Effect of NK cell receptor genetic variation on allogeneic stem cell transplantation outcome and in vitro NK cell cytotoxicity

Authors: Julia Nihtilä, Leena Penna, Urpu Salmenniemi, Maija Itälä-Remes, Rachel E. Crossland, David Gallardo, Katarzyna Bogunia-Kubik, Piotr Lacina, Maria Bieniaszewska, Sebastian Giebel, Katariina Karjalainen, Farhana Jahan, Erja Kerkelä, Kati Hyvärinen, Satu Koskela, Jarmo Ritari, Jukka Partanen

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/ed68362eea4948b7ad4cd04484ae72b0

Treatment Patterns and Clinical Outcomes of Patients with Moderate to Severe Acute Graft-Versus-Host Disease: A Multicenter Chart Review Study

Authors: David Michonneau, Raynier Devillier, Mikko Keränen, Marie Thérèse Rubio, Malin Nicklasson, Hélène Labussière-Wallet, Martin Carre, Anne Huynh, Elisabet Viayna, Montserrat Roset, Jonathan Finzi, Minja Pfeiffer, Daniel Thunström, Núria Lara, Lorenzo Sabatelli, Patrice Chevallier, Maija Itälä-Remes

Source: Hematology Reports, Vol 16, Iss 2, Pp 283-294 (2024)

Subject Terms: hematopoietic stem cell transplantation, Europe, retrospective, mortality, real-world, Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://www.mdpi.com/2038-8330/16/2/28; https://doaj.org/toc/2038-8330

Access URL: https://doaj.org/article/c19848b2870645c89972a7581c0e60e1

CHEK2 GERMLINE VARIANTS AND ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANT OUTCOMES

Authors: Atte K Lahtinen, Jessica Koski, Jarmo Ritari, Kati Hyvärinen, Satu Koskela, Jukka Partanen, Kim Vettenranta, Minna Koskenvuo, Riitta Niittyvuopio, Urpu Salmenniemi, Maija Itälä-Remes, Kirsi Jahnukainen, Outi Kilpivaara, Ulla Wartiovaara- Kautto, Maarja Karu

Source: EJC Paediatric Oncology, Vol 2, Iss , Pp 100058- (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2772610X23000569; https://doaj.org/toc/2772-610X

Access URL: https://doaj.org/article/00460f5941584e5d97b84798c1738c14

P562: CAPILLARY BLOOD SAMPLING ALLOWS FEASIBLE METHOD FOR VENETOCLAX CONCENTRATION MEASUREMENT IN AN ACADEMIC MULTICENTER CLINICAL TRIAL CONTEXT

Authors: Sari Kytölä, Ida Vänttinen, Heikki Kuusanmäki, Tanja Ruokoranta, Mika Kurkela, Johanna Kiiski, Annasofia Holopainen, Anu Partanen, Milla E.L. Kuusisto, Sirpa Koskela, Riikka Räty, Maija Itälä-Remes, Pia Ettala, Johanna Rimpiläinen, Timo Siitonen, Marja Pyörälä, Janne T. Backman, Mikko Niemi, Mika Kontro

Source: HemaSphere, Vol 7, p e53119c1 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/01.HS9.0000969152.53119.c1; https://doaj.org/toc/2572-9241

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Significance of Degree of HLA Disparity Using T-cell Replete Peripheral Blood Stem Cells From Haploidentical Donors With Posttransplantation Cyclophosphamide in AML in First Complete Hematologic Remission: A Study of the Acute Leukemia Working Party of the EBMT

Authors: Mohamed A. Kharfan-Dabaja, Myriam Labopin, Ernesto Ayala, Ali Bazarbachi, Didier Blaise, Jan Vydra, Stefania Bramanti, Maija Itälä-Remes, Christoph Schmid, Alessandro Busca, Edouard Forcade, Werner Rabitsch, Marco Zecca, Nicolaus Kröger, Claude-Eric Bulabois, Giovanni Grillo, Alessandro Rambaldi, Renato Fanin, Francesco Zallio, Nicola Di Renzo, Yener Koc, Yana Novis, Andrew McDonald, Concepcion Herrera Arroyo, Jaime Sanz, Arnon Nagler, Fabio Ciceri, Mohamad Mohty

Source: HemaSphere, Vol 7, Iss 7, p e920 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/HS9.0000000000000920; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/a86fb26892d24374b8fde8eaa22d0625

Ex vivo venetoclax sensitivity testing predicts treatment response in acute myeloid leukemia

Authors: Heikki Kuusanmäki, Sari Kytölä, Ida Vänttinen, Tanja Ruokoranta, Amanda Ranta, Jani Huuhtanen, Minna Suvela, Alun Parsons, Annasofia Holopainen, Anu Partanen, Milla E.L. Kuusisto, Sirpa Koskela, Riikka Räty, Maija Itälä-Remes, Imre Västrik, Olli Dufva, Sanna Siitonen, Kimmo Porkka, Krister Wennerberg, Caroline A. Heckman, Pia Ettala, Marja Pyörälä, Johanna Rimpiläinen, Timo Siitonen, Mika Kontro

Source: Haematologica, Vol 108, Iss 7 (2022)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/10906; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/ed146fcdf2474b39baf1bf345a6c2b2c

Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease

Authors: Daehong Kim, Giljun Park, Jani Huuhtanen, Sofie Lundgren, Rajiv K. Khajuria, Ana M. Hurtado, Cecilia Muñoz-Calleja, Laura Cardeñoso, Valle Gómez-García de Soria, Tzu Hua Chen-Liang, Samuli Eldfors, Pekka Ellonen, Sari Hannula, Matti Kankainen, Oscar Bruck, Anna Kreutzman, Urpu Salmenniemi, Tapio Lönnberg, Andrés Jerez, Maija Itälä-Remes, Mikko Myllymäki, Mikko A. I. Keränen, Satu Mustjoki

Source: Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/ea0ed950dd9b43599b0f71b6f958e251

Copy number alterations define outcome in Philadelphia chromosome-positive acute lymphoblastic leukemia

Authors: Helena Hohtari, Niels Pallisgaard, Matti Kankainen, Pekka Ellonen, Oscar Brück, Timo Siitonen, Marjaana Säily, Marjatta Sinisalo, Marja Pyörälä, Maija Itälä-Remes, Perttu Koskenvesa, Erkki Elonen, Satu Mustjoki, Kimmo Porkka

Source: Haematologica, Vol 107, Iss 8 (2022)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/10625; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/5387630602a9470ab1aafc96dd4f32f5

Immunomonitoring of MSC-Treated GvHD Patients Reveals Only Moderate Potential for Response Prediction but Indicates Treatment Safety

Authors: Joni Keto, Tanja Kaartinen, Urpu Salmenniemi, Johanna Castrén, Jukka Partanen, Arno Hänninen, Matti Korhonen, Kaarina Lähteenmäki, Maija Itälä-Remes, Johanna Nystedt

Source: Molecular Therapy: Methods & Clinical Development, Vol 9, Iss , Pp 109-118 (2018)

Subject Terms: Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050118300135; https://doaj.org/toc/2329-0501

Access URL: https://doaj.org/article/10f41fb7114346d583caa5327b369bf7

Antibody persistence after pneumococcal conjugate vaccination in patients with chronic lymphocytic leukemia

Authors: Vesa Lindström, Janne Aittoniemi, Urpu Salmenniemi, Helena Käyhty, Heini Huhtala, Maija Itälä-Remes, Marjatta Sinisalo

Source: Human Vaccines & Immunotherapeutics, Vol 14, Iss 6, Pp 1471-1474 (2018)

Subject Terms: antibody persistence, chronic lymphocytic leukemia, pneumococcal conjugate vaccine, Immunologic diseases. Allergy, RC581-607, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2164-5515; https://doaj.org/toc/2164-554X

Access URL: https://doaj.org/article/be5d4bcbfddb4bd0a76dbdace697f96b

Post-transplant cyclophosphamide for graft-versus-host disease prophylaxis in HLA matched sibling or matched unrelated donor transplant for patients with acute leukemia, on behalf of ALWP-EBMT

Authors: Annalisa Ruggeri, Myriam Labopin, Andrea Bacigalupo, Boris Afanasyev, Jan J. Cornelissen, Ahmet Elmaagacli, Maija Itälä-Remes, Didier Blaise, Ellen Meijer, Yener Koc, Noel Milpied, Harry C. Schouten, Nicolaus Kroeger, Mohamad Mohty, Arnon Nagler

Source: Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-10 (2018)

Subject Terms: Hematopoietic stem cell transplantation, Post-transplantation cyclophosphamide, Stem cell source, Acute leukemia, Acute graft-versus-host disease, Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13045-018-0586-4; https://doaj.org/toc/1756-8722

Access URL: https://doaj.org/article/2d1c8d7b81804ce4b88caa3dea2f1dc3

Meta-Analysis of Genome-Wide Association and Gene Expression Studies Implicates Donor T Cell Function and Cytokine Pathways in Acute GvHD

Authors: Kati Hyvärinen, Satu Koskela, Riitta Niittyvuopio, Anne Nihtinen, Liisa Volin, Urpu Salmenniemi, Mervi Putkonen, Ismael Buño, David Gallardo, Maija Itälä-Remes, Jukka Partanen, Jarmo Ritari

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: GvHD, GWAS, gene expression, meta-analysis, HSCT, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2020.00019/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/5a01dc7926d04cf7b717b130211e553b

Computational Analysis of HLA-presentation of Non-synonymous Recipient Mismatches Indicates Effect on the Risk of Chronic Graft-vs.-Host Disease After Allogeneic HSCT

Authors: Jarmo Ritari, Kati Hyvärinen, Satu Koskela, Riitta Niittyvuopio, Anne Nihtinen, Urpu Salmenniemi, Mervi Putkonen, Liisa Volin, Tony Kwan, Tomi Pastinen, Maija Itälä-Remes, Jukka Partanen

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: whole-exome sequencing, HSCT, HLA, minor histocompatibility antigen, genomics, graft-vs.-host, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.01625/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/4caae628e34d40e295dd9ef0ded76eb0

Antilymphocyte globulin for matched sibling donor transplantation in patients with myelofibrosis

Authors: Marie Robin, Sylvie Chevret, Linda Koster, Christine Wolschke, Ibrahim Yakoub-Agha, Jean Henri Bourhis, Patrice Chevallier, Jan J. Cornelissen, Péter Reményi, Johan Maertens, Xavier Poiré, Charles Craddock, Gérard Socié, Maija Itälä-Remes, Harry C. Schouten, Tony Marchand, Jakob Passweg, Didier Blaise, Gandhi Damaj, Zubeyde Nur Ozkurt, Tsila Zuckerman, Thomas Cluzeau, Hélène Labussière-Wallet, Jörg Cammenga, Donal McLornan, Yves Chalandon, Nicolaus Kröger

Source: Haematologica, Vol 104, Iss 6 (2019)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/8937; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/78605200dfee49f8a66bffba2fce5fe6

Impact of extramedullary disease in patients with newly diagnosed multiple myeloma undergoing autologous stem cell transplantation: a study from the Chronic Malignancies Working Party of the EBMT

Authors: Nico Gagelmann, Diderik-Jan Eikema, Simona Iacobelli, Linda Koster, Hareth Nahi, Anne-Marie Stoppa, Tamás Masszi, Denis Caillot, Stig Lenhoff, Miklos Udvardy, Charles Crawley, William Arcese, Clara Mariette, Ann Hunter, Xavier Leleu, Martin Schipperus, Michel Delforge, Pietro Pioltelli, John A. Snowden, Maija Itälä-Remes, Maurizio Musso, Anja van Biezen, Laurent Garderet, Nicolaus Kröger

Source: Haematologica, Vol 103, Iss 5 (2018)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/8460; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/06bc03d29827406b9491d6f70c0b97bf

Early CD8+-recovery independently predicts low probability of disease relapse but also associates with severe GVHD after allogeneic HSCT.

Authors: Juha Ranti, Samu Kurki, Urpu Salmenniemi, Mervi Putkonen, Soile Salomäki, Maija Itälä-Remes

Source: PLoS ONE, Vol 13, Iss 9, p e0204136 (2018)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC6147489?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/ed46a18a12d04d1ab61d9757d353fa51

Graft immune cell composition associates with clinical outcome of allogeneic hematopoietic stem cell transplantation in patients with AML

Authors: Ulla Impola, Antti Larjo, Urpu Salmenniemi, Mervi Putkonen, Maija Itälä-Remes, Jukka Partanen

Source: Frontiers in Immunology, Vol 7 (2016)

Subject Terms: Transplantation, acute GVHD, AML, immune cells, chronic GVHD, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00523/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/d878882fd60f46be8fca0d46387a86e6

A prospective randomized trial comparing cyclosporine/methotrexate and tacrolimus/sirolimus as graft-versus-host disease prophylaxis after allogeneic hematopoietic stem cell transplantation

Authors: Johan Törlén, Olle Ringdén, Karin Garming-Legert, Per Ljungman, Jacek Winiarski, Kari Remes, Maija Itälä-Remes, Mats Remberger, Jonas Mattsson

Source: Haematologica, Vol 101, Iss 11 (2016)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/7886; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/43054f3c64974fec98ba1876667b39cd

Influence of invasive aspergillosis during acute leukaemia treatment on survival after allogeneic stem cell transplantation: a prospective study of the EBMT Infectious Diseases Working PartyResearch in context

Authors: Olaf Penack, Gloria Tridello, Urpu Salmenniemi, Rodrigo Martino, Nina Khanna, Katia Perruccio, Franca Fagioli, Monika Richert-Przygonska, Hélène Labussière-Wallet, Johan Maertens, Charlotte Jubert, Mahmoud Aljurf, Herbert Pichler, Gergely Kriván, Desiree Kunadt, Marina Popova, Melissa Gabriel, Elisabetta Calore, Igor Wolfgang Blau, Fabio Benedetti, Maija Itäla-Remes, Elizabeth de Kort, Domenico Russo, Maura Faraci, Anne-Lise Ménard, Peter von dem Borne, Xavier Poiré, Akif Yesilipek, Jolanta Gozdzik, Zeynep Arzu Yeğin, Lucrecia Yañez, Luca Facchini, Gwendolyn Van Gorkom, Lorenz Thurner, Ulker Kocak, Antònia Sampol, Tsila Zuckerman, Marc Bierings, Stephan Mielke, Fabio Ciceri, Lotus Wendel, Nina Knelange, Malgorzata Mikulska, Dina Averbuch, Jan Styczynski, Rafael de la Camara, Simone Cesaro

Source: EClinicalMedicine, Vol 67, Iss , Pp 102393- (2024)

Subject Terms: Invasive, Aspergillosis, Stem cell transplantation, Mortality, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589537023005709; https://doaj.org/toc/2589-5370

Access URL: https://doaj.org/article/e5d255140f7b46d3b99bf2de109b8e3d

Endothelial Activation and Stress Index (EASIX) to predict mortality after allogeneic stem cell transplantation: a prospective study

Authors: Axel Benner, Peter Dreger, Grzegorz W Basak, Christian Koenecke, Olaf Penack, Christophe Peczynski, Lucia López Corral, Ivan Moiseev, Hélène Schoemans, Zinaida Peric, Thomas Luft, Simona Sica, Mutlu Arat, Maija Itäla-Remes, Nicolaas P M Schaap, Michal Karas, Ludek Raida, Thomas Schroeder, Elisabetta Metafuni, Tulay Ozcelik, Brenda M Sandmaier, Lambros Kordelas

Source: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 1 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/12/1/e007635.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/60017a9b556c4c1eaccc5b562a3da144