Metastasis organotropism in colorectal cancer: advancing toward innovative therapies

Authors: Kai He, Zhihan Wang, Maochao Luo, Bowen Li, Ning Ding, Lei Li, Bo He, Han Wang, Jiangjun Cao, Canhua Huang, Jun Yang, Hai-Ning Chen

Source: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-23 (2023)

Subject Terms: CRC, Organotropism, Metabolic reprogramming, Immune system, Cancer cell-organ interactions, Targeted therapy, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/372c395c8634439fbd05f463d195fc98

HSPA8 Activates Wnt/β‐Catenin Signaling to Facilitate BRAF V600E Colorectal Cancer Progression by CMA‐Mediated CAV1 Degradation

Authors: Bowen Li, Hui Ming, Siyuan Qin, Li Zhou, Zhao Huang, Ping Jin, Liyuan Peng, Maochao Luo, Tingting Zhang, Kui Wang, Rui Liu, Yih‐Cherng Liou, Edouard C. Nice, Jingwen Jiang, Canhua Huang

Source: Advanced Science, Vol 11, Iss 3, Pp n/a-n/a (2024)

Subject Terms: BRAF V600E, drug resistance, epithelial–mesenchymal transition, heat shock 70 kDa protein 8, Wnt/β‐catenin, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/7db976251388417fb8d1a9aedac62dba

Targeting PSAT1 to mitigate metastasis in tumors with p53-72Pro variant

Authors: Jingwen Jiang, Hai-Ning Chen, Ping Jin, Li Zhou, Liyuan Peng, Zhao Huang, Siyuan Qin, Bowen Li, Hui Ming, Maochao Luo, Na Xie, Wei Gao, Edouard C. Nice, Qiang Yu, Canhua Huang

Source: Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-14 (2023)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/a063a38a90044b598f89e07c240a37cd

Oncofetal reprogramming in tumor development and progression: novel insights into cancer therapy

Authors: Jiangjun Cao, Zhe Zhang, Li Zhou, Maochao Luo, Lei Li, Bowen Li, Edouard C. Nice, Weifeng He, Shaojiang Zheng, Canhua Huang

Source: MedComm, Vol 4, Iss 6, Pp n/a-n/a (2023)

Subject Terms: cancer therapy, drug resistance, embryonic development, tumor development and progression, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2688-2663

Access URL: https://doaj.org/article/c122501db8aa4648bbe200960d25e642

Disrupting metformin adaptation of liver cancer cells by targeting the TOMM34/ATP5B axis

Authors: Ping Jin, Jingwen Jiang, Li Zhou, Zhao Huang, Siyuan Qin, Hai‐Ning Chen, Liyuan Peng, Zhe Zhang, Bowen Li, Maochao Luo, Tingting Zhang, Hui Ming, Ning Ding, Lei Li, Na Xie, Wei Gao, Wei Zhang, Edouard C Nice, Yuquan Wei, Canhua Huang

Source: EMBO Molecular Medicine, Vol 14, Iss 12, Pp 1-19 (2022)

Subject Terms: hepatocellular carcinoma, metastasis, metformin adaptation, oxidative phosphorylation, TOMM34, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/21de7353346a45f899760eb85b44cfa8

Hypoxia-induced lncRNA STEAP3-AS1 activates Wnt/β-catenin signaling to promote colorectal cancer progression by preventing m6A-mediated degradation of STEAP3 mRNA

Authors: Li Zhou, Jingwen Jiang, Zhao Huang, Ping Jin, Liyuan Peng, Maochao Luo, Zhe Zhang, Yan Chen, Na Xie, Wei Gao, Edouard C. Nice, Jing-Quan Li, Hai-Ning Chen, Canhua Huang

Source: Molecular Cancer, Vol 21, Iss 1, Pp 1-22 (2022)

Subject Terms: Hypoxia, LncRNA STEAPS-AS1, STEAP3, m6A modification, YTHDF2, Wnt/β-catenin, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1476-4598

Access URL: https://doaj.org/article/44281bdaed5b4e568a7195b302e3f17b

Repurposing econazole as a pharmacological autophagy inhibitor to treat pancreatic ductal adenocarcinoma

Authors: Ningna Weng, Siyuan Qin, Jiayang Liu, Xing Huang, Jingwen Jiang, Li Zhou, Zhe Zhang, Na Xie, Kui Wang, Ping Jin, Maochao Luo, Liyuan Peng, Edouard C. Nice, Ajay Goel, Suxia Han, Canhua Huang, Qing Zhu

Source: Acta Pharmaceutica Sinica B, Vol 12, Iss 7, Pp 3085-3102 (2022)

Subject Terms: Econazole, Autophagy, PDAC, ATF3, AKT, Organoid, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S221138352200048X; https://doaj.org/toc/2211-3835

Access URL: https://doaj.org/article/c8ba57758bb54987a6c388a8f7bf5de5

PHLDB2 Mediates Cetuximab Resistance via Interacting With EGFR in Latent Metastasis of Colorectal CancerSummary

Authors: Maochao Luo, Zhao Huang, Xingyue Yang, Yan Chen, Jingwen Jiang, Lu Zhang, Li Zhou, Siyuan Qin, Ping Jin, Shuyue Fu, Liyuan Peng, Bowen Li, Yongting Fang, Wenchen Pu, Yanqiu Gong, Yu Liu, Zhixiang Ren, Qiu-Luo Liu, Cun Wang, Fangqiong Xiao, Du He, Hongying Zhang, Changlong Li, Heng Xu, Lunzhi Dai, Yong Peng, Zong-Gung Zhou, Canhua Huang, Hai-Ning Chen

Source: Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 4, Pp 1223-1242 (2022)

Subject Terms: EGFR, Latent Metastasis, Cetuximab Resistance, PHLDB2, Colorectal Cancer, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X21002617; https://doaj.org/toc/2352-345X

Access URL: https://doaj.org/article/a1daa589f2864ead9925abd441059ce7

Overcoming therapeutic resistance to platinum-based drugs by targeting Epithelial–Mesenchymal transition

Authors: Xirui Duan, Maochao Luo, Jian Li, Zhisen Shen, Ke Xie

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: platinum-based drugs, epithelial-mesenchymal transition, drug resistance, targeted therapy, cancer stem cells, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.1008027/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/5158743c34b046ebb99efa5f10f65c7e

Redox signaling at the crossroads of human health and disease

Authors: Jing Zuo, Zhe Zhang, Maochao Luo, Li Zhou, Edouard C. Nice, Wei Zhang, Chuang Wang, Canhua Huang

Source: MedComm, Vol 3, Iss 2, Pp n/a-n/a (2022)

Subject Terms: hydrogen peroxide, oxidative stress, reactive oxygen species, redox‐relevant disease, redox signaling, redox therapy, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2688-2663

Access URL: https://doaj.org/article/3412bee910374e9d8c5fe230ccd37f44

Exploiting Polyphenol-Mediated Redox Reorientation in Cancer Therapy

Authors: Lei Li, Ping Jin, Yueyue Guan, Maochao Luo, Yu Wang, Bo He, Bowen Li, Kai He, Jiangjun Cao, Canhua Huang, Jingquan Li, Zhisen Shen

Source: Pharmaceuticals, Vol 15, Iss 12, p 1540 (2022)

Subject Terms: polyphenol, oxidative stress, ROS, cancer therapy, drug delivery, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/15/12/1540; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/6bba4e05ae504e989c8c2f0a05e5257d

Epigenetic Regulation of Epithelial to Mesenchymal Transition in the Cancer Metastatic Cascade: Implications for Cancer Therapy

Authors: Qiu-Luo Liu, Maochao Luo, Canhua Huang, Hai-Ning Chen, Zong-Guang Zhou

Source: Frontiers in Oncology, Vol 11 (2021)

Subject Terms: epithelial to mesenchymal transition, epithelial–mesenchymal plasticity, epigenetics, metastatic cascade, cancer therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2021.657546/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/2f7bdcceb2564b9f830c339e8dbf5117

Antioxidant Therapy in Cancer: Rationale and Progress

Authors: Maochao Luo, Li Zhou, Zhao Huang, Bowen Li, Edouard C. Nice, Jia Xu, Canhua Huang

Source: Antioxidants, Vol 11, Iss 6, p 1128 (2022)

Subject Terms: reactive oxygen species, oxidative stress, antioxidants, cancer therapy, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/11/6/1128; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/1103a2fca1a94c209d775db820594906

Genomic evolution and diverse models of systemic metastases in colorectal cancer.

Authors: Hai-Ning Chen, Yang Shu, Fei Liao, Xue Liao, Hongying Zhang, Yun Qin, Zhu Wang, Maochao Luo, Qiuluo Liu, Zhinan Xue, Minyuan Cao, Shouyue Zhang, Wei-Han Zhang, Qianqian Hou, Xuyang Xia, Han Luo, Yan Zhang, Lie Yang, Jian-Kun Hu, Xianghui Fu

Source: Gut; Feb2022, Vol. 71 Issue 2, p322-332, 54p

Subject Terms: METASTASIS, COLORECTAL cancer, RECTAL cancer, PORTAL hypertension, COLORECTAL liver metastasis, LYMPHATIC metastasis

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