Regulatory T cells contribute to the immunosuppressive phenotype of neutrophils in a mouse model of chronic lymphocytic leukemia

Authors: Agnieszka Goral, Marta Sledz, Aneta Manda-Handzlik, Adrianna Cieloch, Alicja Wojciechowska, Mieszko Lachota, Agnieszka Mroczek, Urszula Demkow, Radoslaw Zagozdzon, Katarzyna Matusik, Malgorzata Wachowska, Angelika Muchowicz

Source: Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-16 (2023)

Subject Terms: CD62L, Chronic lymphocytic leukemia (CLL), Neutrophils, Regulatory T cells (Treg), Immunosuppression, Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-3619

Access URL: https://doaj.org/article/17a750dffacc4707803a8fb0469caae8

A Specific CD44lo CD25lo Subpopulation of Regulatory T Cells Inhibits Anti-Leukemic Immune Response and Promotes the Progression in a Mouse Model of Chronic Lymphocytic Leukemia

Authors: Agnieszka Goral, Malgorzata Firczuk, Klaudyna Fidyt, Marta Sledz, Francesca Simoncello, Karolina Siudakowska, Giulia Pagano, Etienne Moussay, Jérôme Paggetti, Patrycja Nowakowska, Stefania Gobessi, Joanna Barankiewicz, Aleksander Salomon-Perzynski, Federica Benvenuti, Dimitar G. Efremov, Przemyslaw Juszczynski, Ewa Lech-Maranda, Angelika Muchowicz

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: Tregs, CLL, Eµ-TCL1, MALT1, TCR repertoire, anti-leukemic immune response, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.781364/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/d570ed76fde2440298405ceec85cbbaf