Whole exome and transcriptome analysis revealed the activation of ERK and Akt signaling pathway in canine histiocytic sarcoma

Authors: Hajime Asada, Akiyoshi Tani, Hiroki Sakuma, Miyuki Hirabayashi, Yuki Matsumoto, Kei Watanabe, Masaya Tsuboi, Shino Yoshida, Kei Harada, Takao Uchikai, Yuko Goto-Koshino, James K. Chambers, Genki Ishihara, Tetsuya Kobayashi, Mitsuhiro Irie, Kazuyuki Uchida, Koichi Ohno, Makoto Bonkobara, Hajime Tsujimoto, Hirotaka Tomiyasu

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/af03d2782b0446e39e0c30681c9b4fd7

A feline case of multiple myeloma treated with bortezomib

Authors: Hiroyuki Tani, Ryo Miyamoto, Teruki Miyazaki, Shingo Oniki, Kyoichi Tamura, Makoto Bonkobara

Source: BMC Veterinary Research, Vol 18, Iss 1, Pp 1-6 (2022)

Subject Terms: Cat, Multiple myeloma, Bortezomib, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://doaj.org/toc/1746-6148

Access URL: https://doaj.org/article/31c85972294e46d6b3555035cc456e31

A canine case of malignant melanoma carrying a KIT c.1725_1733del mutation treated with toceranib: a case report and in vitro analysis

Authors: Hiroyuki Tani, Ryo Miyamoto, Syunya Noguchi, Sena Kurita, Tomokazu Nagashima, Masaki Michishita, Naoko Yayoshi, Kyoichi Tamura, Makoto Bonkobara

Source: BMC Veterinary Research, Vol 17, Iss 1, Pp 1-7 (2021)

Subject Terms: Dog, KIT, Toceranib, Malignant melanoma, Mutation, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://doaj.org/toc/1746-6148

Access URL: https://doaj.org/article/72bcb6d775514e2fb1f6c607fec8f79b

The secondary KIT mutation p.Ala510Val in a cutaneous mast cell tumour carrying the activating mutation p.Asn508Ile confers resistance to masitinib in dogs

Authors: Fabio Gentilini, Maria Elena Turba, Claire Dally, Masamine Takanosu, Sena Kurita, Makoto Bonkobara

Source: BMC Veterinary Research, Vol 16, Iss 1, Pp 1-9 (2020)

Subject Terms: Dogs, KIT, Mast cell tumours, Resistance, Somatic mutation, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12917-020-02284-9; https://doaj.org/toc/1746-6148

Access URL: https://doaj.org/article/815b68924e4c429eb522608cf5f4ff41

Canine REIC/Dkk-3 interacts with SGTA and restores androgen receptor signalling in androgen-independent prostate cancer cell lines

Authors: Yuiko Kato, Kazuhiko Ochiai, Shota Kawakami, Nobuhiro Nakao, Daigo Azakami, Makoto Bonkobara, Masaki Michishita, Masami Morimatsu, Masami Watanabe, Toshinori Omi

Source: BMC Veterinary Research, Vol 13, Iss 1, Pp 1-8 (2017)

Subject Terms: Androgen receptor (AR) signalling, Canine, Prostate cancer, Reduced expression in immortalised cells (REIC/Dkk-3), Small glutamine-rich tetratricopeptide repeat-containing protein α (SGTA), Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12917-017-1094-4; https://doaj.org/toc/1746-6148

Access URL: https://doaj.org/article/7bfc6b9ed9424551b996dc0b9dfa4eb8

Molecular Characterization of the Cytidine Monophosphate-N-Acetylneuraminic Acid Hydroxylase (CMAH) Gene Associated with the Feline AB Blood Group System.

Authors: Toshinori Omi, Shota Nakazawa, Chihiro Udagawa, Naomi Tada, Kazuhiko Ochiai, Yong Hwa Chong, Yuiko Kato, Hiroko Mitsui, Azusa Gin, Hitomi Oda, Daigo Azakami, Kyoichi Tamura, Toshinori Sako, Takeshi Inagaki, Atsushi Sakamoto, Toshihiko Tsutsui, Makoto Bonkobara, Shuichi Tsuchida, Shigenori Ikemoto

Source: PLoS ONE, Vol 11, Iss 10, p e0165000 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5068781?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/fcd0cb2d8b17401486850faf9bd9eb6f

A decrease in ubiquitination and resulting prolonged life-span of KIT underlies the KIT overexpression-mediated imatinib resistance of KIT mutation-driven canine mast cell tumor cells.

Authors: MASATO KOBAYASHI, SHIORI KUROKI, SENA KURITA, RYO MIYAMOTO, HIROYUKI TANI, KYOICHI TAMURA, MAKOTO BONKOBARA

Source: Oncology Reports; Oct2017, Vol. 38 Issue 4, p2543-2550, 8p, 4 Graphs

MicroRNA expression profiling in canine prostate cancer.

Authors: Masanori KOBAYASHI, Akiko SAITO, Yoshikazu TANAKA, Masaki MICHISHITA, Masato KOBAYASHI, Mami IRIMAJIRI, Takeharu KANEDA, Kazuhiko OCHIAI, Makoto BONKOBARA, Kimimasa TAKAHASHI, Tatsuya HORI, Eiichi KAWAKAMI

Source: Journal of Veterinary Medical Science; 2017, Vol. 79 Issue 4, p719-725, 7p

Subject Terms: PROSTATE cancer, MICRORNA, NON-coding RNA, EARLY diagnosis

Imatinib-associated tumour response in a dog with a non-resectable gastrointestinal stromal tumour harbouring a c-kit exon 11 deletion mutation.

Authors: Masato Kobayashi¹, Shiori Kuroki¹, Keita Ito¹, Akiko Yasuda², Harumi Sawada², Kenichiro Ono^1,3, Tsukimi Washizu¹, Makoto Bonkobara¹ bonkobara@nvlu.ac.jp

Source: Veterinary Journal. Oct2013, Vol. 198 Issue 1, p271-274. 4p.

Subject Terms: *MINIATURE dachshunds, *GASTROINTESTINAL stromal tumors, *IMATINIB, *NEOPLASTIC cell transformation, *EXONS (Genetics)

Identification of dasatinib as an in vitro potent growth inhibitor of canine histiocytic sarcoma cells.

Authors: Keita Ito¹, Shiori Kuroki¹, Masato Kobayashi¹, Kenichiro Ono^1,2, Tsukimi Washizu¹, Makoto Bonkobara¹ bonkobara@nvlu.ac.jp

Source: Veterinary Journal. Jun2013, Vol. 196 Issue 3, p538-540. 5p.

Subject Terms: *RETICULUM cell sarcoma, *CELL lines, *CHEMICAL libraries, *KINASES, *ENZYMES

Validation of the prognostic value of histopathological grading or c-kit mutation in canine cutaneous mast cell tumours: A retrospective cohort study.

Authors: Yoshinori Takeuchi^1,2, Yasuhito Fujino¹ afujino@mail.ecc.u-tokyo.ac.jp, Manabu Watanabe³, Masashi Takahashi⁴, Takayuki Nakagawa⁵, Ayano Takeuchi², Makoto Bonkobara⁶, Tetsuya Kobayashi⁷, Koichi Ohno¹, Kazuyuki Uchida⁸, Kazushi Asano⁹, Ryohei Nishimura⁴, Hiroyuki Nakayama⁸, Sumio Sugano³, Vasuo Ohashi², Hajime Tsujimoto¹

Source: Veterinary Journal. Jun2013, Vol. 196 Issue 3, p492-498. 7p.

Subject Terms: *MAST cells, *TUMORS, *NUCLEOTIDES, *NUCLEOTIDE sequence, *PATHOLOGY