Effectiveness of preventive treatment among different age groups and Mycobacterium tuberculosis infection status: a systematic review and individual-participant data meta-analysis of contact tracing studies

Authors: Martinez, Leonardo, Seddon, James, Liu, Qiao, Acuna Villaorduna, Carlos, Bonnet, Maryline, Carvalho, Anna Cristina C., Chan, Pei-Chun, Hill, Philip C, Lopez-Varela, Elisa, Donkor, Simon, Graham, Stephen M., Villalba, Julian A., Grandjean, Louis, Zellweger, Jean-Pierre, Wang, Jann-Yuan, Verhagen, Lilly M, van Schalkwykn, Cari, van der Loeff, Maarten F Schim, Sloot, Rosa, Trieu, Lisa, Ahuja, Shama Desai, Yoshiyama, Takashi, Mazahir, Rufaida, Martinsonn, Neil A, Jones-López, Edward C., Altet, Neus, Kato, Seiya, Fang, Chi-Tai, Geis, Steffen, Hauri, Anja, Long, Richard, Dobler, Claudia C, Cayla, Joan A, Chakhaia, Tsira, Chen, Cheng, García-Basteiro, Alberto L., Triasih, Rina, Huang, Li-Min, Sharma, Surendra, Hannoun, Djohar, Malone, LaShaunda L., Ling, Du-Lin, Kritski, Afrânio, Stein, Catherine M., Malik, Amyn A, Augusto, Orvalho, Vashishtha, Richa, Boulahbal, Fadila, Boom, W. Henry, Shen, Ye, Hesseling, Anneke C, Horsburgh, C. Robert, Lange, Christoph, Mandalakas, Anna M., Seddon, James A, Horsburgh, C Robert ^*, Mandalakas, Anna M ^*

Source: In The Lancet Respiratory Medicine August 2024 12(8):633-641

Effectiveness of the primary Bacillus Calmette-Guérin vaccine against the risk of Mycobacterium tuberculosis infection and tuberculosis disease: a meta-analysis of individual participant data

Authors: Pelzer, Puck T ^{a, b, c, d, ∗}, Stuck, Logan ^{a, d, ∗}, Martinez, Leonardo ^{e, ∗}, Richards, Alexandra S ^c, Acuña-Villaorduña, Carlos ^f, Aronson, Naomi E ^g, Bonnet, Maryline ^h, Carvalho, Anna C ⁱ, Chan, Pei-Chun ^{j, k, l}, Huang, Li-Min ^l, Fang, Chi-Tai ^k, Churchyard, Gavin ^{m, n, o}, Corral-Londoño, Helena del ^p, Datta, Manjula ^q, Espinal, Marcos A ^s, Fielding, Katherine ^{c, t}, Fiore-Gartland, Andrew J ^u, Garcia-Basteiro, Alberto ^v, Hanekom, Willem ^w, Hatherill, Mark ^x, Hill, Phillip C ^y, Huerga, Helena ^z, Jones-López, Edward C ^aa, Kritski, Afranio ^r, Mandalakas, Anna M ^{bb, cc}, Mangtani, Punam ^{c, t}, Martins Netto, Eduardo ^{dd, ee, ff}, Mayanja, Harriet ^gg, Mazahir, Rufaida ^hh, Murray, Megan ⁱⁱ, Rangaka, Molebogeng ^jj, Scriba, Thomas ^kk, Singh, Jitendra ^ll, Singh, Sarman ^{mm, nn, oo, pp}, Stein, Catherine M ^qq, Vekemans, Johan ^rr, Verhagen, Lilly M ^{ss, tt, uu}, Villalba, Julian A ^{vv, ww}, Wajja, Anne ^xx, Watson, Basilea ^yy, White, Richard G ^c, Cobelens, Frank G J ^{a, d}

Source: In The Lancet Microbe February 2025 6(2)

A novel method for detecting Lipoarabinomannan in urine with the promise of meeting the WHO target product profile for the diagnosis of tuberculosis

Authors: Reimann, Maja ^{f, g, h}, Avsar, Korkut ⁱ, DiNardo, Andrew ^{j, k}, Goldmann, Torsten ^{l, m}, Günther, Gunar ^{n, o}, Hoelscher, Michael ^{p, q, r, s}, Ibraim, Elmira ^{t, u}, Kalsdorf, Barbara ^{h, f, g}, Kaufmann, Stefan H.E. ^{v, w, x}, Köhler, Niklas ^{f, g, h, y}, Mandalakas, Anna Maria ^{f, g, j}, Maurer, Florian P. ^{z, aa}, Müller, Marius ^{ab, ac}, Olaru, Ioana D. ^{ad, ae, af}, Popa, Cristina ^{t, u}, Rachow, Andrea ^{p, q}, Rolling, Thierry ^{ag, ah}, Salzer, Helmut J.F. ^{ad, ai, aj}, Carballo, Patricia Sanchez ^{f, g, h}, Schuhmann, Maren ^{ak, al}, Schaub, Dagmar ^g, Spinu, Victor ^{t, u}, Terhalle, Elena ^{ad, am}, Unnewehr, Markus ^{an, ao}, Zielinski, Nika ^{f, g, h}, Heyckendorf, Jan ^{f, ap, aq}, Lange, Christoph ^{f, g, h, j}, Budde, Katharina ^a, Meiwes, Lennard ^a

Source: In Tuberculosis May 2025 152

Performance of a stool-based quantitative PCR assay for the diagnosis of tuberculosis in adolescents and adults: a multinational, prospective diagnostic accuracy study

Authors: Kay, Alexander, Vasiliu, Anca, Carratala-Castro, Lucia, Mtafya, Bariki, Mendez Reyes, Jose Euberto, Maphalala, Nontobeko, Munguambe, Shilzia, Mulengwa, Durbbin, Ness, Tara, Saavedra, Belen, Bacha, Jason, Maphalala, Gugu, Mejia, Rojelio, Mtetwa, Godwin, Acacio, Sozinho, Manjate, Patricia, Mambuque, Edson, Shiba, Nosisa, Kota, Nokwanda, Ziyane, Mangaliso, Ntinginya, Nyanda Elias, Lange, Christoph, Kirchner, H Lester, DiNardo, Andrew R, Garcia-Basteiro, Alberto L, Mandalakas, Anna Maria

Source: In The Lancet Microbe May 2024 5(5):e433-e441

Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a 2023 TBnet/RESIST-TB consensus statement

Authors: Domínguez, José, Boeree, Martin J, Cambau, Emmanuelle, Chesov, Dumitru, Conradie, Francesca, Cox, Vivian, Dheda, Keertan, Dudnyk, Andrii, Farhat, Maha R, Gagneux, Sebastien, Grobusch, Martin P, Gröschel, Matthias I, Guglielmetti, Lorenzo, Kontsevaya, Irina, Lange, Berit, van Leth, Frank, Lienhardt, Christian, Mandalakas, Anna M, Maurer, Florian P, Merker, Matthias, Miotto, Paolo, Molina-Moya, Barbara, Morel, Florence, Niemann, Stefan, Veziris, Nicolas, Whitelaw, Andrew, Horsburgh, Charles R, Lange, Christoph

Source: Lancet infectious diseases. 23(4):e122-e137

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186605397.0x000001&indx=1&recIds=ETOCvdc_100186605397.0x000001

Pediatric Post-TB Lung Disease: Ready for Prime Time?

Authors: Masekela, Refiloe, Mandalakas, Anna Maria

Source: American journal of respiratory and critical care medicine. 207(8):975-977

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631883447&indx=1&recIds=ETOCRN631883447

100 years of Mycobacterium bovis bacille Calmette-Guérin

Authors: Lange, Christoph, Aaby, Peter, Behr, Marcel A, Donald, Peter R, Kaufmann, Stefan H E, Netea, Mihai G, Mandalakas, Anna M

Source: Lancet infectious diseases. 22(1):e2-e12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196371962.0x000001&indx=1&recIds=ETOCvdc_100196371962.0x000001

Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course: a systematic review and individual participant data meta-analysis

Authors: Martinez, Leonardo, Cords, Olivia, Liu, Qiao, Acuna-Villaorduna, Carlos, Bonnet, Maryline, Fox, Greg J, Carvalho, Anna Cristina C, Chan, Pei-Chun, Croda, Julio, Hill, Philip C, Lopez-Varela, Elisa, Donkor, Simon, Fielding, Katherine, Graham, Stephen M, Espinal, Marcos A, Kampmann, Beate, Reingold, Arthur, Huerga, Helena, Villalba, Julian A, Grandjean, Louis, Sotgiu, Giovanni, Egere, Uzochukwu, Singh, Sarman, Zhu, Limei, Lienhardt, Christian, Denholm, Justin T, Seddon, James A, Whalen, Christopher C, García-Basteiro, Alberto L, Triasih, Rina, Chen, Cheng, Singh, Jitendra, Huang, Li-Min, Sharma, Surendra, Hannoun, Djohar, del Corral, Helena, Mandalakas, Anna M, Malone, LaShaunda L, Ling, Du-Lin, Kritski, Afrânio, Stein, Catherine M, Vashishtha, Richa, Boulahbal, Fadila, Fang, Chi-Tai, Boom, W Henry, Netto, Eduardo Martins, Lemos, Antonio Carlos, Hesseling, Anneke C, Kay, Alexander, Jones-López, Edward C, Horsburgh, C Robert, Lange, Christoph, Andrews, Jason R

Source: Lancet.Global health. 10(9):e1307-e1316

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100169137389.0x000001&indx=1&recIds=ETOCvdc_100169137389.0x000001

CRISPR detection of circulating cell-free Mycobacterium tuberculosis DNA in adults and children, including children with HIV: a molecular diagnostics study

Authors: Huang, Zhen, LaCourse, Sylvia M, Kay, Alexander W, Stern, Joshua, Escudero, Jaclyn N, Youngquist, Brady M, Zheng, Wenshu, Vambe, Debrah, Dlamini, Muyalo, Mtetwa, Godwin, Cranmer, Lisa M, Njuguna, Irene, Wamalwa, Dalton C, Maleche-Obimbo, Elizabeth, Catanzaro, Donald G, Lyon, Christopher J, John-Stewart, Grace, DiNardo, Andrew, Mandalakas, Anna M, Ning, Bo, Hu, Tony Y ^*

Source: In The Lancet Microbe July 2022 3(7):e482-e492

Paediatric tuberculosis – new advances to close persistent gaps

Authors: Marais, Ben J., Verkuijl, Sabine, Casenghi, Martina, Triasih, Rina, Hesseling, Anneke C., Mandalakas, Anna M., Marcy, Olivier, Seddon, James A., Graham, Stephen M., Amanullah, Farhana

Source: In International Journal of Infectious Diseases December 2021 113 Supplement 1:S63-S67

Using starling murmuration as a model for creating a global health community of practice to advance equity in scholarship.

Authors: Nguyen, Diane^1,2,3, diane.nguyen@bcm.edu, Ssebunya, Rogers N.⁴, Hirani, Kajal⁵, Mandalakas, Anna¹, Benjamin, Jennifer^1,2,3, Ligon, B. Lee^1,3, Thammasitboon, Satid^1,3

Source: Medical Teacher; Apr2024, Vol. 46 Issue 4, p537-544, 8p

Tuberculosis endotypes to guide stratified host-directed therapy

Authors: DiNardo, Andrew R., Nishiguchi, Tomoki, Grimm, Sandra L., Schlesinger, Larry S., Graviss, Edward A., Cirillo, Jeffrey D., Coarfa, Cristian, Mandalakas, Anna M., Heyckendorf, Jan, Kaufmann, Stefan H.E., Lange, Christoph, Netea, Mihai G., Van Crevel, Reinout

Source: In Med 12 March 2021 2(3):217-232

Whispers in the Wind: Face Mask Sampling for Mycobacterium tuberculosis Detection in Children With Pulmonary Tuberculosis.

Authors: Meiwes, Lennard, Kontsevaya, Irina, Chesov, Dumitru, Kulciţkaia, Stela, Dreyer, Viola, Hillemann, Doris, Dlamini, Qiniso, Williams, Caroline, Barer, Michael, Brinkmann, Folke, Krüger, Renate, Thee, Stephanie, Kay, Alexander, Mandalakas, Anna Maria, Lange, Christoph

Source: Journal of Infectious Diseases; 12/15/2024, Vol. 230 Issue 6, p1510-1517, 8p

Subject Terms: MYCOBACTERIUM tuberculosis, TUBERCULOSIS, MEDICAL masks, POLYMERASE chain reaction, NUCLEOTIDE sequencing

TCA metabolism regulates DNA hypermethylation in LPS and Mycobacterium tuberculosis-induced immune tolerance.

Authors: Abhimanyu, Longlax, Santiago Carrero, Tomoki Nishiguchi, Ladki, Malik, Sheikh, Daanish, Martinez, Amera L., Mace, Emily M., Grimm, Sandra L., Caldwell, Thaleia, Varela, Alexandra Portillo, Sekhar, Rajagopal V., Mandalakas, Anna M., Mlotshwa, Mandla, Ginidza, Sibuse, Cirillo, Jeffrey D., Wallis, Robert S., Netea, Mihai G., van Crevel, Reinout, Coarfa, Cristian, DiNardo, Andrew R.

Source: Proceedings of the National Academy of Sciences of the United States of America; 10/8/2024, Vol. 121 Issue 41, p1-S6, 17p

Subject Terms: DNA methylation, MYCOBACTERIUM tuberculosis, IMMUNOLOGICAL tolerance, ISOCITRATE dehydrogenase, TRICARBOXYLIC acids

Pulse Oximetry Accuracy in Children with Dark Skin Tones: Relevance to Acute Lower Respiratory Infection Care in Low- and Middle-Income Countries.

Authors: Hooli, Shubhada, Colbourn, Tim, Shah, Manish I., Murray, Kristy, Mandalakas, Anna, McCollum, Eric D.

Source: American Journal of Tropical Medicine & Hygiene; Oct2024, Vol. 111 Issue 4, p736-739, 4p

Tuberculosis: First in Flight

Authors: Fennelly, Kevin P., Martinez, Leonardo, Mandalakas, Anna Maria

Source: American journal of respiratory and critical care medicine. 205(3):272-274

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN628595380&indx=1&recIds=ETOCRN628595380

Effectiveness of preventive treatment among different age groups and Mycobacterium tuberculosisinfection status: a systematic review and individual-participant data meta-analysis of contact tracing studies

Authors: Martinez, Leonardo, Seddon, James A, Horsburgh, C Robert, Lange, Christoph, Mandalakas, Anna M, Martinez, Leonardo, Seddon, James, Liu, Qiao, Acuna Villaorduna, Carlos, Bonnet, Maryline, Carvalho, Anna Cristina C., Chan, Pei-Chun, Hill, Philip C, Lopez-Varela, Elisa, Donkor, Simon, Graham, Stephen M., Villalba, Julian A., Grandjean, Louis, Zellweger, Jean-Pierre, Wang, Jann-Yuan, Verhagen, Lilly M, van Schalkwykn, Cari, van der Loeff, Maarten F Schim, Sloot, Rosa, Trieu, Lisa, Ahuja, Shama Desai, Yoshiyama, Takashi, Mazahir, Rufaida, Martinsonn, Neil A, Jones-López, Edward C., Altet, Neus, Kato, Seiya, Fang, Chi-Tai, Geis, Steffen, Hauri, Anja, Long, Richard, Dobler, Claudia C, Cayla, Joan A, Chakhaia, Tsira, Chen, Cheng, García-Basteiro, Alberto L., Triasih, Rina, Huang, Li-Min, Sharma, Surendra, Hannoun, Djohar, Malone, LaShaunda L., Ling, Du-Lin, Kritski, Afrânio, Stein, Catherine M., Malik, Amyn A, Augusto, Orvalho, Vashishtha, Richa, Boulahbal, Fadila, Boom, W. Henry, Shen, Ye, Hesseling, Anneke C, Horsburgh, C. Robert, Lange, Christoph, Mandalakas, Anna M.

Source: The Lancet Respiratory Medicine; August 2024, Vol. 12 Issue: 8 p633-641, 9p

Revisiting diagnostics: high priority tuberculosis diagnostic tests that fill an unmet need: what we need and what we do not need.

Authors: Lange, Christoph^1,2,3,4 (AUTHOR) clange@fz-borstel.de, Mandalakas, Anna Maria^1,2,4 (AUTHOR), Lillebaek, Troels^5,6 (AUTHOR), Chesov, Dumitru^1,2,7 (AUTHOR), Dheda, Keertan^8,9 (AUTHOR), Saluzzo, Francesca^10,11 (AUTHOR)

Source: Clinical Microbiology & Infection. Mar2025, Vol. 31 Issue 3, p312-314. 3p.

Subject Terms: *DIAGNOSIS methods, *TUBERCULOSIS

The risk of tuberculosis in children after close exposure: a systematic review and individual-participant meta-analysis

Authors: Acuna-Villaorduna, Carlos, Desai Ahuja, Shama, Altet, Neus, Augusto, Orvalho, Baliashvili, Davit, Basu, Sanjay, Becerra, Mercedes, Bonnet, Maryline, Henry Boom, W., Borgdorff, Martien, Boulahbal, Fadila, Carvalho, Anna Cristina C., Cayla, Joan A., Chakhaia, Tsira, Chan, Pei-Chun, Cohen, Ted, Croda, Julio, Datta, Sumona, del Corral, Helena, Denholm, Justin T., Dietze, Reynaldo, Dobler, Claudia C., Donkor, Simon, Egere, Uzochukwu, Ellner, Jerrold J., Espinal, Marcos, Evans, Carlton A., Fang, Chi-Tai, Fielding, Katherine, Fox, Greg J., García, Luis F., García-Basteiro, Alberto L., Geis, Steffen, Graham, Stephen M., Grandjean, Louis, Hannoun, Djohar, Hatherill, Mark, Hauri, Anja M., Hesseling, Anneke C., Hill, Philip C., Huang, Li-Min, Huerga, Helena, Hussain, Rabia, Jarlsberg, Leah, Jones-López, Edward C., Kato, Seiya, Kato-Maeda, Midori, Kampmann, Beate, Kirchner, H. Lester, Kritski, Afrânio, Lange, Christoph, Lee, Chih-Hsin, Lee, Li-Na, Lee, Meng-Rui, Lemos, Antonio Carlos, Lienhardt, Christian, Ling, Du-Lin, Liu, Qiao, Lo, Nathan C., Long, Richard, Lopez-Varela, Elisa, Lu, Peng, Magee, Matthew, Malone, LaShaunda L., Mandalakas, Anna M., Martinson, Neil A., Mazahir, Rufaida, Murray, Megan B., Netto, Eduardo Martins, Otero, Larissa, Parsonnet, Julie, Reingold, Arthur, Schaaf, H. Simon, Seddon, James A., Sharma, Surendra, Singh, Jitendra, Singh, Sarman, Sloot, Rosa, Sotgiu, Giovanni, Stein, Catherine M., Iqbal, Najeeha Talat, Triasih, Rina, Trieu, Lisa, van der Loeff, Maarten F Schim, Van der Stuyft, Patrick, van Schalkwyk, Cari, Vashishtha, Richa, Verhagen, Lilly M, Villalba, Julian A., Wang, Jann-Yuan, Whalen, Christopher C., Yoshiyama, Takashi, Zar, Heather J., Zellweger, Jean-Pierre, Zhu, Limei, Martinez, Leonardo ^*, Cords, Olivia, Horsburgh, C Robert, Andrews, Jason R

Source: In The Lancet 21-27 March 2020 395(10228):973-984

Quality matters: Redefining child TB care with an emphasis on quality

Authors: Amanullah, Farhana, Bacha, Jason Michael, Fernandez, Lucia Gonzalez, Mandalakas, Anna Maria

Source: In Journal of Clinical Tuberculosis and Other Mycobacterial Diseases December 2019 17