N-cadherin crosstalk with integrin weakens the molecular clutch in response to surface viscosity

Authors: Eva Barcelona-Estaje, Mariana A. G. Oliva, Finlay Cunniffe, Aleixandre Rodrigo-Navarro, Paul Genever, Matthew J. Dalby, Pere Roca-Cusachs, Marco Cantini, Manuel Salmeron-Sanchez

Source: Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/a543dfe5735e4aea80fa0fbcd864f61a

Considerations of growth factor and material use in bone tissue engineering using biodegradable scaffolds in vitro and in vivo

Authors: Karen M. Marshall, Jonathan P. Wojciechowski, Vineetha Jayawarna, Abshar Hasan, Cécile Echalier, Øystein Øvrebø, Tao Yang, Kun Zhou, Janos M. Kanczler, Alvaro Mata, Manuel Salmeron-Sanchez, Molly M. Stevens, Richard O. C. Oreffo

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)

Subject Terms: Bioactive coating, Biomaterial, Bone tissue engineering, CAM assay, Animal models, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/0d419b7d66ce40a3b41f8cab151ffb49

Bioactive Coatings on 3D Printed Polycaprolactone Scaffolds for Bone Regeneration: A Novel Murine Femur Defect Model for Examination of the Biomaterial Capacity for Repair

Authors: Karen M. Marshall, Jonathan P. Wojciechowski, Vineetha Jayawarna, Abshar Hasan, Cécile Echalier, Sebastien J. P. Callens, Tao Yang, Janos M. Kanczler, Jonathan I. Dawson, Alvaro Mata, Manuel Salmeron‐Sanchez, Molly M. Stevens, Richard O. C. Oreffo

Source: Advanced Materials Interfaces, Vol 12, Iss 1, Pp n/a-n/a (2025)

Subject Terms: bioactive, biomaterial, bone tissue engineering, femur defect model, Laponite, Physics, QC1-999, Technology

File Description: electronic resource

Relation: https://doaj.org/toc/2196-7350

Access URL: https://doaj.org/article/09d6783ba46144f9b06408f6b6db0002

Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells

Authors: Hannah Donnelly, Ewan Ross, Yinbo Xiao, Rio Hermantara, Aqeel F. Taqi, W. Sebastian Doherty-Boyd, Jennifer Cassels, Penelope. M. Tsimbouri, Karen M. Dunn, Jodie Hay, Annie Cheng, R. M. Dominic Meek, Nikhil Jain, Christopher West, Helen Wheadon, Alison M. Michie, Bruno Peault, Adam G. West, Manuel Salmeron-Sanchez, Matthew J. Dalby

Source: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/e8984c0b474a49c1b8fa3b60f306f23a

Collagen IV deficiency causes hypertrophic remodeling and endothelium-dependent hyperpolarization in small vessel disease with intracerebral hemorrhageResearch in context

Authors: Sarah McNeilly, Cameron R. Thomson, Laura Gonzalez-Trueba, Yuan Yan Sin, Alessandra Granata, Graham Hamilton, Michelle Lee, Erin Boland, John D. McClure, Cristina Lumbreras-Perales, Alisha Aman, Apoorva A. Kumar, Marco Cantini, Caglar Gök, Delyth Graham, Yasuko Tomono, Christopher D. Anderson, Yinhui Lu, Colin Smith, Hugh S. Markus, Marc Abramowicz, Catheline Vilain, Rustam Al-Shahi Salman, Manuel Salmeron-Sanchez, Atticus H. Hainsworth, William Fuller, Karl E. Kadler, Neil J. Bulleid, Tom Van Agtmael

Source: EBioMedicine, Vol 107, Iss , Pp 105315- (2024)

Subject Terms: Collagen, Basement membrane, Cerebrovascular disease, Stroke, Small vessel disease, Endothelial dysfunction, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396424003517; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/d38bd2e3219f479e9d1e302cbcbad3f9

An engineered periosteum for efficient delivery of rhBMP-2 and mesenchymal progenitor cells during bone regeneration

Authors: Juan Antonio Romero-Torrecilla, José María Lamo-Espinosa, Purificación Ripalda-Cemboráin, Tania López-Martínez, Gloria Abizanda, Luis Riera-Álvarez, Sergio Ruiz de Galarreta-Moriones, Asier López-Barberena, Naiara Rodríguez-Flórez, Reyes Elizalde, Vineetha Jayawarna, José Valdés-Fernández, Miguel Echanove-González de Anleo, Peter Childs, Elena de Juan-Pardo, Manuel Salmeron-Sanchez, Felipe Prósper, Emma Muiños-López, Froilán Granero-Moltó

Source: npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-14 (2023)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2057-3995

Access URL: https://doaj.org/article/15f53af8ed3f4d18972df1164fd33675

Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells

Authors: Ewan A. Ross, Lesley-Anne Turner, Hannah Donnelly, Anwer Saeed, Monica P. Tsimbouri, Karl V. Burgess, Gavin Blackburn, Vineetha Jayawarna, Yinbo Xiao, Mariana A. G. Oliva, Jennifer Willis, Jaspreet Bansal, Paul Reynolds, Julia A. Wells, Joanne Mountford, Massimo Vassalli, Nikolaj Gadegaard, Richard O. C. Oreffo, Manuel Salmeron-Sanchez, Matthew J. Dalby

Source: Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/3492f3b33d7a422a8a602e5982a536a0

The influence of nanotopography on cell behaviour through interactions with the extracellular matrix – A review

Authors: Jiajun Luo, Matthew Walker, Yinbo Xiao, Hannah Donnelly, Matthew J. Dalby, Manuel Salmeron-Sanchez

Source: Bioactive Materials, Vol 15, Iss , Pp 145-159 (2022)

Subject Terms: Nanotopography, Cell-material interaction, Protein adsorption, Biomaterials, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452199X21005521; https://doaj.org/toc/2452-199X

Access URL: https://doaj.org/article/064485857dd643b58bb878352a1473a5

Protease-degradable hydrogels with multifunctional biomimetic peptides for bone tissue engineering

Authors: Lluís Oliver-Cervelló, Helena Martin-Gómez, Cristina Gonzalez-Garcia, Manuel Salmeron-Sanchez, Maria-Pau Ginebra, Carlos Mas-Moruno

Source: Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)

Subject Terms: biomimetic peptides, DWIVA, hydrogel, functionalization, osteogenic differentiation, multifunctionality, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fbioe.2023.1192436/full; https://doaj.org/toc/2296-4185

Access URL: https://doaj.org/article/d6a14c7596e64f6da6620e5158f31941

Engineered dual affinity protein fragments to bind collagen and capture growth factors

Authors: Stylianos O. Sarrigiannidis, Oana Dobre, Alexandre Rodrigo Navarro, Matthew J. Dalby, Cristina Gonzalez-Garcia, Manuel Salmeron-Sanchez

Source: Materials Today Bio, Vol 20, Iss , Pp 100641- (2023)

Subject Terms: Collagen, Bone regeneration, Recombinant protein fragment, Fibronectin, Biomaterials, Human mesenchymal stem cells, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590006423001011; https://doaj.org/toc/2590-0064

Access URL: https://doaj.org/article/59d2b39d7f7642888f3ee3b353a54bf9

Material-driven fibronectin and vitronectin assembly enhances BMP-2 presentation and osteogenesis

Authors: Yinbo Xiao, Hannah Donnelly, Mark Sprott, Jiajun Luo, Vineetha Jayawarna, Leandro Lemgruber, P. Monica Tsimbouri, R.M. Dominic Meek, Manuel Salmeron-Sanchez, Matthew J. Dalby

Source: Materials Today Bio, Vol 16, Iss , Pp 100367- (2022)

Subject Terms: Mesenchymal stem cells, Polymer organized extracellular matrix, Vitronectin, Fibronectin, Bone morphogenetic protein-2, Osteogenesis, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S259000642200165X; https://doaj.org/toc/2590-0064

Access URL: https://doaj.org/article/5d45369214394666b42781f7ad3ce560

Vitronectin-based hydrogels recapitulate neuroblastoma growth conditions

Authors: Ezequiel Monferrer, Oana Dobre, Sara Trujillo, Mariana Azevedo González Oliva, Alexandre Trubert-Paneli, Delia Acevedo-León, Rosa Noguera, Manuel Salmeron-Sanchez

Source: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

Subject Terms: vitronectin, neuroblastoma, polyethylene-glycol, stiffness, extracellular matrix, digital image analysis, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2022.988699/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/316a2c81576d4da5bddd27d6d40e297e

Biochemical‐ and Biophysical‐Induced Barriergenesis in the Blood–Brain Barrier: A Review of Barriergenic Factors for Use in In Vitro Models

Authors: Christina L. Schofield, Aleixandre Rodrigo-Navarro, Matthew J. Dalby, Tom Van Agtmael, Manuel Salmeron-Sanchez

Source: Advanced NanoBiomed Research, Vol 1, Iss 5, Pp n/a-n/a (2021)

Subject Terms: blood–brain barrier, endothelial cells, flows, growth factors, mechanics, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/2699-9307

Access URL: https://doaj.org/article/ddfb8e252e254d8488e30243024dc8c9

Zinc Maintains Embryonic Stem Cell Pluripotency and Multilineage Differentiation Potential via AKT Activation

Authors: Hayk Mnatsakanyan, Roser Sabater i Serra, Manuel Salmeron-Sanchez, Patricia Rico

Source: Frontiers in Cell and Developmental Biology, Vol 7 (2019)

Subject Terms: zinc, ZIP7, stemness maintenance, embryonic stem cells (ESC), AKT, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fcell.2019.00180/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/5a2a50e0c72e4d599a234ddc3a95a293

3D gelatin-chitosan hybrid hydrogels combined with human platelet lysate highly support human mesenchymal stem cell proliferation and osteogenic differentiation

Authors: Federica Re, Luciana Sartore, Vladimira Moulisova, Marco Cantini, Camillo Almici, Andrea Bianchetti, Clizia Chinello, Kamol Dey, Silvia Agnelli, Cristina Manferdini, Simona Bernardi, Nicola F. Lopomo, Emilio Sardini, Elisa Borsani, Luigi F. Rodella, Fabio Savoldi, Corrado Paganelli, Pierangelo Guizzi, Gina Lisignoli, Fulvio Magni, Manuel Salmeron-Sanchez, Domenico Russo

Source: Journal of Tissue Engineering, Vol 10 (2019)

Subject Terms: Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/2041-7314

Access URL: https://doaj.org/article/ff1215f4f3684bd785550a296acd08e8

Impact of surface topography and coating on osteogenesis and bacterial attachment on titanium implants

Authors: Laila Damiati, Marcus G Eales, Angela H Nobbs, Bo Su, Penelope M Tsimbouri, Manuel Salmeron-Sanchez, Matthew J Dalby

Source: Journal of Tissue Engineering, Vol 9 (2018)

Subject Terms: Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/2041-7314

Access URL: https://doaj.org/article/a5a64507a5ce4787a78e11a928dbf4cb

A fractal nature for polymerized laminin.

Authors: Camila Hochman-Mendez, Marco Cantini, David Moratal, Manuel Salmeron-Sanchez, Tatiana Coelho-Sampaio

Source: PLoS ONE, Vol 9, Iss 10, p e109388 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/b4731583d9ba42b18149dfbdacade051

Experimental and Data Analysis Workflow for Soft Matter Nanoindentation

Authors: Giuseppe Ciccone, author¹, Mariana Azevedo Gonzalez Oliva, author¹, Nelda Antonovaite, author², Ines Lüchtefeld, author³, Manuel Salmeron-Sanchez, author¹, Massimo Vassalli, author¹

Source: Journal of Visualized Experiments. (179)

Availability: http://www.jove.com/video/63401

Sustained adenosine release: Revealing its impact on osteogenic signalling pathways of human mesenchymal stromal cells

Authors: Hadi Hajiali, Jane McLaren, Cristina Gonzalez-García, Salah Abdelrazig, Dong-Hyun Kim, Matthew J. Dalby, Manuel Salmerón-Sánchez, Felicity R.A.J. Rose

Source: Engineered Regeneration, Vol 5, Iss 2, Pp 255-268 (2024)

Subject Terms: Adenosine release, Osteogenic signalling pathways, Human mesenchymal stromal cells, Bone regeneration, Life, QH501-531

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666138124000197; https://doaj.org/toc/2666-1381

Access URL: https://doaj.org/article/6adc2cebbe1349f39c6015cbe6e5f738

Tissue engineered scaffolds for mimetic autografts

Authors: Juan Antonio Romero-Torrecilla, Luis Riera, José Valdés-Fernández, Tania López-Martínez, Purificación Ripalda-Cemboráin, Vineetha Jayawarna, Peter Childs, Manuel Salmerón-Sánchez, Felipe Prósper-Cardoso, Froilán Granero-Moltó

Source: Bone Reports, Vol 13, Iss , Pp 100386- (2020)

Subject Terms: Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352187220301467; https://doaj.org/toc/2352-1872

Access URL: https://doaj.org/article/15d6c3b14d3344d2bc6238f56a7e7d7f