Lipoprotein(a) and the atherosclerotic burden – Should we wait for clinical trial evidence before taking action?

Authors: Fichtner, Isabella, Macchi, Chiara, Rizzuto, Alessandra Stefania, Carugo, Stefano, Corsini, Alberto, Ruscica, Massimiliano

Source: In Atherosclerosis Plus December 2024 58:16-23

Indoor air pollution impacts cardiovascular autonomic control during sleep and the inflammatory profile

Authors: Carandina, Angelica, Fanti, Giacomo, Carminati, Alessio, Baroni, Michele, Salafia, Greta, Arosio, Beatrice, Macchi, Chiara, Ruscica, Massimiliano, Vicenzi, Marco, Carugo, Stefano, Borghi, Francesca, Spinazzè, Andrea, Cavallo, Domenico Maria, Tobaldini, Eleonora, Montano, Nicola, Bonzini, Matteo

Source: In Environmental Research 1 November 2024 260

Advancements in risk stratification and management strategies in primary cardiovascular prevention

Authors: Barkas, Fotios, Sener, Yusuf Ziya, Golforoush, Pelin Arabacilar, Kheirkhah, Azin, Rodriguez-Sanchez, Elena, Novak, Jan, Apellaniz-Ruiz, Maria, Akyea, Ralph Kwame, Bianconi, Vanessa, Ceasovschih, Alexandr, Chee, Ying Jie, Cherska, Mariia, Chora, Joana Rita, D'Oria, Mario, Demikhova, Nadiia, Kocyigit Burunkaya, Duygu, Rimbert, Antoine, Macchi, Chiara, Rathod, Krishnaraj, Roth, Lynn, Sukhorukov, Vasily, Stoica, Svetlana, Scicali, Roberto, Storozhenko, Tatyana, Uzokov, Jamol, Lupo, Maria Giovanna, van der Vorst, Emiel P.C., Porsch, Florentina

Source: In Atherosclerosis August 2024 395

Exploring the role of epicardial adipose-tissue-derived extracellular vesicles in cardiovascular diseases

Authors: Rizzuto, Alessandra Stefania, Gelpi, Guido, Mangini, Andrea, Carugo, Stefano, Ruscica, Massimiliano, Macchi, Chiara

Source: In iScience 19 April 2024 27(4)

Anticancer Activity of Delta-Tocotrienol in Human Hepatocarcinoma: Involvement of Autophagy Induction.

Authors: Montagnani Marelli, Marina¹ (AUTHOR) chiara.macchi@unimi.it, Macchi, Chiara¹ (AUTHOR) massimiliano.ruscica@unimi.it, Ruscica, Massimiliano^1,2 (AUTHOR) roberta.moretti@unimi.it, Sartori, Patrizia³ (AUTHOR) patrizia.sartori@unimi.it, Moretti, Roberta Manuela¹ (AUTHOR)

Source: Cancers. Aug2024, Vol. 16 Issue 15, p2654. 20p.

Subject Terms: *THERAPEUTIC use of antineoplastic agents, *IN vitro studies, *LIVER tumors, *EPITHELIAL cells, *AUTOPHAGY, *DRUG resistance in cancer cells, *MITOCHONDRIA, *APOPTOSIS, *NECROSIS, *IN vivo studies, *CANCER cell culture, *CELLULAR signal transduction, *OXIDATIVE stress, *DESCRIPTIVE statistics, *REACTIVE oxygen species, *VITAMIN E, *CELL death, *LIVER, *HEPATOCELLULAR carcinoma, *LIVER transplantation

PGC1-α-driven mitochondrial biogenesis contributes to a cancer stem cell phenotype in melanoma

Authors: Fontana, Fabrizio ^{a, ⁎}, Macchi, Chiara ^a, Anselmi, Martina ^a, Rizzuto, Alessandra Stefania ^b, Ruscica, Massimiliano ^{a, c}, Limonta, Patrizia ^a

Source: In BBA - Molecular Basis of Disease January 2024 1870(1)

Prognostic Value of PCSK9 Levels in Premenopausal Women at Risk of Breast Cancer—Evidence from a 17-Year Follow-Up Study.

Authors: Ruscica, Massimiliano^1,2 (AUTHOR) massimiliano.ruscica@unimi.it, Macchi, Chiara¹ (AUTHOR) chiara.macchi@unimi.it, Gandini, Sara³ (AUTHOR) sara.gandini@ieo.it, Macis, Debora⁴ (AUTHOR) debora.macis@ieo.it, Guerrieri-Gonzaga, Aliana⁴ (AUTHOR) aliana.guerrierigonzaga@ieo.it, Aristarco, Valentina⁴ (AUTHOR) valentina.aristarco@ieo.it, Serrano, Davide⁴ (AUTHOR) davide.serrano@ieo.it, Lazzeroni, Matteo⁴ (AUTHOR) matteo.lazzeroni@ieo.it, Rizzuto, Alessandra Stefania⁵ (AUTHOR) alessandra.rizzuto@unimi.it, Gaeta, Aurora^3,6 (AUTHOR) aurora.gaeta@ieo.it, Corsini, Alberto¹ (AUTHOR) alberto.corsini@unimi.it, Gulisano, Marcella⁷ (AUTHOR) marcella.gulisano@gmail.com, Johansson, Harriet⁴ (AUTHOR) bernardo.bonanni@ieo.it, Bonanni, Bernardo⁴ (AUTHOR)

Source: Cancers. Apr2024, Vol. 16 Issue 7, p1411. 11p.

Subject Terms: *BREAST cancer prognosis, *BREAST tumor risk factors, *RISK assessment, *PERIMENOPAUSE, *PREDICTIVE tests, *HDL cholesterol, *ANTILIPEMIC agents, *WOMEN, *SECONDARY analysis, *BODY mass index, *RESEARCH funding, *SCIENTIFIC observation, *TUMOR markers, *DESCRIPTIVE statistics, *PROTEASE inhibitors, *LONGITUDINAL method, *ESTRADIOL, *LOW density lipoproteins, *CHOLESTEROL, *PROGRESSION-free survival, *CONFIDENCE intervals, *TRIGLYCERIDES, *REGRESSION analysis, *PROPORTIONAL hazards models

Pollution from fine particulate matter and atherosclerosis: A narrative review

Authors: Macchi, Chiara, Sirtori, Cesare R., Corsini, Alberto, Mannuccio Mannucci, Pier, Ruscica, Massimiliano

Source: In Environment International May 2023 175

Low Lipoprotein(a) Levels Predict Hepatic Fibrosis in Patients With Nonalcoholic Fatty Liver Disease

Authors: Meroni, Marica, Longo, Miriam, Lombardi, Rosa, Paolini, Erika, Macchi, Chiara, Corsini, Alberto, Sirtori, Cesare R., Fracanzani, Anna Ludovica, Ruscica, Massimiliano, Dongiovanni, Paola

Source: Hepatology communications. 6(3):535-549

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100142231178.0x000001&indx=1&recIds=ETOCvdc_100142231178.0x000001

A Glass Half Full: Critical Assessment of EU Regulation 2017/821 on Conflict Minerals

Authors: Macchi, Chiara

Source: Journal of human rights practice. 13(2):270-290

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100148818698.0x000001&indx=1&recIds=ETOCvdc_100148818698.0x000001

Tour de Table: Farm to Fork Law Update

Authors: Schebesta, Hanna, Alessandrini, Mirta, Cazzini, Francesco, Macchi, Chiara, Plana-Casado, Maria José, Rolandi, Silvia

Source: European food and feed law review. 17(3):208-218

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN629649333&indx=1&recIds=ETOCRN629649333

TM6SF2/PNPLA3/MBOAT7 Loss-of-Function Genetic Variants Impact on NAFLD Development and Progression Both in Patients and in In Vitro Models

Authors: Longo, Miriam, Meroni, Marica, Paolini, Erika, Erconi, Veronica, Carli, Fabrizia, Fortunato, Francesco, Ronchi, Dario, Piciotti, Roberto, Sabatini, Silvia, Macchi, Chiara, Alisi, Anna, Miele, Luca, Soardo, Giorgio, Comi, Giacomo Pietro, Valenti, Luca, Ruscica, Massimiliano, Fracanzani, Anna L., Gastaldelli, Amalia, Dongiovanni, Paola

Source: In Cellular and Molecular Gastroenterology and Hepatology 2022 13(3):759-788

Proprotein Convertase Subtilisin/Kexin Type 9: A View beyond the Canonical Cholesterol-Lowering Impact

Authors: Macchi, Chiara, Ferri, Nicola, Sirtori, Cesare R., Corsini, Alberto, Banach, Maciej, Ruscica, Massimiliano

Source: In The American Journal of Pathology August 2021 191(8):1385-1397

Mitochondrial dynamics and nonalcoholic fatty liver disease (NAFLD): new perspectives for a fairy-tale ending?

Authors: Longo, Miriam, Meroni, Marica, Paolini, Erika, Macchi, Chiara, Dongiovanni, Paola

Source: In Metabolism April 2021 117

An association study of cyclase‐associated protein 2 and frailty.

Authors: Pelucchi, Silvia¹ (AUTHOR), Macchi, Chiara¹ (AUTHOR), D'Andrea, Laura¹ (AUTHOR), Rossi, Paolo Dionigi^2,3 (AUTHOR), Speciani, Michela Carola⁴ (AUTHOR), Stringhi, Ramona¹ (AUTHOR), Ruscica, Massimiliano^1,5 (AUTHOR), Arosio, Beatrice⁶ (AUTHOR), Di Luca, Monica¹ (AUTHOR), Cesari, Matteo⁶ (AUTHOR), Edefonti, Valeria^4,7 (AUTHOR) valeria.edefonti@unimi.it, Marcello, Elena¹ (AUTHOR) elena.marcello@unimi.it

Source: Aging Cell. Sep2023, Vol. 22 Issue 9, p1-5. 5p.

Subject Terms: *FRAILTY, *AGE, *OLDER people, *REGRESSION analysis, *PROTEINS, *MOLECULAR pathology

Geographic Terms: MILAN (Italy)

Circulating PCSK9 as a prognostic biomarker of cardiovascular events in individuals with type 2 diabetes: evidence from a 16.8-year follow-up study.

Authors: Ruscica, Massimiliano^1,2 (AUTHOR) massimiliano.ruscica@unimi.it, Macchi, Chiara¹ (AUTHOR), Giuliani, Angelica³ (AUTHOR), Rizzuto, Alessandra Stefania⁴ (AUTHOR), Ramini, Deborah⁵ (AUTHOR), Sbriscia, Matilde³ (AUTHOR), Carugo, Stefano^2,4 (AUTHOR), Bonfigli, Anna Rita⁶ (AUTHOR), Corsini, Alberto¹ (AUTHOR), Olivieri, Fabiola^3,5 (AUTHOR), Sabbatinelli, Jacopo^3,7 (AUTHOR) j.sabbatinelli@univpm.it

Source: Cardiovascular Diabetology. 8/24/2023, Vol. 22 Issue 1, p1-12. 12p.

Subject Terms: *TYPE 2 diabetes, *MAJOR adverse cardiovascular events, *DIABETIC nephropathies, *CARDIOVASCULAR diseases, *BIOMARKERS, *DYSLIPIDEMIA

Business and human rights implications of climate change litigation: Milieudefensie et al. v Royal Dutch Shell

Authors: Macchi, Chiara, Zeben, Josephine

Source: Review of European, comparative & international environmental law. 30(3):409-415

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135922089.0x000001&indx=1&recIds=ETOCvdc_100135922089.0x000001

Conceptualizing just transition litigation.

Authors: Savaresi, Annalisa, Setzer, Joana, Bookman, Sam, Bouwer, Kim, Chan, Tiffanie, Keuschnigg, Isabela, Armeni, Chiara, Harrington, Alexandra, Heri, Corina, Higham, Ian, Hilson, Chris, Luporini, Riccardo, Macchi, Chiara, Nordlander, Linnéa, Obani, Pedi, Peterson, Lauri, Schapper, Andrea, Ghaleigh, Navraj Singh, Tigre, Maria Antonia, Wewerinke-Singh, Margaretha

Source: Nature Sustainability; Nov2024, Vol. 7 Issue 11, p1379-1384, 6p

Leptin, Resistin, and Proprotein Convertase Subtilisin/Kexin Type 9: The Role of STAT3

Authors: Macchi, Chiara, Greco, Maria Francesca, Botta, Margherita, Sperandeo, Paola, Dongiovanni, Paola, Valenti, Luca, Cicero, Arrigo F.G., Borghi, Claudio, Lupo, Maria Giovanna, Romeo, Stefano, Corsini, Alberto, Magni, Paolo, Ferri, Nicola, Ruscica, Massimiliano

Source: In The American Journal of Pathology November 2020 190(11):2226-2236

Sex-specific predictors of PCSK9 levels in a European population: The IMPROVE study

Authors: Ferri, Nicola, Ruscica, Massimiliano, Coggi, Daniela, Bonomi, Alice, Amato, Mauro, Frigerio, Beatrice, Sansaro, Daniela, Ravani, Alessio, Veglia, Fabrizio, Capra, Nicolò, Lupo, Maria G., Macchi, Chiara, Castelnuovo, Samuela, Savonen, Kai, Silveira, Angela, Kurl, Sudhir, Giral, Philippe, Pirro, Matteo, Strawbridge, Rona J., Gigante, Bruna, Smit, Andries J., Tremoli, Elena, Colombo, Gualtiero I., Baldassarre, Damiano

Source: In Atherosclerosis September 2020 309:39-46