Targeting CDK9 in Cancer: An Integrated Approach of Combining In Silico Screening with Experimental Validation for Novel Degraders

Authors: Mahesh Koirala, Mario DiPaola

Source: Current Issues in Molecular Biology, Vol 46, Iss 3, Pp 1713-1730 (2024)

Subject Terms: cancer, protein degradation, degraders, drug discovery, PROTAC, CDK9, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1467-3045/46/3/111; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

Access URL: https://doaj.org/article/f783286520344c43ac6d38cb2adfc5ad

Overcoming Cancer Resistance: Strategies and Modalities for Effective Treatment

Authors: Mahesh Koirala, Mario DiPaola

Source: Biomedicines, Vol 12, Iss 8, p 1801 (2024)

Subject Terms: cancer drug resistance, targeted protein degradation, immunotherapy combinations, precision medicine, novel drug delivery systems, PROTACs, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/12/8/1801; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/5535ea3c7c7d46dab378ce2791594e05

A new ChEMBL dataset for the similarity-based target fishing engine FastTargetPred: Annotation of an exhaustive list of linear tetrapeptides

Authors: Shivalika Tanwar, Patrick Auberger, Germain Gillet, Mario DiPaola, Katya Tsaioun, Bruno O. Villoutreix

Source: Data in Brief, Vol 42, Iss , Pp 108159- (2022)

Subject Terms: Peptide, Virtual screening, Drug discovery, Target prediction, Computer applications to medicine. Medical informatics, R858-859.7, Science (General), Q1-390

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352340922003638; https://doaj.org/toc/2352-3409

Access URL: https://doaj.org/article/6e535296d326447eb4efea2ac8a595bb