Performance of a stool-based quantitative PCR assay for the diagnosis of tuberculosis in adolescents and adults: a multinational, prospective diagnostic accuracy study

Authors: Kay, Alexander, Vasiliu, Anca, Carratala-Castro, Lucia, Mtafya, Bariki, Mendez Reyes, Jose Euberto, Maphalala, Nontobeko, Munguambe, Shilzia, Mulengwa, Durbbin, Ness, Tara, Saavedra, Belen, Bacha, Jason, Maphalala, Gugu, Mejia, Rojelio, Mtetwa, Godwin, Acacio, Sozinho, Manjate, Patricia, Mambuque, Edson, Shiba, Nosisa, Kota, Nokwanda, Ziyane, Mangaliso, Ntinginya, Nyanda Elias, Lange, Christoph, Kirchner, H Lester, DiNardo, Andrew R, Garcia-Basteiro, Alberto L, Mandalakas, Anna Maria

Source: In The Lancet Microbe May 2024 5(5):e433-e441

Monitoring of First-line Drug Resistance Mutations Outside the Scope of Xpert MTB/RIF Ultra is Needed for Successful Control of DR-TB in Southern Mozambique.

Authors: Mariner-Llicer, Carla, Cervera, Belén Saavedra, Mambuque, Edson, Gomes, Neide, Munguambe, Shilzia, Villamayor, Luis, Cancino-Muñoz, Irving, Torres-Puente, Manuela, Nguenha, Dinis, Respeito, Durval, Tembe, Gustavo, López, Mariana G, Comas, Iñaki, García-Basteiro, Alberto L

Source: Clinical Infectious Diseases; 4/15/2024, Vol. 78 Issue 4, p842-845, 4p

Subject Terms: GENOMICS, RESEARCH funding, MULTIDRUG resistance, DESCRIPTIVE statistics, ODDS ratio, GENETIC mutation, CONFIDENCE intervals, LATENT tuberculosis, MYCOBACTERIUM tuberculosis, MOLECULAR diagnosis, SEQUENCE analysis, SINGLE nucleotide polymorphisms, INFECTIOUS disease transmission

Geographic Terms: MOZAMBIQUE

Direct genotyping of Mycobacterium tuberculosis from Xpert® MTB/RIF remnants

Authors: Mambuque, Edson T., Abascal, Estefanía, Venter, Rouxjeane, Bulo, Helder, Bouza, Emilio, Theron, Grant, García-Basteiro, Alberto L., García-de-Viedma, Darío

Source: Tuberculosis. 111:202-206

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100084375402.0x000001&indx=1&recIds=ETOCvdc_100084375402.0x000001

A stool based qPCR for the diagnosis of TB in children and people living with HIV in Uganda, Eswatini and Mozambique (Stool4TB): a protocol for a multicenter diagnostic evaluation.

Authors: Carratala-Castro, Lucia, Ssengooba, Willy, Kay, Alex, Acácio, Sozinho, Ehrlich, Joanna, DiNardo, Andrew R, Shiba, Nosisa, Nsubuga, Joachim K, Munguambe, Shilzia, Saavedra-Cervera, Belén, Manjate, Patricia, Mulengwa, Durbbin, Sibandze, Busizwe, Ziyane, Mangaliso, Kasule, George, Mambuque, Edson, Sekadde, Moorine Penninah, Wobudeya, Eric, Joloba, Moses L, Heyckendorf, Jan

Source: BMC Infectious Diseases; 2/21/2024, Vol. 24 Issue 1, p1-9, 9p

Subject Terms: HIV-positive persons, TUBERCULOSIS, MYCOBACTERIUM tuberculosis, SYMPTOMS, URINARY tract infections, X-ray imaging, SPINAL tuberculosis

Geographic Terms: UGANDA, MOZAMBIQUE

Company/Entity: BAYLOR College of Medicine

Diagnostic performance of the Abbott RealTime MTB assay for tuberculosis diagnosis in people living with HIV.

Authors: Saavedra, Belén^1,2,3 (AUTHOR) belen.saavedra@manhica.net, Mambuque, Edson² (AUTHOR), Gomes, Neide² (AUTHOR), Nguenha, Dinis² (AUTHOR), Mabunda, Rita² (AUTHOR), Faife, Luis⁴ (AUTHOR), Langa, Ruben⁴ (AUTHOR), Munguambe, Shilzia² (AUTHOR), Manjate, Filomena² (AUTHOR), Cossa, Anelsio² (AUTHOR), Scott, Lesley⁵ (AUTHOR), García-Basteiro, Alberto L.^2,3 (AUTHOR)

Source: Scientific Reports. 9/29/2021, Vol. 11 Issue 1, p1-12. 12p.

Subject Terms: *TUBERCULOSIS, *HIV-positive persons, *MYCOBACTERIUM tuberculosis, *DIAGNOSIS

Geographic Terms: MOZAMBIQUE

Mortality and risk of tuberculosis among people living with HIV in whom TB was initially ruled out

Authors: García, Juan Ignacio, Mambuque, Edson, Nguenha, Dinis, Vilanculo, Faustino, Sacoor, Charfudin, Sequera, Victor Guillermo, Fernández-Quevedo, Manuel, Pierre, Maxime Leroux-La, Chiconela, Helio, Faife, Luis A., Respeito, Durval, Saavedra, Belén, Nhampossa, Tacilta, López-Varela, Elisa, Garcia-Basteiro, Alberto L.

Source: Scientific reports. 10(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174722505.0x000001&indx=1&recIds=ETOCvdc_100174722505.0x000001

Evaluation of Omnigene-Sputum for Preservation of Sputum Samples for Diagnosis of Mycobacterium tuberculosis.

Authors: Mambuque, Edson, Saavedra, Belén, Molina-Moya, Barbara, Nguenha, Dinis, García-García, Esther, Blanco, Silvia, Gomes, Neide, Ehrlich, Joanna, Bulo, Helder, Munguambe, Shilzia, Chiconela, Helio, Acacio, Sozinho, Domínguez, José, García-Basteiro, Alberto L.

Source: Tropical Medicine & Infectious Disease; Jul2023, Vol. 8 Issue 7, p367, 10p

Initiation and adherence to isoniazid preventive therapy in children under 5 years of age in Manhiça, Southern Mozambique.

Authors: Manuel-Rimbau, Agnès Montoya i de, Nguenha, Dinis, Mambuque, Edson, Ehrlich, Joanna, Munguambe, Shilzia, Saavedra, Belén, Matsena, Teodimiro, Chiconela, Hélio, Casellas, Aina, López-Varela, Elisa, Acacio, Sozinho, Garcia-Basteiro, Alberto L

Source: Journal of Tropical Pediatrics; Feb2023, Vol. 69 Issue 1, p1-4, 4p

Subject Terms: ISONIAZID, TUBERCULOSIS, PEDIATRIC therapy, MEDICAL centers

Geographic Terms: MOZAMBIQUE

Correlation of Xpert MTB/RIF with measures to assess Mycobacterium tuberculosis bacillary burden in high HIV burden areas of Southern Africa

Authors: Beynon, Fenella, Theron, Grant, Respeito, Durval, Mambuque, Edson, Saavedra, Belen, Bulo, Helder, Sanz, Sergi, Dheda, Keertan, Garcia-Basteiro, Alberto L.

Source: Scientific reports. 8(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131334953.0x000001&indx=1&recIds=ETOCvdc_100131334953.0x000001

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