Drosophila Evolution over Space and Time (DEST): A New Population Genomics Resource

Authors: Kapun, Martin, Nunez, Joaquin C B, Bogaerts-Márquez, María, Murga-Moreno, Jesús, Paris, Margot, Outten, Joseph, Coronado-Zamora, Marta, Tern, Courtney, Rota-Stabelli, Omar, Guerreiro, Maria P García, Casillas, Sònia, Orengo, Dorcas J, Puerma, Eva, Kankare, Maaria, Ometto, Lino, Loeschcke, Volker, Onder, Banu S, Abbott, Jessica K, Schaeffer, Stephen W, Rajpurohit, Subhash, Behrman, Emily L, Schou, Mads F, Merritt, Thomas J S, Lazzaro, Brian P, Glaser-Schmitt, Amanda, Argyridou, Eliza, Staubach, Fabian, Wang, Yun, Tauber, Eran, Serga, Svitlana V, Fabian, Daniel K, Dyer, Kelly A, Wheat, Christopher W, Parsch, John, Grath, Sonja, Veselinovic, Marija Savic, Stamenkovic-Radak, Marina, Jelic, Mihailo, Buendía-Ruíz, Antonio J, Gómez-Julián, Maria Josefa, Espinosa-Jimenez, Maria Luisa, Gallardo-Jiménez, Francisco D, Patenkovic, Aleksandra, Eric, Katarina, Tanaskovic, Marija, Ullastres, Anna, Guio, Lain, Merenciano, Miriam, Guirao-Rico, Sara, Horváth, Vivien, Obbard, Darren J, Pasyukova, Elena, Alatortsev, Vladimir E, Vieira, Cristina P, Vieira, Jorge, Torres, Jorge Roberto, Kozeretska, Iryna, Maistrenko, Oleksandr M, Montchamp-Moreau, Catherine, Mukha, Dmitry V, Machado, Heather E, Lamb, Keric, Paulo, Tânia, Yusuf, Leeban, Barbadilla, Antonio, Petrov, Dmitri, Schmidt, Paul, Gonzalez, Josefa, Flatt, Thomas, Bergland, Alan O

Source: Molecular biology and evolution. 38(12):5782-5805

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138375052.0x000001&indx=1&recIds=ETOCvdc_100138375052.0x000001

Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion

Authors: Tovy, Ayala, Reyes, Jaime M., Gundry, Michael C., Brunetti, Lorenzo, Lee-Six, Henry, Petljak, Mia, Park, Hyun Jung, Guzman, Anna G., Rosas, Carina, Jeffries, Aaron R., Baple, Emma, Mill, Jonathan, Crosby, Andrew H., Sency, Valerie, Xin, Baozhong, Machado, Heather E., Castillo, Danielle, Weitzel, Jeffrey N., Li, Wei, Stratton, Michael R., Campbell, Peter J., Wang, Heng, Sanders, Mathijs A., Goodell, Margaret A.

Source: Cell stem cell. 27(2):326-335.e4

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117334055.0x000001&indx=1&recIds=ETOCvdc_100117334055.0x000001

Convergent somatic evolution commences in utero in a germline ribosomopathy.

Authors: Machado, Heather E., Øbro, Nina F., Williams, Nicholas, Tan, Shengjiang, Boukerrou, Ahmed Z., Davies, Megan, Belmonte, Miriam, Mitchell, Emily, Baxter, E. Joanna, Mende, Nicole, Clay, Anna, Ancliff, Philip, Köglmeier, Jutta, Killick, Sally B., Kulasekararaj, Austin, Meyer, Stefan, Laurenti, Elisa, Campbell, Peter J., Kent, David G., Nangalia, Jyoti

Source: Nature Communications; 8/22/2023, Vol. 14 Issue 1, p1-14, 14p

Subject Terms: CONVERGENT evolution, SOMATIC mutation, HEMATOPOIETIC stem cells, WHOLE genome sequencing, GERM cells

Pervasive Strong Selection at the Level of Codon Usage Bias in Drosophila melanogaster.

Authors: Machado, Heather E.¹, machadoheather@gmail.com, Lawrie, David S.², Petrov, Dmitri A.³

Source: Genetics; Feb2020, Vol. 214 Issue 2, p511-528, 18p

Interspecific Profiling of Gene Expression Informed by Comparative Genomic Hybridization: A Review and a Novel Approach in African Cichlid Fishes

Authors: Machado, Heather E., Pollen, Alexander A., Hofmann, Hans A., Renn, Suzy C. P.

Source: Integrative and Comparative Biology, 2009 Dec 01. 49(6), 644-659.

Access URL: https://www.jstor.org/stable/40405997

Intraspecific variation in gene expression under prolonged drought in Piriqueta hybrids and their parental taxa

Authors: Machado, Heather E., Cruzan, Mitchell B.

Source: In Plant Science 2010 178(5):429-439

Gene expression signatures of mating system evolution.

Authors: Renn, Suzy C.P.¹, Machado, Heather E.^1,2, Duftner, Nina³, Sessa, Anna K.³, Harris, Rayna M.^3,4, Hofmann, Hans A.^3,4,5, Olson, Bradley

Source: Genome. 2018, Vol. 61 Issue 4, p287-297. 11p.

Subject Terms: *CICHLIDS, *BIODIVERSITY, *ANIMAL sexual behavior, *PHENOTYPES, *GENE expression

Diverse mutational landscapes in human lymphocytes.

Authors: Machado, Heather E., Mitchell, Emily, Øbro, Nina F., Kübler, Kirsten, Davies, Megan, Leongamornlert, Daniel, Cull, Alyssa, Maura, Francesco, Sanders, Mathijs A., Cagan, Alex T. J., McDonald, Craig, Belmonte, Miriam, Shepherd, Mairi S., Vieira Braga, Felipe A., Osborne, Robert J., Mahbubani, Krishnaa, Martincorena, Iñigo, Laurenti, Elisa, Green, Anthony R., Getz, Gad

Source: Nature; Aug2022, Vol. 608 Issue 7924, p724-732, 9p

A critical assessment of cross-species detection of gene duplicates using comparative genomic hybridization

Authors: Renn Suzy CP, Machado Heather E

Source: BMC Genomics, Vol 11, Iss 1, p 304 (2010)

Subject Terms: Biotechnology, TP248.13-248.65, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.biomedcentral.com/1471-2164/11/304; https://doaj.org/toc/1471-2164

Access URL: https://doaj.org/article/4de4d8d44bee429eb6088fbca9745ca5

Using comparative genomic hybridization to survey genomic sequence divergence across species: a proof-of-concept from Drosophila

Authors: Kulathinal Rob J, Soneji Kosha, Jones Albyn, Machado Heather E, Renn Suzy CP, Hofmann Hans A

Source: BMC Genomics, Vol 11, Iss 1, p 271 (2010)

Subject Terms: Biotechnology, TP248.13-248.65, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.biomedcentral.com/1471-2164/11/271; https://doaj.org/toc/1471-2164

Access URL: https://doaj.org/article/234f1b37c22144dbb472ae1518a6bb6e

Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila.

Authors: Machado, Heather E.^1,2 heather.machado@sanger.ac.uk, Bergiand, Alan O.^1,3 aob2x@virginia.edu, Taylor, Ryan¹, Tilk, Susanne¹, Behrman, Emily⁴, Dyer, Kelly⁵, Fabian, Daniel K.^6,7, Flatt, Thomas^6,8, González, Josefa⁹, Karasov, Talia L.¹⁰, Kim, Bernard¹, Kozeretska, Iryna^11,12, Lazzaro, Brian P.¹³, Merritt, Thomas J. S.¹⁴, Pool, John E.¹⁵, O'Brien, Katherine⁴, Rajpurohit, Subhash⁴, Roy, Paula R.¹⁶, Schaeffer, Stephen W.¹⁷, Serga, Svitlana^11,12

Source: eLife. 7/1/2021, p1-21. 21p.

Subject Terms: *SEASONS, *CHROMOSOME inversions, *GENETIC variation, *DROSOPHILA, *DROSOPHILA melanogaster, *GENE frequency, *GROWING season

Geographic Terms: NORTH America

Somatic mutation landscapes at single-molecule resolution.

Authors: Abascal, Federico, Harvey, Luke M. R., Mitchell, Emily, Lawson, Andrew R. J., Lensing, Stefanie V., Ellis, Peter, Russell, Andrew J. C., Alcantara, Raul E., Baez-Ortega, Adrian, Wang, Yichen, Kwa, Eugene Jing, Lee-Six, Henry, Cagan, Alex, Coorens, Tim H. H., Chapman, Michael Spencer, Olafsson, Sigurgeir, Leonard, Steven, Jones, David, Machado, Heather E., Davies, Megan

Source: Nature; 5/20/2021, Vol. 593 Issue 7859, p405-410, 6p

Clonal Dynamics of Normal Haematopoiesis with Human Ageing

Authors: Mitchell, Emily, Spencer Chapman, Michael, Williams, Nicholas, Dawson, Kevin J, Mende, Nicole, Calderbank, Emily, Jung, Hyunchul, Mitchell, Thomas J, Coorens, Tim, Spencer, David, Machado, Heather E, Lee-Six, Henry, Davies, Megan, Hayler, Daniel, Fabre, Margarete Alice, Mahbubani, Krishnaa, Abascal, Federico, Vassiliou, George S., Baxter, Joanna E, Martincorena, Inigo, Stratton, Michael, Kent, David G., Chatterjee, Krishna, Saeb-Parsy, Kourosh, Green, Anthony R, Nangalia, Jyoti, Laurenti, Elisa, Campbell, Peter J.

Source: In Blood 23 November 2021 138 Supplement 1:598-598

Gene duplication in an African cichlid adaptive radiation.

Authors: Machado, Heather E.¹ machadoheather@gmail.com, Jui, Ginger² ginger.jui@gmail.com, Joyce, Domino A.³ d.joyce@hull.ac.uk, Reilly III, Christian R. L.⁴ Christian.Reilly@santacatalina.org, Lunt, David H.³ d.h.lunt@hull.ac.uk, Renn, Suzy C. P.² renns@reed.edu

Source: BMC Genomics. 2014, Vol. 15 Issue 1, p1-25. 25p.

Subject Terms: *CICHLIDS, *GENOMICS, *CHROMOSOME duplication, *ADENOSINE triphosphate, *BIODIVERSITY

Geographic Terms: LAKE Nyasa

Life History of Normal Human Lymphocytes Revealed By Somatic Mutations

Authors: Machado, Heather E ^*, Øbro, Nina Friesgaard ^*, Mitchell, Emily ^*, Davies, Megan ^*, Green, Anthony R, Saeb-Parsy, Kourosh ^*, Hodson, Daniel James, Kent, David ^*, Campbell, Peter J ^*

Source: In Blood 13 November 2019 134 Supplement 1:1045-1045

This result is not displayed to guests.
Login for full access.

A critical assessment of cross-species detection of gene duplicates using comparative genomic hybridization.

Authors: Machado, Heather E., Renn, Suzy C.P.

Source: BMC Genomics; 2010, Vol. 11, p304-312, 9p

Subject Terms: GENETICS, BIOLOGICAL evolution, GENOMES, DNA, BIOLOGICAL variation, IN situ hybridization

Using comparative genomic hybridization to survey genomic sequence divergence across species: a proof-of-concept from Drosophila.

Authors: Renn, Suzy C. P., Machado, Heather E., Jones, Albyn, Soneji, Kosha, Kulathinal, Rob J., Hofmann, Hans A.

Source: BMC Genomics; 2010, Vol. 11, p271-282, 12p

Subject Terms: BIOLOGICAL divergence, DROSOPHILA, NUCLEOTIDE sequence, BIOLOGICAL variation, BIOLOGICAL evolution, SPECIES diversity