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Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair

Authors: Wienert, Beeke, Nguyen, David N., Guenther, Alexis, Feng, Sharon J., Locke, Melissa N., Wyman, Stacia K., Shin, Jiyung, Kazane, Katelynn R., Gregory, Georgia L., Carter, Matthew A. M., Wright, Francis, Conklin, Bruce R., Marson, Alex, Richardson, Chris D., Corn, Jacob E.

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174614703.0x000001&indx=1&recIds=ETOCvdc_100174614703.0x000001

IMMU-38. CRISPR BASED GENOME EDITING OF HUMAN T CELLS TO TARGET H3.3K27M MUTATION IN GLIOMAS

Authors: Hegde, Bindu, Roth, Theodore, Nguyen, David, Chheda, Zinal, Apathy, Ryan, Marson, Alex, Okada, Hideho

Source: Neuro-oncology. 21(Supplement 6):vi127-vi127

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100096831669.0x000001&indx=1&recIds=ETOCvdc_100096831669.0x000001

Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients

Authors: Le Coz, Carole, Nguyen, David N., Su, Chun, Nolan, Brian E., Albrecht, Amanda V., Xhani, Suela, Sun, Di, Demaree, Benjamin, Pillarisetti, Piyush, Khanna, Caroline, Wright, Francis, Chen, Peixin Amy, Yoon, Samuel, Stiegler, Amy L., Maurer, Kelly, Garifallou, James P., Rymaszewski, Amy, Kroft, Steven H., Olson, Timothy S., Seif, Alix E., Wertheim, Gerald, Grant, Struan F.A., Vo, Linda T., Puck, Jennifer M., Sullivan, Kathleen E., Routes, John M., Zakharova, Viktoria, Shcherbina, Anna, Mukhina, Anna, Rudy, Natasha L., Hurst, Anna C.E., Atkinson, T. Prescott, Boggon, Titus J., Hakonarson, Hakon, Abate, Adam R., Hajjar, Joud, Nicholas, Sarah K., Lupski, James R., Verbsky, James, Chinn, Ivan K., Gonzalez, Michael V., Wells, Andrew D., Marson, Alex, Poon, Gregory M.K., Romberg, Neil

Source: The Journal of Experimental Medicine; July 2021, Vol. 218 Issue: 7 pe20201750-e20201750, 1p