Genomic and immune determinants of resistance to daratumumab-based therapy in relapsed refractory multiple myeloma

Authors: Bachisio Ziccheddu, Claudia Giannotta, Mattia D’Agostino, Giuseppe Bertuglia, Elona Saraci, Stefania Oliva, Elisa Genuardi, Marios Papadimitriou, Benjamin Diamond, Paolo Corradini, David Coffey, Ola Landgren, Niccolò Bolli, Benedetto Bruno, Mario Boccadoro, Massimo Massaia, Francesco Maura, Alessandra Larocca

Source: Blood Cancer Journal, Vol 14, Iss 1, Pp 1-12 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2044-5385

Access URL: https://doaj.org/article/a0836646950848c8a7696721b96ea559

Additional copies of 1q negatively impact the outcome of multiple myeloma patients and induce transcriptomic deregulation in malignant plasma cells

Authors: Mattia D’Agostino, Delia Rota-Scalabrini, Angelo Belotti, Luca Bertamini, Maddalena Arigoni, Giovanni De Sabbata, Giuseppe Pietrantuono, Anna Pascarella, Patrizia Tosi, Francesco Pisani, Norbert Pescosta, Marina Ruggeri, Jennifer Rogers, Martina Olivero, Mariagrazia Garzia, Piero Galieni, Ombretta Annibali, Federico Monaco, Anna Marina Liberati, Salvatore Palmieri, Paola Stefanoni, Elena Zamagni, Benedetto Bruno, Raffaele Adolfo Calogero, Mario Boccadoro, Pellegrino Musto, Francesca Gay

Source: Blood Cancer Journal, Vol 14, Iss 1, Pp 1-9 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2044-5385

Access URL: https://doaj.org/article/de9018c7e2514cbf84b93ad1e4029993

Belantamab mafodotin in triple‐refractory multiple myeloma patients: A retro‐prospective observational study in Italy

Authors: Francesca Fazio, Maria Teresa Petrucci, Laura Corvatta, Alfonso Piciocchi, Roberta Della Pepa, Paola Tacchetti, Maurizio Musso, Renato Zambello, Angelo Belotti, Sara Bringhen, Elisabetta Antonioli, Concetta Conticello, Nicola Di Renzo, Valerio De Stefano, Pellegrino Musto, Barbara Gamberi, Daniele Derudas, Mario Boccadoro, Massimo Offidani, Sonia Morè

Source: eJHaem, Vol 5, Iss 3, Pp 485-493 (2024)

Subject Terms: belantamab mafodotin, multiple myeloma, real‐world, Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/2688-6146

Access URL: https://doaj.org/article/7725cc7a33b84acb8c1ed168063ccd72

A prospective, multicenter study on hematopoietic stemcell mobilization with cyclophosphamide plus granulocyte colony-stimulating factor and ‘on-demand’ plerixafor in multiple myeloma patients treated with novel agents

Authors: Roberto Mina, Maria Teresa Petrucci, Francesca Bonello, Velia Bongarzoni, Riccardo Saccardi, Giuseppe Bertuglia, Andrea Mengarelli, Andrea Spadaro, Chiara Lisi, Paola Curci, Roberto Massimo Lemoli, Stelvio Ballanti, Rita Floris, Luca Cupelli, Patrizia Tosi, Attilio Olivieri, Delia Rota-Scalabrini, Clotilde Cangialosi, Chiara Nozzoli, Barbara Anaclerico, Francesca Fazio, Benedetto Bruno, Katia Mancuso, Paolo Corradini, Giuseppe Milone, Mario Boccadoro

Source: Haematologica, Vol 109, Iss 5 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/11344; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/9166e5bc73e84f42bc5fc785d6d557e5

P1680: HEALTH-RELATED QUALITY OF LIFE IN TRANSPLANT-INELIGIBLE REAL-LIFE MULTIPLE MYELOMA PATIENTS TREATED WITH FIXED-DURATION BORTEZOMIB-MELPHALAN-PREDNISONE VS. CONTINUOUS LENALIDOMIDE-DEXAMETHASONE

Authors: Mattia D’agostino, Sara Bringhen, Nicola Giuliani, Elisabetta Antonioli, Renato Zambello, Francesco Cattel, Roberto Ria, Alessandro Allegra, Giovanna Leonardi, Angelo Belotti, Piero Galieni, Gloria Margiotta-Casaluci, Maria Cantonetti, Valentina Cotugno, Barbara Gamberi, Fabrizio Pane, Anna Marina Liberati, Patrizia Tosi, Maide Maria Cavalli, Donato Mannina, Giulia Benevolo, Silvia Mangiacavalli, Andrea Evangelista, Giovannino Ciccone, Mario Boccadoro, Benedetto Bruno, Alessandra Larocca

Source: HemaSphere, Vol 7, p e993869a (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/01.HS9.0000973592.99386.9a; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/81479fd2b8f74f5088b1123fe168121b

P804: PLASMA CELL LEUKEMIA-LIKE TRANSCRIPTOME OF BONE MARROW PLASMA CELLS AND CIRCULATING TUMOR CELL LEVELS IN PERIPHERAL BLOOD COMPLEMENTARILY DEFINE HIGH-RISK IN NEWLY DIAGNOSED MULTIPLE MYELOMA

Authors: Mattia D’agostino, Davine Hofste Op Bruinink, Mark van Duin, Delia Rota-Scalabrini, Luca Bertamini, Rowan Kuiper, Angelo Belotti, Vincenzo Marasco, Stefania Oliva, Elena Rivolti, Jennifer Rogers, Roberto Mina, Mariella Grasso, Antonio Ledda, Massimo Offidani, Monica Galli, Michele Cavo, Annemiek Broijl, Pellegrino Musto, Benedetto Bruno, Mario Boccadoro, Pieter Sonneveld, Francesca Gay

Source: HemaSphere, Vol 7, p e36094ab (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/01.HS9.0000970120.36094.ab; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/3b796f80d4e14f24afec4a2aa1b32606

P895: DARATUMUMAB PLUS POMALIDOMIDE AND DEXAMETHASONE (DPD) IN PATIENTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA AND 17P DELETION: UPDATED ANALYSIS OF THE DEDALO PHASE II TRIAL

Authors: Vittorio Montefusco, Anna Maria Cafro, Gloria Margiotta-Casaluci, Francesca Patriarca, Roberto Mina, Mattia D’agostino, Anna Benedetta Dalla Palma, Rita Rizzi, Angelo Genua, Francesca Fazio, Laura Paris, Angelo Belotti, Ilaria Rizzello, Concetta Conticello, Carmelo Carlo-Stella, Mario Boccadoro

Source: HemaSphere, Vol 7, p e729785d (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/01.HS9.0000970484.72978.5d; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/c18d8975f59b4d80b1aa597a9557ee91

Ixazomib-based induction regimens plus ixazomib maintenance in transplant-ineligible, newly diagnosed multiple myeloma: the phase II, multi-arm, randomized UNITO-EMN10 trial

Authors: Roberto Mina, Antonietta Pia Falcone, Sara Bringhen, Anna Marina Liberati, Norbert Pescosta, Maria Teresa Petrucci, Giovannino Ciccone, Andrea Capra, Francesca Patriarca, Delia Rota-Scalabrini, Francesca Bonello, Caterina Musolino, Michele Cea, Renato Zambello, Paola Tacchetti, Angelo Belotti, Claudia Cellini, Laura Paris, Mariella Grasso, Sara Aquino, Lorenzo De Paoli, Giovanni De Sabbata, Stelvio Ballanti, Massimo Offidani, Mario Boccadoro, Federico Monaco, Paolo Corradini, Alessandra Larocca

Source: Blood Cancer Journal, Vol 11, Iss 12, Pp 1-5 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2044-5385

Access URL: https://doaj.org/article/85d07ceb4ffb4350a7da29ebc2f8331e

Carfilzomib, Pomalidomide, and Dexamethasone As Second-line Therapy for Lenalidomide-refractory Multiple Myeloma

Authors: Pieter Sonneveld, Sonja Zweegman, Michele Cavo, Kazem Nasserinejad, Annemiek Broijl, Rosella Troia, Ludek Pour, Sandra Croockewit, Paolo Corradini, Francesca Patriarca, Kalung Wu, Jolanda Droogendijk, Gerard Bos, Roman Hajek, Maria Teresa Petrucci, Paula Ypma, Nicholas Zojer, Monique C. Minnema, Mario Boccadoro

Source: HemaSphere, Vol 6, Iss 10, p e786 (2022)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/HS9.0000000000000786; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/98b6b44e179b444cb4be980901930363

Minimal residual disease assessment by multiparameter flow cytometry in transplant-eligible myeloma in the EMN02/HOVON 95 MM trial

Authors: Stefania Oliva, Davine Hofste op Bruinink, Lucie Rihova, Mattia D’Agostino, Lucia Pantani, Andrea Capra, Bronno van der Holt, Rossella Troia, Maria Teresa Petrucci, Tania Villanova, Pavla Vsianska, Romana Jugooa, Claudia Brandt-Hagens, Milena Gilestro, Massimo Offidani, Rossella Ribolla, Monica Galli, Roman Hajek, Francesca Gay, Michele Cavo, Paola Omedé, Vincent H. J. van der Velden, Mario Boccadoro, Pieter Sonneveld

Source: Blood Cancer Journal, Vol 11, Iss 6, Pp 1-9 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2044-5385

Access URL: https://doaj.org/article/fff4989bfcb448fa8d1e3442a6743211

Octogenarian newly diagnosed multiple myeloma patients without geriatric impairments: the role of age >80 in the IMWG frailty score

Authors: Mattia D’Agostino, Alessandra Larocca, Massimo Offidani, Anna Marina Liberati, Gianluca Gaidano, Maria Teresa Petrucci, Daniele Derudas, Andrea Capra, Renato Zambello, Nicola Cascavilla, Paolo de Fabritiis, Vanessa Innao, Francesca Bonello, Francesca Patriarca, Giulia Benevolo, Nicola Giuliani, Gabriele Aitoro, Tommasina Guglielmelli, Francesco Di Raimondo, Paolo Corradini, Pellegrino Musto, Roman Hájek, Pieter Sonneveld, Mario Boccadoro, Sara Bringhen

Source: Blood Cancer Journal, Vol 11, Iss 4, Pp 1-5 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2044-5385

Access URL: https://doaj.org/article/2bfcf6a98cdd434897d6e066fb202482

Survival Risk Scores for Real-Life Relapsed/Refractory Multiple Myeloma Patients Receiving Elotuzumab or Carfilzomib In Combination With Lenalidomide and Dexamethasone as Salvage Therapy: Analysis of 919 Cases Outside Clinical Trials

Authors: Fortunato Morabito, Elena Zamagni, Concetta Conticello, Vincenzo Pavone, Salvatore Palmieri, Sara Bringhen, Monica Galli, Silvia Mangiacavalli, Daniele Derudas, Elena Rossi, Roberto Ria, Lucio Catalano, Paola Tacchetti, Giuseppe Mele, Iolanda Donatella Vincelli, Enrica Antonia Martino, Ernesto Vigna, Antonella Bruzzese, Francesco Mendicino, Cirino Botta, Anna Mele, Lucia Pantani, Serena Rocchi, Bruno Garibaldi, Nicola Cascavilla, Stelvio Ballanti, Giovanni Tripepi, Ferdinando Frigeri, Antonetta Pia Falcone, Clotilde Cangialosi, Giovanni Reddiconto, Giuliana Farina, Marialucia Barone, Ilaria Rizzello, Enrico Iaccino, Selena Mimmi, Paola Curci, Barbara Gamberi, Pellegrino Musto, Valerio De Stefano, Maurizio Musso, Maria Teresa Petrucci, Massimo Offidani, Francesco Di Raimondo, Mario Boccadoro, Michele Cavo, Antonino Neri, Massimo Gentile

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: multiple myeloma, prognosis, prognostic score, carfilzomib, elotuzumab, lenalidomide, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.890376/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/558f55d38b4c4a8a985194fbba17f62d

Extended half‐life rFIX in major surgery—How to improve clinical practice: An intraindividual comparison

Authors: Federica Valeri, Jacopo Agnelli Giacchello, Cristina Dainese, Alessandra Valpreda, Barbara Montaruli, Enrico Dosio, Mario Boccadoro, Alessandra Borchiellini

Source: Clinical Case Reports, Vol 8, Iss 3, Pp 531-534 (2020)

Subject Terms: extended half‐life FIX, hemophilia B, major surgery, orthopedic, pharmacokinetic, real‐life experience, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2050-0904

Access URL: https://doaj.org/article/684d04ee9105473b957e80cd9079173e

Place in therapy of innovative drugs in multiple myeloma in 2021 and 2023 according to an expert panel Delphi consensus

Authors: Mario Boccadoro, Patrizia Berto, Sara Bringhen, Elena Zamagni, Patrizia Tosi, Nicola Cascavilla, Nicola Giuliani, Donato Mannina, Renato Zambello, Francesca Patriarca, Vittorio Montefusco, Mariella Grasso, Francesco Di Raimondo, Massimo Offidani, Maria Teresa Petrucci, Pellegrino Musto

Source: Global & Regional Health Technology Assessment, Vol 8 (2021)

Subject Terms: Delphi Panel, European Myeloma Network, Monoclonal antibodies, Multiple myeloma, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://journals.aboutscience.eu/index.php/grhta/article/view/2245; https://doaj.org/toc/2284-2403; https://doaj.org/toc/2283-5733

Access URL: https://doaj.org/article/b3552ba73db946fea0cb3e0ef29316cc

2021 European Myeloma Network review and consensus statement on smoldering multiple myeloma: how to distinguish (and manage) Dr. Jekyll and Mr. Hyde

Authors: Pellegrino Musto, Monika Engelhardt, Jo Caers, Niccolo’ Bolli, Martin Kaiser, Niels van de Donk, Evangelos Terpos, Annemiek Broijl, Carlos Fernández de Larrea, Francesca Gay, Hartmut Goldschmidt, Roman Hajek, Annette Juul Vangsted, Elena Zamagni, Sonja Zweegman, Michele Cavo, Meletios Dimopoulos, Hermann Einsele, Heinz Ludwig, Giovanni Barosi, Mario Boccadoro, Maria-Victoria Mateos, Pieter Sonneveld, Jesus San Miguel

Source: Haematologica, Vol 106, Iss 11 (2021)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/10333; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/cf3a4b9480b34ab1a0ab540a0e81ad4b

European Myeloma Network perspective on CAR T-Cell therapies for multiple myeloma

Authors: Benedetto Bruno, Ralph Wäsch, Monika Engelhardt, Francesca Gay, Luisa Giaccone, Mattia D’Agostino, Luis-Gerardo Rodríguez-Lobato, Sophia Danhof, Nico Gagelmann, Nicolaus Kröger, Rakesh Popat, Niels W.C.J. van de Donk, Evangelos Terpos, Meletios A. Dimopoulos, Pieter Sonneveld, Hermann Einsele, Mario Boccadoro

Source: Haematologica, Vol 106, Iss 8 (2021)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/10228; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/dfc7ce3c93f249d9a7371b573a30ca31

Multiple Myeloma: EHA-ESMO Clinical Practice Guidelines for Diagnosis, Treatment and Follow-up

Authors: Meletios A. Dimopoulos, Philippe Moreau, Evangelos Terpos, María-Victoria Mateos, Sonja Zweegman, Gordon Cook, Michel Delforge, Roman Hájek, Fredrik Schjesvold, Michele Cavo, Hartmut Goldschmidt, Thierry Facon, Hermann Einsele, Mario Boccadoro, Jesús San-Miguel, Pieter Sonneveld, Ulrich Mey, on behalf of the EHA Guidelines Committee and the ESMO Guidelines Committee

Source: HemaSphere, Vol 5, Iss 2, p e528 (2021)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/HS9.0000000000000528; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/c1865baaad2e4205a7ac4ccb6e05bd2a

Immune Dysfunctions and Immune-Based Therapeutic Interventions in Chronic Lymphocytic Leukemia

Authors: Valentina Griggio, Francesca Perutelli, Chiara Salvetti, Elia Boccellato, Mario Boccadoro, Candida Vitale, Marta Coscia

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: chronic lymphocytic leukemia, immune dysfunction, immunotherapy, immunomodulation, targeted therapy, cellular therapy, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2020.594556/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/fc36fd8e713a420b95060518defba5fe

Standardization of flow cytometric minimal residual disease assessment in international clinical trials. A feasibility study from the European Myeloma Network

Authors: Davine Hofste op Bruinink, Stefania Oliva, Lucie Rihova, Alexander Schmitz, Milena Gilestro, Jeroen te Marvelde, Romana Kralova, Helle Høholt, Annemiek Broijl, Hans Erik Johnsen, Roman Hajek, Mario Boccadoro, Pieter Sonneveld, Paola Omedè, Vincent H.J. van der Velden

Source: Haematologica, Vol 106, Iss 5 (2020)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/10039; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/2e62a93c1e5a446097540e148434f786

Lenalidomide-based induction and maintenance in elderly newly diagnosed multiple myeloma patients: updated results of the EMN01 randomized trial

Authors: Sara Bringhen, Mattia D’Agostino, Laura Paris, Stelvio Ballanti, Norbert Pescosta, Stefano Spada, Sara Pezzatti, Mariella Grasso, Delia Rota-Scalabrini, Luca De Rosa, Vincenzo Pavone, Giulia Gazzera, Sara Aquino, Marco Poggiu, Armando Santoro, Massimo Gentile, Luca Baldini, Maria Teresa Petrucci, Patrizia Tosi, Roberto Marasca, Claudia Cellini, Antonio Palumbo, Patrizia Falco, Roman Hájek, Mario Boccadoro, Alessandra Larocca

Source: Haematologica, Vol 105, Iss 7 (2020)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/9945; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/9b964beaa1304beda086763a5297de0d