Genomic insights into the 2022–2023Vibrio cholerae outbreak in Malawi

Authors: Chrispin Chaguza, Innocent Chibwe, David Chaima, Patrick Musicha, Latif Ndeketa, Watipaso Kasambara, Chimwemwe Mhango, Upendo L. Mseka, Joseph Bitilinyu-Bangoh, Bernard Mvula, Wakisa Kipandula, Patrick Bonongwe, Richard J. Munthali, Selemani Ngwira, Chikondi A. Mwendera, Akuzike Kalizang’oma, Kondwani C. Jambo, Dzinkambani Kambalame, Arox W. Kamng’ona, A. Duncan Steele, Annie Chauma-Mwale, Daniel Hungerford, Matthew Kagoli, Martin M. Nyaga, Queen Dube, Neil French, Chisomo L. Msefula, Nigel A. Cunliffe, Khuzwayo C. Jere

Source: Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/6b7cbc3890c14711a1a922c4cd6b9c0a

A metagenomic investigation of the faecal RNA virome structure of asymptomatic chickens obtained from a commercial farm in Durban, KwaZulu-Natal province, South Africa

Authors: Vivian C. Nwokorogu, Santhosh Pillai, James E. San, Charlene Pillay, Martin M. Nyaga, Saheed Sabiu

Source: BMC Genomics, Vol 25, Iss 1, Pp 1-20 (2024)

Subject Terms: Viral metagenomics, Faecal virome, RNA viruses, Next-generation sequencing, Poultry, Chicken, Biotechnology, TP248.13-248.65, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2164

Access URL: https://doaj.org/article/3814f14ef5cf40caae32c4e36690b9a0

High Detection Frequency of Vaccine-Associated Polioviruses and Non-Polio Enteroviruses in the Stools of Asymptomatic Infants from the Free State Province, South Africa

Authors: Milton T. Mogotsi, Ayodeji E. Ogunbayo, Hester G. O’Neill, Martin M. Nyaga

Source: Microorganisms, Vol 12, Iss 5, p 920 (2024)

Subject Terms: enteroviruses, NPEV, poliovirus, echoviruses, coxsackievirus, infants, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2076-2607/12/5/920; https://doaj.org/toc/2076-2607

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Genomic Analysis of Rwandan G9P[8] Rotavirus Strains Pre- and Post-RotaTeq® Vaccine Reveals Significant Distinct Sub-Clustering in a Post-Vaccination Cohort

Authors: Robyn-Lee Potgieter, Peter N. Mwangi, Milton T. Mogotsi, Jeannine Uwimana, Leon Mutesa, Narcisse Muganga, Didier Murenzi, Lisine Tusiyenge, Mapaseka L. Seheri, A. Duncan Steele, Jason M. Mwenda, Martin M. Nyaga

Source: Viruses, Vol 15, Iss 12, p 2321 (2023)

Subject Terms: rotavirus, Rwanda, G9P[8], vaccination, whole-genomic analysis, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/15/12/2321; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/dd966503499b4d3bb2da10be3bd8b22e

Poultry gut health – microbiome functions, environmental impacts, microbiome engineering and advancements in characterization technologies

Authors: Christiana Eleojo Aruwa, Charlene Pillay, Martin M. Nyaga, Saheed Sabiu

Source: Journal of Animal Science and Biotechnology, Vol 12, Iss 1, Pp 1-15 (2021)

Subject Terms: Disease, Environmental impacts, Gut microbiome, Microbiome engineering, Poultry health, Animal culture, SF1-1100, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://doaj.org/toc/2049-1891

Access URL: https://doaj.org/article/c86e843f296046fb95f2e8da9892e73a

Genetic characterization of G12P[6] and G12P[8] rotavirus strains collected in six African countries between 2010 and 2014

Authors: Kebareng G. Rakau, Martin M. Nyaga, Maemu P. Gededzha, Jason M. Mwenda, M. Jeffrey Mphahlele, L. Mapaseka Seheri, A. Duncan Steele

Source: BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-15 (2021)

Subject Terms: Rotavirus strains, Africa, G12, P[8], P[6], Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/daa3eb624ee94be2afd83e9e7b0bcf2f

The Evolution of Post-Vaccine G8P[4] Group a Rotavirus Strains in Rwanda; Notable Variance at the Neutralization Epitope Sites

Authors: Peter N. Mwangi, Robyn-Lee Potgieter, Jeannine Uwimana, Leon Mutesa, Narcisse Muganga, Didier Murenzi, Lisine Tusiyenge, Jason M. Mwenda, Milton T. Mogotsi, Kebareng Rakau, Mathew D. Esona, A. Duncan Steele, Mapaseka L. Seheri, Martin M. Nyaga

Source: Pathogens, Vol 12, Iss 5, p 658 (2023)

Subject Terms: G8P[4], rotavirus, Rwanda, whole-genome sequencing, rotavirus reassortment, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-0817/12/5/658; https://doaj.org/toc/2076-0817

Access URL: https://doaj.org/article/092bb1ddf66948888b519336b715ae59

Genomic Analysis of G2P[4] Group A Rotaviruses in Zambia Reveals Positive Selection in Amino Acid Site 7 of Viral Protein 3

Authors: Peter N. Mwangi, Robyn-Lee Potgieter, Julia Simwaka, Evans M. Mpabalwani, Jason M. Mwenda, Milton T. Mogotsi, Nonkululeko Magagula, Mathew D. Esona, A. Duncan Steele, Mapaseka L. Seheri, Martin M. Nyaga

Source: Viruses, Vol 15, Iss 2, p 501 (2023)

Subject Terms: G2P[4], rotavirus, Zambia, whole-genome sequencing, DS-1-like genotype constellation, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/15/2/501; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/96579e4189d947bbb725374959353339

Metagenomic Analysis of Respiratory RNA Virome of Children with and without Severe Acute Respiratory Infection from the Free State, South Africa during COVID-19 Pandemic Reveals Higher Diversity and Abundance in Summer Compared with Winter Period

Authors: Ayodeji E. Ogunbayo, Milton T. Mogotsi, Hlengiwe Sondlane, Kelebogile R. Nkwadipo, Saheed Sabiu, Martin M. Nyaga

Source: Viruses, Vol 14, Iss 11, p 2516 (2022)

Subject Terms: severe acute respiratory infection, virome, metagenomics, children, winter, summer, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/14/11/2516; https://doaj.org/toc/1999-4915

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Plant and Soil Core Mycobiomes in a Two-Year Sorghum–Legume Intercropping System of Underutilized Crops in South Africa

Authors: Gilmore T. Pambuka, Tonjock Rosemary Kinge, Soumya Ghosh, Errol D. Cason, Martin M. Nyaga, Marieka Gryzenhout

Source: Microorganisms, Vol 10, Iss 10, p 2079 (2022)

Subject Terms: core mycobiomes, sorghum, legumes, next-generation sequencing, intercrop, substrates, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2076-2607/10/10/2079; https://doaj.org/toc/2076-2607

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Baseline Data of the Fungal Phytobiome of Three Sorghum (Sorghum bicolor) Cultivars in South Africa using Targeted Environmental Sequencing

Authors: Gilmore T. Pambuka, Tonjock Rosemary Kinge, Soumya Ghosh, Errol D. Cason, Martin M. Nyaga, Marieka Gryzenhout

Source: Journal of Fungi, Vol 7, Iss 11, p 978 (2021)

Subject Terms: sorghum, cultivars, plant tissues, substrates, above ground, below ground, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2309-608X/7/11/978; https://doaj.org/toc/2309-608X

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Genetic Characterisation of South African and Mozambican Bovine Rotaviruses Reveals a Typical Bovine-like Artiodactyl Constellation Derived through Multiple Reassortment Events

Authors: Amy Strydom, Celeste M. Donato, Martin M. Nyaga, Simone S. Boene, Ina Peenze, Milton T. Mogotsi, Eva D. João, Benilde Munlela, A. Christiaan Potgieter, Mapaseka L. Seheri, Nilsa de Deus, Hester G. O’Neill

Source: Pathogens, Vol 10, Iss 10, p 1308 (2021)

Subject Terms: bovine rotavirus, artiodactyl genome constellations, A13 genotype, interspecies transmission, transboundary transmission, South Africa and Mozambique, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-0817/10/10/1308; https://doaj.org/toc/2076-0817

Access URL: https://doaj.org/article/53aca513c189416fbf1f72bdd8654779

Whole Genome Analysis of Human Rotaviruses Reveals Single Gene Reassortant Rotavirus Strains in Zambia

Authors: Wairimu M. Maringa, Julia Simwaka, Peter N. Mwangi, Evans M. Mpabalwani, Jason M. Mwenda, M. Jeffrey Mphahlele, Mapaseka L. Seheri, Martin M. Nyaga

Source: Viruses, Vol 13, Iss 9, p 1872 (2021)

Subject Terms: rotavirus, whole genome, genotype constellation, intergenogroup reassortment, amino acid, Rotarix®, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/13/9/1872; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/6dbb587ada7a42108c115cad190a19a4

The Repurposing of Acetylsalicylic Acid as a Photosensitiser to Inactivate the Growth of Cryptococcal Cells

Authors: Adepemi O. Ogundeji, Nozethu Mjokane, Olufemi S. Folorunso, Carolina H. Pohl, Martin M. Nyaga, Olihile M. Sebolai

Source: Pharmaceuticals, Vol 14, Iss 5, p 404 (2021)

Subject Terms: acetylsalicylic acid (ASA, aspirin), capsule, CAP64, Cryptococcus, membrane potential (ΔΨM), photodynamic treatment, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/14/5/404; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/514c9589f4304f668274e1372fc89aaf

Whole-Genome Analyses Identifies Multiple Reassortant Rotavirus Strains in Rwanda Post-Vaccine Introduction

Authors: Sebotsana Rasebotsa, Jeannine Uwimana, Milton T. Mogotsi, Kebareng Rakau, Nonkululeko B. Magagula, Mapaseka L. Seheri, Jason M. Mwenda, M. Jeffrey Mphahlele, Saheed Sabiu, Richard Mihigo, Leon Mutesa, Martin M. Nyaga

Source: Viruses, Vol 13, Iss 1, p 95 (2021)

Subject Terms: rotavirus, reassortment, whole-genome based surveillance, epitopes, vaccine, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/13/1/95; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/17d37cd11f4740beac6d751673eefa0f

Metagenomic Analysis of the Enteric RNA Virome of Infants from the Oukasie Clinic, North West Province, South Africa, Reveals Diverse Eukaryotic Viruses

Authors: Milton T. Mogotsi, Peter N. Mwangi, Phillip A. Bester, M. Jeffrey Mphahlele, Mapaseka L. Seheri, Hester G. O’Neill, Martin M. Nyaga

Source: Viruses, Vol 12, Iss 11, p 1260 (2020)

Subject Terms: RNA virome, rotavirus, viral metagenomics, enteric viruses, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/12/11/1260; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/6b2a5a50d3f44b0a89db2b6308caa932

Whole Genome In-Silico Analysis of South African G1P[8] Rotavirus Strains before and after Vaccine Introduction over a Period of 14 Years

Authors: Peter N. Mwangi, Milton T. Mogotsi, Mapaseka L. Seheri, M. Jeffrey Mphahlele, Ina Peenze, Mathew D. Esona, Benjamin Kumwenda, A. Duncan Steele, Carl D. Kirkwood, Valantine N. Ndze, Francis E. Dennis, Khuzwayo C. Jere, Martin M. Nyaga

Source: Vaccines, Vol 8, Iss 4, p 609 (2020)

Subject Terms: evolution, rotavirus strains, Wa-like constellation, whole-genome, lineages, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/8/4/609; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/5a95a395347a4c1fbf3e854140027f9a

Molecular Characterisation of a Rare Reassortant Porcine-Like G5P[6] Rotavirus Strain Detected in an Unvaccinated Child in Kasama, Zambia

Authors: Wairimu M. Maringa, Peter N. Mwangi, Julia Simwaka, Evans M. Mpabalwani, Jason M. Mwenda, Ina Peenze, Mathew D. Esona, M. Jeffrey Mphahlele, Mapaseka L. Seheri, Martin M. Nyaga

Source: Pathogens, Vol 9, Iss 8, p 663 (2020)

Subject Terms: whole-genome, genotype constellation, interspecies transmission, reassortment, porcine, porcine-like human, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-0817/9/8/663; https://doaj.org/toc/2076-0817

Access URL: https://doaj.org/article/27d43b4ed5344083aefae9f66d6583e5

Uncovering the First Atypical DS-1-like G1P[8] Rotavirus Strains That Circulated during Pre-Rotavirus Vaccine Introduction Era in South Africa

Authors: Peter N. Mwangi, Milton T. Mogotsi, Sebotsana P. Rasebotsa, Mapaseka L. Seheri, M. Jeffrey Mphahlele, Valantine N. Ndze, Francis E. Dennis, Khuzwayo C. Jere, Martin M. Nyaga

Source: Pathogens, Vol 9, Iss 5, p 391 (2020)

Subject Terms: atypical strains, genome constellation, reassortment, rotavirus, whole-genome characterization, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-0817/9/5/391; https://doaj.org/toc/2076-0817

Access URL: https://doaj.org/article/799bbe5025054e1f9c0dbde426cd1554

Using genomics to improve preparedness and response of future epidemics or pandemics in Africa

Authors: Chrispin Chaguza, Martin M Nyaga, Jason M Mwenda, Mathew D Esona, Khuzwayo C Jere

Source: The Lancet Microbe, Vol 1, Iss 7, Pp e275-e276 (2020)

Subject Terms: Medicine (General), R5-920, Microbiology, QR1-502

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666524720301695; https://doaj.org/toc/2666-5247

Access URL: https://doaj.org/article/a7f4a45054ab4d4589399d009cc80ad9