Oncolytic adenoviruses and immunopeptidomics: a convenient marriage

Authors: Marc Garcia‐Moure, Andrew G. Gillard, Marta M. Alonso, Juan Fueyo, Candelaria Gomez‐Manzano

Source: Molecular Oncology, Vol 18, Iss 4, Pp 781-784 (2024)

Subject Terms: adenovirus, cancer, mesothelioma, personalized, vaccine, virotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/f196420c54cc4f3dabd5e868f56a064a

The heterogeneous sensitivity of pediatric brain tumors to different oncolytic viruses is predicted by unique gene expression profiles

Authors: Konstantinos Vazaios, Εftychia Stavrakaki, Lisette B. Vogelezang, Jie Ju, Piotr Waranecki, Dennis S. Metselaar, Michaël H. Meel, Vera Kemp, Bernadette G. van den Hoogen, Rob C. Hoeben, E. Antonio Chiocca, William F. Goins, Andrew Stubbs, Yunlei Li, Marta M. Alonso, Friso G. Calkoen, Esther Hulleman, Jasper van der Lugt, Martine L.M. Lamfers

Source: Molecular Therapy: Oncology, Vol 32, Iss 2, Pp 200804- (2024)

Subject Terms: MT: Regular Issue, pediatric brain tumors, oncolytic viruses, sensitivity, resistance, Gene Ontology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2950329924000468; https://doaj.org/toc/2950-3299

Access URL: https://doaj.org/article/4f89f9ae6af94262a419f5c33cbc8f5b

Characterization of immune populations in the tumor microenvironment of diffuse midline glioma orthotopic mouse models by flow cytometry

Authors: Iker Ausejo-Mauleon, Sara Labiano, Marta M. Alonso

Source: STAR Protocols, Vol 5, Iss 1, Pp 102803- (2024)

Subject Terms: Flow Cytometry, Cancer, Immunology, Science (General), Q1-390

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666166723007700; https://doaj.org/toc/2666-1667

Access URL: https://doaj.org/article/cb504450ac8f410193a03eda74f9847a

The rise of TIM‐3: A promising immune target in diffuse midline gliomas

Authors: Iker Ausejo‐Mauleon, Sara Nuin, Marta M. Alonso

Source: Clinical and Translational Medicine, Vol 14, Iss 1, Pp n/a-n/a (2024)

Subject Terms: Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2001-1326

Access URL: https://doaj.org/article/ec1fa14314fd467691b97c925a3551ae

CD4 T CELL MODULATION IS NEUROPROTECTIVE IN AN AAV9-MEDIATED A-SYNUCLEIN OVEREXPRESSION MOUSE MODEL OF PARKINSON´S DISEASE

Authors: Adriana Tavira, Leyre Basurco, Miguel Angel Abellanas, Leyre Ayerra, Rodrigo Vinueza-Gavilanes, Esther Luquin, Lucia Marrodan, Marta M. Alonso, Pedro Clavero, Elisa Mengual, Monserrat Arrasate, Sandra Hervás-Stubbs, Maria S. Aymerich

Source: IBRO Neuroscience Reports, Vol 15, Iss , Pp S291-S292 (2023)

Subject Terms: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2667242123005778; https://doaj.org/toc/2667-2421

Access URL: https://doaj.org/article/3c4663e1af7b49ac81a0ccf347b4b790

Translational considerations for immunotherapy clinical trials in pediatric neuro-oncology

Authors: Jessica B. Foster, Marta M. Alonso, Elias Sayour, Tom B. Davidson, Mika L. Persson, Matthew D. Dun, Cassie Kline, Sabine Mueller, Nicholas A. Vitanza, Jasper van der Lugt

Source: Neoplasia: An International Journal for Oncology Research, Vol 42, Iss , Pp 100909- (2023)

Subject Terms: Immunotherapy, Pediatric cancer, Brain tumor, Central nervous system tumor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558623000349; https://doaj.org/toc/1476-5586

Access URL: https://doaj.org/article/83a724b0107446558a0c82a6d7c6ddff

Galectin-3 inhibition boosts the therapeutic efficacy of Semliki Forest virus in pediatric osteosarcoma

Authors: Guillermo Herrador-Cañete, Marta Zalacain, Sara Labiano, Virginia Laspidea, Montserrat Puigdelloses, Lucía Marrodan, Marc Garcia-Moure, Marisol Gonzalez-Huarriz, Javier Marco-Sanz, Iker Ausejo-Mauleon, Daniel de la Nava, Reyes Hernández-Osuna, Javier Martínez-García, Noelia Silva-Pilipich, Elisabeth Gurucega, Ana Patiño-García, Rubén Hernández-Alcoceba, Cristian Smerdou, Marta M. Alonso

Source: Molecular Therapy: Oncolytics, Vol 26, Iss , Pp 246-264 (2022)

Subject Terms: Galectin-3, Semliki Forest virus, virotherapy, immunotherapy, osteosarcoma, pediatric cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2372770522000936; https://doaj.org/toc/2372-7705

Access URL: https://doaj.org/article/aa6be58f880644d78c5e92d41cf868e1

Local administration of IL-12 with an HC vector results in local and metastatic tumor control in pediatric osteosarcoma

Authors: Marta Zalacain, María Bunuales, Lucía Marrodan, Sara Labiano, Marisol Gonzalez-Huarriz, Naiara Martinez-Vélez, Virginia Laspidea, Montse Puigdelloses, Marc García-Moure, Manuela Gonzalez-Aparicio, Rubén Hernandez-Alcoceba, Marta M. Alonso, Ana Patiño-García

Source: Molecular Therapy: Oncolytics, Vol 20, Iss , Pp 23-33 (2021)

Subject Terms: Pediatric solid tumors, therapy, osteosarcoma, high capacity adenoviral vectors, immunotherapy, IL-12, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2372770520301686; https://doaj.org/toc/2372-7705

Access URL: https://doaj.org/article/31c2c8191c8240cdb76ac36ee4d1b26d

Immunovirotherapy for Pediatric Solid Tumors: A Promising Treatment That is Becoming a Reality

Authors: Daniel de la Nava, Kadir Mert Selvi, Marta M. Alonso

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: oncolytic viruses, pediatric solid tumors, pediatric brain tumors, sarcomas, neuroblastoma, clinical trials, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.866892/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/1df05242ffe843a18f8125a9111eb128

Exploiting 4-1BB immune checkpoint to enhance the efficacy of oncolytic virotherapy for diffuse intrinsic pontine gliomas

Authors: Virginia Laspidea, Montserrat Puigdelloses, Sara Labiano, Lucía Marrodán, Marc Garcia-Moure, Marta Zalacain, Marisol Gonzalez-Huarriz, Naiara Martínez-Vélez, Iker Ausejo-Mauleon, Daniel de la Nava, Guillermo Herrador-Cañete, Javier Marco-Sanz, Elisabeth Guruceaga, Carlos E. de Andrea, María Villalba, Oren Becher, Massimo Squatrito, Verónica Matía, Jaime Gállego Pérez-Larraya, Ana Patiño-García, Sumit Gupta, Candelaria Gomez-Manzano, Juan Fueyo, Marta M. Alonso

Source: JCI Insight, Vol 7, Iss 7 (2022)

Subject Terms: Immunology, Oncology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/ce5f44e54382422bab0de99c10b63d55

DNA-damaging cancer cells to improve virotherapy

Authors: Marc Garcia-Moure, Antonio Carlos Tallon-Cobos, Marta M. Alonso

Source: Molecular Therapy: Oncolytics, Vol 27, Iss , Pp 124-125 (2022)

Subject Terms: oncolytic adenoviruses, DDR, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2372770522001243; https://doaj.org/toc/2372-7705

Access URL: https://doaj.org/article/a10a04269d564133b3ee7c481ede1b92

The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models

Authors: Naiara Martínez-Vélez, Marc Garcia-Moure, Miguel Marigil, Marisol González-Huarriz, Montse Puigdelloses, Jaime Gallego Pérez-Larraya, Marta Zalacaín, Lucía Marrodán, Maider Varela-Guruceaga, Virginia Laspidea, Jose Javier Aristu, Luis Isaac Ramos, Sonia Tejada-Solís, Ricardo Díez-Valle, Chris Jones, Alan Mackay, Jose A. Martínez-Climent, Maria Jose García-Barchino, Eric Raabe, Michelle Monje, Oren J. Becher, Marie Pierre Junier, Elias A. El-Habr, Herve Chneiweiss, Guillermo Aldave, Hong Jiang, Juan Fueyo, Ana Patiño-García, Candelaria Gomez-Manzano, Marta M. Alonso

Source: Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/e70b68b3d2c14bafb5f5185c1fba26c6

Delta-24-RGD combined with radiotherapy exerts a potent antitumor effect in diffuse intrinsic pontine glioma and pediatric high grade glioma models

Authors: Naiara Martinez-Velez, Miguel Marigil, Marc García-Moure, Marisol Gonzalez-Huarriz, Jose Javier Aristu, Luis-Isaac Ramos-García, Sonia Tejada, Ricardo Díez-Valle, Ana Patiño-García, Oren J. Becher, Candelaria Gomez-Manzano, Juan Fueyo, Marta M. Alonso

Source: Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-12 (2019)

Subject Terms: pHGG, DIPG, Radiotherapy, Oncolytic virus, DNA damage, Immune response, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-019-0714-6; https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/48ebc806f5dd44a9b7c4cdfd3de87468

Immunotherapy with CAR-T cells in paediatric haematology-oncology

Authors: Isabel Mirones, Lucas Moreno, Ana Patiño-García, Garbiñe Lizeaga, José M. Moraleda, María Luisa Toribio, Antonio Pérez-Martínez, Luisa Sisinni, Marina García-Morín, Javier Anguita, Manuel Ramírez, Laura Alonso, Susana Rives, Marta M. Alonso, Pilar Palomo, Jaime Verdú-Amorós, Isabel Martínez, Pilar Guerra-García, José Luis Fuster, Andrés Sánchez-Salinas, Miguel Blanquer, Javier García-Castro, María Luisa Toribio e Hisse M. van Santen, Pablo Menéndez

Source: Anales de Pediatría (English Edition), Vol 93, Iss 1, Pp 59.e1-59.e10 (2020)

Subject Terms: Inmunoterapia, Células CAR-T, Cáncer, Terapias avanzadas, Pediatrics, RJ1-570

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S234128792030082X; https://doaj.org/toc/2341-2879

Access URL: https://doaj.org/article/04aef7bb483e4a4c9a790ec0154f9c37

Inmunoterapia con células CAR-T en hematooncología pediátrica

Authors: Isabel Mirones, Lucas Moreno, Ana Patiño-García, Garbiñe Lizeaga, José M. Moraleda, María Luisa Toribio, Antonio Pérez-Martínez, Luisa Sisinni, Marina García-Morín, Javier Anguita, Manuel Ramírez, Miguel Ángel Díaz, Marta González, Laura Alonso, Susana Rives, Marta M. Alonso, Pilar Palomo, Jaime Verdú-Amorós, Isabel Martínez, Pilar Guerra-García, José Luis Fuster, Andrés Sánchez-Salinas, Miguel Blanquer, Javier García-Castro, Hisse M. van Santen, Pablo Menéndez

Source: Anales de Pediatría, Vol 93, Iss 1, Pp 59.e1-59.e10 (2020)

Subject Terms: Immunotherapy, CAR-T cells, Cancer, Advanced therapies, Pediatrics, RJ1-570

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1695403320300163; https://doaj.org/toc/1695-4033

Access URL: https://doaj.org/article/16b70437e8b54743b3869661ec601c68

GPR56/ADGRG1 Inhibits Mesenchymal Differentiation and Radioresistance in Glioblastoma

Authors: Marta Moreno, Leire Pedrosa, Laia Paré, Estela Pineda, Leire Bejarano, Josefina Martínez, Veerakumar Balasubramaniyan, Ravesanker Ezhilarasan, Naveen Kallarackal, Sung-Hak Kim, Jia Wang, Alessandra Audia, Siobhan Conroy, Mercedes Marin, Teresa Ribalta, Teresa Pujol, Antoni Herreros, Avelina Tortosa, Helena Mira, Marta M. Alonso, Candelaria Gómez-Manzano, Francesc Graus, Erik P. Sulman, Xianhua Piao, Ichiro Nakano, Aleix Prat, Krishna P. Bhat, Núria de la Iglesia

Source: Cell Reports, Vol 21, Iss 8, Pp 2183-2197 (2017)

Subject Terms: GPR56, glioblastoma, mesenchymal differentiation, radioresistance, NF-κB, glioma stem-like initiating cell, tumor plasticity, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124717315462; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/a26249bc3090411b9bb7ed6f862f62c4

Oncolytic adenoviruses as a therapeutic approach for osteosarcoma: A new hope

Authors: Marc Garcia-Moure, Naiara Martinez-Vélez, Ana Patiño-García, Marta M. Alonso

Source: Journal of Bone Oncology, Vol 9, Iss , Pp 41-47 (2017)

Subject Terms: Diseases of the musculoskeletal system, RC925-935, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212137416300732; https://doaj.org/toc/2212-1374

Access URL: https://doaj.org/article/c699293a7f854f93b62be31c128c5f39

In silico analysis identifies a putative cell-of-origin for BRAF fusion-positive cerebellar pilocytic astrocytoma

Authors: Subhi Talal Younes, Betty Herrington, Marta M. Alonso

Source: PLoS ONE, Vol 15, Iss 11 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673500/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/4adece39466e4f00a968586ddbe58476

DNX-2401, an Oncolytic Virus, for the Treatment of Newly Diagnosed Diffuse Intrinsic Pontine Gliomas: A Case Report

Authors: Sonia Tejada, Ricardo Díez-Valle, Pablo D. Domínguez, Ana Patiño-García, Marisol González-Huarriz, Juan Fueyo, Cande Gomez-Manzano, Miguel Angel Idoate, Joanna Peterkin, Marta M. Alonso

Source: Frontiers in Oncology, Vol 8 (2018)

Subject Terms: diffuse intrinsic pontine gliomas, phase I clinical trial, oncolytic virus, delta-24-RGD, DNX-2401, intratumoral, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fonc.2018.00061/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/698b4d6ebd734ba0b3a751c84bbdafde

Downmodulation of El A Protein Expression as a Novel Strategy to Design Cancer-Selective Adenoviruses

Authors: Hong Jiang, Ramon Alemany, Candelaria Gomez-Manzano, Diana R. Medrano, Michael G. Lemoine, Melissa V. Olson, Marta M. Alonso, Ok-Hee Lee, Charles C. Conrad, W.K. Alfred Yung, Juan Fueyo

Source: Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 8, Pp 723-729 (2005)

Subject Terms: glioma, oncolytic, adenovirus, E1A, CR1, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558605801046; https://doaj.org/toc/1476-5586; https://doaj.org/toc/1522-8002

Access URL: https://doaj.org/article/491e1777705e404cb344c8429991fbba