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Acute and Chronic Effects of Rifampin on Letermovir Suggest Transporter Inhibition and Induction Contribute to Letermovir Pharmacokinetics

Authors: Robbins, Jonathan A., Menzel, Karsten, Lassman, Michael, Zhao, Tian, Fancourt, Craig, Chu, Xiaoyan, Mostoller, Kate, Witter, Rose, Marceau West, Rachel, Stoch, S. Aubrey, McCrea, Jacqueline B., Iwamoto, Marian

Source: Clinical pharmacology & therapeutics. 111(3):664-675

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140390848.0x000001&indx=1&recIds=ETOCvdc_100140390848.0x000001

CAPITAL: Optimal subgroup identification via constrained policy tree search

Authors: Cai, Hengrui, Lu, Wenbin, Marceau West, Rachel, Mehrotra, Devan V., Huang, Lingkang

Source: Statistics in medicine. 41(21):4227-4244

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100159003744.0x000001&indx=1&recIds=ETOCvdc_100159003744.0x000001

Analysis of composite time-to-event endpoints in cardiovascular outcome trials.

Authors: Marceau West, Rachel, Golm, Gregory, Mehrotra, Devan V

Source: Clinical Trials; Oct2024, Vol. 21 Issue 5, p576-583, 8p

Subject Terms: MYOCARDIAL infarction risk factors, CARDIOVASCULAR disease related mortality, ANGINA pectoris, DATA analysis, MEDICAL care, CLINICAL trials, HOSPITAL care, TREATMENT effectiveness, ACUTE coronary syndrome, MYOCARDIAL revascularization, SIMULATION methods in education, STATISTICS, STROKE, CARDIOVASCULAR system, TIME, DISEASE risk factors

Survival analysis using a 5‐step stratified testing and amalgamation routine (5‐STAR) in randomized clinical trials

Authors: Mehrotra, Devan V., Marceau West, Rachel

Source: Statistics in medicine. 39(30):4724-4744

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111924043.0x000001&indx=1&recIds=ETOCvdc_100111924043.0x000001

Survival analysis using a 5‐step stratified testing and amalgamation routine (5‐STAR) in randomized clinical trials

Authors: Mehrotra, Devan V., Marceau West, Rachel

Source: Statistics in medicine. 40(19):4341-4343

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131558242.0x000001&indx=1&recIds=ETOCvdc_100131558242.0x000001

Identifying individual risk rare variants using protein structure guided local tests (POINT).

Authors: Marceau West, Rachel¹, Lu, Wenbin¹, Rotroff, Daniel M.², Kuenemann, Melaine A.³, Chang, Sheng-Mao⁴, Wu, Michael C.⁵, Wagner, Michael J.⁶, Buse, John B.⁷, Motsinger-Reif, Alison A.^1,3, Fourches, Denis^3,8, Tzeng, Jung-Ying^1,3,4,9 jytzeng@stat.ncsu.edu

Source: PLoS Computational Biology. 2/19/2019, Vol. 15 Issue 2, p1-24. 24p. 2 Diagrams, 4 Charts, 4 Graphs.

Subject Terms: *PROTEIN structure, *PROTEOMICS, *OPERATOR theory, *QUANTITATIVE research, *KERNEL functions, *BIOLOGICAL databases

Favezelimab (anti-LAG-3) Plus Pembrolizumab in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL): Cohort 3 of a Multicohort Open-Label Phase 1/2 Study

Authors: Santoro, Armando, Johnson, Nathalie A., Savage, Kerry J., Avigdor, Abraham, Bazargan, Ali, Borchmann, Peter, Gasiorowski, Robin, Gregory, Gareth P., Herishanu, Yair, Madan, Sumit, Minuk, Leonard, Musuraca, Gerardo, Marceau West, Rachel, Pillai, Pallavi, Marinello, Patricia, Zinzani, Pier Luigi

Source: In Blood 2 November 2023 142 Supplement 1:1725-1725

Favezelimab in Combination with Pembrolizumab in Patients with Anti-PD-1-Naive Relapsed or Refractory Classical Hodgkin Lymphoma: Updated Analysis of an Open-Label Phase 1/2 Study

Authors: Johnson, Nathalie A., Lavie, David, Borchmann, Peter, Gregory, Gareth P., Herrera, Alex F., Minuk, Leonard, Vucinic, Vladan, Armand, Philippe, Avigdor, Abraham, Gasiorowski, Robin, Herishanu, Yair, Keane, Colm, Kuruvilla, John, Marceau West, Rachel, Pillai, Pallavi, Marinello, Patricia, Timmerman, John

Source: In Blood 2 November 2023 142 Supplement 1:1693-1693

Favezelimab in Combination with Pembrolizumab in Patients with Heavily Pretreated Anti-PD-1-Refractory Classical Hodgkin Lymphoma: Updated Analysis of an Open-Label Phase 1/2 Study

Authors: Timmerman, John, Lavie, David, Johnson, Nathalie A., Avigdor, Abraham, Borchmann, Peter, Andreadis, Charalambos, Bazargan, Ali, Gregory, Gareth P., Keane, Colm, Tzoran, Inna, Vucinic, Vladan, Zinzani, Pier Luigi, Marceau West, Rachel, Pillai, Pallavi, Marinello, Patricia, Herrera, Alex F.

Source: In Blood 2 November 2023 142 Supplement 1:4440-4440

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Association test using Copy Number Profile Curves (CONCUR) enhances power in rare copy number variant analysis.

Authors: Brucker, Amanda, Lu, Wenbin, Marceau West, Rachel, Yu, Qi-You, Hsiao, Chuhsing Kate, Hsiao, Tzu-Hung, Lin, Ching-Heng, Magnusson, Patrik K. E., Sullivan, Patrick F., Szatkiewicz, Jin P., Lu, Tzu-Pin, Tzeng, Jung-Ying

Source: PLoS Computational Biology; 5/4/2020, Vol. 16 Issue 5, p1-23, 23p, 1 Diagram, 4 Charts, 4 Graphs

Subject Terms: DNA copy number variations, KERNEL functions, NEUROBEHAVIORAL disorders, TEST interpretation, CURVES

P1068: UPDATED RESULTS FROM AN OPEN-LABEL PHASE 1/2 STUDY OF FAVEZELIMAB IN COMBINATION WITH PEMBROLIZUMAB IN PATIENTS WITH RELAPSED OR REFRACTORY CLASSICAL HODGKIN LYMPHOMA AFTER ANTI–PD-1 TREATMENT.

Authors: Timmerman, John, Lavie, David, Johnson, Nathalie, Avigdor, Abraham, Borchmann, Peter, Andreadis, Charalambos, Bazargan, Ali, Gregory, Gareth, Keane, Colm, Tzoran, Inna, Vucinic, Vladan, Luigi Zinzani, Pier, Marceau West, Rachel, Pillai, Pallavi, Marinello, Patricia, Herrera, Alex F.

Source: HemaSphere; 2023 Supplement 3, Vol. 7, pe5990067-e5990067, 1p

P1065: UPDATED RESULTS FROM AN OPEN-LABEL PHASE 1/2 STUDY OF FAVEZELIMAB IN COMBINATION WITH PEMBROLIZUMAB IN PATIENTS WITH ANTI–PD-1–NAIVE RELAPSED OR REFRACTORY CLASSICAL HODGKIN LYMPHOMA.

Authors: Johnson, Nathalie, Lavie, David, Borchmann, Peter, Gregory, Gareth, Herrera, Alex F., Minuk, Leonard, Vucinic, Vladan, Armand, Philippe, Avigdor, Abraham, Gasiorowski, Robin, Herishanu, Yair, Keane, Colm, Kuruvilla, John, Marceau West, Rachel, Pillai, Pallavi, Marinello, Patricia, Timmerman, John

Source: HemaSphere; 2023 Supplement 3, Vol. 7, pe0274602-e0274602, 1p