Mechanism of ERBB2 gene overexpression by the formation of super-enhancer with genomic structural abnormalities in lung adenocarcinoma without clinically actionable genetic alterations

Authors: Syuzo Kaneko, Ken Takasawa, Ken Asada, Kouya Shiraishi, Noriko Ikawa, Hidenori Machino, Norio Shinkai, Maiko Matsuda, Mari Masuda, Shungo Adachi, Satoshi Takahashi, Kazuma Kobayashi, Nobuji Kouno, Amina Bolatkan, Masaaki Komatsu, Masayoshi Yamada, Mototaka Miyake, Hirokazu Watanabe, Akiko Tateishi, Takaaki Mizuno, Yu Okubo, Masami Mukai, Tatsuya Yoshida, Yukihiro Yoshida, Hidehito Horinouchi, Shun-Ichi Watanabe, Yuichiro Ohe, Yasushi Yatabe, Vassiliki Saloura, Takashi Kohno, Ryuji Hamamoto

Source: Molecular Cancer, Vol 23, Iss 1, Pp 1-17 (2024)

Subject Terms: Lung adenocarcinoma, Super-enhancers, Structural variations, Targeted therapy, Driver mutations, Integrated analysis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1476-4598

Access URL: https://doaj.org/article/41d2bbf4f86f4d019c77904a80b740d3

Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome‐wide association and whole genome sequencing analyses

Authors: Kouya Shiraishi, Atsushi Takahashi, Yukihide Momozawa, Yataro Daigo, Syuzo Kaneko, Takahisa Kawaguchi, Hideo Kunitoh, Shingo Matsumoto, Hidehito Horinouchi, Akiteru Goto, Takayuki Honda, Kimihiro Shimizu, Masahiro Torasawa, Daisuke Takayanagi, Motonobu Saito, Akira Saito, Yuichiro Ohe, Shun‐ichi Watanabe, Koichi Goto, Masahiro Tsuboi, Katsuya Tsuchihara, Sadaaki Takata, Tomomi Aoi, Atsushi Takano, Masashi Kobayashi, Yohei Miyagi, Kazumi Tanaka, Hiroyuki Suzuki, Daichi Maeda, Takumi Yamaura, Maiko Matsuda, Yoko Shimada, Takaaki Mizuno, Hiromi Sakamoto, Teruhiko Yoshida, Yasushi Goto, Tatsuya Yoshida, Taiki Yamaji, Makoto Sonobe, Shinichi Toyooka, Kazue Yoneda, Katsuhiro Masago, Fumihiro Tanaka, Megumi Hara, Nobuo Fuse, Satoshi S. Nishizuka, Noriko Motoi, Norie Sawada, Yuichiro Nishida, Kazuki Kumada, Kenji Takeuchi, Kozo Tanno, Yasushi Yatabe, Kuniko Sunami, Tomoyuki Hishida, Yasunari Miyazaki, Hidemi Ito, Mitsuhiro Amemiya, Hirohiko Totsuka, Haruhiko Nakayama, Tomoyuki Yokose, Kazuyoshi Ishigaki, Toshiteru Nagashima, Yoichi Ohtaki, Kazuhiro Imai, Ken Takasawa, Yoshihiro Minamiya, Kazuma Kobayashi, Kenichi Okubo, Kenji Wakai, Atsushi Shimizu, Masayuki Yamamoto, Motoki Iwasaki, Koichi Matsuda, Johji Inazawa, Yuichi Shiraishi, Hiroyoshi Nishikawa, Yoshinori Murakami, Michiaki Kubo, Fumihiko Matsuda, Yoichiro Kamatani, Ryuji Hamamoto, Keitaro Matsuo, Takashi Kohno

Source: Cancer Communications, Vol 44, Iss 2, Pp 287-293 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2523-3548

Access URL: https://doaj.org/article/a4b8ea6db19942899046a4b6375483b8

Rare FGFR fusion genes in cervical cancer and transcriptome‐based subgrouping of patients with a poor prognosis

Authors: Kengo Hiranuma, Yuka Asami, Mayumi Kobayashi Kato, Naoya Murakami, Yoko Shimada, Maiko Matsuda, Shu Yazaki, Erisa Fujii, Kazuki Sudo, Ikumi Kuno, Masaaki Komatsu, Ryuji Hamamoto, Hideki Makinoshima, Koji Matsumoto, Mitsuya Ishikawa, Takashi Kohno, Yasuhisa Terao, Atsuo Itakura, Hiroshi Yoshida, Kouya Shiraishi, Tomoyasu Kato

Source: Cancer Medicine, Vol 12, Iss 17, Pp 17835-17848 (2023)

Subject Terms: cervical cancer, fibroblast growth factor receptor 3, gene fusion, human papillomavirus, macrophage, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/16a7ff7c704942b4a949ca70b9e89c21

Comparison of clinicopathological and genomic profiles in anal squamous cell carcinoma between Japanese and Caucasian cohorts

Authors: Takahiko Ito, Daisuke Takayanagi, Shigeki Sekine, Taiki Hashimoto, Yoko Shimada, Maiko Matsuda, Masayoshi Yamada, Ryuji Hamamoto, Tomoyasu Kato, Dai Shida, Yukihide Kanemitsu, Narikazu Boku, Takashi Kohno, Atsuo Takashima, Kouya Shiraishi

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/5c62401519fd4daea4e73cec0c6d0bf9

Predictive model for the preoperative assessment and prognostic modeling of lymph node metastasis in endometrial cancer

Authors: Yuka Asami, Kengo Hiranuma, Daisuke Takayanagi, Maiko Matsuda, Yoko Shimada, Mayumi Kobayashi Kato, Ikumi Kuno, Naoya Murakami, Masaaki Komatsu, Ryuji Hamamoto, Takashi Kohno, Akihiko Sekizawa, Koji Matsumoto, Tomoyasu Kato, Hiroshi Yoshida, Kouya Shiraishi

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/65bcdc6953a2477681527a5dcc956d6e

TP53 mutants and non-HPV16/18 genotypes are poor prognostic factors for concurrent chemoradiotherapy in locally advanced cervical cancer

Authors: Ikumi Kuno, Daisuke Takayanagi, Yuka Asami, Naoya Murakami, Maiko Matsuda, Yoko Shimada, Sou Hirose, Mayumi Kobayashi Kato, Masaaki Komatsu, Ryuji Hamamoto, Kae Okuma, Takashi Kohno, Jun Itami, Hiroshi Yoshida, Kouya Shiraishi, Tomoyasu Kato

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/01be47dd8ca541d2a942cb3061a4dbb3

Distribution of genetic alterations in high-risk early-stage cervical cancer patients treated with postoperative radiation therapy

Authors: Naoya Murakami, Yuka Asami, Hiroshi Yoshida, Daisuke Takayanagi, Sou Hirose, Ikumi Kuno, Kazuaki Takahashi, Maiko Matsuda, Yoko Shimada, Shotaro Yamano, Kuniko Sunami, Takayuki Honda, Tomomi Nakahara, Tomoko Watanabe, Kae Okuma, Takafumi Kuroda, Takashi Kohno, Tomoyasu Kato, Kouya Shiraishi, Jun Itami

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/cda706406e7644d5a5156ae569f6d36b

A Pivotal Role for Pro-335 in Balancing the Dual Functions of Munc18-1 Domain-3a in Regulated Exocytosis.

Authors: Gayoung Anna Han^1,2, Seungmee Park^1,2, Na-Ryum Bin^1,2, Chang Hun Jung^1,2, Byungjin Kim¹, Prashanth Chandrasegaram¹, Maiko Matsuda¹, Indira Riadi¹, Liping Han^1,2, Shuzo Sugita^1,2 ssugita@uhnres.utoronto.ca

Source: Journal of Biological Chemistry. 11/28/2014, Vol. 289 Issue 48, p33617-33628. 12p.

Subject Terms: *EXOCYTOSIS, *PROTEIN research, *MOLECULAR chaperones, *SYNTAXINS, *CELL physiology