Tolerance to 2,4-Dinitrofluorobenzene‒Induced Contact Hypersensitivity Is Mediated by CD73-Expressing Tissue-Homing Regulatory T Cells

Authors: Da, Meihong, Chen, Luxia, Enk, Alexander, Mahnke, Karsten

Source: In Journal of Investigative Dermatology June 2023 143(6):1011-1022

Topical Application of Adenosine A2-Type Receptor Agonists Prevents Contact Hypersensitivity Reactions in Mice by Affecting Skin Dendritic Cells

Authors: Silva-Vilches, Cinthia, Bolduan, Vanessa, Alabdullah, Mohamad, Steinbrink, Kerstin, Probst, Hans Christian, Enk, Alexander, Mahnke, Karsten

Source: In Journal of Investigative Dermatology March 2023 143(3):408-418

Protease‐ and cell type–specific activation of protease‐activated receptor 2 in cutaneous inflammation

Authors: Fleischer, Maria Isabel, Röhrig, Nadine, Raker, Verena K., Springer, Juliane, Becker, Detlef, Ritz, Sandra, Bros, Matthias, Stege, Henner, Haist, Maximilian, Grabbe, Stephan, Haub, Jessica, Becker, Christian, Reyda, Sabine, Disse, Jennifer, Schmidt, Talkea, Mahnke, Karsten, Weiler, Hartmut, Ruf, Wolfram ^*, Steinbrink, Kerstin

Source: In Journal of Thrombosis and Haemostasis December 2022 20(12):2823-2836

Antigen targeting to dendritic cells: Still a place in future immunotherapy?

Authors: Stoitzner, Patrizia, Romani, Nikolaus, Rademacher, Christoph, Probst, Hans Christian, Mahnke, Karsten

Source: European journal of immunology. 52(12):1909-1924

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100169751280.0x000001&indx=1&recIds=ETOCvdc_100169751280.0x000001

Regulatory T Cells Prevent Neutrophilic Infiltration of Skin during Contact Hypersensitivity Reactions by Strengthening the Endothelial Barrier

Authors: Ring, Sabine, Inaba, Yutaka, Da, Meihong, Bopp, Tobias, Grabbe, Stephan, Enk, Alexander, Mahnke, Karsten

Source: In Journal of Investigative Dermatology August 2021 141(8):2006-2017

Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells

Authors: Schaupp, Laura, Muth, Sabine, Rogell, Leif, Kofoed-Branzk, Michael, Melchior, Felix, Lienenklaus, Stefan, Ganal-Vonarburg, Stephanie C., Klein, Matthias, Guendel, Fabian, Hain, Tobias, Schütze, Kristian, Grundmann, Ulrike, Schmitt, Vanessa, Dorsch, Martina, Spanier, Julia, Larsen, Pia-Katharina, Schwanz, Thomas, Jäckel, Sven, Reinhardt, Christoph, Bopp, Tobias, Danckwardt, Sven, Mahnke, Karsten, Heinz, Gitta Anne, Mashreghi, Mir-Farzin, Durek, Pawel, Kalinke, Ulrich, Kretz, Oliver, Huber, Tobias B., Weiss, Siegfried, Wilhelm, Christoph, Macpherson, Andrew J., Schild, Hansjörg, Diefenbach, Andreas, Probst, Hans Christian

Source: In Cell 28 May 2020 181(5):1080-1096

Production of Extracellular Adenosine by CD73+ Dendritic Cells Is Crucial for Induction of Tolerance in Contact Hypersensitivity Reactions

Authors: Silva-Vilches, Cinthia, Ring, Sabine, Schrader, Jürgen, Clausen, Björn E., Probst, Hans-Christian, Melchior, Felix, Schild, Hansjörg, Enk, Alexander, Mahnke, Karsten

Source: In Journal of Investigative Dermatology March 2019 139(3):541-551

Dermal CD207-Negative Migratory Dendritic Cells Are Fully Competent to Prime Protective, Skin Homing Cytotoxic T-Lymphocyte Responses

Authors: Hain, Tobias, Melchior, Felix, Kamenjarin, Nadine, Muth, Sabine, Weslati, Hela, Clausen, Björn E., Mahnke, Karsten, Silva-Vilches, Cinthia, Schütze, Kristian, Sohl, Julian, Radsak, Markus P., Bündgen, Georg, Bopp, Tobias, Danckwardt, Sven, Schild, Hansjörg, Probst, Hans Christian

Source: In Journal of Investigative Dermatology February 2019 139(2):422-429

Adenosine and Its Receptors in the Pathogenesis and Treatment of Inflammatory Skin Diseases.

Authors: Chen, Luxia, Lei, Xuan, Mahnke, Karsten

Source: International Journal of Molecular Sciences; Jun2024, Vol. 25 Issue 11, p5810, 22p

Subject Terms: ADENOSINES, SKIN diseases, IMMUNOMODULATORS, CONTACT dermatitis, ADENOSINE triphosphate, PATHOGENESIS

The Dendritic Cell Receptor for Endocytosis, DEC-205, Can Recycle and Enhance Antigen Presentation via Major Histocompatibility Complex Class II-Positive Lysosomal Compartments

Authors: Mahnke, Karsten, Guo, Ming, Lee, Sena, Sepulveda, Homero, Swain, Suzy L., Nussenzweig, Michel, Steinman, Ralph M.

Source: The Journal of Cell Biology, 2000 Oct . 151(3), 673-683.

Access URL: https://www.jstor.org/stable/1620224

Down-Regulation of CD62L Shedding in T Cells by CD39+ Regulatory T Cells Leads to Defective Sensitization in Contact Hypersensitivity Reactions

Authors: Mahnke, Karsten, Useliene, Jurgina, Ring, Sabine, Kage, Paula, Jendrossek, Verena, Robson, Simon C., Bylaite-Bucinskiene, Matilda, Steinbrink, Kerstin, Enk, Alexander H.

Source: In Journal of Investigative Dermatology January 2017 137(1):106-114

Allergen-Specific Low Zone Tolerance Is Independent of MRP8/14-, TLR4-, TLR7-, and TLR9-Mediated Immune Processes

Authors: Schmidt, Talkea, Lorenz, Nadine, Raker, Verena K., Schmidgen, Maria I., Mahnke, Karsten, Enk, Alexander, Roth, Johannes, Steinbrink, Kerstin

Source: Journal of investigative dermatology. 138(2):452-455

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100071896396.0x000001&indx=1&recIds=ETOCvdc_100071896396.0x000001

Immunosuppressive therapy influences the accelerated age-dependent T-helper cell differentiation in systemic lupus erythematosus remission patients

Authors: Schaier, Matthias, Gottschalk, Claudius, Uhlmann, Lorenz, Speer, Claudius, Kälble, Florian, Eckstein, Volker, Müller-Tidow, Carsten, Meuer, Stefan, Mahnke, Karsten, Lorenz, Hanns-Martin, Zeier, Martin, Steinborn, Andrea

Source: Arthritis research & therapy. 20(1):1-17

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185355918.0x000001&indx=1&recIds=ETOCvdc_100185355918.0x000001

Immune Response After Radiofrequency Ablation and Surgical Resection in Nonsmall Cell Lung Cancer

Authors: Schneider, Thomas, Hoffmann, Hans, Dienemann, Hendrik, Herpel, Ester, Heussel, Claus Peter, Enk, Alexander H., Ring, Sabine, Mahnke, Karsten

Source: In Seminars in Thoracic and Cardiovascular Surgery Summer 2016 28(2):585-592

Adenosine, bridging chronic inflammation and tumor growth.

Authors: Luxia Chen, Alabdullah, Mohamad, Mahnke, Karsten

Source: Frontiers in Immunology; 2023, p1-13, 13p

Subject Terms: TUMOR growth, ADENOSINES, INFLAMMATION, IMMUNOSUPPRESSION, IMMUNE response

Regulatory T Cell—Derived Adenosine Induces Dendritic Cell Migration through the Epac-Rap1 Pathway

Authors: Ring, Sabine, Pushkarevskaya, Anna, Schild, Hansjörg, Probst, Hans Christian, Jendrossek, Verena, Wirsdörfer, Florian, Ledent, Catherine, Robson, Simon Christopher, Enk, Alexander H., Mahnke, Karsten

Source: Journal of immunology. 194(8):3735-3744

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN600576730&indx=1&recIds=ETOCRN600576730

Regulatory T Cells Stimulate B7-H1 Expression in Myeloid-Derived Suppressor Cells in ret Melanomas

Authors: Fujimura, Taku ^*, Ring, Sabine, Umansky, Viktor, Mahnke, Karsten, Enk, Alexander H.

Source: In Journal of Investigative Dermatology April 2012 132(4):1239-1246

Non-small Cell Lung Cancer Induces an Immunosuppressive Phenotype of Dendritic Cells in Tumor Microenvironment by Upregulating B7-H3

Authors: Schneider, Thomas, Hoffmann, Hans, Dienemann, Hendrik, Schnabel, Philipp A., Enk, Alexander H., Ring, Sabine, Mahnke, Karsten

Source: In Journal of Thoracic Oncology July 2011 6(7):1162-1168

Regulatory T Cells from IL-10-Deficient Mice Fail to Suppress Contact Hypersensitivity Reactions Due to Lack of Adenosine Production

Authors: Ring, Sabine ^*, Enk, Alexander H., Mahnke, Karsten

Source: In Journal of Investigative Dermatology July 2011 131(7):1494-1502

Small for gestational age (SGA) neonates show reduced suppressive activity of their regulatory T cells

Authors: Steinborn, Andrea, Engst, Martina, Haensch, Gertrud Maria, Mahnke, Karsten, Schmitt, Edgar, Meuer, Stefan, Sohn, Christof

Source: In Clinical Immunology 2010 134(2):188-197