The synthetic opioid fentanyl increases HIV replication in macrophages.

Authors: Janani Madhuravasal Krishnan, Ling Kong, Heidi L Meeds, Krishna M Roskin, Mario Medvedovic, Kenneth E Sherman, Jason T Blackard

Source: PLoS ONE, Vol 20, Iss 2, p e0298341 (2025)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/49c04f982dcf4761bc875583e7dd9890

MAP3K1 regulates female reproductive tract development

Authors: Eiki Kimura, Maureen Mongan, Bo Xiao, Antonius Christianto, Jingjing Wang, Vinicius S. Carreira, Brad Bolon, Xiang Zhang, Katherine A. Burns, Jacek Biesiada, Mario Medvedovic, Alvaro Puga, Ying Xia

Source: Disease Models & Mechanisms, Vol 17, Iss 3 (2024)

Subject Terms: female reproductive tract, imperforate vagina, map3k1, müllerian duct, wnt signaling, Medicine, Pathology, RB1-214

File Description: electronic resource

Relation: http://dmm.biologists.org/content/17/3/dmm050669; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411

Access URL: https://doaj.org/article/dd7b0bd517df4bf9b9bf58ec980d661c

Axl regulated survival/proliferation network and its therapeutic intervention in mouse models of glomerulonephritis

Authors: Yuxuan Zhen, Yan Ren, Mario Medvedovic, David E. Adams, Diping Wang, Wen-Hai Shao

Source: Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-12 (2022)

Subject Terms: Anti-GBM nephritis, Axl receptor tyrosine kinase, Lupus nephritis, R428, T cell infiltration, BUN, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/2dab5154ba9c4783a3a9f0daef9c3a33

Connecting omics signatures and revealing biological mechanisms with iLINCS

Authors: Marcin Pilarczyk, Mehdi Fazel-Najafabadi, Michal Kouril, Behrouz Shamsaei, Juozas Vasiliauskas, Wen Niu, Naim Mahi, Lixia Zhang, Nicholas A. Clark, Yan Ren, Shana White, Rashid Karim, Huan Xu, Jacek Biesiada, Mark F. Bennett, Sarah E. Davidson, John F. Reichard, Kurt Roberts, Vasileios Stathias, Amar Koleti, Dusica Vidovic, Daniel J. B. Clarke, Stephan C. Schürer, Avi Ma’ayan, Jarek Meller, Mario Medvedovic

Source: Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/08ffc15267ee4c3faac75343be39e39f

Hexavalent chromium promotes differential binding of CTCF to its cognate sites in Euchromatin

Authors: Andrew VonHandorf, Hesbon A. Zablon, Jacek Biesiada, Xiang Zhang, Mario Medvedovic, Alvaro Puga

Source: Epigenetics, Vol 16, Iss 12, Pp 1361-1376 (2021)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1559-2294; https://doaj.org/toc/1559-2308

Access URL: https://doaj.org/article/9c1fa3ba7b1b499b9515b1722e79db17

Metformin increases natural killer cell functions in head and neck squamous cell carcinoma through CXCL1 inhibition

Authors: Maria A Lehn, Trisha M Wise-Draper, Shuchi Gulati, Vinita Takiar, Sarah Palackdharry, Mario Medvedovic, Timothy Stone, Joseph Curry, Vidhya Karivedu, McKenzie Crist, Benyamin Yaniv, Michael Borchers, Bethany Fuhrman, Audrey Crago, Ubaldo Martinez-Outschoorn

Source: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 11 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/10/11/e005632.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/d5e39b30e67c484baead80341faf7c76

The Synthetic Opioid Fentanyl Increases HIV Replication and Chemokine Co-Receptor Expression in Lymphocyte Cell Lines

Authors: Janani Madhuravasal Krishnan, Ling Kong, Rebekah Karns, Mario Medvedovic, Kenneth E. Sherman, Jason T. Blackard

Source: Viruses, Vol 15, Iss 4, p 1027 (2023)

Subject Terms: opioid, fentanyl, drug use, HIV, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/15/4/1027; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/0e8cadda900849b5a87b9254137f20bf

An Organoid-Based Preclinical Model of Human Gastric CancerSummary

Authors: Nina G. Steele, Jayati Chakrabarti, Jiang Wang, Jacek Biesiada, Loryn Holokai, Julie Chang, Lauren M. Nowacki, Jennifer Hawkins, Maxime Mahe, Nambirajan Sundaram, Noah Shroyer, Mario Medvedovic, Michael Helmrath, Syed Ahmad, Yana Zavros

Source: Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 161-184 (2019)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X18301309; https://doaj.org/toc/2352-345X

Access URL: https://doaj.org/article/0b3344e92de44f69ab10a3fbb7d5b624

Chromium disrupts chromatin organization and CTCF access to its cognate sites in promoters of differentially expressed genes

Authors: Andrew VonHandorf, Francisco Javier Sánchez-Martín, Jacek Biesiada, Hongxia Zhang, Xiang Zhang, Mario Medvedovic, Alvaro Puga

Source: Epigenetics, Vol 13, Iss 4, Pp 363-375 (2018)

Subject Terms: chromatin organization, nucleosome architecture, atac-seq, ctcf, hexavalent chromium, transcription, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1559-2294; https://doaj.org/toc/1559-2308

Access URL: https://doaj.org/article/02468d7435544d25936f1b1370684b05

Identification of sex-specific DNA methylation changes driven by specific chemicals in cord blood in a Faroese birth cohort

Authors: Yuet-Kin Leung, Bin Ouyang, Liang Niu, Changchun Xie, Jun Ying, Mario Medvedovic, Aimin Chen, Pal Weihe, Damaskini Valvi, Philippe Grandjean, Shuk-Mei Ho

Source: Epigenetics, Vol 13, Iss 3, Pp 290-300 (2018)

Subject Terms: 450k, beadchips, pcb105, hcb, hexachlorobenzene, polychlorinated biphenyls, gender difference, x-chromosome, pfos, ddt, pops, persistent organic pollutants, epigenetics, epidemiology, cord blood, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1559-2294; https://doaj.org/toc/1559-2308

Access URL: https://doaj.org/article/7bdb68b0c0b241e6b71d1c4882914b6c

Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration

Authors: Wei Huang, Yuliang Feng, Jialiang Liang, Hao Yu, Cheng Wang, Boyu Wang, Mingyang Wang, Lin Jiang, Wei Meng, Wenfeng Cai, Mario Medvedovic, Jenny Chen, Christian Paul, W. Sean Davidson, Sakthivel Sadayappan, Peter J. Stambrook, Xi-Yong Yu, Yigang Wang

Source: Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/b31199b519cc42139b0e79ff4459abd5

GRcalculator: an online tool for calculating and mining dose–response data

Authors: Nicholas A. Clark, Marc Hafner, Michal Kouril, Elizabeth H. Williams, Jeremy L. Muhlich, Marcin Pilarczyk, Mario Niepel, Peter K. Sorger, Mario Medvedovic

Source: BMC Cancer, Vol 17, Iss 1, Pp 1-11 (2017)

Subject Terms: GR metrics, GR50, GRmax, Data analysis, Web interface, Dose response, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-017-3689-3; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/4357f58f6bbf40c38dbaa4f40d80a26b

RNA SEQ Analysis Indicates that the AE3 Cl−/HCO3 − Exchanger Contributes to Active Transport-Mediated CO2 Disposal in Heart

Authors: Kanimozhi Vairamani, Hong-Sheng Wang, Mario Medvedovic, John N. Lorenz, Gary E. Shull

Source: Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/a36ff633f7eb4c8c93650c8f1bfceaa9

Comparability of the small RNA secretome across human biofluids concomitantly collected from healthy adults.

Authors: Scott M Langevin, Damaris Kuhnell, Jacek Biesiada, Xiang Zhang, Mario Medvedovic, Glenn G Talaska, Katherine A Burns, Susan Kasper

Source: PLoS ONE, Vol 15, Iss 4, p e0229976 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/686e49f905404f158f3101bb334904f5

The Development of Spasmolytic Polypeptide/TFF2-Expressing Metaplasia (SPEM) During Gastric Repair Is Absent in the Aged StomachSummary

Authors: Amy C. Engevik, Rui Feng, Eunyoung Choi, Shana White, Nina Bertaux-Skeirik, Jing Li, Maxime M. Mahe, Eitaro Aihara, Li Yang, Betsy DiPasquale, Sunghee Oh, Kristen A. Engevik, Andrew S. Giraud, Marshall H. Montrose, Mario Medvedovic, Michael A. Helmrath, James R. Goldenring, Yana Zavros

Source: Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 5, Pp 605-624 (2016)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X16300443; https://doaj.org/toc/2352-345X

Access URL: https://doaj.org/article/32c7d54435e74b8aa0fa7d00b9ae7963

Interleukin-22 levels are increased in gastrointestinal graft-versus-host disease in children

Authors: Dana T. Lounder, Pooja Khandelwal, Nicholas J. Gloude, Christopher E. Dandoy, Sonata Jodele, Mario Medvedovic, Lee A. Denson, Adam Lane, Kelly Lake, Bridget Litts, Alyss Wilkey, Stella M. Davies

Source: Haematologica, Vol 103, Iss 10 (2018)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/8643; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/060c3c08edb64fd68c41927bf5f3c622

Loss of IκB kinase β promotes myofibroblast transformation and senescence through activation of the ROS-TGFβ autocrine loop

Authors: Liang Chen, Zhimin Peng, Qinghang Meng, Maureen Mongan, Jingcai Wang, Maureen Sartor, Jing Chen, Liang Niu, Mario Medvedovic, Winston Kao, Ying Xia

Source: Protein & Cell, Vol 7, Iss 5, Pp 338-350 (2016)

Subject Terms: IkB kinase β (IKKβ), nuclear factor κB (NF-κB), transforming growth factors β (TGFβ), reactive oxygen species (ROS), myofibroblast, senescence, Cytology, QH573-671, Animal biochemistry, QP501-801

File Description: electronic resource

Relation: http://link.springer.com/article/10.1007/s13238-015-0241-6; https://doaj.org/toc/1674-800X; https://doaj.org/toc/1674-8018

Access URL: https://doaj.org/article/3ec46300fa9044e9b73b987e7366ed1b

Rhinovirus infection results in stronger and more persistent genomic dysregulation: Evidence for altered innate immune response in asthmatics at baseline, early in infection, and during convalescence.

Authors: Peter W Heymann, Huyen-Tran Nguyen, John W Steinke, Ronald B Turner, Judith A Woodfolk, Thomas A E Platts-Mills, Lisa Martin, Hua He, Jocelyn Biagini Myers, Mark Lindsey, Umasundari Sivaprasad, Mario Medvedovic, Naim Mahi, Holliday Carper, Deborah D Murphy, James Patrie, Gurjit K Khurana Hershey

Source: PLoS ONE, Vol 12, Iss 5, p e0178096 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5446117?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/59f18bb07a9240b1807758a7d36ecfcc

Correction: IL-31-Driven Skin Remodeling Involves Epidermal Cell Proliferation and Thickening That Lead to Impaired Skin-Barrier Function.

Authors: Brijendra Singh, Anil G Jegga, Kumar S Shanmukhappa, Ramakrishna Edukulla, Gurjit Kaur Khurana Hershey, Mario Medvedovic, Stacey R Dillon, Satish K Madala

Source: PLoS ONE, Vol 12, Iss 1, p e0170446 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5256880?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/42749d9088f54048834c96533886ade3

Gene Expression Profiling Identifies Lobe-Specific and Common Disruptions of Multiple Gene Networks in Testosterone-Supported, 17β-Estradiol- or Diethylstilbestrol-Induced Prostate Dysplasia in Noble Rats

Authors: Neville N.C. Tam, Carol Ying-Ying Szeto, Maureen A. Sartor, Mario Medvedovic, Shuk-Mei Ho

Source: Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 1, Pp 20-40 (2008)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558608801091; https://doaj.org/toc/1476-5586; https://doaj.org/toc/1522-8002

Access URL: https://doaj.org/article/8815ca5289274000aff7d599b39ad06f