Immune profiling of SARS-CoV-2 infection during pregnancy reveals NK cell and γδ T cell perturbations

Authors: Jennifer R. Habel, Brendon Y. Chua, Lukasz Kedzierski, Kevin J. Selva, Timon Damelang, Ebene R. Haycroft, Thi H.O. Nguyen, Hui-Fern Koay, Suellen Nicholson, Hayley A. McQuilten, Xiaoxiao Jia, Lilith F. Allen, Luca Hensen, Wuji Zhang, Carolien E. van de Sandt, Jessica A. Neil, Katherine Pragastis, Jillian S.Y. Lau, Jaycee Jumarang, E. Kaitlynn Allen, Fatima Amanant, Florian Krammer, Kathleen M. Wragg, Jennifer A. Juno, Adam K. Wheatley, Hyon-Xhi Tan, Gabrielle Pell, Susan Walker, Jennifer Audsley, Arnold Reynaldi, Irani Thevarajan, Justin T. Denholm, Kanta Subbarao, Miles P. Davenport, P. Mark Hogarth, Dale I. Godfrey, Allen C. Cheng, Steven Y.C. Tong, Katherine Bond, Deborah A. Williamson, James H. McMahon, Paul G. Thomas, Pia S. Pannaraj, Fiona James, Natasha E. Holmes, Olivia C. Smibert, Jason A. Trubiano, Claire L. Gordon, Amy W. Chung, Clare L. Whitehead, Stephen J. Kent, Martha Lappas, Louise C. Rowntree, Katherine Kedzierska

Source: JCI Insight, Vol 8, Iss 7 (2023)

Subject Terms: Immunology, Infectious disease, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/5baf2d86cad54efcaef6a7913823280a

Extracellular vesicle-associated miRNAs are an adaptive response to gestational diabetes mellitus

Authors: Soumyalekshmi Nair, Dominic Guanzon, Nanthini Jayabalan, Andrew Lai, Katherin Scholz-Romero, Priyakshi Kalita de Croft, Valeska Ormazabal, Carlos Palma, Emilio Diaz, Elizabeth A. McCarthy, Alexis Shub, Jezid Miranda, Eduard Gratacós, Fátima Crispi, Gregory Duncombe, Martha Lappas, H. David McIntyre, Gregory Rice, Carlos Salomon

Source: Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-17 (2021)

Subject Terms: Pregnancy, Exosomes, miRNAs, Insulin resistance, Skeletal muscle, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/459eca6bdc89459c879879f07f4b0b45

Antibody mediated activation of natural killer cells in malaria exposed pregnant women

Authors: Timon Damelang, Elizabeth H. Aitken, Wina Hasang, Ester Lopez, Martin Killian, Holger W. Unger, Ali Salanti, Alexis Shub, Elizabeth McCarthy, Katherine Kedzierska, Martha Lappas, Stephen J. Kent, Stephen J. Rogerson, Amy W. Chung

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/27cc8554f9a544d6a5a259ece4468ade

The effect of breastfeeding on postpartum glucose tolerance and lipid profiles in women with gestational diabetes mellitus

Authors: Alexis Shub, Manisha Miranda, Harry M. Georgiou, Elizabeth A. McCarthy, Martha Lappas

Source: International Breastfeeding Journal, Vol 14, Iss 1, Pp 1-5 (2019)

Subject Terms: Gestational diabetes mellitus, Breastfeeding, Glucose intolerance, Pediatrics, RJ1-570, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13006-019-0238-5; https://doaj.org/toc/1746-4358

Access URL: https://doaj.org/article/bb86d6af02334c049e4b3908e60f199c

Editorial: The Role of the Fetal Membranes in Pregnancy and Birth

Authors: Ramkumar Menon, Martha Lappas, Tamas Zakar

Source: Frontiers in Physiology, Vol 12 (2021)

Subject Terms: fetal membranes, PPROM, preterm birth, amniochorion, pregnancy, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2021.653084/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/fc28dc71e46549d2812c9bb7f51a3ad6

Sleep-disordered breathing does not impact maternal outcomes in women with hypertensive disorders of pregnancy.

Authors: Danielle L Wilson, Mark E Howard, Alison M Fung, Fergal J O'Donoghue, Maree Barnes, Martha Lappas, Susan P Walker

Source: PLoS ONE, Vol 15, Iss 4, p e0232287 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/3c14989d474749bd9b9f934c8edf5ceb

The presence of coexisting sleep-disordered breathing among women with hypertensive disorders of pregnancy does not worsen perinatal outcome.

Authors: Danielle L Wilson, Mark E Howard, Alison M Fung, Fergal J O'Donoghue, Maree Barnes, Martha Lappas, Susan P Walker

Source: PLoS ONE, Vol 15, Iss 2, p e0229568 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/94fbf4e4377544c1a41d538d1a8c035f

Inhibition of GPR91 Reduces Inflammatory Mediators Involved in Active Labor in Myometrium

Authors: Ratana Lim, Martha Lappas

Source: Mediators of Inflammation, Vol 2020 (2020)

Subject Terms: Pathology, RB1-214

File Description: electronic resource

Relation: https://doaj.org/toc/0962-9351; https://doaj.org/toc/1466-1861

Access URL: https://doaj.org/article/e4cdd91a233f436ab7568fefc9e91e96

Human γδ T‐cell receptor repertoire is shaped by influenza viruses, age and tissue compartmentalisation

Authors: Sneha Sant, Misty R Jenkins, Pradyot Dash, Katherine A Watson, Zhongfang Wang, Angela Pizzolla, Marios Koutsakos, Thi HO Nguyen, Martha Lappas, Jane Crowe, Tom Loudovaris, Stuart I Mannering, Glen P Westall, Tom C Kotsimbos, Allen C Cheng, Linda Wakim, Peter C Doherty, Paul G Thomas, Liyen Loh, Katherine Kedzierska

Source: Clinical & Translational Immunology, Vol 8, Iss 9, Pp n/a-n/a (2019)

Subject Terms: human tissues, human γδ T cells, influenza virus infection, paired TCRγδ repertoire, public GV9‐TCRγ clonotype, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2050-0068

Access URL: https://doaj.org/article/7ff1b72faa64454082fb640c16d1ffe8

Postpartum Circulating Cell-Free Insulin DNA Levels Are Higher in Women with Previous Gestational Diabetes Mellitus Who Develop Type 2 Diabetes in Later Life

Authors: Martha Lappas, Harry M. Georgiou, Jane C. Willcox, Michael Permezel, Alexis Shub, Cody-Lee Maynard, Mugdha V. Joglekar, Anandwardhan A. Hardikar

Source: Journal of Diabetes Research, Vol 2019 (2019)

Subject Terms: Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://doaj.org/toc/2314-6745; https://doaj.org/toc/2314-6753

Access URL: https://doaj.org/article/84788d45b3d5402fb2e7eb6f7aae70c6

Placental Ras Regulates Inflammation Associated with Maternal Obesity

Authors: Stella Liong, Gillian Barker, Martha Lappas

Source: Mediators of Inflammation, Vol 2018 (2018)

Subject Terms: Pathology, RB1-214

File Description: electronic resource

Relation: https://doaj.org/toc/0962-9351; https://doaj.org/toc/1466-1861

Access URL: https://doaj.org/article/2d295bac08cb4bbf9f3aa9b5a116f9be

Identification of SMAD3 as a Novel Mediator of Inflammation in Human Myometrium In Vitro

Authors: Martha Lappas

Source: Mediators of Inflammation, Vol 2018 (2018)

Subject Terms: Pathology, RB1-214

File Description: electronic resource

Relation: https://doaj.org/toc/0962-9351; https://doaj.org/toc/1466-1861

Access URL: https://doaj.org/article/94b37621e9e14a989ff5353b4fad3a34

Cross Talk between Adipose Tissue and Placenta in Obese and Gestational Diabetes Mellitus Pregnancies via Exosomes

Authors: Nanthini Jayabalan, Soumyalekshmi Nair, Zarin Nuzhat, Gregory E. Rice, Felipe A. Zuñiga, Luis Sobrevia, Andrea Leiva, Carlos Sanhueza, Jaime Agustín Gutiérrez, Martha Lappas, Dilys Jane Freeman, Carlos Salomon

Source: Frontiers in Endocrinology, Vol 8 (2017)

Subject Terms: adipose tissue, extracellular vesicles, adipose tissue-derived exosomes, obesity, gestational diabetes, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fendo.2017.00239/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/f8983f04b04f47449e758150b2006759

Resveratrol ameliorates the chemical and microbial induction of inflammation and insulin resistance in human placenta, adipose tissue and skeletal muscle.

Authors: Ha T Tran, Stella Liong, Ratana Lim, Gillian Barker, Martha Lappas

Source: PLoS ONE, Vol 12, Iss 3, p e0173373 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5344491?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/514efb84a39145ecaa72f5761cd727c9

Endoplasmic reticulum stress is increased in adipose tissue of women with gestational diabetes.

Authors: Stella Liong, Martha Lappas

Source: PLoS ONE, Vol 10, Iss 4, p e0122633 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4388824?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/c131a3fc098a423f9f3b68cc094f7987

GSK3β is increased in adipose tissue and skeletal muscle from women with gestational diabetes where it regulates the inflammatory response.

Authors: Martha Lappas

Source: PLoS ONE, Vol 9, Iss 12, p e115854 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4277409?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/49593a806af248e19eece357d31d1337

The citrus flavone nobiletin reduces pro-inflammatory and pro-labour mediators in fetal membranes and myometrium: implications for preterm birth.

Authors: Carrington J Morwood, Martha Lappas

Source: PLoS ONE, Vol 9, Iss 9, p e108390 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4169627?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/ac4a824ef3f54d81a9c8c8ae4707f9a1

Effect of silibinin in reducing inflammatory pathways in in vitro and in vivo models of infection-induced preterm birth.

Authors: Ratana Lim, Carrington J Morwood, Gillian Barker, Martha Lappas

Source: PLoS ONE, Vol 9, Iss 3, p e92505 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3960267?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/88e6ff7311254375a9018e1773def43f

Gestational diabetes is characterized by reduced mitochondrial protein expression and altered calcium signaling proteins in skeletal muscle.

Authors: Kristen E Boyle, Hyonson Hwang, Rachel C Janssen, James M DeVente, Linda A Barbour, Teri L Hernandez, Lawrence J Mandarino, Martha Lappas, Jacob E Friedman

Source: PLoS ONE, Vol 9, Iss 9, p e106872 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4162568?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/49ae8f7b72eb45c4b1211df0e28a8450

Effects of maternal obstructive sleep apnoea on fetal growth: a prospective cohort study.

Authors: Alison M Fung, Danielle L Wilson, Martha Lappas, Mark Howard, Maree Barnes, Fergal O'Donoghue, Stephen Tong, Helen Esdale, Gabrielle Fleming, Susan P Walker

Source: PLoS ONE, Vol 8, Iss 7, p e68057 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23894293/pdf/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/2f75f52ff75f41c1b4e9195ff0cb71ea