Subpopulations of regulatory T cells are associated with subclinical atherosclerotic plaques, levels of LDL, and cardiorespiratory fitness in the elderly

Authors: Tim Böttrich, Pascal Bauer, Vincent Gröβer, Magdalena Huber, Hartmann Raifer, Torsten Frech, Svenja Nolte, Theresa Dombrowski, Franz Cemic, Natascha Sommer, Robert Ringseis, Klaus Eder, Karsten Krüger, Christopher Weyh

Source: Journal of Sport and Health Science, Vol 13, Iss 3, Pp 288-296 (2024)

Subject Terms: Cardiorespiratory fitness, Elderly, Regulatory T cells, Subclinical atherosclerosis, Sports, GV557-1198.995, Sports medicine, RC1200-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2095254623001138; https://doaj.org/toc/2095-2546

Access URL: https://doaj.org/article/e58ccd71a67e46b5b75615be62a8c963

SAMD1 suppresses epithelial-mesenchymal transition pathways in pancreatic ductal adenocarcinoma.

Authors: Clara Simon, Inka D Brunke, Bastian Stielow, Ignasi Forné, Anna Mary Steitz, Merle Geller, Iris Rohner, Lisa Marie Weber, Sabrina Fischer, Lea Marie Jeude, Theresa Huber, Andrea Nist, Thorsten Stiewe, Magdalena Huber, Malte Buchholz, Robert Liefke

Source: PLoS Biology, Vol 22, Iss 8, p e3002739 (2024)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/0154901bedc94acf98fd143354555040

T-bet+ B cells are activated by and control endogenous retroviruses through TLR-dependent mechanisms

Authors: Eileen Rauch, Timm Amendt, Aleksandra Lopez Krol, Fabian B. Lang, Vincent Linse, Michelle Hohmann, Ann-Christin Keim, Susanne Kreutzer, Kevin Kawengian, Malte Buchholz, Philipp Duschner, Saskia Grauer, Barbara Schnierle, Andreas Ruhl, Ingo Burtscher, Sonja Dehnert, Chege Kuria, Alexandra Kupke, Stephanie Paul, Thomas Liehr, Marcus Lechner, Markus Schnare, Andreas Kaufmann, Magdalena Huber, Thomas H. Winkler, Stefan Bauer, Philipp Yu

Source: Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/614f814272ae48b086e1c7fdf428b850

CRISPR/Cas9-mediated nexilin deficiency interferes with cardiac contractile function in zebrafish in vivo

Authors: Janessa Hofeichner, Bernd Martin Gahr, Magdalena Huber, Alena Boos, Wolfgang Rottbauer, Steffen Just

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/e08620d4a73f433e931fbe5cc9844ed3

Reciprocal crosstalk between Th17 and mesothelial cells promotes metastasis‐associated adhesion of ovarian cancer cells

Authors: Felix Neuhaus, Sonja Lieber, Veronika Shinkevich, Anna Mary Steitz, Hartmann Raifer, Kathrin Roth, Florian Finkernagel, Thomas Worzfeld, Andreas Burchert, Corinna Keber, Andrea Nist, Thorsten Stiewe, Silke Reinartz, Vanessa M. Beutgen, Johannes Graumann, Kim Pauck, Holger Garn, Matthias Gaida, Rolf Müller, Magdalena Huber

Source: Clinical and Translational Medicine, Vol 14, Iss 4, Pp n/a-n/a (2024)

Subject Terms: mesothelial cells, metastasis, ovarian carcinoma, Th17 cells, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2001-1326

Access URL: https://doaj.org/article/34a4cb60682e4aa7997d2f9cd82ee079

TRAIL-dependent apoptosis of peritoneal mesothelial cells by NK cells promotes ovarian cancer invasion

Authors: Anna Mary Steitz, Clarissa Schröder, Isabel Knuth, Corinna U. Keber, Leah Sommerfeld, Florian Finkernagel, Julia M. Jansen, Uwe Wagner, Sabine Müller-Brüsselbach, Thomas Worzfeld, Magdalena Huber, Vanessa M. Beutgen, Johannes Graumann, Elke Pogge von Strandmann, Rolf Müller, Silke Reinartz

Source: iScience, Vol 26, Iss 12, Pp 108401- (2023)

Subject Terms: Microenvironment, Immunology, Cancer, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004223024781; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/e9c08e3135684fc89cfce67f8891a099

AIM2 promotes TH17 cells differentiation by regulating RORγt transcription activity

Authors: Jefferson Antônio Leite, Luísa Menezes, Eloisa Martins, Tamara Silva Rodrigues, Lucas Tavares, Anna Ebering, Carsten Schelmbauer, Guilherme C. Martelossi Cebinelli, Valeriya Zinina, Artemiy Golden, Natalia Soshnikova, Dario S. Zamboni, Fernando Q. Cunha, Magdalena Huber, João Santana Silva, Ari Waisman, Daniela Carlos, Niels Olsen Saraiva Câmara

Source: iScience, Vol 26, Iss 11, Pp 108134- (2023)

Subject Terms: Biological sciences, Cell biology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004223022113; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/4aa4b8055f9049c997033944049dce04

Methyltransferase-like 3 (METTL3) inhibition potentiates anti-tumor immunity: a novel strategy for improving anti-PD1 therapy

Authors: Anna Brichkina, Roman Suezov, Magdalena Huber

Source: Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-2 (2023)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/7e1f900e4a0f4af8aee7ba1090beabf3

T-cell-derived TNF-α and a cluster of immunological parameters from plasma allow a separation between SARS-CoV-2 convalescent versus vaccinated elite athletes

Authors: Jana Palmowski, Sarah Kohnhorst, Pascal Bauer, Christian Puta, Simon Haunhorst, Kristina Gebhardt, Thomas Reichel, Christian Keller, Magdalena Huber, Hartmann Raifer, Karsten Krüger

Source: Frontiers in Physiology, Vol 14 (2023)

Subject Terms: T-lymphocyte, SARS-CoV-2, vaccination, convalescence, elite athletes, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2023.1203983/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/977d2ee5b76d4bab93bdbed290e7a044

Antibody escape and global spread of SARS-CoV-2 lineage A.27

Authors: Tamara Kaleta, Lisa Kern, Samuel Leandro Hong, Martin Hölzer, Georg Kochs, Julius Beer, Daniel Schnepf, Martin Schwemmle, Nena Bollen, Philipp Kolb, Magdalena Huber, Svenja Ulferts, Sebastian Weigang, Gytis Dudas, Alice Wittig, Lena Jaki, Abdou Padane, Adamou Lagare, Mounerou Salou, Egon Anderson Ozer, Ndodo Nnaemeka, John Kofi Odoom, Robert Rutayisire, Alia Benkahla, Chantal Akoua-Koffi, Abdoul-Salam Ouedraogo, Etienne Simon-Lorière, Vincent Enouf, Stefan Kröger, Sébastien Calvignac-Spencer, Guy Baele, Marcus Panning, Jonas Fuchs

Source: Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/95413bc995ee4d938afb0a7f4c3cfaa7

Detection and functional resolution of soluble immune complexes by an FcγR reporter cell panel

Authors: Haizhang Chen, Andrea Maul‐Pavicic, Martin Holzer, Magdalena Huber, Ulrich Salzer, Nina Chevalier, Reinhard E Voll, Hartmut Hengel, Philipp Kolb

Source: EMBO Molecular Medicine, Vol 14, Iss 1, Pp 1-17 (2021)

Subject Terms: immune complexes, Fc‐gamma receptors, FcγR activation, SLE, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/d3c81898e97a42de975a99761a93314a

Microbial short-chain fatty acids modulate CD8+ T cell responses and improve adoptive immunotherapy for cancer

Authors: Maik Luu, Zeno Riester, Adrian Baldrich, Nicole Reichardt, Samantha Yuille, Alessandro Busetti, Matthias Klein, Anne Wempe, Hanna Leister, Hartmann Raifer, Felix Picard, Khalid Muhammad, Kim Ohl, Rossana Romero, Florence Fischer, Christian A. Bauer, Magdalena Huber, Thomas M. Gress, Matthias Lauth, Sophia Danhof, Tobias Bopp, Thomas Nerreter, Imke E. Mulder, Ulrich Steinhoff, Michael Hudecek, Alexander Visekruna

Source: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/b049d4b46e18405fa995dd666bce268c

Lipid Storage and Interferon Response Determine the Phenotype of Ground Glass Hepatocytes in Mice and HumansSummary

Authors: Yuri Churin, Karuna Irungbam, Christoph S. Imiela, David Schwarz, Hans-Joachim Mollenkopf, Uta Drebber, Margarete Odenthal, Oleg Pak, Magdalena Huber, Dieter Glebe, Martin Roderfeld, Elke Roeb

Source: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 383-394 (2021)

Subject Terms: Hepatitis B, GGH, Surface Proteins, Intracellular Aggregates, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X21000618; https://doaj.org/toc/2352-345X

Access URL: https://doaj.org/article/5d731b4ed5db4b48a5a43b963f5c152e

Utility and Drawbacks of Chimeric Antigen Receptor T Cell (CAR-T) Therapy in Lung Cancer

Authors: Prameela Kandra, Rajender Nandigama, Bastian Eul, Magdalena Huber, Sebastian Kobold, Werner Seeger, Friedrich Grimminger, Rajkumar Savai

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: adaptive therapy, CAR-T cells, lung cancer, tumor-associated target antigens, toxicities, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.903562/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/0cf61627a2184e12bada2c09c02cbad4

IL18 Receptor Signaling Inhibits Intratumoral CD8+ T-Cell Migration in a Murine Pancreatic Cancer Model

Authors: Elena Nasiri, Malte Student, Katrin Roth, Nadya Siti Utami, Magdalena Huber, Malte Buchholz, Thomas M. Gress, Christian Bauer

Source: Cells, Vol 12, Iss 3, p 456 (2023)

Subject Terms: live cell imaging, intravital two-photon microscopy animal models for intravital imaging, T-cell migration, tumor spheroid coculture model, pausing phases/arrest coefficient, fluorophore, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/12/3/456; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/39f184cb59d640c1976c25d95e4731e2

Pictorial Review on Imaging Findings in Cerebral CTP in Patients with Acute Stroke and Its Mimics: A Primer for General Radiologists

Authors: Benedikt Haggenmüller, Kornelia Kreiser, Nico Sollmann, Magdalena Huber, Daniel Vogele, Stefan A. Schmidt, Meinrad Beer, Bernd Schmitz, Yigit Ozpeynirci, Johannes Rosskopf, Christopher Kloth

Source: Diagnostics, Vol 13, Iss 3, p 447 (2023)

Subject Terms: computed tomography, CT perfusion, stroke, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/2075-4418/13/3/447; https://doaj.org/toc/2075-4418

Access URL: https://doaj.org/article/dad62214da334d0d995edeeb07e911ea

Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease

Authors: Judith Lang, Patrick Bohn, Hilal Bhat, Holger Jastrow, Bernd Walkenfort, Feyza Cansiz, Julian Fink, Michael Bauer, Dominik Olszewski, Ana Ramos-Nascimento, Vikas Duhan, Sarah-Kim Friedrich, Katrin Anne Becker, Adalbert Krawczyk, Michael J. Edwards, Andreas Burchert, Magdalena Huber, Justa Friebus-Kardash, Joachim R. Göthert, Cornelia Hardt, Hans Christian Probst, Fabian Schumacher, Karl Köhrer, Burkhard Kleuser, Eduard B. Babiychuk, Beate Sodeik, Jürgen Seibel, Urs F. Greber, Philipp A. Lang, Erich Gulbins, Karl S. Lang

Source: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/ce87beeac86246829e4b47c4ed971f39

IL-17+ CD8+ T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis

Authors: Christina Lückel, Felix Picard, Hartmann Raifer, Lucia Campos Carrascosa, Anna Guralnik, Yajuan Zhang, Matthias Klein, Stefan Bittner, Falk Steffen, Sonja Moos, Federico Marini, Renee Gloury, Florian C. Kurschus, Ying-Yin Chao, Wilhelm Bertrams, Veronika Sexl, Bernd Schmeck, Lynn Bonetti, Melanie Grusdat, Michael Lohoff, Christina E. Zielinski, Frauke Zipp, Axel Kallies, Dirk Brenner, Michael Berger, Tobias Bopp, Björn Tackenberg, Magdalena Huber

Source: Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/2e2f0c2356834c5db881aabfe09b997c

Novel GM-CSF signals via IFN-γR/IRF-1 and AKT/mTOR license monocytes for suppressor function

Authors: Eliana Ribechini, James A. Hutchinson, Sabine Hergovits, Marion Heuer, Jörg Lucas, Ulrike Schleicher, Ana-Laura Jordán Garrote, Sarah J. Potter, Paloma Riquelme, Heike Brackmann, Nora Müller, Hartmann Raifer, Ingolf Berberich, Magdalena Huber, Andreas Beilhack, Michael Lohoff, Christian Bogdan, Matthias Eyrich, Heike M. Hermanns, Edward K. Geissler, Manfred B. Lutz

Source: Blood Advances, Vol 1, Iss 14, Pp 947-960 (2017)

Subject Terms: Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2473952920302068; https://doaj.org/toc/2473-9529

Access URL: https://doaj.org/article/01939da1159e4606bd40390d8e10d0d3

Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4

Authors: Lucia Campos Carrascosa, Matthias Klein, Yohko Kitagawa, Christina Lückel, Federico Marini, Anika König, Anna Guralnik, Hartmann Raifer, Stefanie Hagner-Benes, Diana Rädler, Andreas Böck, Cholho Kang, Michael Lohoff, Holger Garn, Bianca Schaub, Friederike Berberich-Siebelt, Shimon Sakaguchi, Tobias Bopp, Magdalena Huber

Source: Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/13172fb84a7445059a0849047683d7fa