Guidance for pediatric use in prescription information for novel medicinal products in the EU and the US.

Authors: Helle Christiansen, Marie L De Bruin, Sven Frokjaer, Christine E Hallgreen

Source: PLoS ONE, Vol 17, Iss 4, p e0266353 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/92fac2e94a324bc381bf628194448c73

Diabetes and Breast Cancer Subtypes.

Authors: Heleen K Bronsveld, Vibeke Jensen, Pernille Vahl, Marie L De Bruin, Sten Cornelissen, Joyce Sanders, Anssi Auvinen, Jari Haukka, Morten Andersen, Peter Vestergaard, Marjanka K Schmidt

Source: PLoS ONE, Vol 12, Iss 1, p e0170084 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5226802?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/a05a6667875341eca43b7d2fa25e2f96

Resting heart rate is a risk factor for mortality in chronic obstructive pulmonary disease, but not for exacerbations or pneumonia.

Authors: Miriam J Warnier, Frans H Rutten, Anthonius de Boer, Arno W Hoes, Marie L De Bruin

Source: PLoS ONE, Vol 9, Iss 8, p e105152 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4144884?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/19d71f4a6eb04d0a84970037b196a358

Number of patients studied prior to approval of new medicines: a database analysis.

Authors: Ruben G Duijnhoven, Sabine M J M Straus, June M Raine, Anthonius de Boer, Arno W Hoes, Marie L De Bruin

Source: PLoS Medicine, Vol 10, Iss 3, p e1001407 (2013)

Subject Terms: Medicine

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3601954?pdf=render; https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676

Access URL: https://doaj.org/article/f500dd85e4fa4007aa1fd7c332409e69

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Mandatory requirements for pediatric drug development in the EU and the US for novel drugs—A comparative study

Authors: Helle Christiansen, Marie L. De Bruin, Christine E. Hallgreen

Source: Frontiers in Medicine, Vol 9 (2022)

Subject Terms: EU Pediatric Regulation, Pediatric Research Equity Act, legislation, pediatric drug development, EMA, FDA, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2022.1009432/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/76ced31c8dcb40fbbbeb8b58b790bd4c

Challenges and Opportunities for Companies to Build HTA/Payer Perspectives Into Drug Development Through the Use of a Dynamic Target Product Profile

Authors: Ting Wang, Neil McAuslane, Wim G. Goettsch, Hubert G. M. Leufkens, Marie L. De Bruin

Source: Frontiers in Pharmacology, Vol 13 (2022)

Subject Terms: drug development, evidence generation, health technology assessment (HTA), target product profile (TPP), reimbursement, company strategies, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.948161/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/d25677fa677b4d608b735843d9929e4a

The association of diabetes mellitus and insulin treatment with expression of insulin-related proteins in breast tumors

Authors: Heleen K. Bronsveld, Marie L. De Bruin, Jelle Wesseling, Joyce Sanders, Ingrid Hofland, Vibeke Jensen, Marloes T. Bazelier, Bas ter Braak, Anthonius de Boer, Peter Vestergaard, Marjanka K. Schmidt

Source: BMC Cancer, Vol 18, Iss 1, Pp 1-11 (2018)

Subject Terms: Insulin, Insulin growth factor 1 receptor, Diabetes mellitus, Breast cancer, PI3K pathway, MAPK pathway, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-018-4072-8; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/694fef545aba4c049b75eb8ee1c082eb

Evidence Synthesis in Harm Assessment of Medicines Using the Example of Rosiglitazone and Myocardial Infarction

Authors: Charlotte Rietbergen, Gudrun Stefansdottir, Hubert G. Leufkens, Mirjam J. Knol, Marie L. De Bruin, Irene Klugkist

Source: Frontiers in Medicine, Vol 4 (2018)

Subject Terms: evidence synthesis, Bayesian inference, informative priors, benefit vs. risk, safety, Medicine (General), R5-920

File Description: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fmed.2017.00228/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/508d74a5a6fc4adebf7fe2c61f2dbca1