The activity of a PI3K δ-sparing inhibitor, MEN1611, in non-small cell lung cancer cells with constitutive activation of the PI3K/AKT/mTOR pathway

Authors: Giuliana Papoff, Dario Presutti, Valentina Fustaino, Andrea Parente, Clelia Calandriello, Stefano Alemà, Ferdinando Scavizzi, Marcello Raspa, Giuseppe Merlino, Massimiliano Salerno, Mario Bigioni, Monica Binaschi, Giovina Ruberti

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: NSCLC, PI3K inhibitor, EGFR-TKIs, drug-resistance, combination therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1283951/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/280dc1bb29754467928f7742e2628ec3

Targeting CD205 with the antibody drug conjugate MEN1309/OBT076 is an active new therapeutic strategy in lymphoma models

Authors: Eugenio Gaudio, Chiara Tarantelli, Filippo Spriano, Francesca Guidetti, Giulio Sartori, Roberta Bordone, Alberto J. Arribas, Luciano Cascione, Mario Bigioni, Giuseppe Merlino, Alessio Fiascarelli, Alessandro Bressan, Afua Adjeiwaa Mensah, Gaetanina Golino, Renzo Lucchini, Elena Bernasconi, Davide Rossi, Emanuele Zucca, Georg Stussi, Anastasios Stathis, Robert S. Boyd, Rachel L. Dusek, Arnima Bisht, Nickolas Attanasio, Christian Rohlff, Andrea Pellacani, Monica Binaschi, Francesco Bertoni

Source: Haematologica, Vol 105, Iss 11 (2020)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/9601; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/fd52bf5cbc7f444ba1538b1b0e104dc7

MicroRNA-130b Promotes Tumor Development and Is Associated with Poor Prognosis in Colorectal Cancer

Authors: Tommaso Colangelo, Alessandra Fucci, Carolina Votino, Lina Sabatino, Massimo Pancione, Carmelo Laudanna, Monica Binaschi, Mario Bigioni, Carlo Alberto Maggi, Domenico Parente, Nicola Forte, Vittorio Colantuoni

Source: Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 9, Pp 1086-1099 (2013)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S147655861380019X; https://doaj.org/toc/1476-5586; https://doaj.org/toc/1522-8002

Access URL: https://doaj.org/article/ad750e8f69c4466eab1c952d380d1042

Role of NK-1 and NK-2 tachykinin receptor antagonism on the growth of human breast carcinoma cell line MDA-MB-231.

Authors: Mario Bigioni

Source: Anti-Cancer Drugs; Nov2005, Vol. 16 Issue 10, p1083-1089, 7p

CD137 and CD137 ligand constitutively coexpressed on human T and B leukemia cells signal proliferation and survival.

Authors: Carla Palma, Monica Binaschi, Mario Bigioni, Carlo Alberto Maggi, Cristina Goso

Source: International Journal of Cancer; 1/20/2004, Vol. 108 Issue 3, p390-398, 9p

Subject Terms: TUMOR necrosis factors, T cells, ANTIGENS