Transcriptional repressor Capicua is a gatekeeper of cell-intrinsic interferon responses

Authors: Manivasagam, Senthamizharasi ¹, Han, Julianna ², Teghanemt, Athmane ³, Keen, Henry ⁴, Sownthirarajan, Boopathi ¹, Cheng, Boyang ¹, Singh, Abhiraj ¹, Lewis, Abigail ¹, Vogel, Olivia A. ^{1, 2}, Loganathan, Gayathri ¹, Huang, Lei ⁵, Panis, Maryline ⁶, Meyerholz, David K. ⁷, tenOever, Benjamin ⁶, Perez, Jasmine T. ², Manicassamy, Santhakumar ⁸, Issuree, Priya D. ^{3, ∗}, Manicassamy, Balaji ^{1, 9, ∗∗}

Source: In Cell Host & Microbe 9 April 2025 33(4):512-528

Refinement of imidazo[2,1-a]pyrimidines in pursuit of potential drug candidates against group 2 influenza A viruses

Authors: Argade, Malaika D. ^{a, b, 1}, Anirudhan, Varada ^{c, 1}, Bradley, Sean P. ^{a, b}, Tomorowicz, Łukasz ^{a, b}, Bott, Ryan ^c, Sownthirarajan, Boopathi ^d, Zielinski, Christian A. ^{a, b}, Sloan, John P. ^b, Nikolic, Dejan S. ^{a, b}, Gaisin, Arsen M. ^{a, b}, Moore, Terry W. ^{b, e}, Manicassamy, Balaji ^d, Peet, Norton P. ^f, Rong, Lijun ^{c, f, ⁎}, Gaisina, Irina N. ^{a, b, f, ⁎⁎}

Source: In European Journal of Medicinal Chemistry 5 August 2025 292

Algorithmic Bio-surveillance For Precise Spatio-temporal Prediction of Zoonotic Emergence

Authors: Dhanoa, Jaideep, Manicassamy, Balaji, Chattopadhyay, Ishanu

Subject Terms: Quantitative Biology - Populations and Evolution, Computer Science - Learning, Statistics - Machine Learning

Access URL: http://arxiv.org/abs/1801.07807

Mathematical analysis of a mouse experiment suggests little role for resource depletion in controlling influenza infection within host

Authors: Ahmed, Hasan, Moore, James, Manicassamy, Balaji, Garcia-Sastre, Adolfo, Handel, Andreas, Antia, Rustom

Subject Terms: Quantitative Biology - Cell Behavior, Quantitative Biology - Populations and Evolution

Access URL: http://arxiv.org/abs/1705.02565

Generation of potent cellular and humoral immunity against SARS-CoV-2 antigens via conjugation to a polymeric glyco-adjuvant

Authors: Gray, Laura T., Raczy, Michal M., Briquez, Priscilla S., Marchell, Tiffany M., Alpar, Aaron T., Wallace, Rachel P., Volpatti, Lisa R., Sasso, Maria Stella, Cao, Shijie, Nguyen, Mindy, Mansurov, Aslan, Budina, Erica, Watkins, Elyse A., Solanki, Ani, Mitrousis, Nikolaos, Reda, Joseph W., Yu, Shann S., Tremain, Andrew C., Wang, Ruyi, Nicolaescu, Vlad, Furlong, Kevin, Dvorkin, Steve, Manicassamy, Balaji, Randall, Glenn, Wilson, D. Scott, Kwissa, Marcin, Swartz, Melody A., Hubbell, Jeffrey A.

Source: In Biomaterials November 2021 278

Identification of entry inhibitors with 4-aminopiperidine scaffold targeting group 1 influenza A virus

Authors: Hussein, Amira F.A., Cheng, Han, Tundup, Smanla, Antanasijevic, Aleksandar, Varhegyi, Elizabeth, Perez, Jasmine, AbdulRahman, Eiman M., Elenany, Mervat G., Helal, Soheir, Caffrey, Michael, Peet, Norton, Manicassamy, Balaji, Rong, Lijun

Source: In Antiviral Research May 2020 177

Genome-wide CRISPR/Cas9 Screen Identifies Host Factors Essential for Influenza Virus Replication

Authors: Han, Julianna, Perez, Jasmine T., Chen, Cindy, Li, Yan, Benitez, Asiel, Kandasamy, Matheswaran, Lee, Yoontae, Andrade, Jorge, tenOever, Benjamin, Manicassamy, Balaji

Source: In Cell Reports 10 April 2018 23(2):596-607

La Piedad Michoacán Mexico Virus V protein antagonizes type I interferon response by binding STAT2 protein and preventing STATs nuclear translocation

Authors: Pisanelli, Giuseppe, Laurent-Rolle, Maudry, Manicassamy, Balaji, Belicha-Villanueva, Alan, Morrison, Juliet, Lozano-Dubernard, Bernardo, Castro-Peralta, Felipa, Iovane, Giuseppe, García-Sastre., Adolfo

Source: In Virus Research 2 February 2016 213:11-22

A viral assembly inhibitor blocks SARS-CoV-2 replication in airway epithelial cells.

Authors: Du, Li, Deiter, Fred, Bouzidi, Mohamed S., Billaud, Jean-Noël, Simmons, Graham, Dabral, Prerna, Selvarajah, Suganya, Lingappa, Anuradha F., Michon, Maya, Yu, Shao Feng, Paulvannan, Kumar, Manicassamy, Balaji, Lingappa, Vishwanath R., Boushey, Homer, Greenland, John R., Pillai, Satish K.

Source: Communications Biology; 4/22/2024, Vol. 7 Issue 1, p1-14, 14p

Subject Terms: EPITHELIAL cells, SARS-CoV-2, TYPE I interferons, LIFE cycles (Biology), COVID-19 vaccines

Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding

Authors: Tripathi, Shashank, Pohl, Marie O., Zhou, Yingyao, Rodriguez-Frandsen, Ariel, Wang, Guojun, Stein, David A., Moulton, Hong M., DeJesus, Paul, Che, Jianwei, Mulder, Lubbertus C.F., Yángüez, Emilio, Andenmatten, Dario, Pache, Lars, Manicassamy, Balaji, Albrecht, Randy A., Gonzalez, Maria G., Nguyen, Quy, Brass, Abraham, Elledge, Stephen, White, Michael, Shapira, Sagi, Hacohen, Nir, Karlas, Alexander, Meyer, Thomas F., Shales, Michael, Gatorano, Andre, Johnson, Jeffrey R., Jang, Gwen, Johnson, Tasha, Verschueren, Erik, Sanders, Doug, Krogan, Nevan, Shaw, Megan, König, Renate, Stertz, Silke, García-Sastre, Adolfo, Chanda, Sumit K.

Source: In Cell Host & Microbe 9 December 2015 18(6):723-735

Expanding the tolerance of segmented Influenza A Virus genome using a balance compensation strategy.

Authors: Zhao, Xiujuan¹, Lin, Xiaojing², Li, Ping², Chen, Zinuo², Zhang, Chengcheng², Manicassamy, Balaji³, Rong, Lijun⁴, Lijun@uic.edu, Cui, Qinghua^1,5, Lijun@uic.edu, Du, Ruikun^1,5, Lijun@uic.edu

Source: PLoS Pathogens; 8/4/2022, Vol. 18 Issue 8, p1-21, 21p

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Engineered RNA viral synthesis of microRNAs

Authors: Varble, Andrew, Chua, Mark A., Perez, Jasmine T., Manicassamy, Balaji, García-Sastre, Adolfo, tenOever, Benjamin R., Maniatis, Tom

Source: Proceedings of the National Academy of Sciences of the United States of America, 2010 Jun . 107(25), 11519-11524.

Access URL: https://www.jstor.org/stable/20724100

Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus

Authors: Manicassamy, Balaji, Manicassamy, Santhakumar, Belicha-Villanueva, Alan, Pisanelli, Giuseppe, Pulendran, Bali, Garcia-Sastre, Adolfo, Ahmed, Rafi

Source: Proceedings of the National Academy of Sciences of the United States of America, 2010 Jun . 107(25), 11531-11536.

Access URL: https://www.jstor.org/stable/20724102

Recombinant influenza viruses and uses thereof

Rab11a mediates cell-cell spread and reassortment of influenza A virus genomes via tunneling nanotubes.

Authors: Ganti, Ketaki¹, ketaki.ganti@emory.edu, Han, Julianna², Manicassamy, Balaji³, Lowen, Anice C.^1,4, ketaki.ganti@emory.edu

Source: PLoS Pathogens; 9/2/2021, Vol. 17 Issue 9, p1-22, 22p

An enzymatic virus-like particle assay for sensitive detection of virus entry

Authors: Tscherne, Donna M., Manicassamy, Balaji, García-Sastre, Adolfo

Source: In Journal of Virological Methods 2010 163(2):336-343

Host factor Rab11a is critical for efficient assembly of influenza A virus genomic segments.

Authors: Han, Julianna¹, Ganti, Ketaki², Sali, Veeresh Kumar³, Twigg, Carly³, Zhang, Yifeng³, Manivasagam, Senthamizharasi³, Liang, Chieh-Yu³, Vogel, Olivia A.³, Huang, Iris¹, Emmanuel, Shanan N.¹, Plung, Jesse¹, Radoshevich, Lillianna³, Perez, Jasmine T.¹, Lowen, Anice C.², Manicassamy, Balaji³, balaji-manicassamy@uiowa.edu

Source: PLoS Pathogens; 5/10/2021, Vol. 17 Issue 5, p1-24, 24p

The p150 Isoform of ADAR1 Blocks Sustained RLR signaling and Apoptosis during Influenza Virus Infection.

Authors: Vogel, Olivia A.¹, Han, Julianna¹, Liang, Chieh-Yu², Manicassamy, Santhakumar³, Perez, Jasmine T.¹, Manicassamy, Balaji², balaji-manicassamy@uiowa.edu

Source: PLoS Pathogens; 9/8/2020, Vol. 16 Issue 9, p1-25, 25p

Characterization of Marburg virus glycoprotein in viral entry

Authors: Manicassamy, Balaji, Wang, Jizhen, Rumschlag, Emily, Tymen, Stéphanie, Volchkova, Valentina, Volchkov, Viktor, Rong, Lijun

Source: In Virology 2007 358(1):79-88