ToTAL1y degraded - rapid dTAG proteolysis of TAL1 in T-cell acute lymphoblastic leukemia

Authors: Joana R. Costa, Marc R. Mansour

Source: Haematologica, Vol 109, Iss 5 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/11380; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/c925fb8be5374df896241d7c127e7a66

Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma

Authors: Stien De Coninck, Renate De Smedt, Beatrice Lintermans, Lindy Reunes, Hansen J. Kosasih, Alexandra Reekmans, Lauren M. Brown, Nadine Van Roy, Bruno Palhais, Juliette Roels, Malaika Van der Linden, Jo Van Dorpe, Panagiotis Ntziachristos, Frederik W. van Delft, Marc R. Mansour, Tim Pieters, Tim Lammens, Barbara De Moerloose, Charles E. de Bock, Steven Goossens, Pieter Van Vlierberghe

Source: Haematologica, Vol 109, Iss 5 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/11338; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/a08f66779ce943b3bf87b6b00741dfb3

The role of noncoding mutations in blood cancers

Authors: Sunniyat Rahman, Marc R. Mansour

Source: Disease Models & Mechanisms, Vol 12, Iss 11 (2019)

Subject Terms: enhancers and promoters, gene regulation, haematological malignancy, noncoding genome, Medicine, Pathology, RB1-214

File Description: electronic resource

Relation: http://dmm.biologists.org/content/12/11/dmm041988; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411

Access URL: https://doaj.org/article/9af9e13f04cf456eb26ff0fc73a3f761

Disruption of asxl1 results in myeloproliferative neoplasms in zebrafish

Authors: Evisa Gjini, Chang-Bin Jing, Ashley T. Nguyen, Deepak Reyon, Emma Gans, Michiel Kesarsing, Joshua Peterson, Olga Pozdnyakova, Scott J. Rodig, Marc R. Mansour, Keith Joung, A. Thomas Look

Source: Disease Models & Mechanisms, Vol 12, Iss 5 (2019)

Subject Terms: Apoptosis, Hematopoietic stem cells, Myeloproliferative neoplasms, Tet2, Genome editing, Medicine, Pathology, RB1-214

File Description: electronic resource

Relation: http://dmm.biologists.org/content/12/5/dmm035790; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411

Access URL: https://doaj.org/article/ee5630c8439a4a52a7085e238f64e4e8

Small genomic insertions form enhancers that misregulate oncogenes

Authors: Brian J. Abraham, Denes Hnisz, Abraham S. Weintraub, Nicholas Kwiatkowski, Charles H. Li, Zhaodong Li, Nina Weichert-Leahey, Sunniyat Rahman, Yu Liu, Julia Etchin, Benshang Li, Shuhong Shen, Tong Ihn Lee, Jinghui Zhang, A. Thomas Look, Marc R. Mansour, Richard A. Young

Source: Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/83aabc930e7b4c009b32aff780ab64f2

Intensive Chemotherapy Is Associated With Poor Overall Survival in Autoimmune Disease-associated Myeloid Malignancies

Authors: Simon E. Richardson, Duncan Brian, Victoria Grandage, Rachael Hough, Panagiotis Kottaridis, Marc R. Mansour, Elspeth M. Payne, Asim Khwaja

Source: HemaSphere, Vol 3, Iss 1 (2019)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/HS9.0000000000000164; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/7dbadbb6e16d43a69d79dce4016c47f0

Prognostic impact of the absence of biallelic deletion at the TRG locus for pediatric patients with T-cell acute lymphoblastic leukemia treated on the Medical Research Council UK Acute Lymphoblastic Leukemia 2003 trial

Authors: Nadine Farah, Amy A Kirkwood, Sunniyat Rahman, Theresa Leon, Sarah Jenkinson, Rosemary E. Gale, Katharine Patrick, Jeremy Hancock, Sujith Samarasinghe, David C. Linch, Anthony V Moorman, Nicholas Goulden, Ajay Vora, Marc R. Mansour

Source: Haematologica, Vol 103, Iss 7 (2018)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/8532; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/2fd597fa6b7a4851a807edf8f7f8b49a

Correction: Corrigendum: Small genomic insertions form enhancers that misregulate oncogenes

Authors: Brian J. Abraham, Denes Hnisz, Abraham S. Weintraub, Nicholas Kwiatkowski, Charles H. Li, Zhaodong Li, Nina Weichert-Leahey, Sunniyat Rahman, Yu Liu, Julia Etchin, Benshang Li, Shuhong Shen, Tong Ihn Lee, Jinghui Zhang, A. Thomas Look, Marc R. Mansour, Richard A. Young

Source: Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/a5144bbffd064084a1cb968c0fb0bb7e

A modular protein language modelling approach to immunogenicity prediction.

Authors: Hugh O'Brien, Max Salm, Laura T Morton, Maciej Szukszto, Felix O'Farrell, Charlotte Boulton, Laurence King, Supreet Kaur Bola, Pablo D Becker, Andrew Craig, Morten Nielsen, Yardena Samuels, Charles Swanton, Marc R Mansour, Sine Reker Hadrup, Sergio A Quezada

Source: PLoS Computational Biology, Vol 20, Iss 11, p e1012511 (2024)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

Access URL: https://doaj.org/article/d0648697accf4d3db851dc1ee5b36eb3

Therapeutic targeting of 'undruggable' MYC

Authors: Victor Llombart, Marc R Mansour

Source: EBioMedicine, Vol 75, Iss , Pp 103756- (2022)

Subject Terms: MYC, Therapeutic strategies, Cancer, Small-molecule inhibitors, MYC protein interactors, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396421005508; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/c718c7ed00ef4887a7436619da8de720

Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP-related domain

Authors: Shuning He, Marc R Mansour, Mark W Zimmerman, Dong Hyuk Ki, Hillary M Layden, Koshi Akahane, Evisa Gjini, Eric D de Groh, Antonio R Perez-Atayde, Shizhen Zhu, Jonathan A Epstein, A Thomas Look

Source: eLife, Vol 5 (2016)

Subject Terms: nf1, neuroblastoma, zebrafish, peripheral sympathetic nervous system, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/14713; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/5441f057e8b24f8894e688432b587875