B cell–intrinsic TLR7 expression drives severe lupus in TLR9-deficient mice

Authors: Haylee A. Cosgrove, Sebastien Gingras, Minjung Kim, Sheldon Bastacky, Jeremy S. Tilstra, Mark J. Shlomchik

Source: JCI Insight, Vol 8, Iss 16 (2023)

Subject Terms: Autoimmunity, Immunology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/4b6317968eb343848419b89127f8584f

The citrullinated/native index of autoantibodies against hnRNP-DL predicts an individual 'window of treatment success' in RA patients

Authors: Bianka Marklein, Madeleine Jenning, Zoltán Konthur, Thomas Häupl, Franziska Welzel, Ute Nonhoff, Sylvia Krobitsch, Debbie M. Mulder, Marije I. Koenders, Vijay Joshua, Andrew P. Cope, Mark J. Shlomchik, Hans-Joachim Anders, Gerd R. Burmester, Aase Hensvold, Anca I. Catrina, Johan Rönnelid, Günter Steiner, Karl Skriner

Source: Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-16 (2021)

Subject Terms: Rheumatoid arthritis, ACPA, Anti-CCP, Rheumatoid factor, Shared epitope, Systemic lupus erythematosus, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/6e28ab54dbcf4c858aedc3ba90e27fcf

Rubicon promotes rather than restricts murine lupus and is not required for LC3-associated phagocytosis

Authors: Rachael A. Gordon, Christina Giannouli, Chirag Raparia, Sheldon I. Bastacky, Anthony Marinov, William Hawse, Richard Cattley, Jeremy S. Tilstra, Allison M. Campbell, Kevin M. Nickerson, Anne Davidson, Mark J. Shlomchik

Source: JCI Insight, Vol 7, Iss 7 (2022)

Subject Terms: Autoimmunity, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/3c1ff191a0484eb9a817b3dcb6dde47f

Heterogeneity and clonality of kidney-infiltrating T cells in murine lupus nephritis

Authors: Shuchi Smita, Maria Chikina, Mark J. Shlomchik, Jeremy S. Tilstra

Source: JCI Insight, Vol 7, Iss 8 (2022)

Subject Terms: Autoimmunity, Immunology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/ef93804a4bec45d1985cd36146dcc059

Correction to: The citrullinated/native index of autoantibodies against hnRNP-DL predicts an individual 'window of treatment success' in RA patients

Authors: Bianka Marklein, Madeleine Jenning, Zoltán Konthur, Thomas Häupl, Franziska Welzel, Ute Nonhoff, Sylvia Krobitsch, Debbie M. Mulder, Marije I. Koenders, Vijay Joshua, Andrew P. Cope, Mark J. Shlomchik, Hans-Joachim Anders, Gerd R. Burmester, Aase Hensvold, Anca I. Catrina, Johan Rönnelid, Günter Steiner, Karl Skriner

Source: Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-2 (2021)

Subject Terms: Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/c6a3f6ea4dc34591a50ebdb7f3693e1d

IL-12 Blocks Tfh Cell Differentiation during Salmonella Infection, thereby Contributing to Germinal Center Suppression

Authors: Rebecca A. Elsner, Mark J. Shlomchik

Source: Cell Reports, Vol 29, Iss 9, Pp 2796-2809.e5 (2019)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S221112471931383X; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/81dd2af310774450b462c3fc98fa5b97

Context-Specific BAFF-R Signaling by the NF-κB and PI3K Pathways

Authors: Julia Jellusova, Ana V. Miletic, Matthew H. Cato, Wai-Wai Lin, Yinling Hu, Gail A. Bishop, Mark J. Shlomchik, Robert C. Rickert

Source: Cell Reports, Vol 5, Iss 4, Pp 1022-1035 (2013)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124713006062; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/5d1ed188fbb94d17b1bf41509e7f8612

Murine lupus is neutrophil elastase-independent in the MRL.Faslpr model.

Authors: Rachael A Gordon, Jeremy S Tilstra, Anthony Marinov, Kevin M Nickerson, Sheldon I Bastacky, Mark J Shlomchik

Source: PLoS ONE, Vol 15, Iss 4, p e0226396 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0226396&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/85e463fd0b2544e280c52de750b2e124

BRAF V600E and Pten deletion in mice produces a histiocytic disorder with features of Langerhans cell histiocytosis.

Authors: David S Nelson, Ryan L Marano, Yechaan Joo, Sara Y Tian, Bhumi Patel, Daniel H Kaplan, Mark J Shlomchik, Kristen Stevenson, Roderick T Bronson, Barrett J Rollins

Source: PLoS ONE, Vol 14, Iss 9, p e0222400 (2019)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/558463d275d0429ebb07e2d707219cea

Toll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice.

Authors: Kevin M Nickerson, Yujuan Wang, Sheldon Bastacky, Mark J Shlomchik

Source: PLoS ONE, Vol 12, Iss 3, p e0173471 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5344451?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/0b865c572e30400189c2ed5a59120094

CD73 expression is dynamically regulated in the germinal center and bone marrow plasma cells are diminished in its absence.

Authors: Laura J Conter, Eunice Song, Mark J Shlomchik, Mary M Tomayko

Source: PLoS ONE, Vol 9, Iss 3, p e92009 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3963874?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/cb8bb286e44442008442e0b00589cc32

Autoimmunity: The genes and phenotypes of autoimmunity

Authors: Mark J, Shlomchik¹ mark.shlomchik@yale.edu, Martin, Weigert² mweigert@bsd.uchicago.edu

Source: Current Opinion in Immunology. Dec2004, Vol. 16 Issue 6, p738-740. 3p.

804 Genetic dissection of TLR9 reveals complex regulatory and cryptic pro-inflammatory roles in murine lupus

Authors: Mark J Shlomchik, Claire Leibler, Shinu John, Shuchi Smita, Rachael Gordon, Sebastien Gingras, Sheldon Bastacky, Kensuke Miyake, Rebecca A Elsner, Kayla B Thomas, Stephen Joachim, Russell C Levack, Derrick Callahan, Ryutaro Fukui, Kevin M Nickerson

Source: Lupus Science and Medicine, Vol 11, Iss Suppl 2 (2024)

Subject Terms: Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2053-8790

Access URL: https://doaj.org/article/7e866731d48b4a219781ba0c08e5ac84

Improved methods for detecting selection by mutation analysis of Ig V region sequences.

Authors: Uri Hershberg, Mohamed Uduman, Mark J. Shlomchik, Steven H. Kleinstein

Source: International Immunology; May2008, Vol. 20 Issue 5, p683-683, 1p

Subject Terms: GENETIC mutation, B cells, LYMPHOCYTES, LABORATORY mice

207 ABC and extrafollicular responses: mechanistic insights from murine models of lupus and infection

Authors: Mark J Shlomchik, Kevin Nickerson, Rebecca Elsner, Nikita Trivedi

Source: Lupus Science and Medicine, Vol 9, Iss Suppl 3 (2022)

Subject Terms: Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2053-8790

Access URL: https://doaj.org/article/16a3635a5e904b7eacfb6a8bc89b58fe

402 Genetic dissection of TLR9 reveals complex regulatory and cryptic pro-inflammatory roles

Authors: Mark J Shlomchik, Jeremy Tilstra, Claire Leibler, Shinu John, Kayla Thomas, Shuchi Smita, Rachael Gordon, Sebastien Gingras, Sheldon Bastacky, Kevin Nickerson

Source: Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)

Subject Terms: Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2053-8790

Access URL: https://doaj.org/article/ef5c1f2c803245258c493e45c352c84a

B cells are capable of independently eliciting rapid reactivation of encephalitogenic CD4 T cells in a murine model of multiple sclerosis.

Authors: Chelsea R Parker Harp, Angela S Archambault, Julia Sim, Mark J Shlomchik, John H Russell, Gregory F Wu

Source: PLoS ONE, Vol 13, Iss 6, p e0199694 (2018)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0199694&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/485ded0f63a5431fb7b38915fa92e06c