Effect of 3BNC117 and romidepsin on the HIV-1 reservoir in people taking suppressive antiretroviral therapy (ROADMAP): a randomised, open-label, phase 2A trial

Authors: Henning Gruell, MD, Jesper D Gunst, MD, Yehuda Z Cohen, MD, Marie H Pahus, Jakob J Malin, MD, Martin Platten, MD, Katrina G Millard, RN, Martin Tolstrup, PhD, R Brad Jones, PhD, Winnifer D Conce Alberto, Julio C C Lorenzi, PhD, Thiago Y Oliveira, PhD, Tim Kümmerle, MD, Isabelle Suárez, MD, Cecilia Unson-O'Brien, PhD, Lilian Nogueira, PhD, Rikke Olesen, PhD, Lars Østergaard, ProfMD, Henrik Nielsen, ProfMD, Clara Lehmann, MD, Michel C Nussenzweig, ProfMD, Gerd Fätkenheuer, ProfMD, Florian Klein, ProfMD, Marina Caskey, ProfMD, Ole S Søgaard, ProfMD

Source: The Lancet Microbe, Vol 3, Iss 3, Pp e203-e214 (2022)

Subject Terms: Medicine (General), R5-920, Microbiology, QR1-502

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666524721002391; https://doaj.org/toc/2666-5247

Access URL: https://doaj.org/article/b572a4bc81f74c27b4e7e697acac132e

SARS-CoV-2 elicits robust adaptive immune responses regardless of disease severity

Authors: Stine SF Nielsen, Line K Vibholm, Ida Monrad, Rikke Olesen, Giacomo S Frattari, Marie H Pahus, Jesper F Højen, Jesper D Gunst, Christian Erikstrup, Andreas Holleufer, Rune Hartmann, Lars Østergaard, Ole S Søgaard, Mariane H Schleimann, Martin Tolstrup

Source: EBioMedicine, Vol 68, Iss , Pp 103410- (2021)

Subject Terms: SARS-CoV-2, COVID-19, Antibody, CD8+ T-cell, Immune response, Adaptive, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396421002036; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/eb4b5ba920414fcc8e791c8269b8081f

Efficacy of the TMPRSS2 inhibitor camostat mesilate in patients hospitalized with Covid-19-a double-blind randomized controlled trial.

Authors: Jesper D. Gunst, Nina B. Staerke, Marie H. Pahus, Lena H. Kristensen, Jacob Bodilsen, Nicolai Lohse, Lars S. Dalgaard, Dorthe Brønnum, Ole Fröbert, Bo Hønge, Isik S. Johansen, Ida Monrad, Christian Erikstrup, Regitze Rosendal, Emil Vilstrup, Theis Mariager, Dorthe G. Bove, Rasmus Offersen, Shakil Shakar, Sara Cajander, Nis P. Jørgensen, Sajitha S. Sritharan, Peter Breining, Søren Jespersen, Klaus L. Mortensen, Mads L. Jensen, Lilian Kolte, Giacomo S. Frattari, Carsten S. Larsen, Merete Storgaard, Lars P. Nielsen, Martin Tolstrup, Eva A. Sædder, Lars J. Østergaard, Hien T.T. Ngo, Morten H. Jensen, Jesper F. Højen, Mads Kjolby, Ole S. Søgaard

Source: EClinicalMedicine, Vol 35, Iss , Pp 100849- (2021)

Subject Terms: Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589537021001292; https://doaj.org/toc/2589-5370

Access URL: https://doaj.org/article/c25557f47802410fa852f84ca0e3b0e0

SARS-CoV-2 persistence is associated with antigen-specific CD8 T-cell responses

Authors: Line K. Vibholm, Stine S.F. Nielsen, Marie H. Pahus, Giacomo S. Frattari, Rikke Olesen, Rebecca Andersen, Ida Monrad, Anna H.F. Andersen, Michelle M. Thomsen, Christina V. Konrad, Sidsel D. Andersen, Jesper F. Højen, Jesper D. Gunst, Lars Østergaard, Ole S. Søgaard, Mariane H. Schleimann, Martin Tolstrup

Source: EBioMedicine, Vol 64, Iss , Pp 103230- (2021)

Subject Terms: SARS-CoV-2, Persistent PCR positive, Immunology, Antibodies, CD8 T cell responses, Transmission, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396421000232; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/9683b9c8a27544d3aaed5a11e66730ee

Administration of broadly neutralizing anti-HIV-1 antibodies at ART initiation maintains long-term CD8+ T cell immunity

Authors: Miriam Rosás-Umbert, Jesper D. Gunst, Marie H. Pahus, Rikke Olesen, Mariane Schleimann, Paul W. Denton, Victor Ramos, Adam Ward, Natalie N. Kinloch, Dennis C. Copertino, Tuixent Escribà, Anuska Llano, Zabrina L. Brumme, R. Brad Jones, Beatriz Mothe, Christian Brander, Julie Fox, Michel C. Nussenzweig, Sarah Fidler, Marina Caskey, Martin Tolstrup, Ole S. Søgaard

Source: Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/ef639b4a891643dcb296cca780fd13c0