Analysis of ATG4C function in vivo

Authors: Tamargo-Gómez, Isaac, Martínez-García, Gemma G., Suárez, María F., Mayoral, Pablo, Bretones, Gabriel, Astudillo, Aurora, Prieto-Lloret, Jesús, Sveen, Christina, Fueyo, Antonio, Engedal, Nikolai, López-Otín, Carlos, Mariño, Guillermo

Source: Autophagy. 19(11):2912-2933

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194705557.0x000001&indx=1&recIds=ETOCvdc_100194705557.0x000001

Microglial phagocytosis dysfunction in stroke is driven by energy depletion and induction of autophagy

Authors: Beccari, Sol, Sierra-Torre, Virginia, Valero, Jorge, Pereira-Iglesias, Marta, García-Zaballa, Mikel, Soria, Federico N., De Las Heras-Garcia, Laura, Carretero-Guillen, Alejandro, Capetillo-Zarate, Estibaliz, Domercq, Maria, Huguet, Paloma R., Ramonet, David, Osman, Ahmed, Han, Wei, Dominguez, Cecilia, Faust, Travis E., Touzani, Omar, Pampliega, Olatz, Boya, Patricia, Schafer, Dorothy, Mariño, Guillermo, Canet-Soulas, Emmanuelle, Blomgren, Klas, Plaza-Zabala, Ainhoa, Sierra, Amanda

Source: Autophagy. 19(7):1952-1981

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185682519.0x000001&indx=1&recIds=ETOCvdc_100185682519.0x000001

Ambra1 haploinsufficiency in CD1 mice results in metabolic alterations and exacerbates age-associated retinal degeneration

Authors: Ramírez-Pardo, Ignacio, Villarejo-Zori, Beatriz, Jiménez-Loygorri, Juan Ignacio, Sierra-Filardi, Elena, Alonso-Gil, Sandra, Mariño, Guillermo, de la Villa, Pedro, Fitze, Patrick S, Fuentes, José Manuel, García-Escudero, Ramón, Ferrington, Deborah A., Gomez-Sintes, Raquel, Boya, Patricia

Source: Autophagy. 19(3):784-804

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176252607.0x000001&indx=1&recIds=ETOCvdc_100176252607.0x000001

Comparative genomics of mortal and immortal cnidarians unveils novel keys behind rejuvenation

Authors: Pascual-Torner, Maria, Carrero, Dido, Pérez-Silva, José G., Álvarez-Puente, Diana, Roiz-Valle, David, Bretones, Gabriel, Rodríguez, David, Maeso, Daniel, Mateo-González, Elena, Español, Yaiza, Mariño, Guillermo, Acuña, José Luis, Quesada, Víctor, López-Otína, Carlos

Source: Proceedings of the National Academy of Sciences of the United States of America, 2022 Sep 01. 119(36), 1-8.

Access URL: https://www.jstor.org/stable/27206964

Relationship between PMN-endothelium interactions, ROS production and Beclin-1 in type 2 diabetes

Authors: De Marañon, Aranzazu M., Iannantuoni, Francesca, Abad-Jiménez, Zaida, Canet, Francisco, Díaz-Pozo, Pedro, López-Domènech, Sandra, Jover, Ana, Morillas, Carlos, Mariño, Guillermo, Apostolova, Nadezda, Rocha, Milagros, Victor, Victor M.

Source: In Redox Biology July 2020 34

TDP-43 regulates LC3ylation in neural tissue through ATG4B cryptic splicing inhibition.

Authors: Torres, Pascual, Rico-Rios, Santiago, Ceron-Codorniu, Miriam, Santacreu-Vilaseca, Marta, Seoane-Miraz, David, Jad, Yahya, Ayala, Victòria, Mariño, Guillermo, Beltran, Maria, Miralles, Maria P., Andrés-Benito, Pol, Fernandez-Irigoyen, Joaquin, Santamaria, Enrique, López-Otín, Carlos, Soler, Rosa M., Povedano, Monica, Ferrer, Isidro, Pamplona, Reinald, Wood, Matthew J. A., Varela, Miguel A.

Source: Acta Neuropathologica; 9/21/2024, Vol. 148 Issue 1, p1-22, 22p

Subject Terms: SURVIVAL rate, NERVE tissue, MOTOR neurons, POST-translational modification, MICROTUBULE-associated proteins, MOTOR neuron diseases

Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism

Authors: Bárcena, Clea, Quirós, Pedro M., Durand, Sylvère, Mayoral, Pablo, Rodríguez, Francisco, Caravia, Xurde M., Mariño, Guillermo, Garabaya, Cecilia, Fernández-García, María Teresa, Kroemer, Guido, Freije, José M.P., López-Otín, Carlos

Source: In Cell Reports 28 August 2018 24(9):2392-2403

ATG4D role in mAtg8s delipidation and neuroprotection

Authors: Tamargo-Gómez, Isaac, Martínez-García, Gemma G., Suárez, María F., Fernández, Alvaro F., Mariño, Guillermo

Source: Autophagy. 17(6):1558-1560

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121595091.0x000001&indx=1&recIds=ETOCvdc_100121595091.0x000001

Aspirin Recapitulates Features of Caloric Restriction

Authors: Pietrocola, Federico, Castoldi, Francesca, Markaki, Maria, Lachkar, Sylvie, Chen, Guo, Enot, David P., Durand, Sylvere, Bossut, Noelie, Tong, Mingming, Malik, Shoaib A., Loos, Friedemann, Dupont, Nicolas, Mariño, Guillermo, Abdelkader, Nejma, Madeo, Frank, Maiuri, Maria Chiara, Kroemer, Romano, Codogno, Patrice, Sadoshima, Junichi, Tavernarakis, Nektarios, Kroemer, Guido

Source: In Cell Reports 27 February 2018 22(9):2395-2407

Autophagy‐linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS‐CoV‐2 entry into human cells

Authors: Ugalde, Alejandro P, Bretones, Gabriel, Rodríguez, David, Quesada, Víctor, Llorente, Francisco, Fernández‐Delgado, Raúl, Jiménez‐Clavero, Miguel Ángel, Vázquez, Jesús, Calvo, Enrique, Tamargo‐Gómez, Isaac, Mariño, Guillermo, Roiz‐Valle, David, Maeso, Daniel, Araujo‐Voces, Miguel, Español, Yaiza, Barceló, Carles, Freije, José MP, López‐Soto, Alejandro, López‐Otín, Carlos

Source: EMBO journal. 41(21)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185738596.0x000001&indx=1&recIds=ETOCvdc_100185738596.0x000001

Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance

Authors: Pietrocola, Federico, Pol, Jonathan, Vacchelli, Erika, Rao, Shuan, Enot, David P., Baracco, Elisa E., Levesque, Sarah, Castoldi, Francesca, Jacquelot, Nicolas, Yamazaki, Takahiro, Senovilla, Laura, Marino, Guillermo, Aranda, Fernando, Durand, Sylvère, Sica, Valentina, Chery, Alexis, Lachkar, Sylvie, Sigl, Verena, Bloy, Norma, Buque, Aitziber, Falzoni, Simonetta, Ryffel, Bernhard, Apetoh, Lionel, Di Virgilio, Francesco, Madeo, Frank, Maiuri, Maria Chiara, Zitvogel, Laurence, Levine, Beth, Penninger, Josef M., Kroemer, Guido

Source: In Cancer Cell 11 July 2016 30(1):147-160

Programmed mitophagy is essential for the glycolytic switch during cell differentiation

Authors: Esteban‐Martínez, Lorena, Sierra‐Filardi, Elena, McGreal, Rebecca S, Salazar‐Roa, María, Mariño, Guillermo, Seco, Esther, Durand, Sylvère, Enot, David, Graña, Osvaldo, Malumbres, Marcos, Cvekl, Ales, Cuervo, Ana María, Kroemer, Guido, Boya, Patricia

Source: EMBO journal. 36(12):1688-1706

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100077655046.0x000001&indx=1&recIds=ETOCvdc_100077655046.0x000001

Regulation of Autophagy by Cytosolic Acetyl-Coenzyme A

Authors: Mariño, Guillermo, Pietrocola, Federico, Eisenberg, Tobias, Kong, Yongli, Malik, Shoaib Ahmad, Andryushkova, Aleksandra, Schroeder, Sabrina, Pendl, Tobias, Harger, Alexandra, Niso-Santano, Mireia, Zamzami, Naoufal, Scoazec, Marie, Durand, Silvère, Enot, David P., Fernández, Álvaro F., Martins, Isabelle, Kepp, Oliver, Senovilla, Laura, Bauvy, Chantal, Morselli, Eugenia, Vacchelli, Erika, Bennetzen, Martin, Magnes, Christoph, Sinner, Frank, Pieber, Thomas, López-Otín, Carlos, Maiuri, Maria Chiara, Codogno, Patrice, Andersen, Jens S., Hill, Joseph A., Madeo, Frank, Kroemer, Guido

Source: In Molecular Cell 6 March 2014 53(5):710-725

Nucleocytosolic Depletion of the Energy Metabolite Acetyl-Coenzyme A Stimulates Autophagy and Prolongs Lifespan

Authors: Eisenberg, Tobias, Schroeder, Sabrina, Andryushkova, Aleksandra, Pendl, Tobias, Küttner, Victoria, Bhukel, Anuradha, Mariño, Guillermo, Pietrocola, Federico, Harger, Alexandra, Zimmermann, Andreas, Moustafa, Tarek, Sprenger, Adrian, Jany, Evelyne, Büttner, Sabrina, Carmona-Gutierrez, Didac, Ruckenstuhl, Christoph, Ring, Julia, Reichelt, Wieland, Schimmel, Katharina, Leeb, Tina, Moser, Claudia, Schatz, Stefanie, Kamolz, Lars-Peter, Magnes, Christoph, Sinner, Frank, Sedej, Simon, Fröhlich, Kai-Uwe, Juhasz, Gabor, Pieber, Thomas R., Dengjel, Jörn, Sigrist, Stephan J., Kroemer, Guido, Madeo, Frank

Source: In Cell Metabolism 4 March 2014 19(3):431-444

Cytoplasmic STAT3 Represses Autophagy by Inhibiting PKR Activity

Authors: Shen, Shensi, Niso-Santano, Mireia, Adjemian, Sandy, Takehara, Tetsuo, Malik, Shoaib Ahmad, Minoux, Hervé, Souquere, Sylvie, Mariño, Guillermo, Lachkar, Sylvie, Senovilla, Laura, Galluzzi, Lorenzo, Kepp, Oliver, Pierron, Gérard, Maiuri, Maria Chiara, Hikita, Hayato, Kroemer, Romano, Kroemer, Guido

Source: In Molecular Cell 14 December 2012 48(5):667-680

An Immunosurveillance Mechanism Controls Cancer Cell Ploidy

Authors: Senovilla, Laura, Vitale, Ilio, Martins, Isabelle, Tailler, Maximilien, Pailleret, Claire, Michaud, Mickaël, Galluzzi, Lorenzo, Adjemian, Sandy, Kepp, Oliver, Niso-Santano, Mireia, Shen, Shensi, Mariño, Guillermo, Criollo, Alfredo, Boilève, Alice, Job, Bastien, Ladoire, Sylvain, Ghiringhelli, François, Sistigu, Antonella, Yamazaki, Takahiro, Rello-Varona, Santiago, Locher, Clara, Poirier-Colame, Vichnou, Talbot, Monique, Valent, Alexander, Berardinelli, Francesco, Antoccia, Antonio, Ciccosanti, Fabiola, Fimia, Gian Maria, Piacentini, Mauro, Fueyo, Antonio, Messina, Nicole L., Li, Ming, Chan, Christopher J., Sigl, Verena, Pourcher, Guillaume, Ruckenstuhl, Christoph, Carmona-Gutierrez, Didac, Lazar, Vladimir, Penninger, Josef M., Madeo, Frank, López-Otín, Carlos, Smyth, Mark J., Zitvogel, Laurence, Castedo, Maria, Kroemer, Guido

Source: Science, 2012 Sep . 337(6102), 1678-1684.

Access URL: http://dx.doi.org/10.1126/science.1224922

Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function

Authors: Mariño, Guillermo, Ugalde, Alejandro P., Fernández, Álvaro F., Osorio, Fernando G., Fueyo, Antonio, Freije, José M. P., López-Otín, Carlos

Source: Proceedings of the National Academy of Sciences of the United States of America, 2010 Sep . 107(37), 16268-16273.

Access URL: https://www.jstor.org/stable/20779652

Proteomic Profiling of Adipose Tissue from Zmpste24−/− Mice, a Model of Lipodystrophy and Premature Aging, Reveals Major Changes in Mitochondrial Function and Vimentin Processing

Authors: Peinado, Juan R. ^{‡, ‖}, Quirós, Pedro M. ^§, Pulido, Marina R. ^‡, Mariño, Guillermo ^§, Martínez-Chantar, Maria L. ^¶, Vázquez-Martínez, Rafael ^‡, Freije, José M.P. ^§, López-Otín, Carlos ^§, Malagón, María M. ^‡

Source: In Molecular & Cellular Proteomics November 2011 10(11)

Autophagy for tissue homeostasis and neuroprotection

Authors: Mariño, Guillermo, Madeo, Frank, Kroemer, Guido

Source: In Current Opinion in Cell Biology April 2011 23(2):198-206

Autophagy in Ras-Induced Malignant Transformation: Fatal or Vital?

Authors: Mariño, Guillermo, Martins, Isabelle, Kroemer, Guido

Source: In Molecular Cell 2011 42(1):1-3