Saiz-Ruiz, Jeronimo, León-Quismondo, Luis, Rivero, Olga, Ruiz, Pedro, Echevarría, Rafael Segarra, García-Portilla, M. Paz

Source: In European Neuropsychopharmacology October 2023 75:80-92

First babies conceived with Automated Intracytoplasmic Sperm Injection

Authors: Costa-Borges, Nuno, Munné, Santiago, Albó, Eduard, Mas, Sergi, Castelló, Carolina, Giralt, Guillem, Lu, Zhuo, Chau, Charles, Acacio, Mònica, Mestres, Enric, Matia, Queralt, Marquès, Laura, Rius, Mariona, Márquez, Carmen, Vanrell, Ivette, Pujol, Aïda, Mataró, Daniel, Seth-Smith, Michelle, Mollinedo, Luis, Calderón, Gloria, Zhang, John

Source: In Reproductive BioMedicine Online September 2023 47(3)

Exploration of cannabis use and polygenic risk scores on the psychotic symptom progression of a FEP cohort

Authors: Segura, Alex G, Mané, Anna, Prohens, Llucia, Rodriguez, Natalia, Mezquida, Gisela, Cuesta, Manuel J, Vieta, Eduard, Amoretti, Silvia, Lobo, Antonio, González-Pinto, Ana, Diaz-Caneja, Covadonga M, Bejarano, Alexandra Roldán, Jimenez, Esther, Baeza, Immaculada, Legido, Teresa, Saiz-Ruiz, Jeronimo, Bernardo, Miguel, Mas, Sergi

Source: In Psychiatry Research July 2023 325

Identifying risk factors for predominant negative symptoms from early stages in schizophrenia: A longitudinal and sex-specific study in first-episode schizophrenia patients

Authors: Mezquida, Gisela, Amoretti, Silvia, Bioque, Miquel, García-Rizo, Clemente, Sánchez-Torres, Ana M., Pina-Camacho, Laura, Lopez-Pena, Purificación, Mané, Anna, Rodriguez-Jimenez, Roberto, Corripio, Iluminada, Sarró, Salvador, Ibañez, Angela, Usall, Judith, García-Portilla, María Paz, Vieta, Eduard, Mas, Sergi, Cuesta, Manuel J., Parellada, Mara, González-Pinto, Ana, Berrocoso, Esther, Bernardo, Miguel

Source: In Revista de psiquiatría y salud mental (Barcelona) January 2023

Metabolic polygenic risk scores effect on antipsychotic-induced metabolic dysregulation: A longitudinal study in a first episode psychosis cohort

Authors: Segura, Àlex G., Martínez-Pinteño, Albert, Gassó, Patricia, Rodríguez, Natalia, Bioque, Miquel, Cuesta, Manuel J., González-Peñas, Javier, García-Rizo, Clemente, Lobo, Antonio, González-Pinto, Ana, García-Alcón, Alicia, Roldán, Alexandra, Vieta, Eduard, Castro-Fornieles, Josefina, Mané, Anna, Saiz, Jeronimo, Bernardo, Miguel, Mas, Sergi

Source: Schizophrenia research. 244:101-110

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165931143.0x000001&indx=1&recIds=ETOCvdc_100165931143.0x000001

Clinical and treatment predictors of relapse during a three-year follow-up of a cohort of first episodes of schizophrenia

Authors: Bioque, Miquel, Mezquida, Gisela, Amoretti, Sílvia, García-Rizo, Clemente, López-Ilundain, Jose M., Diaz-Caneja, Covadonga M., Zorrilla, Iñaki, Mané, Anna, Rodriguez-Jimenez, Roberto, Corripio, Iluminada, Pomarol-Clotet, Edith, Ibáñez, Ángela, Usall, Judith, Contreras, Fernando, Mas, Sergi, Vázquez-Bourgon, Javier, Cuesta, Manuel J., Parellada, Mara, González-Pinto, Ana, Hidalgo-Figueroa, María, Bernardo, Miquel

Source: Schizophrenia research. 243:32-42

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164939541.0x000001&indx=1&recIds=ETOCvdc_100164939541.0x000001

The role of BDNF and NGF plasma levels in first-episode schizophrenia: A longitudinal study

Authors: Martínez-Pinteño, Albert, Mezquida, Gisela, Bioque, Miquel, López-Ilundain, Jose M, Andreu-Bernabeu, Álvaro, Zorrilla, Iñaki, Mané, Anna, Rodríguez-Jiménez, Roberto, Corripio, Iluminada, Sarró, Salvador, Ibáñez, Ángela, Usall, Judith, Rivero, Olga, Gassó, Patricia, Leza, Juan Carlos, Cuesta, Manuel J, Parellada, Mara, González-Pinto, Ana, Berrocoso, Esther, Mas, Sergi, Bernardo, Miguel

Source: European neuropsychopharmacology. 57:105-117

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100159057561.0x000001&indx=1&recIds=ETOCvdc_100159057561.0x000001

Applied pharmacogenetics to predict response to treatment of first psychotic episode: study protocol.

Authors: Mas, Sergi, Julià, Laura, Cuesta, Manuel J., Crespo-Facorro, Benedicto, Vázquez-Bourgon, Javier, Spuch, Carlos, Gonzalez-Pinto, Ana, Ibañez, Angela, Usall, Judith, Romero-López-Alberca, Cristina, Catalan, Ana, Mané, Anna, Bernardo, Miquel

Source: Frontiers in Psychiatry; 2025, p1-12, 12p

Subject Terms: INDIVIDUALIZED medicine, PHARMACOGENOMICS, TREATMENT effectiveness, PHENOTYPES, PREDICTION models

Effectiveness of positive allosteric modulators of metabotropic glutamate receptor 2/3 (mGluR2/3) in animal models of schizophrenia.

Authors: Olivares-Berjaga, David, Martínez-Pinteño, Albert, Rodríguez, Natalia, Mas, Sergi, Morén, Constanza, Parellada, Eduard, Gassó, Patricia

Source: Translational Psychiatry; 1/14/2025, Vol. 15 Issue 1, p1-14, 14p

The role of BDNF and NGF plasma levels in first-episode schizophrenia: A longitudinal study

Authors: Amoretti, S, Morén, C, Urbiola, E, González-Peñas, J, Roldán, A, Catalán, A, González-Ortega, I, Toll, A, Legido, T, Sanchez-Pastor, L, Dompablo, M, Pomarol-Clotet, E, R, Landín-Romero, Butjosa, A, Rubio, E, Lorente-OmeñacaR, Ribeiro, M, López-Torres, I, León-Quismondo, L, Nácher, J, Contretas, F, Lobo, A, Gutiérrez-Fraile, M, Sáiz, PA, Martínez-Pinteño, Albert, Mezquida, Gisela, Bioque, Miquel, López-Ilundain, Jose M, Andreu-Bernabeu, Álvaro, Zorrilla, Iñaki, Mané, Anna, Rodríguez-Jiménez, Roberto, Corripio, Iluminada, Sarró, Salvador, Ibáñez, Ángela, Usall, Judith, Rivero, Olga, Gassó, Patricia, Leza, Juan Carlos, Cuesta, Manuel J, Parellada, Mara, González-Pinto, Ana, Berrocoso, Esther, Mas, Sergi, Bernardo, Miguel

Source: In European Neuropsychopharmacology April 2022 57:105-117

Assessing cognitive reserve outcomes and biomarkers in first episode of psychosis: Rationale, objectives, protocol and preliminary results of the CRASH Project

Authors: Bernardo, Miquel, Anmella, Gerard, Verdolini, Norma, Saiz-Masvidal, Cristina, Casals, Sonia, Contreras, Fernando, Garrido, Ignasi, Pérez, Ferran, Safont, Gemma, Mas, Sergi, Rodriguez, Natalia, Meseguer, Ana, Pons-Cabrera, Maria Teresa, Vieta, Eduard, Amoretti, Silvia

Source: In Revista de psiquiatría y salud mental (Barcelona) March 2022

The positive allosteric modulator of the mGlu2 receptor JNJ-46356479 partially improves neuropathological deficits and schizophrenia-like behaviors in a postnatal ketamine mice model

Authors: Martínez-Pinteño, Albert, García-Cerro, Susana, Mas, Sergi, Torres, Teresa, Boloc, Daniel, Rodríguez, Natalia, Lafuente, Amalia, Gassó, Patricia, Arnaiz, Joan Albert, Parellada, Eduard

Source: In Journal of Psychiatric Research July 2020 126:8-18