Genome-wide DNA methylation analysis in female veterans with military sexual trauma and comorbid PTSD/MDD

Authors: Marra, Pedro S., Seki, Tomoteru, Nishizawa, Yoshitaka, Chang, Gloria, Yamanishi, Kyosuke, Nishiguchi, Tsuyoshi, Shibata, Kazuki, Braun, Patricia, Shinozaki, Gen

Source: In Journal of Affective Disorders 15 April 2024 351:624-630

The genome‐wide DNA methylation profiles among neurosurgery patients with and without post‐operative delirium

Authors: Yamanashi, Takehiko, Crutchley, Kaitlyn J., Wahba, Nadia E., Nagao, Takaaki, Marra, Pedro S., Akers, Cade C., Sullivan, Eleanor J., Iwata, Masaaki, Howard, Mathew A, Cho, Hyunkeun R., Kawasaki, Hiroto, Hughes, Christopher G., Pandharipande, Pratik P., Hefti, Marco M., Shinozaki, Gen

Source: Psychiatry and clinical neurosciences. 77(1):48-55

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100177930578.0x000001&indx=1&recIds=ETOCvdc_100177930578.0x000001

Anti-inflammatory medication use associated with reduced delirium risk and all-cause mortality: A retrospective cohort study

Authors: Yamanashi, Takehiko, Sullivan, Eleanor J., Comp, Katie R., Nishizawa, Yoshitaka, Akers, Cade C., Chang, Gloria, Modukuri, Manisha, Tran, Tammy, Anderson, Zoe-Ella E.M., Marra, Pedro S., Crutchley, Kaitlyn J., Wahba, Nadia E., Iwata, Masaaki, Karam, Matthew D., Noiseux, Nicolas O., Cho, Hyunkeun R., Shinozaki, Gen

Source: In Journal of Psychosomatic Research May 2023 168

Genome-wide DNA methylation analysis of post-operative delirium with brain, blood, saliva, and buccal samples from neurosurgery patients

Authors: Wahba, Nadia E., Nishizawa, Yoshitaka, Marra, Pedro S., Yamanashi, Takehiko, Crutchley, Kaitlyn J., Nagao, Takaaki, Shibata, Kazuki, Nishiguchi, Tsuyoshi, Cho, Hyunkeun, Howard, Mathew A., III, Kawasaki, Hiroto, Hefti, Marco, Kanazawa, Tetsufumi, Shinozaki, Gen

Source: In Journal of Psychiatric Research December 2022 156:245-251

DNA methylation in the TNF-alpha gene decreases along with aging among delirium inpatients

Authors: Yamanashi, Takehiko, Saito, Taku, Yu, Tong, Alario, Alexandra, Comp, Katie, Crutchley, Kaitlyn J., Sullivan, Eleanor J., Anderson, Zoe-Ella M., Marra, Pedro S., Chang, Gloria, Wahba, Nadia E., Jellison, Sydney S., Meyer, Alissa A., Mathur, Srishti, Pandharipande, Pratik, Yoshino, Aihide, Kaneko, Koichi, Lee, Sangil, Toda, Hiroyuki, Iwata, Masaaki, Shinozaki, Gen

Source: In Neurobiology of Aging September 2021 105:310-317

New Cutoff Scores for Delirium Screening Tools to Predict Patient Mortality

Authors: Yamanashi, Takehiko, Iwata, Masaaki, Crutchley, Kaitlyn J., Sullivan, Eleanor J., Malicoat, Johnny R., Anderson, Zoe‐Ella M., Marra, Pedro S., Chang, Gloria, Kaneko, Koichi, Shinozaki, Eri, Lee, Sangil, Shinozaki, Gen

Source: Journal of the American Geriatrics Society. 69(1):140-147

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122919068.0x000001&indx=1&recIds=ETOCvdc_100122919068.0x000001

The Bispectral Electroencephalography Method Quantifies Postoperative Delirium-Like States in Young and Aged Male Mice After Head-Mount Implantation Surgery.

Authors: Nishiguchi, Tsuyoshi, Shibata, Kazuki, Yamanishi, Kyosuke, Dittrich, Mia Nicole, Islam, Noah Yuki, Patel, Shivani, Phuong, Nathan James, Marra, Pedro S, Malicoat, Johnny R, Seki, Tomoteru, Nishizawa, Yoshitaka, Yamanashi, Takehiko, Iwata, Masaaki, Shinozaki, Gen

Source: Journals of Gerontology Series A: Biological Sciences & Medical Sciences; Aug2024, Vol. 79 Issue 8, p1-5, 5p

Subject Terms: ANIMAL experimentation, OLDER people, ANIMAL models in research, DELIRIUM, QUANTITATIVE research

Epigenetic signals associated with delirium replicated across four independent cohorts.

Authors: Nishizawa, Yoshitaka, Thompson, Kaitlyn C., Yamanashi, Takehiko, Wahba, Nadia E., Saito, Taku, Marra, Pedro S., Nagao, Takaaki, Nishiguchi, Tsuyoshi, Shibata, Kazuki, Yamanishi, Kyosuke, Hughes, Christopher G., Pandharipande, Pratik, Cho, Hyunkeun, Howard III, Matthew A., Kawasaki, Hiroto, Toda, Hiroyuki, Kanazawa, Tetsufumi, Iwata, Masaaki, Shinozaki, Gen

Source: Translational Psychiatry; 7/4/2024, Vol. 14 Issue 1, p1-7, 7p

Mortality among patients with sepsis associated with a bispectral electroencephalography (BSEEG) score.

Authors: Yamanashi, Takehiko^1,2,3, Marra, Pedro S.², Crutchley, Kaitlyn J.², Wahba, Nadia E.², Malicoat, Johnny R.², Sullivan, Eleanor J.², Akers, Cade C.², Nicholson, Catherine A.², Herrmann, Felipe M.², Karam, Matthew D.⁴, Noiseux, Nicolas O.⁴, Kaneko, Koichi³, Shinozaki, Eri⁵, Iwata, Masaaki³, Cho, Hyunkeun Ryan⁶, Lee, Sangil⁷, Shinozaki, Gen^1,2 gens@stanford.edu

Source: Scientific Reports. 7/9/2021, Vol. 11 Issue 1, p1-8. 8p.

Subject Terms: *SEPSIS, *ELECTROENCEPHALOGRAPHY, *DIAGNOSIS of delirium, *HEALTH outcome assessment, *DISEASE management, *COMORBIDITY

(PO-025) Mortality Among Patients with Sepsis Associated with a Bispectral Electroencephalography (BSEEG) Score

Authors: Marra, Pedro S., Crutchley, Kaitlyn, Wahba, Nadiah, Sullivan, Eleanor, Comp, Katie, Yamanashi, Takehiko, Shinozaki, Gen

Source: Journal of the Academy of Consultation. 63(S):S12-S13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167414160.0x000001&indx=1&recIds=ETOCvdc_100167414160.0x000001

A Bispectral EEG Device and Standard Deviation Filtering Can Capture Delirium Severity and Predict Mortality

Authors: Crutchley, Kaitlyn, Marra, Pedro S., Wahba, Nadiah, Sullivan, Eleanor, Comp, Katie, Yamanashi, Takehiko, Shinozaki, Gen

Source: Journal of the Academy of Consultation. 63(S):S93-S94

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167412767.0x000001&indx=1&recIds=ETOCvdc_100167412767.0x000001

NSAIDs use history: impact on the genome-wide DNA methylation profile and possible mechanisms of action.

Authors: Marra, Pedro S.^1,2 (AUTHOR), Nishizawa, Yoshitaka^1,3 (AUTHOR), Yamanashi, Takehiko^1,4 (AUTHOR), Sullivan, Eleanor J.² (AUTHOR), Comp, Katie R.² (AUTHOR), Crutchley, Kaitlyn J.⁵ (AUTHOR), Wahba, Nadia E.⁶ (AUTHOR), Shibata, Kazuki^1,7 (AUTHOR), Nishiguchi, Tsuyoshi^1,4 (AUTHOR), Yamanishi, Kyosuke^1,8 (AUTHOR), Noiseux, Nicolas O.⁹ (AUTHOR), Karam, Matthew D.⁹ (AUTHOR), Shinozaki, Gen^1,2 (AUTHOR) gens@stanford.edu

Source: Clinical & Experimental Medicine. Nov2023, Vol. 23 Issue 7, p3509-3516. 8p.

Subject Terms: *DNA methylation, *NONSTEROIDAL anti-inflammatory agents, *ELECTRONIC health records, *LINOLEIC acid, *ARACHIDONIC acid, *IMMUNOSENESCENCE, *EPIGENOMICS

Metformin Reduced Delirium Risk and All-Cause Mortality: Retrospective Observational Study

Authors: Shinozaki, Gen, Marra, Pedro S., Crutchley, Kaitlyn J., Wahba, Nadiah, Yamanashi, Takehiko

Source: Journal of the Academy of Consultation. 63(S2):S232-S232

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195050232.0x000001&indx=1&recIds=ETOCvdc_100195050232.0x000001

How a Swollen Finger Made Me Forget About the Scalpel: How a Swollen Finger Made Me Forget About the Scalpel.

Authors: Marra, Pedro S.¹ (AUTHOR) pedro.marra@ucsf.edu

Source: JGIM: Journal of General Internal Medicine. Dec2024, Vol. 39 Issue 16, p3355-3355. 1p.

Subject Terms: *MEDICAL students, *HOLMES, Sherlock (Fictional character), *MEDICAL specialties & specialists, *SUTURING, *PLASTIC surgery

Evaluation of point-of-care thumb-size bispectral electroencephalography device to quantify delirium severity and predict mortality.

Authors: Yamanashi, Takehiko, Crutchley, Kaitlyn J., Wahba, Nadia E., Sullivan, Eleanor J., Comp, Katie R., Kajitani, Mari, Tran, Tammy, Modukuri, Manisha V., Marra, Pedro S., Herrmann, Felipe M., Chang, Gloria, Anderson, Zoe-Ella M., Iwata, Masaaki, Kobayashi, Ken, Kaneko, Koichi, Umeda, Yuhei, Kadooka, Yoshimasa, Lee, Sangil, Shinozaki, Eri, Karam, Matthew D.

Source: British Journal of Psychiatry; Jun2022, Vol. 220 Issue 6, p322-329, 8p

DNA methylation in the inflammatory genes after neurosurgery and diagnostic ability of post-operative delirium.

Authors: Yamanashi, Takehiko, Nagao, Takaaki, Wahba, Nadia E., Marra, Pedro S., Crutchley, Kaitlyn J., Meyer, Alissa A., Andreasen, Ally J., Hellman, Mandy M., Jellison, Sydney S., Hughes, Christopher G., Pandharipande, Pratik P., Howard, III, Matthew A., Kawasaki, Hiroto, Iwata, Masaaki, Hefti, Marco M., Shinozaki, Gen

Source: Translational Psychiatry; 12/9/2021, Vol. 11, p1-10, 10p

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